PL1863487T5 - Leczenie objawów choroby Parkinsona z zastosowaniem nieimidazolowych alkiloaminowych ligandów receptora histaminowego H3 - Google Patents

Leczenie objawów choroby Parkinsona z zastosowaniem nieimidazolowych alkiloaminowych ligandów receptora histaminowego H3

Info

Publication number: PL1863487T5
Authority: PL; Poland
Prior art keywords: parkinson; symptoms; disease; treatment; receptor ligands
Prior art date: 2005-04-01

Application number

PL06744466T

Other languages

English (en)

Other versions

PL1863487T3 (pl

Inventor

Jean-Charles Schwartz

Jeanne-Marie Lecomte

Original Assignee

Bioprojet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-04-01

Filing date

2006-03-30

Publication date

2021-08-09

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35169680&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1863487(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-03-30 Application filed by Bioprojet filed Critical Bioprojet

2014-10-31 Publication of PL1863487T3 publication Critical patent/PL1863487T3/pl

2021-08-09 Publication of PL1863487T5 publication Critical patent/PL1863487T5/pl

Links

RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title 2
102000004384 Histamine H3 receptors Human genes 0.000 title 1
108090000981 Histamine H3 receptors Proteins 0.000 title 1
208000018737 Parkinson disease Diseases 0.000 title 1
-1 imidazole alkylamines Chemical class 0.000 title 1
239000003446 ligand Substances 0.000 title 1
208000024891 symptom Diseases 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pulmonology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PL06744466T 2005-04-01 2006-03-30 Leczenie objawów choroby Parkinsona z zastosowaniem nieimidazolowych alkiloaminowych ligandów receptora histaminowego H3 PL1863487T5 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
EP05290727A EP1707203A1 (en)	2005-04-01	2005-04-01	Treatment of parkinson's disease obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3- receptor ligands
US66861805P	2005-04-06	2005-04-06
PCT/IB2006/000739 WO2006103546A2 (en)	2005-04-01	2006-03-30	Treatment of parkinson's disease, obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine h3-receptor ligands
EP06744466.1A EP1863487B2 (en)	2005-04-01	2006-03-30	Treatment of symptoms of parkinson's disease with non-imidazole alkylamines histamine h3-receptor ligands

Publications (2)

Publication Number	Publication Date
PL1863487T3 PL1863487T3 (pl)	2014-10-31
PL1863487T5 true PL1863487T5 (pl)	2021-08-09

Family

ID=35169680

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL06744466T PL1863487T5 (pl)	2005-04-01	2006-03-30	Leczenie objawów choroby Parkinsona z zastosowaniem nieimidazolowych alkiloaminowych ligandów receptora histaminowego H3

Country Status (27)

