PL2061803T3 - Proces oczyszczania białek zawierających fc - Google Patents

Proces oczyszczania białek zawierających fc

Info

Publication number
PL2061803T3
PL2061803T3 PL07802925T PL07802925T PL2061803T3 PL 2061803 T3 PL2061803 T3 PL 2061803T3 PL 07802925 T PL07802925 T PL 07802925T PL 07802925 T PL07802925 T PL 07802925T PL 2061803 T3 PL2061803 T3 PL 2061803T3
Authority
PL
Poland
Prior art keywords
purification
containing proteins
proteins
Prior art date
Application number
PL07802925T
Other languages
English (en)
Other versions
PL2061803T5 (pl
Inventor
Alex Eon-Duval
Alain Lamproye
Original Assignee
Ares Trading S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38610939&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2061803(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ares Trading S.A. filed Critical Ares Trading S.A.
Publication of PL2061803T3 publication Critical patent/PL2061803T3/pl
Publication of PL2061803T5 publication Critical patent/PL2061803T5/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL07802925.3T 2006-08-28 2007-08-27 Proces oczyszczania białek zawierających fc PL2061803T5 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP06119611 2006-08-28
US84254206P 2006-09-06 2006-09-06
EP07802925.3A EP2061803B2 (en) 2006-08-28 2007-08-27 Process for the purification of fc-containing proteins
PCT/EP2007/058887 WO2008025748A1 (en) 2006-08-28 2007-08-27 Process for the purification of fc-containing proteins

Publications (2)

Publication Number Publication Date
PL2061803T3 true PL2061803T3 (pl) 2020-02-28
PL2061803T5 PL2061803T5 (pl) 2023-03-27

Family

ID=38610939

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07802925.3T PL2061803T5 (pl) 2006-08-28 2007-08-27 Proces oczyszczania białek zawierających fc

Country Status (20)

Country Link
US (1) US8513393B2 (pl)
EP (1) EP2061803B2 (pl)
JP (1) JP2010501623A (pl)
KR (1) KR101770312B1 (pl)
AR (1) AR062570A1 (pl)
AU (1) AU2007291283B2 (pl)
CA (1) CA2661748C (pl)
DK (1) DK2061803T4 (pl)
EA (1) EA017152B1 (pl)
ES (1) ES2755386T5 (pl)
FI (1) FI2061803T4 (pl)
HU (1) HUE045898T2 (pl)
IL (1) IL197220A (pl)
LT (1) LT2061803T (pl)
MX (1) MX2009002014A (pl)
PL (1) PL2061803T5 (pl)
PT (1) PT2061803T (pl)
SI (1) SI2061803T2 (pl)
UA (1) UA99262C2 (pl)
WO (1) WO2008025748A1 (pl)

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JP2010501623A (ja) † 2006-08-28 2010-01-21 アレス トレーディング ソシエテ アノニム Ｆｃ含有タンパク質の精製法
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CN104974251A (zh) * 2008-10-20 2015-10-14 Abbvie公司 在抗体纯化过程中的病毒灭活
CN102257004A (zh) * 2008-10-20 2011-11-23 雅培制药有限公司 与il-12结合的抗体及其纯化方法
CA2739077A1 (en) * 2008-10-20 2010-04-29 Robert K. Hickman Antibodies that bind to il-18 and methods of purifying the same
CA2932207A1 (en) * 2008-10-20 2010-12-09 Abbvie Inc. Isolation and purification of antibodies using protein a affinity chromatography
US8536316B2 (en) * 2009-08-07 2013-09-17 Emd Millipore Corporation Methods for purifying a target protein from one or more impurities in a sample
BR112012014937B1 (pt) 2009-12-18 2021-01-19 Novartis Ag método de produção de um anticorpo, fragmento de anticorpo ou proteína de fusão fc purificada usando uma matriz de cromatografia de afinidade
CA2787009C (en) 2010-01-15 2018-04-03 Bio-Rad Laboratories, Inc. Surface neutralization of apatite
US8895707B2 (en) * 2010-08-18 2014-11-25 Bio-Rad Laboratories, Inc. Elution of proteins from hydroxyapatite resins without resin deterioration
JP5798307B2 (ja) * 2010-09-03 2015-10-21 国立大学法人名古屋大学 グロボトリアオシルセラミドを特異的に認識するモノクローナル抗体及びその作製法
WO2012084829A1 (en) 2010-12-21 2012-06-28 F. Hoffmann-La Roche Ag Isoform enriched antibody preparation and method for obtaining it
JP5881744B2 (ja) 2011-02-02 2016-03-09 バイオ−ラッド ラボラトリーズ インコーポレーティッド アルカリ溶液でのアパタイトの表面中和方法
EP2691411B1 (en) 2011-03-29 2020-02-26 GlaxoSmithKline LLC Buffer system for protein purification
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
US9815695B2 (en) 2012-05-30 2017-11-14 Bio-Rad Laboratories, Inc. In situ restoration of apatite-based chromatography resins
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
WO2015189832A1 (en) * 2014-06-13 2015-12-17 Lupin Limited Process for the purification of tnfr:fc fusion protein
EP3157863B1 (en) 2014-06-23 2023-06-21 Bio-Rad Laboratories, Inc. Apatite in-situ restoration
CN105392569B (zh) 2014-06-23 2019-08-20 生物辐射实验室股份有限公司 磷灰石预处理
EP2975050B1 (en) * 2014-07-18 2019-05-29 Sandoz Ag Quantification of misfolded TNFR2:Fc
CA2959629C (en) * 2014-09-03 2023-10-31 Boehringer Ingelheim International Gmbh Compound targeting il-23a and tnf-alpha and uses thereof
BR112017018365A2 (pt) * 2015-03-13 2018-04-10 Bristol-Myers Squibb Company uso de lavagens alcalinas durante cromatografia para remoção de impurezas
EP3694870A1 (en) 2017-10-10 2020-08-19 Alpine Immune Sciences, Inc. Ctla-4 variant immunomodulatory proteins and uses thereof
US12202882B2 (en) 2020-05-08 2025-01-21 Alpine Immune Sciences, Inc. APRIL and BAFF inhibitory immunomodulatory proteins and methods of use thereof
CN116322775A (zh) 2020-06-02 2023-06-23 阿雷斯贸易股份有限公司 IgA肾病治疗的相关方法

