PL1909792T3 - Podstawione pochodne piperydyny jako antagonisty receptora somatostatyny SST1 - Google Patents
Podstawione pochodne piperydyny jako antagonisty receptora somatostatyny SST1Info
- Publication number
- PL1909792T3 PL1909792T3 PL06762563T PL06762563T PL1909792T3 PL 1909792 T3 PL1909792 T3 PL 1909792T3 PL 06762563 T PL06762563 T PL 06762563T PL 06762563 T PL06762563 T PL 06762563T PL 1909792 T3 PL1909792 T3 PL 1909792T3
- Authority
- PL
- Poland
- Prior art keywords
- receptor antagonists
- substituted piperidine
- piperidine derivatives
- sst1 receptor
- somatostatin
- Prior art date
Links
- 102000005157 Somatostatin Human genes 0.000 title abstract 2
- 108010056088 Somatostatin Proteins 0.000 title abstract 2
- 239000002464 receptor antagonist Substances 0.000 title abstract 2
- 229940044551 receptor antagonist Drugs 0.000 title abstract 2
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title abstract 2
- 229960000553 somatostatin Drugs 0.000 title abstract 2
- 101150029725 sst1 gene Proteins 0.000 title abstract 2
- 150000003053 piperidines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0514615.4A GB0514615D0 (en) | 2005-07-15 | 2005-07-15 | Organic compounds |
| EP06762563A EP1909792B1 (en) | 2005-07-15 | 2006-07-13 | Substituted piperidine derivatives as somatostatin sst1 receptor antagonists |
| PCT/EP2006/006867 WO2007009662A1 (en) | 2005-07-15 | 2006-07-13 | Substituted piperidine derivatives as somatostatin sst1 receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1909792T3 true PL1909792T3 (pl) | 2010-02-26 |
Family
ID=34897328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06762563T PL1909792T3 (pl) | 2005-07-15 | 2006-07-13 | Podstawione pochodne piperydyny jako antagonisty receptora somatostatyny SST1 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7754719B2 (pl) |
| EP (1) | EP1909792B1 (pl) |
| JP (1) | JP2009501180A (pl) |
| KR (1) | KR20080025731A (pl) |
| CN (1) | CN101222924A (pl) |
| AT (1) | ATE441415T1 (pl) |
| AU (1) | AU2006272049A1 (pl) |
| BR (1) | BRPI0612994A2 (pl) |
| CA (1) | CA2615236A1 (pl) |
| DE (1) | DE602006008957D1 (pl) |
| ES (1) | ES2333165T3 (pl) |
| GB (1) | GB0514615D0 (pl) |
| MX (1) | MX2008000709A (pl) |
| PL (1) | PL1909792T3 (pl) |
| PT (1) | PT1909792E (pl) |
| RU (1) | RU2008105362A (pl) |
| WO (1) | WO2007009662A1 (pl) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5149817A (en) | 1990-03-05 | 1992-09-22 | Shionogi & Co., Ltd. | Teirahydropyridine derivatives |
| JP2001502712A (ja) * | 1996-10-31 | 2001-02-27 | ノボ ノルディスク アクティーゼルスカブ | 束縛されたソマトスタチン・アゴニスト及びアンタゴニスト |
| EP1086947A1 (en) | 1999-09-01 | 2001-03-28 | Pfizer Products Inc. | Somatostatin antagonists and agonists that act at the SST subtype 2 receptor |
| US7115741B2 (en) | 2001-09-06 | 2006-10-03 | Levy Daniel E | 4-thieno[2,3-D]pyrimidin-4-YL piperazine compounds |
| GB0127008D0 (en) | 2001-11-09 | 2002-01-02 | Novartis Ag | Organic compounds |
| JPWO2004011430A1 (ja) * | 2002-07-25 | 2005-11-24 | アステラス製薬株式会社 | ナトリウムチャネル阻害剤 |
-
2005
- 2005-07-15 GB GBGB0514615.4A patent/GB0514615D0/en not_active Ceased
-
2006
- 2006-07-13 PT PT06762563T patent/PT1909792E/pt unknown
- 2006-07-13 CA CA002615236A patent/CA2615236A1/en not_active Abandoned
- 2006-07-13 DE DE602006008957T patent/DE602006008957D1/de active Active
- 2006-07-13 CN CNA2006800259166A patent/CN101222924A/zh active Pending
- 2006-07-13 JP JP2008520800A patent/JP2009501180A/ja active Pending
- 2006-07-13 KR KR1020087001023A patent/KR20080025731A/ko not_active Withdrawn
- 2006-07-13 ES ES06762563T patent/ES2333165T3/es active Active
- 2006-07-13 MX MX2008000709A patent/MX2008000709A/es not_active Application Discontinuation
- 2006-07-13 AU AU2006272049A patent/AU2006272049A1/en not_active Abandoned
- 2006-07-13 PL PL06762563T patent/PL1909792T3/pl unknown
- 2006-07-13 WO PCT/EP2006/006867 patent/WO2007009662A1/en not_active Ceased
- 2006-07-13 BR BRPI0612994-3A patent/BRPI0612994A2/pt not_active IP Right Cessation
- 2006-07-13 AT AT06762563T patent/ATE441415T1/de active
- 2006-07-13 EP EP06762563A patent/EP1909792B1/en active Active
- 2006-07-13 US US11/995,725 patent/US7754719B2/en not_active Expired - Fee Related
- 2006-07-13 RU RU2008105362/04A patent/RU2008105362A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20080255142A1 (en) | 2008-10-16 |
| JP2009501180A (ja) | 2009-01-15 |
| ATE441415T1 (de) | 2009-09-15 |
| KR20080025731A (ko) | 2008-03-21 |
| RU2008105362A (ru) | 2009-08-20 |
| EP1909792A1 (en) | 2008-04-16 |
| ES2333165T3 (es) | 2010-02-17 |
| US7754719B2 (en) | 2010-07-13 |
| BRPI0612994A2 (pt) | 2010-12-14 |
| EP1909792B1 (en) | 2009-09-02 |
| DE602006008957D1 (de) | 2009-10-15 |
| CN101222924A (zh) | 2008-07-16 |
| MX2008000709A (es) | 2008-03-18 |
| WO2007009662A1 (en) | 2007-01-25 |
| CA2615236A1 (en) | 2007-01-25 |
| GB0514615D0 (en) | 2005-08-24 |
| PT1909792E (pt) | 2009-12-09 |
| AU2006272049A1 (en) | 2007-01-25 |
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