PL2083863T3 - Przeciwciała przeciwko TGF-beta do stosowania w leczeniu niemowląt obarczonych ryzykiem rozwinięcia się dysplazji oskrzelowo-płucnej - Google Patents
Przeciwciała przeciwko TGF-beta do stosowania w leczeniu niemowląt obarczonych ryzykiem rozwinięcia się dysplazji oskrzelowo-płucnejInfo
- Publication number
- PL2083863T3 PL2083863T3 PL07867199T PL07867199T PL2083863T3 PL 2083863 T3 PL2083863 T3 PL 2083863T3 PL 07867199 T PL07867199 T PL 07867199T PL 07867199 T PL07867199 T PL 07867199T PL 2083863 T3 PL2083863 T3 PL 2083863T3
- Authority
- PL
- Poland
- Prior art keywords
- infants
- tgf
- antibodies
- beta
- risk
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Dispersion Chemistry (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82793306P | 2006-10-03 | 2006-10-03 | |
| EP07867199.7A EP2083863B1 (en) | 2006-10-03 | 2007-10-03 | Antibodies to tgf-beta for use in the treatment of infants at risk of developing bronchopulmonary dysplasia |
| PCT/US2007/021234 WO2008060371A1 (en) | 2006-10-03 | 2007-10-03 | USE OF TGF-β ANTAGONISTS TO TREAT INFANTS AT RISK OF DEVELOPING BRONCHOPULMONARY DYSPLASIA |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2083863T3 true PL2083863T3 (pl) | 2015-08-31 |
Family
ID=39217964
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07867199T PL2083863T3 (pl) | 2006-10-03 | 2007-10-03 | Przeciwciała przeciwko TGF-beta do stosowania w leczeniu niemowląt obarczonych ryzykiem rozwinięcia się dysplazji oskrzelowo-płucnej |
| PL15154393T PL2918288T3 (pl) | 2006-10-03 | 2007-10-03 | Zastosowanie antagonistów TGF beta do leczenia niemowląt obarczonych ryzykiem rozwinięcia dysplazji oskrzelowo-płucnej |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL15154393T PL2918288T3 (pl) | 2006-10-03 | 2007-10-03 | Zastosowanie antagonistów TGF beta do leczenia niemowląt obarczonych ryzykiem rozwinięcia dysplazji oskrzelowo-płucnej |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US8642034B2 (pl) |
| EP (3) | EP2918288B1 (pl) |
| CN (2) | CN101553254A (pl) |
| DK (2) | DK2083863T3 (pl) |
| ES (2) | ES2538265T3 (pl) |
| HU (1) | HUE035575T2 (pl) |
| IL (2) | IL197797A (pl) |
| MX (1) | MX2009003518A (pl) |
| PL (2) | PL2083863T3 (pl) |
| WO (1) | WO2008060371A1 (pl) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140134181A1 (en) * | 2010-11-05 | 2014-05-15 | Kenneth E. Lipson | Treatment Method For Lung Remodeling Diseases |
| WO2014066568A1 (en) | 2012-10-24 | 2014-05-01 | Winthrop-University Hospital | Non-invasive biomarker to identify subjects at risk of preterm delivery |
| WO2014164709A2 (en) | 2013-03-11 | 2014-10-09 | Genzyme Corporation | Engineered anti-tgf-beta antibodies and antigen-binding fragments |
| PL3816625T3 (pl) | 2013-05-06 | 2026-01-26 | Scholar Rock, Inc. | Kompozycje i sposoby modulacji czynnika wzrostu |
| AU2014308751B2 (en) | 2013-08-22 | 2020-03-05 | Acceleron Pharma, Inc. | TGF-beta receptor type II variants and uses thereof |
| TWI733661B (zh) | 2015-03-04 | 2021-07-21 | 美商健臻公司 | 以高親合性、結合性及特異性結合轉化生長因子-β1的經修飾IgG抗體 |