Country	Link
US (1)	US8486947B2 (pl)
EP (2)	EP1707203A1 (pl)
JP (3)	JP5546761B2 (pl)
KR (1)	KR101308527B1 (pl)
CN (1)	CN101171009B (pl)
AU (1)	AU2006228413C1 (pl)
BR (1)	BRPI0612216B1 (pl)
CA (1)	CA2603656C (pl)
CY (1)	CY1114636T1 (pl)
DK (1)	DK1863487T4 (pl)
EA (1)	EA016007B1 (pl)
ES (1)	ES2426008T5 (pl)
HR (1)	HRP20130748T4 (pl)
MA (1)	MA29353B1 (pl)
ME (1)	ME01713B (pl)
MX (1)	MX2007012162A (pl)
NO (1)	NO343603B1 (pl)
NZ (1)	NZ561940A (pl)
PL (1)	PL1863487T5 (pl)
PT (1)	PT1863487E (pl)
RS (1)	RS52911B2 (pl)
SG (1)	SG147415A1 (pl)
SI (1)	SI1863487T2 (pl)
TN (1)	TNSN07365A1 (pl)
UA (1)	UA94902C2 (pl)
WO (1)	WO2006103546A2 (pl)
ZA (1)	ZA200708086B (pl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2655604C (en)	2006-06-23	2016-08-09	Abbott Laboratories	Cyclopropyl amine derivatives
US9108948B2 (en)	2006-06-23	2015-08-18	Abbvie Inc.	Cyclopropyl amine derivatives
FR2903904A1 (fr) *	2006-07-21	2008-01-25	Bioprojet Soc Civ Ile	Association de modafinil et d'un antagoniste ou agoniste inverse du recepteur h3
EP2502918B1 (en)	2006-07-25	2015-03-25	Cephalon, Inc.	Pyridazinone Derivatives
US8153813B2 (en)	2007-12-20	2012-04-10	Abbott Laboratories	Benzothiazole and benzooxazole derivatives and methods of use
EP2250176B1 (en)	2008-01-30	2012-08-01	Cephalon, Inc.	Substituted spirocyclic piperidine derivatives as histamine-3 (h3) receptor ligands
FR2932479A1 (fr)	2008-06-13	2009-12-18	Servier Lab	Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US9186353B2 (en)	2009-04-27	2015-11-17	Abbvie Inc.	Treatment of osteoarthritis pain
US8853390B2 (en)	2010-09-16	2014-10-07	Abbvie Inc.	Processes for preparing 1,2-substituted cyclopropyl derivatives
US9181275B2 (en)	2011-08-11	2015-11-10	Abbvie Inc.	Mercaptoamidine derivatives and methods of use
WO2013151982A1 (en)	2012-04-03	2013-10-10	Arena Pharmaceuticals, Inc.	Methods and compounds useful in treating pruritus, and methods for identifying such compounds
KR20150064743A (ko) *	2012-10-05	2015-06-11	트랜스테크 파르마 엘엘씨	경도 및 중등도 알츠하이머 병의 치료
EP3391886A1 (en)	2017-04-19	2018-10-24	Novartis AG	The use of a h3r inverse agonist for the treatment of shift work disorder
US20200281522A1 (en)	2019-03-06	2020-09-10	Medtronic Xomed, LLC	System and method for improved obstructive sleep apnea diagnostic for implantable devices
EP4248969A1 (en)	2022-03-23	2023-09-27	Bioprojet	Use of pitolisant for treating severe fatigue
JP2026511788A (ja)	2023-03-31	2026-04-14	ビオプロジェ・ファルマ	ピトリサント塩酸塩の多形形態
CN122374013A (zh)	2023-10-16	2026-07-10	生物计划制药公司	替洛利生的新制剂和使用方法

