PL2018388T3 - Związki bis-adenozyny jako agoniści receptora A2A adenozyny - Google Patents

Związki bis-adenozyny jako agoniści receptora A2A adenozyny

Info

Publication number
PL2018388T3
PL2018388T3 PL07724376T PL07724376T PL2018388T3 PL 2018388 T3 PL2018388 T3 PL 2018388T3 PL 07724376 T PL07724376 T PL 07724376T PL 07724376 T PL07724376 T PL 07724376T PL 2018388 T3 PL2018388 T3 PL 2018388T3
Authority
PL
Poland
Prior art keywords
bisadenosine
adenosine
compounds
receptor agonists
agonists
Prior art date
Application number
PL07724376T
Other languages
English (en)
Inventor
Robin Alec Fairhurst
Roger John Taylor
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2018388T3 publication Critical patent/PL2018388T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL07724376T 2006-04-21 2007-04-19 Związki bis-adenozyny jako agoniści receptora A2A adenozyny PL2018388T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0607950.3A GB0607950D0 (en) 2006-04-21 2006-04-21 Organic compounds
PCT/EP2007/003439 WO2007121924A2 (en) 2006-04-21 2007-04-19 Bisadenosine compounds as adenosine a2a receptor agonists
EP07724376A EP2018388B9 (en) 2006-04-21 2007-04-19 Bisadenosine compounds as adenosine a2a receptor agonists

Publications (1)

Publication Number Publication Date
PL2018388T3 true PL2018388T3 (pl) 2011-08-31

Family

ID=36581047

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07724376T PL2018388T3 (pl) 2006-04-21 2007-04-19 Związki bis-adenozyny jako agoniści receptora A2A adenozyny

Country Status (32)

Country Link
US (1) US8193164B2 (pl)
EP (1) EP2018388B9 (pl)
JP (1) JP2009534341A (pl)
KR (1) KR20080112399A (pl)
CN (1) CN101437829B (pl)
AR (1) AR060606A1 (pl)
AT (1) ATE502040T1 (pl)
AU (1) AU2007241347A1 (pl)
CA (1) CA2648037A1 (pl)
CL (1) CL2007001132A1 (pl)
CR (1) CR10328A (pl)
CY (1) CY1111568T1 (pl)
DE (1) DE602007013203D1 (pl)
DK (1) DK2018388T3 (pl)
EC (1) ECSP088837A (pl)
ES (1) ES2363255T3 (pl)
GB (1) GB0607950D0 (pl)
GT (1) GT200800218A (pl)
HR (1) HRP20110445T1 (pl)
IL (1) IL194398A0 (pl)
MA (1) MA30404B1 (pl)
MX (1) MX2008013398A (pl)
NO (1) NO20084456L (pl)
PE (1) PE20071228A1 (pl)
PL (1) PL2018388T3 (pl)
PT (1) PT2018388E (pl)
RU (1) RU2008145715A (pl)
SI (1) SI2018388T1 (pl)
TN (1) TNSN08409A1 (pl)
TW (1) TW200813074A (pl)
WO (1) WO2007121924A2 (pl)
ZA (1) ZA200808103B (pl)

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GB0607944D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
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US20090181934A1 (en) * 2007-10-17 2009-07-16 Novartis Ag Organic Compounds
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Also Published As

Publication number Publication date
EP2018388B1 (en) 2011-03-16
NO20084456L (no) 2008-12-09
GB0607950D0 (en) 2006-05-31
HRP20110445T1 (hr) 2011-07-31
PT2018388E (pt) 2011-06-27
TW200813074A (en) 2008-03-16
AU2007241347A1 (en) 2007-11-01
CN101437829B (zh) 2012-03-21
MX2008013398A (es) 2008-11-04
KR20080112399A (ko) 2008-12-24
MA30404B1 (fr) 2009-05-04
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PE20071228A1 (es) 2008-01-24
US20100190784A1 (en) 2010-07-29
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CR10328A (es) 2008-11-18
TNSN08409A1 (en) 2010-04-14
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JP2009534341A (ja) 2009-09-24
ZA200808103B (en) 2009-07-29
IL194398A0 (en) 2009-08-03
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ATE502040T1 (de) 2011-04-15
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CL2007001132A1 (es) 2008-05-23
GT200800218A (es) 2008-12-15
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CN101437829A (zh) 2009-05-20
EP2018388A2 (en) 2009-01-28

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