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CA2065346C (en) 1989-09-05 2005-03-29 Craig A. Smith Tumor necrosis factor-.alpha. and-.beta. receptors
US5447851B1 (en) * 1992-04-02 1999-07-06 Univ Texas System Board Of Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells
NZ256293A (en) 1992-09-15 1997-06-24 Immunex Corp Method of treating tumour necrosis factor - mediated inflammation by use of tnf antagonist
ATE175979T1 (de) * 1993-12-27 1999-02-15 Rotkreuzstiftung Zentrallab Verfahren zur herstellung eines konzentrates von anti-d-immunoglobulin g und pharmazeutische zusammensetzung, die dieses enthält
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US6406901B1 (en) 1995-06-08 2002-06-18 Immunex Corporation TNF-a converting enzyme
US5969102A (en) 1997-03-03 1999-10-19 St. Jude Children's Research Hospital Lymphocyte surface receptor that binds CAML, nucleic acids encoding the same and methods of use thereof
IL121900A (en) † 1997-10-07 2001-12-23 Omrix Biopharmaceuticals Ltd A method for the purification of immunoglobulins
ATE370961T1 (de) † 1998-05-06 2007-09-15 Genentech Inc Reinigung von antikörpern durch ionenaustauschchromatographie
ES2228052T3 (es) 1998-06-01 2005-04-01 Genentech, Inc. Separacion demonomeros de anticuerpos de sus multimeros utilizando cromatografia de intercambio de iones.
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US20060257972A1 (en) * 2003-03-31 2006-11-16 Takashi Ishihara Purification of human monoclonal antibody and human polyclonal antibody
TWI353991B (en) * 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
BRPI0415887B1 (pt) 2003-10-27 2021-01-26 Wyeth métodos para a remoção de agregados de elevado peso molecular utilizando cromatografia de hidroxiapatita
BRPI0406605B8 (pt) * 2003-11-13 2021-05-25 Hanmi Holdings Co Ltd conjugado de proteína, método para a preparação do mesmo e composição farmacêutica para intensificar a duração e estabilidade in vivo de um polipeptídeo fisiologicamente ativo
CN1946739A (zh) * 2004-04-14 2007-04-11 豪夫迈－罗氏公司 纯化的白细胞介素－15/Fc融合蛋白及其制备
BRPI0608584B8 (pt) 2005-03-11 2021-05-25 Wyeth Corp métodos de recuperar um produto purificado
WO2006110277A1 (en) * 2005-04-11 2006-10-19 Medarex, Inc. Protein purification using hcic amd ion exchange chromatography
BRPI0611600B8 (pt) * 2005-06-17 2021-05-25 Wyeth Corp método para purificação de uma proteína tendo uma região fc a partir de um líquido fonte compreendendo a proteína e uma ou mais impurezas, e kit
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Also Published As

Publication number Publication date
FI2061803T4 (fi) 2023-03-14
CA2661748C (en) 2016-02-09
US8513393B2 (en) 2013-08-20
CA2661748A1 (en) 2008-03-06
SI2061803T2 (sl) 2023-01-31
HK1131400A1 (en) 2010-01-22
PL2061803T5 (pl) 2023-03-27
EA017152B1 (ru) 2012-10-30
WO2008025748A1 (en) 2008-03-06
KR101770312B1 (ko) 2017-08-22
AU2007291283B2 (en) 2012-09-20
LT2061803T (lt) 2019-11-25
US20100190961A1 (en) 2010-07-29
EP2061803B1 (en) 2019-08-14
AU2007291283A1 (en) 2008-03-06
EA200970231A1 (ru) 2009-08-28
ES2755386T5 (es) 2023-04-05
UA99262C2 (uk) 2012-08-10
KR20090057296A (ko) 2009-06-04
DK2061803T3 (da) 2019-11-18
IL197220A0 (en) 2009-12-24
EP2061803B2 (en) 2022-11-16
AR062570A1 (es) 2008-11-19
SI2061803T1 (sl) 2019-12-31
PT2061803T (pt) 2019-11-21
MX2009002014A (es) 2009-03-09
HUE045898T2 (hu) 2020-01-28
DK2061803T4 (da) 2022-12-05
EP2061803A1 (en) 2009-05-27
ES2755386T3 (es) 2020-04-22
IL197220A (en) 2013-06-27
JP2010501623A (ja) 2010-01-21

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