| TWI726870B (zh) | 2015-03-04 | 2021-05-11 | 美商健臻公司 | 具有高親和性、結合性及專一性之結合轉形生長因子-β1的scFv-Fc二聚體 |
| AU2016301380B2 (en) | 2015-08-04 | 2021-07-01 | Acceleron Pharma Inc. | Methods for treating myeloproliferative disorders |
| WO2017044302A1 (en) * | 2015-09-09 | 2017-03-16 | Rush University Medical Center | Compositions and methods for treating bone diseases |
| GB201610044D0 (en) * | 2016-06-08 | 2016-07-20 | Ucb Biopharma Sprl | Antibodies |
| EP4241848A3 (en) | 2017-05-04 | 2023-11-01 | Acceleron Pharma Inc. | Tgf-beta receptor type ii fusion proteins and uses thereof |
| EP3682250A4 (en) | 2017-09-13 | 2021-03-03 | Progenity, Inc. | PRECLAMPSY BIOMARKERS AND RELATED SYSTEMS AND PROCEDURES |
| EP4070113A4 (en) | 2019-12-04 | 2023-12-20 | Biora Therapeutics, Inc. | ASSESSMENT OF PREECLAMPSIA USING FREE AND DISSOCIATE PLACENTAL GROWTH FACTOR TESTS |
Family Cites Families (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS606629A (ja) | 1983-06-23 | 1985-01-14 | Sumitomo Chem Co Ltd | ホルムアルデヒドの製造法 |
| US5262319A (en) | 1985-04-19 | 1993-11-16 | Oncogene Science, Inc. | Method for obtaining bone marrow free of tumor cells using transforming growth factor β3 |
| US5654270A (en) | 1988-06-28 | 1997-08-05 | La Jolla Cancer Research Foundation | Use of fibromodulin to prevent or reduce dermal scarring |
| US5705609A (en) | 1988-06-28 | 1998-01-06 | La Jolla Cancer Research Foundation | Decorin fragments inhibiting cell regulatory factors |
| US5583103A (en) | 1988-06-28 | 1996-12-10 | La Jolla Cancer Research Foundation | Inhibition of transforming growth factor beta activity |
| JP2887325B2 (ja) | 1988-06-28 | 1999-04-26 | ラ ホヤ キャンサー リサーチ ファウンデーション | デコリンによる細胞増殖の抑制 |
| US5571714A (en) | 1988-12-22 | 1996-11-05 | Celtrix Pharmaceuticals, Inc. | Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use |
| JPH0780780B2 (ja) | 1989-09-29 | 1995-08-30 | ラ ホヤ キャンサー リサーチ ファウンデーション | 細胞外マトリックスの蓄積防止のためのトランスフォーミング増殖因子βの阻害 |
| WO1991008291A2 (en) | 1989-11-22 | 1991-06-13 | Genentech, Inc. | Latency associated peptide and uses therefor |
| WO1991010727A1 (en) | 1990-01-22 | 1991-07-25 | La Jolla Cancer Research Foundation | Inhibitors of cell regulatory factors |
| FR2677038B1 (fr) * | 1991-06-03 | 1994-08-12 | Bel Fromageries | Additif alimentaire pour l'alimentation humaine et animale et aliments le contenant. |
| US6008011A (en) | 1991-10-31 | 1999-12-28 | Whitehead Institute For Biomedical Research | TGF-β type II receptor cDNAs |
| EP1149908A1 (en) | 1991-10-31 | 2001-10-31 | Whitehead Institute For Biomedical Research | TGF-beta type receptor cDNAs and uses thereof |
| EP0667784B1 (en) | 1991-11-14 | 2003-03-05 | La Jolla Cancer Research Foundation | Inhibitors of cell regulatory factors and methods for preventing or reducing scarring |
| GB9205800D0 (en) | 1992-03-17 | 1992-04-29 | British Tech Group | Treatment of fibrotic disorders |
| US5821234A (en) | 1992-09-10 | 1998-10-13 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibition of proliferation of vascular smooth muscle cell |
| US5869462A (en) | 1992-09-10 | 1999-02-09 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibition of proliferation of vascular smooth muscle cell |
