PL2167526T3 - Oczyszczanie czynnika VIII za pomocą żywicy o mieszanej funkcji lub wielofunkcyjnej - Google Patents

Oczyszczanie czynnika VIII za pomocą żywicy o mieszanej funkcji lub wielofunkcyjnej

Info

Publication number
PL2167526T3
PL2167526T3 PL08786090T PL08786090T PL2167526T3 PL 2167526 T3 PL2167526 T3 PL 2167526T3 PL 08786090 T PL08786090 T PL 08786090T PL 08786090 T PL08786090 T PL 08786090T PL 2167526 T3 PL2167526 T3 PL 2167526T3
Authority
PL
Poland
Prior art keywords
purification
factor viii
mixed
mode
multimodal resin
Prior art date
Application number
PL08786090T
Other languages
English (en)
Inventor
Susanne Bang
Lars Thim
Johan Karlsson
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of PL2167526T3 publication Critical patent/PL2167526T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL08786090T 2007-07-11 2008-07-11 Oczyszczanie czynnika VIII za pomocą żywicy o mieszanej funkcji lub wielofunkcyjnej PL2167526T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07112287 2007-07-11
EP08786090A EP2167526B1 (en) 2007-07-11 2008-07-11 Purification of factor viii using a mixed-mode or multimodal resin
PCT/EP2008/059094 WO2009007451A1 (en) 2007-07-11 2008-07-11 Purification of factor viii using a mixed-mode or multimodal resin

Publications (1)

Publication Number Publication Date
PL2167526T3 true PL2167526T3 (pl) 2011-09-30

Family

ID=38472947

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08786090T PL2167526T3 (pl) 2007-07-11 2008-07-11 Oczyszczanie czynnika VIII za pomocą żywicy o mieszanej funkcji lub wielofunkcyjnej

Country Status (15)

Country Link
US (1) US8399620B2 (pl)
EP (1) EP2167526B1 (pl)
JP (1) JP5323072B2 (pl)
KR (1) KR101293504B1 (pl)
CN (1) CN101730707B (pl)
AT (1) ATE503763T1 (pl)
AU (1) AU2008274195B2 (pl)
BR (1) BRPI0814220B8 (pl)
CA (1) CA2692814A1 (pl)
DE (1) DE602008005885D1 (pl)
ES (1) ES2364118T3 (pl)
NL (1) NL300663I2 (pl)
PL (1) PL2167526T3 (pl)
RU (1) RU2493163C2 (pl)
WO (1) WO2009007451A1 (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160104740A (ko) * 2008-06-24 2016-09-05 옥타파마 아게 응고 인자 ｖｉｉｉ을 정제하는 방법
CN102119172A (zh) 2008-08-21 2011-07-06 奥克塔法马股份有限公司 重组制备的人类因子viii和ix
US8945895B2 (en) 2009-07-31 2015-02-03 Baxter International Inc. Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof
US8277649B2 (en) 2009-12-14 2012-10-02 General Electric Company Membranes and associated methods for purification of antibodies
DK2538968T3 (en) * 2010-02-24 2017-12-11 Chiesi Farm Spa PROCEDURE FOR THE PREPARATION AND PURIFICATION OF RECOMBINANT LYSOSOMAL ALFA MANNOSIDASE
DK2552948T3 (en) 2010-03-30 2016-10-17 Octapharma Ag A process for the purification of the protein growth factor G-CSF
EP2553095B1 (en) 2010-03-30 2016-10-12 Octapharma AG A process for purifying vitamin K dependent proteins such as coagulation factor IX
RU2591523C2 (ru) * 2010-11-05 2016-07-20 Ф. Хоффманн-Ля Рош Аг Оптимизированный метод захвата антител хроматографией смешанного типа
CA2821711C (en) 2010-12-15 2017-10-10 Baxter International Inc. Eluate collection using conductivity gradient
WO2013075740A1 (en) 2011-11-23 2013-05-30 Sanofi Antibody purification method
US20150275195A1 (en) 2012-10-24 2015-10-01 Genzyme Corporation Elution of biomolecules from multi-modal resins using mes and mops as mobile phase modifiers
US20140154233A1 (en) 2012-12-05 2014-06-05 Csl Limited Method of purifying therapeutic proteins
US10188965B2 (en) 2012-12-05 2019-01-29 Csl Behring Gmbh Hydrophobic charge induction chromatographic depletion of a protein from a solution
CN103396494B (zh) * 2013-04-27 2015-04-01 江苏省疾病预防控制中心 一种凝血因子ix的单克隆抗体
NO2994485T3 (pl) 2013-05-06 2018-06-09
US10370408B2 (en) * 2014-06-25 2019-08-06 Jhl Biotech, Inc. Method for purification of a DNase or RNase protein from a sample
US10238718B2 (en) 2014-08-04 2019-03-26 Csl Limited Factor VIII formulation
ES2772933T3 (es) 2015-03-06 2020-07-08 CSL Behring Lengnau AG Factor de von Willebrand modificado que tiene una semivida mejorada
GB201506113D0 (en) * 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
GB201506117D0 (en) 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
EP3205665A1 (en) * 2016-02-11 2017-08-16 Octapharma AG Method of separating factor viii from blood products
GB201617240D0 (en) * 2016-10-11 2016-11-23 Profactor Pharma Ltd Purification process
EP3642225A1 (en) 2017-06-23 2020-04-29 Baxalta Incorporated Purification of factor viii subspecies
EP3546475A1 (en) 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
CN114072420B (zh) 2019-07-04 2024-06-11 康诺贝林伦瑙有限公司 用于增加凝血因子viii的体外稳定性的截短的血管性血友病因子(vwf)
JP7680442B2 (ja) 2019-11-11 2025-05-20 ツェー・エス・エル・ベーリング・レングナウ・アクチエンゲゼルシャフト 第ｖｉｉｉ因子に対する寛容を誘導するためのポリペプチド