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5815945A (ja) *	1981-07-21	1983-01-29	Teikoku Hormone Mfg Co Ltd	新規なフエノキシアルキルアミン誘導体
FR2579596B1 (fr)	1985-03-26	1987-11-20	Inst Nat Sante Rech Med	(imidazolyl-4) piperidines, leur preparation et leur application en therapeutique
FR2671083B1 (fr)	1990-12-31	1994-12-23	Inst Nat Sante Rech Med	Nouvelles 4-(4-imidazolyl) piperidines substituees en 1, leur preparation ainsi que leurs applications therapeutiques.
EP0573542B1 (en)	1991-02-27	1997-10-15	Seed Capital Investments( Sci) B.V.	Imidazole-derivatives having antagonistic activity on the histamine h3-receptor
NZ246434A (en)	1991-12-18	1996-02-27	Schering Corp	Imidazoylalkyl substituted by a six membered nitrogen containing heterocycle; pharmaceutical compositions and preparatory methods
DE69212844T2 (de)	1991-12-18	1997-01-09	Schering Corp., Kenilworth, N.J.	Imidazolyl oder imidazolylalkyl substituiert mit einem 4- oder 5-gliedrigen stickstoff enthaltenden heterozyklischen ring
FR2686084B1 (fr)	1992-01-10	1995-12-22	Bioprojet Soc Civ	Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques.
US5380858A (en)	1992-04-01	1995-01-10	The University Of Toledo	Process for the preparation of intermediates useful for the synthesis of histamine receptor antagonists
US5486526A (en) *	1992-04-01	1996-01-23	The University Of Toledo	Histamine H3 -receptor antagonists and therapeutic uses thereof
US5639775A (en)	1992-04-01	1997-06-17	The University Of Toledo	4-[4'-piperodinyl or 3'-pirrolidinyl] substituted imidazoles as H3 -receptor antagonists and therapeutic uses thereof
KR960701858A (ko)	1993-01-25	1996-03-28	가와노 다케히코	이미다졸계 화합물(Imidazole-series compound)
JP3522790B2 (ja)	1993-06-08	2004-04-26	花王株式会社	Ｈ３−レセプター刺激薬
AU7823894A (en)	1993-08-27	1995-03-21	Vrije Universiteit	New imidazole derivatives having agonistic or antagonistic activity on the histamine h3 receptor
GB9319534D0 (en) *	1993-09-22	1993-11-10	Boots Co Plc	Therapeutic agents
NZ276883A (en)	1993-11-15	1998-08-26	Schering Corp	1h-imidazol-4-yl)alkyl]benzene derivatives
GB9411045D0 (en) *	1994-06-02	1994-07-20	Smithkline Beecham Plc	Compounds and use
FR2732017B1 (fr)	1995-03-21	2000-09-22	Inst Nat Sante Rech Med	Nouveaux derives de l'imidazole antagonistes et/ou agonistes du recepteur h3 de l'histamine, leur preparation et leurs applications therapeutiques
US5652258A (en)	1995-05-30	1997-07-29	Gliatech, Inc.	2-(4-imidazoyl) cyclopropyl derivatives
CA2222099A1 (en)	1995-05-30	1996-12-05	Gliatech, Inc.	1h-4(5)-substituted imidazole derivatives
CA2222652A1 (en)	1995-06-07	1996-12-19	Gliatech, Inc.	1h-4(5)-substituted imidazole derivatives
EP0882023B1 (en)	1996-02-09	2003-06-04	James Black Foundation Limited	Histamine h 3 receptor ligands
JP3925579B2 (ja) *	1998-02-03	2007-06-06	日本精工株式会社	潤滑剤供給体、並びに前記潤滑剤供給体を備える転がり軸受、リニアガイド装置及びボールねじ装置
EP0982300A3 (en) *	1998-07-29	2000-03-08	Societe Civile Bioprojet	Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications
US6136559A (en) *	1998-10-07	2000-10-24	Ortho Pharmaceutical Corporation	DNA encoding as human histamine receptor of the H3 subtype
PL196773B1 (pl)	1999-06-11	2008-01-31	Toyama Chemical Co Ltd	Pochodna N-alkiloksyalkilo-N,N-dialkiloaminy lub jej sole oraz środek zawierający ten związek stosowany do leczenia chorób neurodegeneratywnych
GB9924941D0 (en)	1999-10-22	1999-12-22	Univ Manchester	Treatment of dyskinesia
US6620839B2 (en) *	2000-07-13	2003-09-16	Abbott Laboratories	1,3-disubstituted and 1,3,3-trisubstituted pyrrolidines as histamine-3 receptor ligands and their therapeutic applications
CA2418369A1 (en)	2000-08-08	2002-02-14	Richard Apodaca	Non-imidazole aryloxyalkylamines as h3 receptor ligands
EP1313470A4 (en)	2000-08-17	2005-02-16	Gliatech Inc	NEW ALICYCLIC IMIDAZOLE AS H 3 ACTIVE SUBSTANCES
EP1320364A1 (en) *	2000-08-21	2003-06-25	Gliatech, Inc.	The use of histamine h3-receptor inverse agonists for the control of appetite and treatment of obesity
PT1373218E (pt) *	2001-03-29	2008-02-21	Ortho Mcneil Janssen Pharm	Derivados de imidazolilo úteis como ligandos do receptor h3 de histamina
WO2003044059A1 (en) *	2001-11-15	2003-05-30	Ortho-Mcneil Pharmaceutical, Inc.	Agonists of recombinant human histamine h3 receptor
WO2003050099A1 (en) *	2001-12-10	2003-06-19	Ortho-Mcneil Pharmaceutical, Inc.	Phenylalkynes
US7279491B2 (en)	2002-10-23	2007-10-09	Janssen Pharmaceutica N.V.	Phenylpiperidines and phenylpyrrolidines
US7595316B2 (en)	2003-06-27	2009-09-29	Banyu Pharmaceutical Co., Ltd.	Heteroaryloxy nitrogenous saturated heterocyclic derivative
FR2856596B1 (fr)	2003-06-27	2007-04-27	Bioprojet Soc Civ	Nouvelle association medicamenteuse psychiatrique et utilisation d'une antagoniste ou agoniste inverse du recepteur h3 de l'histamine pour preparer un medicament prevenant des effets indesirables de psychotropes.
SE0302116D0 (sv) *	2003-07-21	2003-07-21	Astrazeneca Ab	Novel compounds
WO2005028438A1 (ja) *	2003-09-22	2005-03-31	Banyu Pharmaceutical Co., Ltd.	新規ピペリジン誘導体

