PL1709063T3 - Glikozylowane pochodne steroidowe o aktywności antymigracyjnej - Google Patents
Glikozylowane pochodne steroidowe o aktywności antymigracyjnejInfo
- Publication number
- PL1709063T3 PL1709063T3 PL04820440T PL04820440T PL1709063T3 PL 1709063 T3 PL1709063 T3 PL 1709063T3 PL 04820440 T PL04820440 T PL 04820440T PL 04820440 T PL04820440 T PL 04820440T PL 1709063 T3 PL1709063 T3 PL 1709063T3
- Authority
- PL
- Poland
- Prior art keywords
- steroid derivatives
- migratory activity
- glycosylated steroid
- glycosylated
- migratory
- Prior art date
Links
- 230000002095 anti-migrative effect Effects 0.000 title 1
- 150000003431 steroids Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0095—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 carbon in position 21 is part of carboxylic group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2003/014567 WO2004055039A1 (en) | 2002-12-18 | 2003-12-18 | Steroid compounds with anti-tumor activity |
| EP2004006486 | 2004-06-16 | ||
| PCT/EP2004/014408 WO2005058934A2 (en) | 2003-12-18 | 2004-12-17 | Glycosylated steroid derivatives with anti-migratory activity |
| EP04820440A EP1709063B1 (en) | 2003-12-18 | 2004-12-17 | Glycosylated steroid derivatives with anti-migratory activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1709063T3 true PL1709063T3 (pl) | 2008-06-30 |
Family
ID=34702157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04820440T PL1709063T3 (pl) | 2003-12-18 | 2004-12-17 | Glikozylowane pochodne steroidowe o aktywności antymigracyjnej |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1709063B1 (pl) |
| AU (1) | AU2004299267A1 (pl) |
| CA (1) | CA2549074A1 (pl) |
| DE (1) | DE602004011574T2 (pl) |
| DK (1) | DK1709063T3 (pl) |
| ES (1) | ES2300877T3 (pl) |
| MX (1) | MXPA06006901A (pl) |
| PL (1) | PL1709063T3 (pl) |
| PT (1) | PT1709063E (pl) |
| WO (1) | WO2005058934A2 (pl) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI373473B (en) * | 2005-09-02 | 2012-10-01 | Otsuka Pharma Co Ltd | Anticancer agent |
| US8921328B2 (en) | 2010-09-14 | 2014-12-30 | Glycomimetics, Inc. | E-selectin antagonists |
| SI2794626T1 (en) | 2011-12-22 | 2018-02-28 | Glycomimetics, Inc. | E-SELECTINE ANTAGONIST COMPOUNDS |
| JP2016501840A (ja) * | 2012-10-31 | 2016-01-21 | グリコミメティクス， インコーポレイテッド | Ｅ−セレクチンアンタゴニスト化合物および使用方法 |
| LT2928476T (lt) | 2012-12-07 | 2018-05-25 | Glycomimetics, Inc. | Junginiai, kompozicijos ir būdai, naudojant e-selektino antagonistus, hemopoetinių ląstelių mobilizacijai |
| HUE045542T2 (hu) | 2014-12-03 | 2019-12-30 | Glycomimetics Inc | E-szelektinek és CXCR4 kemokin receptorok heterobifunkcionális inhibitorai |
| WO2017151708A1 (en) | 2016-03-02 | 2017-09-08 | Glycomimetics, Inc. | Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin |
| EP3497131B1 (en) | 2016-08-08 | 2022-03-09 | GlycoMimetics, Inc. | Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4. |
| CA3037850A1 (en) | 2016-10-07 | 2018-04-12 | Glycomimetics, Inc. | Highly potent multimeric e-selectin antagonists |
| CA3054605A1 (en) | 2017-03-15 | 2018-09-20 | Glycomimetics, Inc. | Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists |
| EP3717013A1 (en) | 2017-11-30 | 2020-10-07 | GlycoMimetics, Inc. | Methods of mobilizing marrow infiltrating lymphocytes and uses thereof |
| EP3732186A1 (en) | 2017-12-29 | 2020-11-04 | GlycoMimetics, Inc. | Heterobifunctional inhibitors of e-selectin and galectin-3 |
| US11707474B2 (en) | 2018-03-05 | 2023-07-25 | Glycomimetics, Inc. | Methods for treating acute myeloid leukemia and related conditions |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0940690A (ja) * | 1995-05-23 | 1997-02-10 | Yutaka Sashita | ステロイド配糖体及びこれを有効成分とする医薬 |
| JP2001002698A (ja) * | 1999-06-16 | 2001-01-09 | Kanegafuchi Chem Ind Co Ltd | 新規腫瘍細胞増殖抑制剤 |
-
2004
- 2004-12-17 PL PL04820440T patent/PL1709063T3/pl unknown
- 2004-12-17 MX MXPA06006901A patent/MXPA06006901A/es active IP Right Grant
- 2004-12-17 PT PT04820440T patent/PT1709063E/pt unknown
- 2004-12-17 DK DK04820440T patent/DK1709063T3/da active
- 2004-12-17 CA CA002549074A patent/CA2549074A1/en not_active Abandoned
- 2004-12-17 WO PCT/EP2004/014408 patent/WO2005058934A2/en not_active Ceased
- 2004-12-17 AU AU2004299267A patent/AU2004299267A1/en not_active Abandoned
- 2004-12-17 ES ES04820440T patent/ES2300877T3/es not_active Expired - Lifetime
- 2004-12-17 EP EP04820440A patent/EP1709063B1/en not_active Expired - Lifetime
- 2004-12-17 DE DE602004011574T patent/DE602004011574T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005058934A2 (en) | 2005-06-30 |
| MXPA06006901A (es) | 2006-09-04 |
| AU2004299267A1 (en) | 2005-06-30 |
| DE602004011574D1 (de) | 2008-03-13 |
| ES2300877T3 (es) | 2008-06-16 |
| PT1709063E (pt) | 2008-04-09 |
| DK1709063T3 (da) | 2008-06-02 |
| CA2549074A1 (en) | 2005-06-30 |
| DE602004011574T2 (de) | 2009-01-29 |
| EP1709063A2 (en) | 2006-10-11 |
| EP1709063B1 (en) | 2008-01-23 |
| WO2005058934A3 (en) | 2005-10-06 |
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