PL1803440T3 - Preparat farmaceutyczny zawierający mikrokapsułki statyn w zawiesinie w estrach alkilowych wielonienasyconych kwasów tłuszczowych (PUFA) - Google Patents

Preparat farmaceutyczny zawierający mikrokapsułki statyn w zawiesinie w estrach alkilowych wielonienasyconych kwasów tłuszczowych (PUFA)

Info

Publication number
PL1803440T3
PL1803440T3 PL05802903T PL05802903T PL1803440T3 PL 1803440 T3 PL1803440 T3 PL 1803440T3 PL 05802903 T PL05802903 T PL 05802903T PL 05802903 T PL05802903 T PL 05802903T PL 1803440 T3 PL1803440 T3 PL 1803440T3
Authority
PL
Poland
Prior art keywords
pufa
microcapsules
alkyl esters
polyunsaturated fatty
asids
Prior art date
Application number
PL05802903T
Other languages
English (en)
Inventor
Paolo Carminati
Antonio Parente
Original Assignee
Gp Pharm Sa
Defiante Farm S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gp Pharm Sa, Defiante Farm S A filed Critical Gp Pharm Sa
Publication of PL1803440T3 publication Critical patent/PL1803440T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL05802903T 2004-10-19 2005-10-13 Preparat farmaceutyczny zawierający mikrokapsułki statyn w zawiesinie w estrach alkilowych wielonienasyconych kwasów tłuszczowych (PUFA) PL1803440T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200402492A ES2255426B1 (es) 2004-10-19 2004-10-19 Formulacion farmaceutica que comprende microcapsulas de estatinas suspendidas en ester alquilicos de acidos grasos poliinsaturados (pufa).
EP05802903A EP1803440B1 (en) 2004-10-19 2005-10-13 Pharmaceutical formulation comprising microcapsules of statins suspended in alkyl esters of polyunsaturated fatty asids (pufa)
PCT/ES2005/000542 WO2006045865A1 (es) 2004-10-19 2005-10-13 Formulación farmacéutica que comprende microcapsulas de estatinas suspendidas en ester alquílicos de ácidos grasos poliinsaturados (pufa)

Publications (1)

Publication Number Publication Date
PL1803440T3 true PL1803440T3 (pl) 2010-12-31

Family

ID=36227494

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05802903T PL1803440T3 (pl) 2004-10-19 2005-10-13 Preparat farmaceutyczny zawierający mikrokapsułki statyn w zawiesinie w estrach alkilowych wielonienasyconych kwasów tłuszczowych (PUFA)

Country Status (22)

Country Link
US (1) US20090196920A1 (pl)
EP (1) EP1803440B1 (pl)
JP (1) JP4976302B2 (pl)
KR (1) KR101413339B1 (pl)
CN (2) CN102727462A (pl)
AT (1) ATE469641T1 (pl)
AU (1) AU2005298587B2 (pl)
BR (1) BRPI0516152A (pl)
CA (1) CA2583756C (pl)
CY (1) CY1110751T1 (pl)
DE (1) DE602005021668D1 (pl)
DK (1) DK1803440T3 (pl)
EA (1) EA012371B1 (pl)
ES (2) ES2255426B1 (pl)
IL (1) IL182466A (pl)
MX (1) MX2007004655A (pl)
NZ (1) NZ554265A (pl)
PL (1) PL1803440T3 (pl)
PT (1) PT1803440E (pl)
SI (1) SI1803440T1 (pl)
WO (1) WO2006045865A1 (pl)
ZA (1) ZA200703509B (pl)

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Also Published As

Publication number Publication date
ES2255426A1 (es) 2006-06-16
IL182466A0 (en) 2007-07-24
WO2006045865A1 (es) 2006-05-04
DK1803440T3 (da) 2010-10-04
KR20070083715A (ko) 2007-08-24
IL182466A (en) 2013-06-27
EA012371B1 (ru) 2009-10-30
AU2005298587B2 (en) 2010-08-05
CN101043873A (zh) 2007-09-26
ES2255426B1 (es) 2007-08-16
EP1803440A1 (en) 2007-07-04
KR101413339B1 (ko) 2014-06-27
CN102727462A (zh) 2012-10-17
SI1803440T1 (sl) 2010-10-29
EA200700614A1 (ru) 2007-10-26
JP2008517040A (ja) 2008-05-22
CA2583756A1 (en) 2006-05-04
BRPI0516152A (pt) 2008-08-26
CA2583756C (en) 2013-12-24
PT1803440E (pt) 2010-08-31
DE602005021668D1 (de) 2010-07-15
JP4976302B2 (ja) 2012-07-18
MX2007004655A (es) 2008-03-10
ES2347055T3 (es) 2010-10-25
AU2005298587A1 (en) 2006-05-04
ZA200703509B (en) 2008-09-25
US20090196920A1 (en) 2009-08-06
ATE469641T1 (de) 2010-06-15
EP1803440B1 (en) 2010-06-02
NZ554265A (en) 2010-12-24
CY1110751T1 (el) 2015-06-10

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