PL2212330T3 - Nowe związki stanowiące mimetyki zakrętu beta i ich zastosowanie - Google Patents

Nowe związki stanowiące mimetyki zakrętu beta i ich zastosowanie

Info

Publication number
PL2212330T3
PL2212330T3 PL08840475T PL08840475T PL2212330T3 PL 2212330 T3 PL2212330 T3 PL 2212330T3 PL 08840475 T PL08840475 T PL 08840475T PL 08840475 T PL08840475 T PL 08840475T PL 2212330 T3 PL2212330 T3 PL 2212330T3
Authority
PL
Poland
Prior art keywords
novel compounds
reverse turn
turn mimetics
mimetics
reverse
Prior art date
Application number
PL08840475T
Other languages
English (en)
Inventor
Jae Uk Chung
Kyung-Yun Jung
Min-Wook Jeong
Hee-Kyung Jung
Hyun-Ju La
Original Assignee
Jw Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jw Pharmaceutical Corp filed Critical Jw Pharmaceutical Corp
Publication of PL2212330T3 publication Critical patent/PL2212330T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PL08840475T 2007-10-15 2008-10-15 Nowe związki stanowiące mimetyki zakrętu beta i ich zastosowanie PL2212330T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/974,941 US7671054B1 (en) 2001-10-12 2007-10-15 Reverse-turn mimetics and method relating thereto
EP08840475.1A EP2212330B1 (en) 2007-10-15 2008-10-15 Novel compounds of reverse turn mimetics and the use thereof (3)
PCT/KR2008/006070 WO2009051397A2 (en) 2007-10-15 2008-10-15 Novel compounds of reverse turn mimetics and the use thereof (3)

Publications (1)

Publication Number Publication Date
PL2212330T3 true PL2212330T3 (pl) 2015-09-30

Family

ID=40567948

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08840475T PL2212330T3 (pl) 2007-10-15 2008-10-15 Nowe związki stanowiące mimetyki zakrętu beta i ich zastosowanie

Country Status (13)

Country Link
US (4) US7671054B1 (pl)
EP (3) EP2212328B1 (pl)
JP (3) JP5222948B2 (pl)
KR (3) KR101542921B1 (pl)
CN (4) CN101896485A (pl)
AU (2) AU2008312191B2 (pl)
BR (2) BRPI0818511B1 (pl)
CA (2) CA2702461C (pl)
ES (3) ES2622703T3 (pl)
MX (2) MX2010004046A (pl)
PL (1) PL2212330T3 (pl)
RU (2) RU2457210C2 (pl)
WO (3) WO2009051399A2 (pl)

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KR101441406B1 (ko) * 2011-05-25 2014-11-04 주식회사 바이오이미징코리아 디아릴이오도늄 염 전구체를 이용한 플로오린-18이 표지된 플루마제닐의 제조 방법
WO2013022257A2 (ko) * 2011-08-09 2013-02-14 제이더블유중외제약 주식회사 피라지노-트리아진 유도체를 포함하는 비소세포성폐암 예방 및 치료용 조성물
US9353119B2 (en) * 2011-08-09 2016-05-31 Jw Pharmaceutical Corporation Composition for preventing and treating non-small cell lung cancer, containing pyrazino-triazine derivatives
KR20140053952A (ko) * 2011-08-26 2014-05-08 제이더블유중외제약 주식회사 피라지노-트리아진 유도체를 포함하는 조성물
BR112014008360A2 (pt) 2011-10-07 2017-04-25 Univ Southern California cbp/catenina antagonistas para melhorar divisão assimétrica de células-tronco somáticas
GB201315335D0 (en) * 2013-08-29 2013-10-09 Of Singapore Amino diacids containing peptide modifiers
SG11201601767YA (en) * 2013-09-11 2016-04-28 Prism Pharma Co Ltd Method of producing pyrazino[2,1-c][1,2,4]triazine compound
US9174998B2 (en) 2013-12-25 2015-11-03 Eisai R&D Management Co., Ltd. (6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-4,7-dioxo-8-({6-[3-(piperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-2-(prop-2-en-1-yl)-octahydro-1H-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide compound
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GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy
CN108026104B (zh) * 2015-09-18 2021-06-18 国立大学法人鸟取大学 利用低分子化合物的癌及纤维化的抑制和再生促进的效果
US20190125753A1 (en) * 2016-04-20 2019-05-02 University Of Southern California Compounds and methods for increasing hematopoiesis
US12303505B2 (en) 2017-02-08 2025-05-20 Eisai R&D Management Co., Ltd. Tumor-treating pharmaceutical composition
BR112019023064A2 (pt) 2017-05-16 2020-06-09 Eisai R&D Man Co Ltd tratamento de carcinoma hepatocelular
CN110950873A (zh) * 2019-12-10 2020-04-03 河南大学 坡尔吲哚的合成新方法
US12486275B2 (en) 2020-03-12 2025-12-02 City Of Hope Substituted pyrazino[2,1-c][1,2,4]triazines as Wnt/CBP/catenin signaling pathway inhibitors
KR20220151178A (ko) 2020-03-12 2022-11-14 3＋2 파마, 엘엘씨 Cbp/카테닌 신호전달 경로 억제제 및 그것의 용도
KR20230129222A (ko) 2020-10-05 2023-09-07 제네시스 몰레큘러 테크놀로지스, 인코포레이티드 피부과 응용을 위한 국부 제제
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WO2024052684A1 (en) 2022-09-09 2024-03-14 MyricX Pharma Limited Antibody drug conjugate comprising nmt inhibitor and its use