| WO1994009812A1 (en) | 1992-10-26 | 1994-05-11 | Kirin Brewery Company, Limited | METHOD FOR PRODUCING LARGE LATENT TRANSFORMING GROWTH FACTOR-β COMPLEXES AND LARGE LATENCY ASSOCIATED PEPTIDE |
| WO1994009815A1 (en) | 1992-10-29 | 1994-05-11 | Celtrix Pharmaceuticals, Inc. | USES OF TGF-β RECEPTOR FRAGMENT AS A THERAPEUTIC AGENT |
| AU5541094A (en) | 1992-10-30 | 1994-05-24 | Consejo Superior De Investigaciones Cientificas | Compositions and methods for modifying the regulatory activity of tgf-beta |
| US5830847A (en) | 1992-10-30 | 1998-11-03 | Hsc Research & Development Limited Partnership | Soluble TGF-β-binding endoglin polypeptides and homodimers |
| US6455689B1 (en) | 1993-04-30 | 2002-09-24 | Biognostik Gesellschaft für Biomolekulare Diagnostik mbH | Antisense-oligonucleotides for transforming growth factor-β (TGF-β) |
| WO1995000103A2 (en) | 1993-06-15 | 1995-01-05 | Il-Yang Pharm. Co., Ltd. | Anti-sense oligodeoxynucleotide to fibrogenic cytokines and use thereof |
| WO1995010610A1 (en) | 1993-10-15 | 1995-04-20 | La Jolla Cancer Research Foundation | BETAGLYCAN POLYPEPTIDES HAVING TGF-β BINDING ACTIVITY |
| CA2189340A1 (en) | 1994-05-04 | 1995-11-16 | James W. Dennis | Modulators of cytokines of the tgf-.beta. superfamily and methods for assaying for same |
| US5772995A (en) | 1994-07-18 | 1998-06-30 | Sidney Kimmel Cancer Center | Compositions and methods for enhanced tumor cell immunity in vivo |
| CA2156767A1 (en) | 1994-08-25 | 1996-02-26 | Kenichi Matsunaga | Binding agent for growth factor |
| JPH08119984A (ja) | 1994-08-31 | 1996-05-14 | Nkk Corp | ストレプトミセス属放線菌及びこの菌由来のTGF−β 阻害剤 |
| US5824655A (en) | 1995-02-15 | 1998-10-20 | The University Of Utah | Anti-transforming growth factor-β gene therapy |
| GB9601081D0 (en) | 1995-10-06 | 1996-03-20 | Cambridge Antibody Tech | Specific binding members for human transforming growth factor beta;materials and methods |
| CA2232682A1 (en) | 1996-04-30 | 1997-11-06 | Susan M. Richards | Use of prolactin as a tgf-beta antagonist |
| JPH1067674A (ja) | 1996-06-19 | 1998-03-10 | Advanced Sukin Res Kenkyusho:Kk | 細胞外マトリツクスの異常蓄積抑制剤 |
| JP2001511885A (ja) | 1996-10-25 | 2001-08-14 | エチコン・インコーポレーテツド | 抗―線維症剤アッセイ |
| IL132249A0 (en) | 1997-04-18 | 2001-03-19 | Biogen Inc | Type ii tgf-beta receptor/immunoglobulin constant region fusion proteins |
| US7779020B2 (en) | 2002-03-01 | 2010-08-17 | International Business Machines Corporation | Small-footprint applicative query interpreter method, system and program product |
| US6184226B1 (en) | 1998-08-28 | 2001-02-06 | Scios Inc. | Quinazoline derivatives as inhibitors of P-38 α |
| WO2000047102A2 (en) * | 1999-02-11 | 2000-08-17 | The General Hospital Corporation | COMPOSITIONS AND METHODS FOR MODULATING TGF-β SIGNALING |
| US6492497B1 (en) | 1999-04-30 | 2002-12-10 | Cambridge Antibody Technology Limited | Specific binding members for TGFbeta1 |
| KR100425525B1 (ko) | 2000-11-21 | 2004-03-30 | 재단법인서울대학교산학협력재단 | 조산과 태아감염 및 태아손상을 산전 진단하기 위한진단시약 및 진단키트 |
