BRPI0818647A2 - Compostos de miméticos de volta reversa e o uso dos mesmos (3) - Google Patents

Compostos de miméticos de volta reversa e o uso dos mesmos (3)

Info

Publication number
BRPI0818647A2
BRPI0818647A2 BRPI0818647A BRPI0818647A2 BR PI0818647 A2 BRPI0818647 A2 BR PI0818647A2 BR PI0818647 A BRPI0818647 A BR PI0818647A BR PI0818647 A2 BRPI0818647 A2 BR PI0818647A2
Authority
BR
Brazil
Prior art keywords
mimetic compounds
reverse back
reverse
mimetic
compounds
Prior art date
Application number
Other languages
English (en)
Inventor
Jae Uk Chung
Kyung-Yun Jung
Min-Wook Jeong
Hee-Kyung Jung
Hyun-Ju La
Original Assignee
Choongwae Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Choongwae Pharma Corp filed Critical Choongwae Pharma Corp
Publication of BRPI0818647A2 publication Critical patent/BRPI0818647A2/pt
Publication of BRPI0818647B1 publication Critical patent/BRPI0818647B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BRPI0818647-2A 2007-10-15 2008-10-15 Compostos de miméticos de volta reversa e uso dos mesmos para tratar ou prevenir leucemia mielóide aguda BRPI0818647B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/974,941 US7671054B1 (en) 2001-10-12 2007-10-15 Reverse-turn mimetics and method relating thereto
US11/974.941 2007-10-15
PCT/KR2008/006070 WO2009051397A2 (en) 2007-10-15 2008-10-15 Novel compounds of reverse turn mimetics and the use thereof (3)

Publications (2)

Publication Number Publication Date
BRPI0818647A2 true BRPI0818647A2 (pt) 2015-04-07
BRPI0818647B1 BRPI0818647B1 (pt) 2021-10-26

Family

ID=40567948

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0818511-5A BRPI0818511B1 (pt) 2007-10-15 2008-10-15 Compostos de miméticos de giro reverso e uso dos mesmos para tratar ou prevenir leucemia mielóide aguda
BRPI0818647-2A BRPI0818647B1 (pt) 2007-10-15 2008-10-15 Compostos de miméticos de volta reversa e uso dos mesmos para tratar ou prevenir leucemia mielóide aguda

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BRPI0818511-5A BRPI0818511B1 (pt) 2007-10-15 2008-10-15 Compostos de miméticos de giro reverso e uso dos mesmos para tratar ou prevenir leucemia mielóide aguda

Country Status (13)

Country Link
US (4) US7671054B1 (pt)
EP (3) EP2212328B1 (pt)
JP (3) JP5222948B2 (pt)
KR (3) KR101542921B1 (pt)
CN (4) CN101896485A (pt)
AU (2) AU2008312191B2 (pt)
BR (2) BRPI0818511B1 (pt)
CA (2) CA2702461C (pt)
ES (3) ES2622703T3 (pt)
MX (2) MX2010004046A (pt)
PL (1) PL2212330T3 (pt)
RU (2) RU2457210C2 (pt)
WO (3) WO2009051399A2 (pt)

