PH31252A - Process for the preparation of sterile amoxycilin sodium salt. - Google Patents

Process for the preparation of sterile amoxycilin sodium salt.

Info

Publication number: PH31252A
Authority: PH; Philippines
Prior art keywords: sterile; preparation; amoxycilin; sodium salt; solution
Prior art date: 1992-10-05

Application number

PH47015A

Other languages

English (en)

Inventor

Giordano B Corsi

Brandt Alberto

Cecchetelli Loredana

Original Assignee

Istituto Biochimico Italiano

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-10-05

Filing date

1993-10-05

Publication date

1998-06-18

1993-10-05 Application filed by Istituto Biochimico Italiano filed Critical Istituto Biochimico Italiano

1998-06-18 Publication of PH31252A publication Critical patent/PH31252A/en

Links

238000000034 method Methods 0.000 title abstract 2
-1 amoxycilin sodium salt Chemical class 0.000 title 1
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 2
LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 abstract 2
229910052708 sodium Inorganic materials 0.000 abstract 2
239000011734 sodium Substances 0.000 abstract 2
XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 abstract 1
KXKVLQRXCPHEJC-UHFFFAOYSA-N acetic acid trimethyl ester Natural products COC(C)=O KXKVLQRXCPHEJC-UHFFFAOYSA-N 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
229960003022 amoxicillin Drugs 0.000 abstract 1
150000007942 carboxylates Chemical class 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 abstract 1
239000002244 precipitate Substances 0.000 abstract 1
238000000926 separation method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/04—Preparation
- C07D499/14—Preparation of salts
- C07D499/16—Preparation of salts of alkali or alkaline earth metals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PH47015A 1992-10-05 1993-10-05 Process for the preparation of sterile amoxycilin sodium salt. PH31252A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITMI922296A IT1255716B (it)	1992-10-05	1992-10-05	Procedimento per la preparazione di antibiotici beta-lattamici sterili

Publications (1)

Publication Number	Publication Date
PH31252A true PH31252A (en)	1998-06-18

Family

ID=11364060

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH47015A PH31252A (en)	1992-10-05	1993-10-05	Process for the preparation of sterile amoxycilin sodium salt.

Country Status (13)

Country	Link
US (1)	US5559241A (de)
EP (1)	EP0596262B1 (de)
JP (1)	JPH072869A (de)
KR (1)	KR970010068B1 (de)
AT (1)	ATE138381T1 (de)
AU (1)	AU674021B2 (de)
DE (1)	DE69302793T2 (de)
DK (1)	DK0596262T3 (de)
ES (1)	ES2089667T3 (de)
GR (1)	GR3020834T3 (de)
IT (1)	IT1255716B (de)
NZ (1)	NZ248853A (de)
PH (1)	PH31252A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW347383B (en) *	1995-10-26	1998-12-11	Biochemie Gmbh	A process for the production of a crystalline sodium salt of amoxicillin in ethanol as solvent
US6073052A (en) *	1996-11-15	2000-06-06	Zelickson; Brian D.	Device and method for treatment of gastroesophageal reflux disease
CN1182138C (zh) *	1998-06-01	2004-12-29	史密丝克莱恩比彻姆公司	制备结晶阿莫西林盐的方法
IN191580B (de)	1999-12-17	2003-12-06	Ranbaxy Lab Ltd
ITMI20011718A1 (it)	2001-08-03	2003-02-03	Istituto Biochimico Italiano	Processo per la preparazione del sale sodico dell'acido-6(d-(-)-alpha-(4-etil-2,3-diosso-1-piperazinocarbonilammino)fenilacetammido)penicill
ITMI20051630A1 (it) *	2005-09-02	2007-03-03	Acs Dobfar Spa	Formulazione farmaceutica sterile iniettabile contenente almeno due principi attivi
EP2582708A4 (de) *	2010-06-16	2014-01-15	Vardhman Chemtech Ltd	Verbessertes verfahren zur herstellung von amoxicillinnatrium
JP7322568B2 (ja) *	2019-07-25	2023-08-08	カシオ計算機株式会社	メモリシステム、制御方法及びプログラム

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE639104A (de) *	1962-11-02
GB1543317A (en) *	1976-08-04	1979-04-04	Beecham Group Ltd	Process for the preparation of sodium amoxycillin
US4387051A (en) *	1979-10-29	1983-06-07	Beecham Group Limited	β-Lactam antibiotics, their preparation and their use in pharmaceutical compositions
FR2503710B1 (fr) *	1981-04-10	1985-07-05	Bristol Myers Co	Procede de production du sel de sodium de l'amoxicilline
EP0131147B2 (de) *	1983-06-10	1996-12-04	Beecham Group p.l.c.	Kristallines Amoxycillin-Salz
ES8606871A1 (es) *	1985-10-21	1986-06-01	Antibioticos Sa	Un procedimiento de preparacion de amoxicilina sodica

1992
- 1992-10-05 IT ITMI922296A patent/IT1255716B/it active IP Right Grant
1993
- 1993-10-04 KR KR1019930020444A patent/KR970010068B1/ko not_active Expired - Fee Related
- 1993-10-04 DE DE69302793T patent/DE69302793T2/de not_active Expired - Fee Related
- 1993-10-04 AT AT93115972T patent/ATE138381T1/de not_active IP Right Cessation
- 1993-10-04 EP EP93115972A patent/EP0596262B1/de not_active Expired - Lifetime
- 1993-10-04 ES ES93115972T patent/ES2089667T3/es not_active Expired - Lifetime
- 1993-10-04 NZ NZ248853A patent/NZ248853A/en not_active IP Right Cessation
- 1993-10-04 AU AU48760/93A patent/AU674021B2/en not_active Ceased
- 1993-10-04 DK DK93115972.7T patent/DK0596262T3/da active
- 1993-10-05 JP JP5271238A patent/JPH072869A/ja active Pending
- 1993-10-05 PH PH47015A patent/PH31252A/en unknown
1995
- 1995-09-15 US US08/528,546 patent/US5559241A/en not_active Expired - Lifetime
1996
- 1996-08-21 GR GR960402196T patent/GR3020834T3/el unknown

Also Published As

Publication number	Publication date
GR3020834T3 (en)	1996-11-30
ATE138381T1 (de)	1996-06-15
KR970010068B1 (ko)	1997-06-20
EP0596262B1 (de)	1996-05-22
US5559241A (en)	1996-09-24
ITMI922296A0 (it)	1992-10-05
KR940009206A (ko)	1994-05-20
ES2089667T3 (es)	1996-10-01
EP0596262A1 (de)	1994-05-11
DK0596262T3 (da)	1996-10-07
AU4876093A (en)	1994-04-21
JPH072869A (ja)	1995-01-06
DE69302793D1 (de)	1996-06-27
IT1255716B (it)	1995-11-10
DE69302793T2 (de)	1997-01-23
AU674021B2 (en)	1996-12-05
NZ248853A (en)	1995-10-26
ITMI922296A1 (it)	1994-04-05

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