PL2051962T3 - Pochodne kwasu (3-amino-1,2,3,4-tetrahydro-9h-karbazol-9-ilo)-octowego - Google Patents

Pochodne kwasu (3-amino-1,2,3,4-tetrahydro-9h-karbazol-9-ilo)-octowego

Info

Publication number: PL2051962T3
Authority: PL; Poland
Prior art keywords: carbazol; tetrahydro; amino; acetic acid; acid derivatives
Prior art date: 2006-08-07

Application number

PL07805287T

Other languages

English (en)

Inventor

Heinz Fretz

Julien Pothier

Philippe Risch

Original Assignee

Actelion Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-08-07

Filing date

2007-08-02

Publication date

2012-03-30

2007-08-02 Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd

2012-03-30 Publication of PL2051962T3 publication Critical patent/PL2051962T3/pl

Links

CVQXAMOXLNWPLS-UHFFFAOYSA-N 2-(3-amino-1,2,3,4-tetrahydrocarbazol-9-yl)acetic acid Chemical class C12=CC=CC=C2N(CC(O)=O)C2=C1CC(N)CC2 CVQXAMOXLNWPLS-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Cardiology (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Heart & Thoracic Surgery (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Hematology (AREA)
Otolaryngology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PL07805287T 2006-08-07 2007-08-02 Pochodne kwasu (3-amino-1,2,3,4-tetrahydro-9h-karbazol-9-ilo)-octowego PL2051962T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IB2006052723		2006-08-07
PCT/IB2007/053046 WO2008017989A1 (en)	2006-08-07	2007-08-02	(3-amino-1,2,3,4-tetrahydro-9h-carbazol-9-yl)-acetic acid derivatives
EP07805287A EP2051962B1 (en)	2006-08-07	2007-08-02	(3-amino-1,2,3,4-tetrahydro-9h-carbazol-9-yl)-acetic acid derivatives

Publications (1)

Publication Number	Publication Date
PL2051962T3 true PL2051962T3 (pl)	2012-03-30

Family

ID=38805811

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL07805287T PL2051962T3 (pl)	2006-08-07	2007-08-02	Pochodne kwasu (3-amino-1,2,3,4-tetrahydro-9h-karbazol-9-ilo)-octowego

Country Status (27)

Country	Link
US (1)	US8143304B2 (pl)
EP (2)	EP2316824A1 (pl)
JP (1)	JP5220013B2 (pl)
KR (1)	KR101411820B1 (pl)
CN (1)	CN101500996B (pl)
AR (1)	AR062222A1 (pl)
AT (1)	ATE530523T1 (pl)
AU (1)	AU2007282949B8 (pl)
BR (1)	BRPI0715179A2 (pl)
CA (1)	CA2658986C (pl)
CL (1)	CL2007002274A1 (pl)
CY (1)	CY1112276T1 (pl)
DK (1)	DK2051962T3 (pl)
ES (1)	ES2374321T3 (pl)
HR (1)	HRP20120044T1 (pl)
IL (1)	IL196891A (pl)
MA (1)	MA30696B1 (pl)
MX (1)	MX2009001105A (pl)
MY (1)	MY147588A (pl)
NO (1)	NO20090979L (pl)
NZ (1)	NZ574705A (pl)
PL (1)	PL2051962T3 (pl)
PT (1)	PT2051962E (pl)
RU (1)	RU2448092C2 (pl)
SI (1)	SI2051962T1 (pl)
TW (1)	TWI408126B (pl)
WO (1)	WO2008017989A1 (pl)

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BRPI0907364A2 (pt)	2008-02-01	2015-07-14	Amira Pharmaceuticals Inc	Antagonistas aminoalquilbifenil n,n-disubstituídos de receptores d2 de prostaglandina
JP2011513242A (ja)	2008-02-25	2011-04-28	アミラファーマシューティカルズ，インク．	プロスタグランジンｄ２受容体アンタゴニスト
WO2010008864A2 (en)	2008-06-24	2010-01-21	Amira Pharmaceuticals, Inc.	Cycloalkane[b]indole angtagonists of prostaglandin d2 receptors
GB2463788B (en)	2008-09-29	2010-12-15	Amira Pharmaceuticals Inc	Heteroaryl antagonists of prostaglandin D2 receptors
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AR080703A1 (es) *	2010-03-22	2012-05-02	Actelion Pharmaceuticals Ltd	Derivados de 3-(heteroaril-amino)-1,2,3,4-tetrahidro-9h-carbazol, moduladores de receptores de prostaglandina d2, composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento de trastornos alergicos o inmunitarios tales como asma.
EP2457900A1 (en)	2010-11-25	2012-05-30	Almirall, S.A.	New pyrazole derivatives having CRTh2 antagonistic behaviour
DK2697223T3 (en)	2011-04-14	2016-09-05	Actelion Pharmaceuticals Ltd	7- (heteroaryl-amino) -6,7,8,9-tetrahydro-pyrido [1,2-a] indole-acetic acid derivatives and their use as prostaglandin D2 receptor
PE20161177A1 (es)	2014-03-17	2016-11-18	Actelion Pharmaceuticals Ltd	Derivados del acido acetico azaindol y su uso como moduladores del receptor de prostaglandina d2
WO2015140701A1 (en)	2014-03-18	2015-09-24	Actelion Pharmaceuticals Ltd	Azaindole acetic acid derivatives and their use as prostaglandin d2 receptor modulators
CN104402798B (zh) *	2014-10-21	2016-09-14	杭州瑞德化工有限公司	一种3-氨基-1，2，3，4-四氢咔唑的拆分方法
WO2016133793A1 (en)	2015-02-16	2016-08-25	Merck Sharp & Dohme Corp.	FACTOR IXa INHIBITORS
KR20180053345A (ko)	2015-09-15	2018-05-21	이도르시아 파마슈티컬스 리미티드	결정질 형태
CN112094223B (zh) *	2019-06-18	2023-09-15	华东师范大学	一类脲基四氢咔唑类小分子有机化合物及用途