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9302006D0 (sv) * 1992-10-02 1993-06-11 Kabi Pharmacia Ab Protein formulation
SE9301581D0 (sv) * 1993-05-07 1993-05-07 Kabi Pharmacia Ab Protein formulation
SE503424C2 (sv) * 1994-11-14 1996-06-10 Pharmacia Ab Process för rening av rekombinant koagulationsfaktor VIII
IL157309A0 (en) 2003-08-07 2004-02-19 Applied Research Systems Method for the purification of a non-immunoglobulin protein
ES2395544T3 (es) * 2004-12-23 2013-02-13 Novo Nordisk Health Care Ag Reducción del contenido de contaminantes proteínicos en composiciones que comprenden una proteína dependiente de la vitamina K de interés
EP1707634A1 (en) * 2005-03-29 2006-10-04 Octapharma AG Method for isolation of recombinantly produced proteins
KR20160104740A (ko) 2008-06-24 2016-09-05 옥타파마 아게 응고 인자 ｖｉｉｉ을 정제하는 방법

Also Published As

Publication number Publication date
JP5323072B2 (ja) 2013-10-23
BRPI0814220A2 (pt) 2015-01-06
ES2364118T3 (es) 2011-08-25
EP2167526A1 (en) 2010-03-31
BRPI0814220B1 (pt) 2019-09-17
KR101293504B1 (ko) 2013-08-07
EP2167526B1 (en) 2011-03-30
RU2010103528A (ru) 2011-08-20
AU2008274195B2 (en) 2013-09-05
WO2009007451A1 (en) 2009-01-15
AU2008274195A1 (en) 2009-01-15
KR20100051620A (ko) 2010-05-17
NL300663I2 (pl) 2016-09-22
US20100204452A1 (en) 2010-08-12
RU2493163C2 (ru) 2013-09-20
CA2692814A1 (en) 2009-01-15
CN101730707A (zh) 2010-06-09
ATE503763T1 (de) 2011-04-15
ES2364118T9 (es) 2014-05-19
BRPI0814220B8 (pt) 2021-05-25
CN101730707B (zh) 2014-12-17
DE602008005885D1 (de) 2011-05-12
JP2010533150A (ja) 2010-10-21
US8399620B2 (en) 2013-03-19

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