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US9353119B2 (en) * 2011-08-09 2016-05-31 Jw Pharmaceutical Corporation Composition for preventing and treating non-small cell lung cancer, containing pyrazino-triazine derivatives
KR20140053952A (ko) * 2011-08-26 2014-05-08 제이더블유중외제약 주식회사 피라지노-트리아진 유도체를 포함하는 조성물
BR112014008360A2 (pt) 2011-10-07 2017-04-25 Univ Southern California cbp/catenina antagonistas para melhorar divisão assimétrica de células-tronco somáticas
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CN108026104B (zh) * 2015-09-18 2021-06-18 国立大学法人鸟取大学 利用低分子化合物的癌及纤维化的抑制和再生促进的效果
US20190125753A1 (en) * 2016-04-20 2019-05-02 University Of Southern California Compounds and methods for increasing hematopoiesis
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BR112019023064A2 (pt) 2017-05-16 2020-06-09 Eisai R&D Man Co Ltd tratamento de carcinoma hepatocelular
CN110950873A (zh) * 2019-12-10 2020-04-03 河南大学 坡尔吲哚的合成新方法
US12486275B2 (en) 2020-03-12 2025-12-02 City Of Hope Substituted pyrazino[2,1-c][1,2,4]triazines as Wnt/CBP/catenin signaling pathway inhibitors
KR20220151178A (ko) 2020-03-12 2022-11-14 3＋2 파마, 엘엘씨 Cbp/카테닌 신호전달 경로 억제제 및 그것의 용도
KR20230129222A (ko) 2020-10-05 2023-09-07 제네시스 몰레큘러 테크놀로지스, 인코포레이티드 피부과 응용을 위한 국부 제제
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JP5536336B2 (ja) * 2005-11-08 2014-07-02 チョンウェ ファーマ コーポレイション α−ヘリックス類似体および癌幹細胞の治療に関する方法
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Also Published As

Publication number Publication date
RU2470024C2 (ru) 2012-12-20
JP2011500667A (ja) 2011-01-06
AU2008312193B2 (en) 2012-10-18
EP2212328A4 (en) 2011-11-30
AU2008312193A1 (en) 2009-04-23
US8138337B2 (en) 2012-03-20
CN101827850B (zh) 2014-03-12
WO2009051397A3 (en) 2009-06-04
BRPI0818647B1 (pt) 2021-10-26
KR20100085107A (ko) 2010-07-28
MX2010004046A (es) 2010-06-25
EP2212329A2 (en) 2010-08-04
EP2212330B1 (en) 2015-04-08
ES2509042T3 (es) 2014-10-16
JP5400785B2 (ja) 2014-01-29
RU2457210C2 (ru) 2012-07-27
EP2212330A2 (en) 2010-08-04
CA2702461A1 (en) 2009-04-23
EP2212328A2 (en) 2010-08-04
JP2011500666A (ja) 2011-01-06
JP2011500668A (ja) 2011-01-06
EP2212330A4 (en) 2011-11-30
US20100222303A1 (en) 2010-09-02
KR101229504B1 (ko) 2013-02-04
CN101827850A (zh) 2010-09-08
RU2010119468A (ru) 2011-11-27
EP2212329B1 (en) 2014-07-30
BRPI0818511B1 (pt) 2021-09-21
US8049008B2 (en) 2011-11-01
CA2701735A1 (en) 2009-04-23
AU2008312191B2 (en) 2012-07-05
KR20100099116A (ko) 2010-09-10
CN101896485A (zh) 2010-11-24
WO2009051397A2 (en) 2009-04-23
ES2541459T3 (es) 2015-07-20
KR101269420B1 (ko) 2013-05-30
WO2009051399A3 (en) 2009-06-04
AU2008312191A1 (en) 2009-04-23
WO2009051397A9 (en) 2010-05-27
CN101827849B (zh) 2013-07-24
EP2212329A4 (en) 2011-11-30
BRPI0818511A2 (pt) 2015-06-16
JP5222948B2 (ja) 2013-06-26
KR20100085102A (ko) 2010-07-28
WO2009051399A2 (en) 2009-04-23
RU2010119447A (ru) 2011-11-27
CN103539797B (zh) 2016-05-18
CN103539797A (zh) 2014-01-29
JP5222949B2 (ja) 2013-06-26
US20100228027A1 (en) 2010-09-09
CA2701735C (en) 2012-12-11
MX2010004045A (es) 2010-07-06
WO2009051398A3 (en) 2009-06-04
ES2622703T3 (es) 2017-07-07
KR101542921B1 (ko) 2015-08-11
CA2702461C (en) 2012-12-11
US20100240662A1 (en) 2010-09-23
CN101827849A (zh) 2010-09-08
EP2212328B1 (en) 2017-01-25
PL2212330T3 (pl) 2015-09-30
US8071764B2 (en) 2011-12-06
US7671054B1 (en) 2010-03-02
WO2009051398A2 (en) 2009-04-23

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