| DE60143858D1 (de) | 2000-11-28 | 2011-02-24 | Premacure Ab | Reduzierung DES RISIKOS FÜR KOMPLIKATIONEN BEI FRÜHGEBURTEN |
| GB0102673D0 (en) | 2001-02-02 | 2001-03-21 | Glaxo Group Ltd | Compounds |
| JP2004521915A (ja) | 2001-02-02 | 2004-07-22 | グラクソ グループ リミテッド | Tgf過剰発現に対するピラゾール誘導体 |
| GB0102672D0 (en) | 2001-02-02 | 2001-03-21 | Glaxo Group Ltd | Compounds |
| GB0102668D0 (en) | 2001-02-02 | 2001-03-21 | Glaxo Group Ltd | Compounds |
| GB0102665D0 (en) | 2001-02-02 | 2001-03-21 | Glaxo Group Ltd | Compounds |
| EP1363904A1 (en) | 2001-02-02 | 2003-11-26 | Glaxo Group Limited | Pyrazoles as tgf inhibitors |
| ES2289116T3 (es) | 2001-05-24 | 2008-02-01 | Eli Lilly And Company | Nuevos derivados de pirrol como agentes farmaceuticos. |
| BRPI0307070A2 (pt) | 2002-01-22 | 2019-03-26 | Genzyme Corporation | uso de antagonistas tgf-beta para tratar ou prevenir rejeição crônica de transplante |
| AR039241A1 (es) | 2002-04-04 | 2005-02-16 | Biogen Inc | Heteroarilos trisustituidos y metodos para su produccion y uso de los mismos |
| US20050165011A1 (en) | 2002-05-15 | 2005-07-28 | Gellibert Francoise J. | Benzoxazine and benzoxazinone substituted triazoles |
| US20040038856A1 (en) | 2002-05-17 | 2004-02-26 | Sarvajit Chakravarty | Treatment of fibroproliferative disorders using TGF-beta inhibitors |
| EP1575506A4 (en) | 2002-07-25 | 2008-04-23 | Scios Inc | METHOD FOR IMPROVING LUNG FUNCTION WITH TGF-BETA INHIBITORS |
| GB0217786D0 (en) | 2002-07-31 | 2002-09-11 | Glaxo Group Ltd | Compounds |
| UA80295C2 (en) | 2002-09-06 | 2007-09-10 | Biogen Inc | Pyrazolopyridines and using the same |
| UA80296C2 (en) | 2002-09-06 | 2007-09-10 | Biogen Inc | Imidazolopyridines and methods of making and using the same |
| AU2003272324A1 (en) | 2002-09-10 | 2004-04-30 | Scios Inc. | INHIBITORS OF TFGBeta |
| US7365066B2 (en) | 2002-09-17 | 2008-04-29 | Eli Lilly And Company | Pyrazolopyridine derivatives as pharmaceutical agents |
| WO2004026302A1 (en) | 2002-09-19 | 2004-04-01 | Eli Lilly And Company | Methods of inhibiting tgf beta with substituted pyrazoles |
| US20060079680A1 (en) | 2002-11-22 | 2006-04-13 | Eli Lilly And Company Patent Division | Pyrazoloazepine compounds as pharmaceutical agents |
| EP1572208A4 (en) | 2002-11-22 | 2007-08-29 | Scios Inc | METHOD FOR CONTROLLING PATHOLOGICAL CHANGE IN THE BETA-ADRENERGIC PATHWAY |
| WO2004047818A2 (en) | 2002-11-22 | 2004-06-10 | Scios, Inc. | USE OF TFG-β INHIBITORSTO COUNTERACT PATHOLOGIC CHANGES IN THE LEVEL OR FUNCTION OF STEROID/THYROID RECEPTORS |
| UA80571C2 (en) | 2002-11-22 | 2007-10-10 | Lilly Co Eli | Quinolinyl-pyrrolopyrazoles |
| EP1567527A1 (en) | 2002-11-27 | 2005-08-31 | Eli Lilly And Company | Condensed pyrazolo derivatives |
| WO2004056352A1 (en) | 2002-12-19 | 2004-07-08 | Scios, Inc. | TREATMENT OF OBESITY AND ASSOCIATED CONDITIONS WITH TGF-β INHIBITORS |
| EP1590668A2 (en) | 2003-02-06 | 2005-11-02 | Adeza Biomedical Corporation | Screeninig and treatment methods for prevention of preterm delivery |