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2007
- 2007-08-02 AT AT07805287T patent/ATE530523T1/de active
- 2007-08-02 BR BRPI0715179-9A patent/BRPI0715179A2/pt not_active IP Right Cessation
- 2007-08-02 NZ NZ574705A patent/NZ574705A/en not_active IP Right Cessation
- 2007-08-02 MX MX2009001105A patent/MX2009001105A/es active IP Right Grant
- 2007-08-02 EP EP11000641A patent/EP2316824A1/en not_active Withdrawn
- 2007-08-02 HR HR20120044T patent/HRP20120044T1/hr unknown
- 2007-08-02 CN CN2007800292169A patent/CN101500996B/zh not_active Expired - Fee Related
- 2007-08-02 DK DK07805287.5T patent/DK2051962T3/da active
- 2007-08-02 EP EP07805287A patent/EP2051962B1/en not_active Not-in-force
- 2007-08-02 CA CA2658986A patent/CA2658986C/en not_active Expired - Fee Related
- 2007-08-02 SI SI200730818T patent/SI2051962T1/sl unknown
- 2007-08-02 WO PCT/IB2007/053046 patent/WO2008017989A1/en not_active Ceased
- 2007-08-02 RU RU2009107889/04A patent/RU2448092C2/ru not_active IP Right Cessation
- 2007-08-02 ES ES07805287T patent/ES2374321T3/es active Active
- 2007-08-02 AU AU2007282949A patent/AU2007282949B8/en not_active Ceased
- 2007-08-02 KR KR1020097004370A patent/KR101411820B1/ko not_active Expired - Fee Related
- 2007-08-02 MY MYPI20090462A patent/MY147588A/en unknown
- 2007-08-02 PT PT07805287T patent/PT2051962E/pt unknown
- 2007-08-02 JP JP2009523396A patent/JP5220013B2/ja not_active Expired - Fee Related
- 2007-08-02 PL PL07805287T patent/PL2051962T3/pl unknown
- 2007-08-02 US US12/376,932 patent/US8143304B2/en not_active Expired - Fee Related
- 2007-08-06 TW TW096128871A patent/TWI408126B/zh not_active IP Right Cessation
- 2007-08-06 AR ARP070103462A patent/AR062222A1/es unknown
- 2007-08-06 CL CL200702274A patent/CL2007002274A1/es unknown
2009
- 2009-02-04 IL IL196891A patent/IL196891A/en not_active IP Right Cessation
- 2009-02-17 MA MA31646A patent/MA30696B1/fr unknown
- 2009-03-04 NO NO20090979A patent/NO20090979L/no not_active Application Discontinuation
2012
- 2012-01-25 CY CY20121100090T patent/CY1112276T1/el unknown

Also Published As

Publication number	Publication date
AR062222A1 (es)	2008-10-22
CN101500996A (zh)	2009-08-05
AU2007282949B2 (en)	2012-08-30
MY147588A (en)	2012-12-31
IL196891A0 (en)	2009-11-18
CY1112276T1 (el)	2015-12-09
EP2051962A1 (en)	2009-04-29
MX2009001105A (es)	2009-02-10
AU2007282949B8 (en)	2012-10-04
CL2007002274A1 (es)	2008-04-18
WO2008017989A1 (en)	2008-02-14
HRP20120044T1 (hr)	2012-02-29
TW200817328A (en)	2008-04-16
IL196891A (en)	2013-07-31
US20100190830A1 (en)	2010-07-29
RU2009107889A (ru)	2010-09-20
EP2316824A1 (en)	2011-05-04
JP5220013B2 (ja)	2013-06-26
CA2658986A1 (en)	2008-02-14
JP2010500337A (ja)	2010-01-07
PT2051962E (pt)	2012-01-10
NO20090979L (no)	2009-05-06
MA30696B1 (fr)	2009-09-01
CA2658986C (en)	2014-11-25
DK2051962T3 (da)	2012-01-02
HK1130062A1 (en)	2009-12-18
ATE530523T1 (de)	2011-11-15
US8143304B2 (en)	2012-03-27
RU2448092C2 (ru)	2012-04-20
KR20090047504A (ko)	2009-05-12
AU2007282949A1 (en)	2008-02-14
EP2051962B1 (en)	2011-10-26
CN101500996B (zh)	2012-07-04
NZ574705A (en)	2011-12-22
BRPI0715179A2 (pt)	2013-06-11
TWI408126B (zh)	2013-09-11
SI2051962T1 (sl)	2012-02-29
KR101411820B1 (ko)	2014-06-24
ES2374321T3 (es)	2012-02-15

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GB0703805D0 (en)	2007-04-11	Tyre 80
GB0704769D0 (en)	2007-04-18	Tyre 106