2005
- 2005-04-01 EP EP05290727A patent/EP1707203A1/en not_active Withdrawn
2006
- 2006-03-29 AU AU2006228413A patent/AU2006228413C1/en not_active Expired
- 2006-03-30 PT PT67444661T patent/PT1863487E/pt unknown
- 2006-03-30 US US11/909,778 patent/US8486947B2/en active Active
- 2006-03-30 JP JP2008503613A patent/JP5546761B2/ja not_active Expired - Lifetime
- 2006-03-30 NZ NZ561940A patent/NZ561940A/en unknown
- 2006-03-30 SG SG200807447-8A patent/SG147415A1/en unknown
- 2006-03-30 MX MX2007012162A patent/MX2007012162A/es active IP Right Grant
- 2006-03-30 EA EA200702135A patent/EA016007B1/ru not_active IP Right Cessation
- 2006-03-30 CN CN2006800157656A patent/CN101171009B/zh not_active Expired - Lifetime
- 2006-03-30 DK DK06744466.1T patent/DK1863487T4/da active
- 2006-03-30 WO PCT/IB2006/000739 patent/WO2006103546A2/en not_active Ceased
- 2006-03-30 RS RS20130359 patent/RS52911B2/sr unknown
- 2006-03-30 SI SI200631636T patent/SI1863487T2/sl unknown
- 2006-03-30 HR HRP20130748T patent/HRP20130748T4/hr unknown
- 2006-03-30 ES ES06744466T patent/ES2426008T5/es not_active Expired - Lifetime
- 2006-03-30 CA CA2603656A patent/CA2603656C/en not_active Expired - Lifetime
- 2006-03-30 UA UAA200710712A patent/UA94902C2/ru unknown
- 2006-03-30 EP EP06744466.1A patent/EP1863487B2/en not_active Expired - Lifetime
- 2006-03-30 ME MEP-2013-98A patent/ME01713B/me unknown
- 2006-03-30 KR KR1020077025126A patent/KR101308527B1/ko not_active Expired - Lifetime
- 2006-03-30 BR BRPI0612216-7A patent/BRPI0612216B1/pt active IP Right Grant
- 2006-03-30 PL PL06744466T patent/PL1863487T5/pl unknown
2007
- 2007-09-20 ZA ZA200708086A patent/ZA200708086B/xx unknown
- 2007-09-26 TN TNP2007000365A patent/TNSN07365A1/fr unknown
- 2007-09-27 MA MA30254A patent/MA29353B1/fr unknown
- 2007-10-09 NO NO20075086A patent/NO343603B1/no unknown
2013
- 2013-08-14 CY CY20131100705T patent/CY1114636T1/el unknown
2014
- 2014-01-06 JP JP2014000383A patent/JP5955872B2/ja not_active Expired - Lifetime
2016
- 2016-03-09 JP JP2016045424A patent/JP2016106142A/ja active Pending