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JP5536336B2 (ja) * 2005-11-08 2014-07-02 チョンウェ ファーマ コーポレイション α−ヘリックス類似体および癌幹細胞の治療に関する方法
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Also Published As

Publication number Publication date
RU2470024C2 (ru) 2012-12-20
JP2011500667A (ja) 2011-01-06
AU2008312193B2 (en) 2012-10-18
EP2212328A4 (en) 2011-11-30
AU2008312193A1 (en) 2009-04-23
US8138337B2 (en) 2012-03-20
CN101827850B (zh) 2014-03-12
WO2009051397A3 (en) 2009-06-04
BRPI0818647B1 (pt) 2021-10-26
KR20100085107A (ko) 2010-07-28
MX2010004046A (es) 2010-06-25
EP2212329A2 (en) 2010-08-04
EP2212330B1 (en) 2015-04-08
ES2509042T3 (es) 2014-10-16
JP5400785B2 (ja) 2014-01-29
RU2457210C2 (ru) 2012-07-27
EP2212330A2 (en) 2010-08-04
CA2702461A1 (en) 2009-04-23
EP2212328A2 (en) 2010-08-04
JP2011500666A (ja) 2011-01-06
JP2011500668A (ja) 2011-01-06
BRPI0818647A2 (pt) 2015-04-07
EP2212330A4 (en) 2011-11-30
US20100222303A1 (en) 2010-09-02
KR101229504B1 (ko) 2013-02-04
CN101827850A (zh) 2010-09-08
RU2010119468A (ru) 2011-11-27
EP2212329B1 (en) 2014-07-30
BRPI0818511B1 (pt) 2021-09-21
US8049008B2 (en) 2011-11-01
CA2701735A1 (en) 2009-04-23
AU2008312191B2 (en) 2012-07-05
KR20100099116A (ko) 2010-09-10
CN101896485A (zh) 2010-11-24
WO2009051397A2 (en) 2009-04-23
ES2541459T3 (es) 2015-07-20
KR101269420B1 (ko) 2013-05-30
WO2009051399A3 (en) 2009-06-04
AU2008312191A1 (en) 2009-04-23
WO2009051397A9 (en) 2010-05-27
CN101827849B (zh) 2013-07-24
EP2212329A4 (en) 2011-11-30
BRPI0818511A2 (pt) 2015-06-16
JP5222948B2 (ja) 2013-06-26
KR20100085102A (ko) 2010-07-28
WO2009051399A2 (en) 2009-04-23
RU2010119447A (ru) 2011-11-27
CN103539797B (zh) 2016-05-18
CN103539797A (zh) 2014-01-29
JP5222949B2 (ja) 2013-06-26
US20100228027A1 (en) 2010-09-09
CA2701735C (en) 2012-12-11
MX2010004045A (es) 2010-07-06
WO2009051398A3 (en) 2009-06-04
ES2622703T3 (es) 2017-07-07
KR101542921B1 (ko) 2015-08-11
CA2702461C (en) 2012-12-11
US20100240662A1 (en) 2010-09-23
CN101827849A (zh) 2010-09-08
EP2212328B1 (en) 2017-01-25
US8071764B2 (en) 2011-12-06
US7671054B1 (en) 2010-03-02
WO2009051398A2 (en) 2009-04-23

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