PL213098A1 - - Google Patents

Info

Publication number
PL213098A1
PL213098A1 PL21309879A PL21309879A PL213098A1 PL 213098 A1 PL213098 A1 PL 213098A1 PL 21309879 A PL21309879 A PL 21309879A PL 21309879 A PL21309879 A PL 21309879A PL 213098 A1 PL213098 A1 PL 213098A1
Authority
PL
Poland
Application number
PL21309879A
Other versions
PL121468B1 (en
Inventor
John J Savarese
Richard J Kitz
Sara Ginsburg
Original Assignee
Massachusetts Gen Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Gen Hospital filed Critical Massachusetts Gen Hospital
Publication of PL213098A1 publication Critical patent/PL213098A1/xx
Publication of PL121468B1 publication Critical patent/PL121468B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41Preparation of salts of carboxylic acids
    • C07C51/412Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/10Quaternary compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL1979213098A 1978-07-21 1979-01-30 Process for preparing novel salts of bis-tetrahydroiso-quinolinium-alkyl m-or p-phenylene-di/methan or ethen/-carboxylatesan/karboksilanov bis-tetragidroizokhinolinio-alkilovykh solejj PL121468B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92679478A 1978-07-21 1978-07-21

Publications (2)

Publication Number Publication Date
PL213098A1 true PL213098A1 (da) 1980-03-24
PL121468B1 PL121468B1 (en) 1982-05-31

Family

ID=25453730

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1979213098A PL121468B1 (en) 1978-07-21 1979-01-30 Process for preparing novel salts of bis-tetrahydroiso-quinolinium-alkyl m-or p-phenylene-di/methan or ethen/-carboxylatesan/karboksilanov bis-tetragidroizokhinolinio-alkilovykh solejj

Country Status (14)

Country Link
EP (1) EP0010119A1 (da)
JP (1) JPS5517367A (da)
AU (1) AU522421B2 (da)
CA (1) CA1125287A (da)
DD (1) DD142547A5 (da)
DK (1) DK34979A (da)
ES (1) ES477257A1 (da)
FI (1) FI790214A7 (da)
IE (1) IE790108L (da)
IL (1) IL56487A (da)
IT (1) IT1202871B (da)
MC (1) MC1240A1 (da)
PL (1) PL121468B1 (da)
ZA (1) ZA79253B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8418303D0 (en) * 1984-07-18 1984-08-22 Wellcome Found Compounds
BG41897A1 (en) * 1985-07-19 1987-09-15 Ivanov Dichlormethylate of n, n'- 4, 10- dioxa- 3, 11- bis- tetrahydropapaverine and method for its preparation
US5240939A (en) * 1991-10-31 1993-08-31 Anaquest, Inc. Nitrogen bridge tetrahydroisoquinolines
CN103880744A (zh) * 2012-12-21 2014-06-25 常州工程职业技术学院 一种5’-甲氧基劳丹素的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2662083A (en) * 1950-10-24 1953-12-08 Allen & Hanburys Ltd Heterocyclic polymethylene-bisquaternary ammonium salts and process for preparing same
GB863717A (en) * 1958-07-03 1961-03-22 Allen & Hanburys Ltd Tetrahydropapaverine derivatives and their preparation
GB1125619A (en) * 1965-11-15 1968-08-28 Wellcome Found Derivatives of bis-isoquinolines
AU506657B2 (en) * 1975-12-10 1980-01-17 Wellcome Foundation Limited, The Isoquinoline derivatives
JPS5455577A (en) * 1977-08-01 1979-05-02 Masachiyuusetsutsu Gen Hosupit Blocking agent of neuromuscle

Also Published As

Publication number Publication date
IL56487A0 (en) 1979-03-12
IL56487A (en) 1983-05-15
ZA79253B (en) 1980-06-25
IT7919694A0 (it) 1979-01-29
JPS5517367A (en) 1980-02-06
AU4368879A (en) 1980-01-24
MC1240A1 (fr) 1979-10-26
AU522421B2 (en) 1982-06-03
EP0010119A1 (en) 1980-04-30
CA1125287A (en) 1982-06-08
IT1202871B (it) 1989-02-15
DK34979A (da) 1980-01-22
IE790108L (en) 1980-01-21
ES477257A1 (es) 1979-08-01
FI790214A7 (fi) 1980-01-22
DD142547A5 (de) 1980-07-02
PL121468B1 (en) 1982-05-31

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