| CL2004000234A1 (es) | 2003-02-12 | 2005-04-15 | Biogen Idec Inc | Compuestos derivados 3-(piridin-2-il)-4-heteroaril-pirazol sustituidos, antagonistas de aik5 y/o aik4; composicion farmaceutica y uso del compuesto en el tratamiento de desordenes fibroticos como esclerodermia, lupus nefritico, cicatrizacion de herid |
| US7223766B2 (en) | 2003-03-28 | 2007-05-29 | Scios, Inc. | Bi-cyclic pyrimidine inhibitors of TGFβ |
| EP1646655A2 (en) | 2003-07-09 | 2006-04-19 | Eli Lilly And Company | Tgf-beta1 ligands |
| US7232824B2 (en) | 2003-09-30 | 2007-06-19 | Scios, Inc. | Quinazoline derivatives as medicaments |
| RU2006122519A (ru) | 2003-12-24 | 2008-01-27 | Сайос, Инк. (Us) | Лечение злокачественных глиом ингибиторами тфр-бэта |
| WO2005092894A1 (en) | 2004-03-01 | 2005-10-06 | Eli Lilly And Company | Fused pyrazole derivatives as tgf-beta signal transduction inhibitors for the treatment of fibrosis and neoplasms |
| NZ550217A (en) * | 2004-03-31 | 2009-11-27 | Genentech Inc | Humanized anti-TGF-beta antibodies |
| DE102004019253A1 (de) | 2004-04-16 | 2005-11-10 | Codewrights Gmbh | Verfahren zum Fernbedienen eines Feldgerätes der Prozessautomatisierungstechnik |
| JP2008513356A (ja) * | 2004-08-09 | 2008-05-01 | アリオス バイオファーマ インク. | 合成高度糖鎖付加プロテアーゼ耐性ポリペプチド変異体、それを使用する経口製剤および方法 |
| WO2006026306A1 (en) | 2004-08-31 | 2006-03-09 | Biogen Idec Ma Inc. | Pyrimidinylimidazoles as tgf-beta inhibitors |
| CA2578628A1 (en) | 2004-08-31 | 2006-03-09 | Biogen Idec Ma Inc. | Pyrimidinylpyrazoles as tgf-beta inhibitors |
| US7511056B2 (en) | 2004-11-10 | 2009-03-31 | Eli Lilly And Company | TGF-β inhibitors |
| BRPI0607639B1 (pt) * | 2005-02-08 | 2022-04-05 | Genzyme Corporation | Moléculas de anticorpo humano ou fragmento de ligação a antígeno das mesmas que se ligam e neutralizam tgf-beta1, 2 e 3, uso das mesmas e composição farmacêutica |
-
2007
- 2007-10-03 PL PL07867199T patent/PL2083863T3/pl unknown
- 2007-10-03 CN CNA2007800447494A patent/CN101553254A/zh active Pending
- 2007-10-03 WO PCT/US2007/021234 patent/WO2008060371A1/en not_active Ceased
- 2007-10-03 DK DK07867199.7T patent/DK2083863T3/da active
- 2007-10-03 MX MX2009003518A patent/MX2009003518A/es active IP Right Grant
- 2007-10-03 EP EP15154393.1A patent/EP2918288B1/en active Active
- 2007-10-03 US US12/444,059 patent/US8642034B2/en not_active Expired - Fee Related
- 2007-10-03 ES ES07867199.7T patent/ES2538265T3/es active Active
- 2007-10-03 EP EP07867199.7A patent/EP2083863B1/en not_active Not-in-force
- 2007-10-03 DK DK15154393.1T patent/DK2918288T3/da active
- 2007-10-03 CN CN201510002215.1A patent/CN104645328A/zh active Pending
- 2007-10-03 ES ES15154393.1T patent/ES2647472T3/es active Active
- 2007-10-03 HU HUE15154393A patent/HUE035575T2/en unknown
- 2007-10-03 PL PL15154393T patent/PL2918288T3/pl unknown
- 2007-10-03 EP EP17181294.4A patent/EP3254696A1/en not_active Withdrawn
-
2009
- 2009-03-25 IL IL197797A patent/IL197797A/en active IP Right Grant
-
2013
- 2013-12-23 US US14/139,332 patent/US20140199399A1/en not_active Abandoned
-
2016
- 2016-11-28 US US15/362,392 patent/US20170233464A1/en not_active Abandoned
-
2017