Also Published As

Publication number	Publication date
CA2603656A1 (en)	2006-10-05
AU2006228413C1 (en)	2012-02-02
WO2006103546A3 (en)	2007-03-01
EA016007B1 (ru)	2012-01-30
PL1863487T3 (pl)	2014-10-31
MA29353B1 (fr)	2008-03-03
BRPI0612216A2 (pt)	2010-10-26
WO2006103546A2 (en)	2006-10-05
MX2007012162A (es)	2007-11-22
PT1863487E (pt)	2013-08-29
NO20075086L (no)	2007-12-27
ME01713B (me)	2014-09-20
KR101308527B1 (ko)	2013-09-17
JP5955872B2 (ja)	2016-07-20
ES2426008T3 (es)	2013-10-18
NZ561940A (en)	2010-06-25
CY1114636T1 (el)	2016-10-05
RS52911B2 (sr)	2019-11-29
ES2426008T5 (es)	2020-03-20
CN101171009A (zh)	2008-04-30
ZA200708086B (en)	2008-10-29
HRP20130748T4 (hr)	2019-11-15
CN101171009B (zh)	2012-11-07
SG147415A1 (en)	2008-11-28
TNSN07365A1 (fr)	2008-12-31
UA94902C2 (ru)	2011-06-25
US8486947B2 (en)	2013-07-16
HRP20130748T1 (en)	2013-10-11
EP1863487B1 (en)	2013-05-29
SI1863487T1 (sl)	2013-09-30
RS52911B (sr)	2014-02-28
JP2016106142A (ja)	2016-06-16
AU2006228413A1 (en)	2006-10-05
SI1863487T2 (sl)	2019-11-29
BRPI0612216B1 (pt)	2022-04-19
US20090318433A1 (en)	2009-12-24
JP2014062126A (ja)	2014-04-10
DK1863487T4 (da)	2019-10-14
KR20080002904A (ko)	2008-01-04
EP1707203A1 (en)	2006-10-04
EP1863487A2 (en)	2007-12-12
JP5546761B2 (ja)	2014-07-09
NO343603B1 (no)	2019-04-08
CA2603656C (en)	2015-06-16
EP1863487B2 (en)	2019-07-17
JP2008534572A (ja)	2008-08-28
DK1863487T3 (da)	2013-08-12
AU2006228413B2 (en)	2011-09-15
EA200702135A1 (ru)	2008-04-28

Publication	Publication Date	Title
ME01713B (me)	2014-09-20	Liječenje simptoma parkinsonove bolesti sa alkilamin histaminom bez imidazola-h3 receptora uganda
SI1877096T1 (sl)	2014-08-29	Terapija ledvičnih kamnov brez litotripsije
GB0506835D0 (en)	2005-05-11	Therapeutic use of nefopam
GB0516068D0 (en)	2005-09-14	Well treatment
EP1768656A4 (en)	2008-01-23	TREATMENT OF OCULAR DISEASES
GB2430002B (en)	2009-06-03	Well treatment
DE602006000763D1 (de)	2008-05-08	Kissenkörper
GB0507003D0 (en)	2005-05-11	Therapeutic
GB0424085D0 (en)	2004-12-01	Well treatment
GB2422769B (en)	2010-05-19	Heat therapy garment
GB0501655D0 (en)	2005-03-02	Therapeutic use
GB0410101D0 (en)	2004-06-09	Parkinson's disease
GB0502171D0 (en)	2005-03-09	Well treatment
GB0515703D0 (en)	2005-09-07	Therapeutic use of nefopam
ZA200709075B (en)	2008-10-29	Novel histamine H3-receptor ligands and their therapeutic applications
SG126063A1 (en)	2006-10-30	Methods for the treatment of insulin resistance and disease states characterized by insulin resistance
AU305258S (en)	2006-02-01	Upper body garment
AU305256S (en)	2006-02-01	Upper body garment
AU305257S (en)	2006-02-01	Upper body garment
AU302683S (en)	2005-08-10	Upper body garment
AU305259S (en)	2006-02-01	Upper body garment
AU305253S (en)	2006-02-01	Upper body garment
AU305255S (en)	2006-02-01	Upper body garment
AU305254S (en)	2006-02-01	Upper body garment
GB0517025D0 (en)	2005-09-28	Sexual stimulator