PL1709063T3 - Glikozylowane pochodne steroidowe o aktywności antymigracyjnej - Google Patents

Glikozylowane pochodne steroidowe o aktywności antymigracyjnej

Info

Publication number
PL1709063T3
PL1709063T3 PL04820440T PL04820440T PL1709063T3 PL 1709063 T3 PL1709063 T3 PL 1709063T3 PL 04820440 T PL04820440 T PL 04820440T PL 04820440 T PL04820440 T PL 04820440T PL 1709063 T3 PL1709063 T3 PL 1709063T3
Authority
PL
Poland
Prior art keywords
steroid derivatives
migratory activity
glycosylated steroid
glycosylated
migratory
Prior art date
Application number
PL04820440T
Other languages
English (en)
Inventor
Jean-Claude Braekman
Laurent Ingrassia
Prosper Nshimyumukiza
Quaquebeke Eric Van
Welle Janique De
Den Hove Laurent Van
Robert Kiss
Francis Darro
Original Assignee
Unibioscreen Sa
Univ Bruxelles
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2003/014567 external-priority patent/WO2004055039A1/en
Application filed by Unibioscreen Sa, Univ Bruxelles filed Critical Unibioscreen Sa
Publication of PL1709063T3 publication Critical patent/PL1709063T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0095—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 carbon in position 21 is part of carboxylic group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
PL04820440T 2003-12-18 2004-12-17 Glikozylowane pochodne steroidowe o aktywności antymigracyjnej PL1709063T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/EP2003/014567 WO2004055039A1 (en) 2002-12-18 2003-12-18 Steroid compounds with anti-tumor activity
EP2004006486 2004-06-16
EP04820440A EP1709063B1 (en) 2003-12-18 2004-12-17 Glycosylated steroid derivatives with anti-migratory activity
PCT/EP2004/014408 WO2005058934A2 (en) 2003-12-18 2004-12-17 Glycosylated steroid derivatives with anti-migratory activity

Publications (1)

Publication Number Publication Date
PL1709063T3 true PL1709063T3 (pl) 2008-06-30

Family

ID=34702157

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04820440T PL1709063T3 (pl) 2003-12-18 2004-12-17 Glikozylowane pochodne steroidowe o aktywności antymigracyjnej

Country Status (10)

Country Link
EP (1) EP1709063B1 (pl)
AU (1) AU2004299267A1 (pl)
CA (1) CA2549074A1 (pl)
DE (1) DE602004011574T2 (pl)
DK (1) DK1709063T3 (pl)
ES (1) ES2300877T3 (pl)
MX (1) MXPA06006901A (pl)
PL (1) PL1709063T3 (pl)
PT (1) PT1709063E (pl)
WO (1) WO2005058934A2 (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI373473B (en) * 2005-09-02 2012-10-01 Otsuka Pharma Co Ltd Anticancer agent
US8921328B2 (en) 2010-09-14 2014-12-30 Glycomimetics, Inc. E-selectin antagonists
KR102055958B1 (ko) 2011-12-22 2019-12-13 글리코미메틱스, 인크. E-셀렉틴 길항제 화합물, 조성물, 및 이용 방법
CA2888527A1 (en) * 2012-10-31 2014-05-08 Glycomimetics, Inc. E-selectin antagonists compounds and methods of use
US9867841B2 (en) 2012-12-07 2018-01-16 Glycomimetics, Inc. Compounds, compositions and methods using E-selectin antagonists for mobilization of hematopoietic cells
JP6689854B2 (ja) 2014-12-03 2020-04-28 グリコミメティクス， インコーポレイテッド Ｅ−セレクチンおよびｃｘｃｒ４ケモカイン受容体のヘテロ二官能性阻害剤
WO2017151708A1 (en) 2016-03-02 2017-09-08 Glycomimetics, Inc. Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin
US11433086B2 (en) 2016-08-08 2022-09-06 Glycomimetics, Inc. Combination of T-cell checkpoint inhibitors with inhibitors of e-selectin or CXCR4, or with heterobifunctional inhibitors of both E-selectin and CXCR4
AU2017341065B2 (en) 2016-10-07 2023-04-06 Crescent Biopharma, Inc. Highly potent multimeric E-selectin antagonists
EP3596096A1 (en) 2017-03-15 2020-01-22 GlycoMimetics, Inc. Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists
JP7275131B2 (ja) 2017-11-30 2023-05-17 グリコミメティクス， インコーポレイテッド 骨髄浸潤リンパ球を動員する方法、およびその使用
KR20200104889A (ko) 2017-12-29 2020-09-04 글리코미메틱스, 인크. E-셀렉틴 및 갈렉틴-3의 이종이기능성 억제제
KR20200128025A (ko) 2018-03-05 2020-11-11 글리코미메틱스, 인크. 급성 골수성 백혈병 및 관련 병태의 치료 방법
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0940690A (ja) * 1995-05-23 1997-02-10 Yutaka Sashita ステロイド配糖体及びこれを有効成分とする医薬
JP2001002698A (ja) * 1999-06-16 2001-01-09 Kanegafuchi Chem Ind Co Ltd 新規腫瘍細胞増殖抑制剤

Also Published As

Publication number Publication date
PT1709063E (pt) 2008-04-09
DE602004011574D1 (de) 2008-03-13
WO2005058934A3 (en) 2005-10-06
MXPA06006901A (es) 2006-09-04
DE602004011574T2 (de) 2009-01-29
CA2549074A1 (en) 2005-06-30
ES2300877T3 (es) 2008-06-16
EP1709063B1 (en) 2008-01-23
EP1709063A2 (en) 2006-10-11
WO2005058934A2 (en) 2005-06-30
DK1709063T3 (da) 2008-06-02
AU2004299267A1 (en) 2005-06-30

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