PL194251B1 - Sposób konwersji pochodnych kwasu treo-(2R,3R)-2-hydroksy-3-(2-aminofenylotio)-3-(4-metoksyfenylo)propionowego - Google Patents

Sposób konwersji pochodnych kwasu treo-(2R,3R)-2-hydroksy-3-(2-aminofenylotio)-3-(4-metoksyfenylo)propionowego

Info

Publication number
PL194251B1
PL194251B1 PL98339054A PL33905498A PL194251B1 PL 194251 B1 PL194251 B1 PL 194251B1 PL 98339054 A PL98339054 A PL 98339054A PL 33905498 A PL33905498 A PL 33905498A PL 194251 B1 PL194251 B1 PL 194251B1
Authority
PL
Poland
Prior art keywords
compound
formula
iii
acid
methoxyphenyl
Prior art date
Application number
PL98339054A
Other languages
English (en)
Polish (pl)
Other versions
PL339054A1 (en
Inventor
Pietro Allegrini
Gaetano Marchioro
Giuseppe Barreca
Marco Villa
Laura Russo
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of PL339054A1 publication Critical patent/PL339054A1/xx
Publication of PL194251B1 publication Critical patent/PL194251B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL98339054A 1997-10-22 1998-10-12 Sposób konwersji pochodnych kwasu treo-(2R,3R)-2-hydroksy-3-(2-aminofenylotio)-3-(4-metoksyfenylo)propionowego PL194251B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97MI002374A IT1295376B1 (it) 1997-10-22 1997-10-22 Processo per il riciclo di un sottoprodotto della sintesi del diltiazem
PCT/EP1998/006467 WO1999020603A1 (fr) 1997-10-22 1998-10-12 Technique de reutilisation de produit de rebut de la synthese du diltiazem

Publications (2)

Publication Number Publication Date
PL339054A1 PL339054A1 (en) 2000-12-04
PL194251B1 true PL194251B1 (pl) 2007-05-31

Family

ID=11378079

Family Applications (1)

Application Number Title Priority Date Filing Date
PL98339054A PL194251B1 (pl) 1997-10-22 1998-10-12 Sposób konwersji pochodnych kwasu treo-(2R,3R)-2-hydroksy-3-(2-aminofenylotio)-3-(4-metoksyfenylo)propionowego

Country Status (17)

Country Link
US (1) US6114523A (fr)
EP (1) EP1025080B1 (fr)
JP (1) JP2001520219A (fr)
KR (1) KR20010031267A (fr)
CN (1) CN1121383C (fr)
AT (1) ATE230724T1 (fr)
AU (1) AU743612B2 (fr)
CA (1) CA2304371A1 (fr)
DE (1) DE69810653T2 (fr)
ES (1) ES2189263T3 (fr)
HU (1) HU225099B1 (fr)
IL (1) IL134534A0 (fr)
IT (1) IT1295376B1 (fr)
PL (1) PL194251B1 (fr)
SK (1) SK284417B6 (fr)
WO (1) WO1999020603A1 (fr)
ZA (1) ZA989559B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1512677A4 (fr) * 2002-06-11 2007-06-20 Kaneka Corp Procede de production d'un $g(b)-aminoalcool optiquement actif
CN103755663B (zh) * 2014-01-26 2016-02-24 武汉工程大学 地尔硫卓中间体副产物L-cis-内酰胺的回收工艺
CN110284181A (zh) * 2019-08-07 2019-09-27 山东新华制药股份有限公司 地尔硫卓ab异构体的单晶制备方法
CN112279820B (zh) * 2020-12-18 2021-04-02 苏州开元民生科技股份有限公司 2-(4-甲氧苯基)-3-羟基-2,3-二氢-1,5-苯并硫氮杂卓酮的制备方法
CN118684635B (zh) * 2024-08-22 2024-11-05 苏州开元民生科技股份有限公司 一种地尔硫卓手性中间体的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1236467A (en) * 1967-10-28 1971-06-23 Tanabe Seiyaku Co Benzothiazepine derivatives
DE3263466D1 (en) * 1981-02-27 1985-06-20 Tanabe Seiyaku Co Novel process for preparing threo-2-hydroxy-3-(4-methoxyphenyl)-3-(2-nitrophenylthio)-propionic ester
SE449611B (sv) * 1982-07-09 1987-05-11 Tanabe Seiyaku Co Sett att framstella 1,5-bensotiazepinderivat
IT1152721B (it) * 1982-10-15 1987-01-07 Luso Farmaco Inst Risoluzione ottica dell'acido dl-alfa-2-idrossi-3-(4-metossifenil)-3-(2-amminofeniltio)propionico
IT1230057B (it) * 1989-04-13 1991-09-27 Zambon Spa Processo di risoluzione di intermedi utili per la preparazione di 1,5-benzotiazepine
JPH0798813B2 (ja) * 1989-04-28 1995-10-25 田辺製薬株式会社 １，５―ベンゾチアゼピン誘導体の製法
IT1232306B (it) * 1989-07-27 1992-01-28 Zambon Spa Processo di risoluzione di intermedi utili per la preparazione del diltiazem
IT1237526B (it) * 1989-12-06 1993-06-08 Zambon Spa Processo di preparazione di un intermedio per il diltiazem
JPH085869B2 (ja) * 1990-03-08 1996-01-24 田辺製薬株式会社 １，５−ベンゾチアゼピン誘導体の製法
NL9000763A (nl) * 1990-03-31 1991-10-16 Stamicarbon Werkwijze voor het bereiden van 1,5-benzothiazepine-derivaten.
IT1249318B (it) * 1991-05-23 1995-02-22 Zambon Spa Processo per la preparazione di benzotiazepine per ciclizzazione con acidi fosfonici
FI93741C (fi) * 1993-03-24 1995-05-26 Orion Yhtymae Oy Menetelmä optisesti puhtaitten (2S,3S)- ja (2R,3R)-threo-alkyyli-2-hydroksi-3-(4-metoksifenyyli)-3-(2-X-fenyylitio)propionaattien tai vastaavien asyloitujen yhdisteiden valmistamiseksi
JPH07108982A (ja) * 1993-10-13 1995-04-25 Nippon Shokubai Co Ltd 浮き桟橋

Also Published As

Publication number Publication date
SK284417B6 (sk) 2005-03-04
HUP0100997A3 (en) 2002-11-28
ZA989559B (en) 1999-04-22
SK5602000A3 (en) 2000-09-12
KR20010031267A (ko) 2001-04-16
IL134534A0 (en) 2001-04-30
DE69810653D1 (de) 2003-02-13
US6114523A (en) 2000-09-05
AU1153199A (en) 1999-05-10
JP2001520219A (ja) 2001-10-30
ES2189263T3 (es) 2003-07-01
ATE230724T1 (de) 2003-01-15
CN1121383C (zh) 2003-09-17
PL339054A1 (en) 2000-12-04
EP1025080A1 (fr) 2000-08-09
AU743612B2 (en) 2002-01-31
WO1999020603A1 (fr) 1999-04-29
EP1025080B1 (fr) 2003-01-08
HUP0100997A2 (hu) 2001-08-28
ITMI972374A1 (it) 1999-04-22
IT1295376B1 (it) 1999-05-12
CA2304371A1 (fr) 1999-04-29
CN1271340A (zh) 2000-10-25
HU225099B1 (en) 2006-06-28
DE69810653T2 (de) 2003-11-13

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Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20121012