- 2017-04-27 IL IL251994A patent/IL251994B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| IL197797A (en) | 2017-05-29 |
| CN101553254A (zh) | 2009-10-07 |
| PL2918288T3 (pl) | 2018-02-28 |
| US20170233464A1 (en) | 2017-08-17 |
| IL197797A0 (en) | 2011-08-01 |
| EP2918288A1 (en) | 2015-09-16 |
| EP2083863A1 (en) | 2009-08-05 |
| IL251994A0 (en) | 2017-06-29 |
| CN104645328A (zh) | 2015-05-27 |
| EP2918288B1 (en) | 2017-08-16 |
| WO2008060371A1 (en) | 2008-05-22 |
| MX2009003518A (es) | 2009-08-25 |
| EP2083863B1 (en) | 2015-03-18 |
| US20140199399A1 (en) | 2014-07-17 |
| DK2918288T3 (da) | 2017-11-27 |
| IL251994B (en) | 2021-01-31 |
| WO2008060371A8 (en) | 2008-07-10 |
| ES2647472T3 (es) | 2017-12-21 |
| DK2083863T3 (da) | 2015-06-22 |
| US8642034B2 (en) | 2014-02-04 |
| EP3254696A1 (en) | 2017-12-13 |
| US20100008911A1 (en) | 2010-01-14 |
| HUE035575T2 (en) | 2018-05-28 |
| ES2538265T3 (es) | 2015-06-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL2083863T3 (pl) | Przeciwciała przeciwko TGF-beta do stosowania w leczeniu niemowląt obarczonych ryzykiem rozwinięcia się dysplazji oskrzelowo-płucnej | |
| DK2069403T3 (da) | Human-antistoffer med høj affinitet for human IL-4 receptor | |
| ZA201000075B (en) | Purin derivatives for use in the treatment of fab-related diseases | |
| PL2391650T3 (pl) | Sposoby leczenia dny | |
| ZA201003131B (en) | Anti-rsv g protein antibodies | |
| IL228988A (en) | Antibody preparations for the treatment of vaccine-related diseases | |
| HUE048024T2 (hu) | Anakinra bronchiolitis obliterans szindróma kezelésében való alkalmazásra | |
| PL2152290T3 (pl) | Sposoby podawania przeciwciał przeciw IL-5 | |
| ZA200808865B (en) | Antibody composition and methods for treatment of neoplastic disease | |
| DK2356151T3 (da) | Human-antistoffer med høj affinitet for human IL-4 receptor | |
| IL210802A0 (en) | Purin derivatives for use in the treatment of fab-related diseases | |
| HUE054495T2 (hu) | Rák kezelésére szolgáló készítmény | |
| PL1993577T3 (pl) | Stosowanie nieulegających trawieniu sacharydów dla zapewnienia niemowlęciu najlepszego startu po narodzinach | |
| BR112012004546A2 (pt) | "terapêutica por proteínas ligantes dll4-ligantes" | |
| PT2426148E (pt) | Anticorpo anti-rá-il-3 para se utilizar no tratamento de tumores do sangue | |
| ZA200905990B (en) | Recombinant antibodies for treatment of respriratory syncytial virus infections | |
| PL2061485T3 (pl) | Peptydy EV576 do zastosowania w leczeniu zespołu Guillaina-Barrégo | |
| IL195152A (en) | Compounds for use in treating diseases of cell culture | |
| EP2200553A4 (en) | LIGHT ABSORBENT TRANSPORT DEVICE | |
| IL232011A0 (en) | Antibodies to 7egfl and methods of using them | |
| IL206450A0 (en) | Use of an acetylsalicylic acid salt for the treatment of viral infections | |
| DE112009003128A5 (de) | Aggregat zur nutzung alternativer energie | |
| ZA200904068B (en) | Anti-tsg101 antibodies and their uses for treatment of viral infections | |
| EP2094128A4 (en) | DISPOSABLE COVER FOR USE IN A PREMATURE COVER | |
| GB0620695D0 (en) | Composition and methods for the treatment of nurdegenerative disease |