PL2235002T3 - Związki 4-pirydynonu i ich zastosowanie w raku - Google Patents

Związki 4-pirydynonu i ich zastosowanie w raku

Info

Publication number
PL2235002T3
PL2235002T3 PL09704457T PL09704457T PL2235002T3 PL 2235002 T3 PL2235002 T3 PL 2235002T3 PL 09704457 T PL09704457 T PL 09704457T PL 09704457 T PL09704457 T PL 09704457T PL 2235002 T3 PL2235002 T3 PL 2235002T3
Authority
PL
Poland
Prior art keywords
cancer
pyridinone compounds
pyridinone
compounds
Prior art date
Application number
PL09704457T
Other languages
English (en)
Inventor
Robert M Borzilleri
Zhen-Wei Cai
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PL2235002T3 publication Critical patent/PL2235002T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL09704457T 2008-01-23 2009-01-22 Związki 4-pirydynonu i ich zastosowanie w raku PL2235002T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2284808P 2008-01-23 2008-01-23
PCT/US2009/031649 WO2009094417A1 (en) 2008-01-23 2009-01-22 4-pyridinone compounds and their use for cancer
EP09704457A EP2235002B1 (en) 2008-01-23 2009-01-22 4-pyridinone compounds and their use for cancer

Publications (1)

Publication Number Publication Date
PL2235002T3 true PL2235002T3 (pl) 2013-04-30

Family

ID=40637826

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09704457T PL2235002T3 (pl) 2008-01-23 2009-01-22 Związki 4-pirydynonu i ich zastosowanie w raku

Country Status (21)

Country Link
US (2) US8124768B2 (pl)
EP (1) EP2235002B1 (pl)
JP (1) JP5314050B2 (pl)
KR (1) KR101596527B1 (pl)
CN (1) CN101977906B (pl)
AU (1) AU2009206440B2 (pl)
BR (1) BRPI0906444B8 (pl)
CA (1) CA2713111C (pl)
CO (1) CO6230986A2 (pl)
CY (1) CY1114140T1 (pl)
DK (1) DK2235002T3 (pl)
EA (1) EA017736B1 (pl)
ES (1) ES2398335T3 (pl)
HR (1) HRP20130040T1 (pl)
IL (1) IL207212A (pl)
NZ (1) NZ586630A (pl)
PL (1) PL2235002T3 (pl)
PT (1) PT2235002E (pl)
SI (1) SI2235002T1 (pl)
WO (1) WO2009094417A1 (pl)
ZA (1) ZA201005248B (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2599458T3 (es) 2008-10-14 2017-02-01 Sunshine Lake Pharma Co., Ltd. Compuestos y métodos de uso
EP2408300B1 (en) 2009-03-21 2016-05-11 Sunshine Lake Pharma Co., Ltd. Amino ester derivatives, salts thereof and methods of use
CA2800998A1 (en) 2010-04-29 2011-11-10 Deciphera Pharmaceuticals, Llc Pyridone amides and analogs exhibiting anti-cancer and anti-proliferative activities
RU2477723C2 (ru) 2011-06-16 2013-03-20 Общество С Ограниченной Ответственностью "Фьюжн Фарма" Ингибиторы протеинкиназ (варианты), их применение для лечения онкологических заболеваний и фармацевтическая композиция на их основе
DK2810937T3 (en) 2012-01-31 2017-03-13 Daiichi Sankyo Co Ltd PYRIDONE DERIVATIVES
JP6342392B2 (ja) 2012-07-28 2018-06-13 カリター・サイエンシーズ・エルエルシー 置換型ピラゾロン化合物及び使用方法
US8975282B2 (en) 2012-07-28 2015-03-10 Sunshine Lake Pharma Co., Ltd. Substituted pyrazolone compounds and methods of use
US9102624B2 (en) * 2012-08-23 2015-08-11 Boehringer Ingelheim International Gmbh Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
US20140057926A1 (en) * 2012-08-23 2014-02-27 Boehringer Ingelheim International Gmbh Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
US20140057920A1 (en) * 2012-08-23 2014-02-27 Boehringer Ingelheim International Gmbh Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
TWI723572B (zh) 2014-07-07 2021-04-01 日商第一三共股份有限公司 具有四氫吡喃基甲基之吡啶酮衍生物及其用途
CN105153026B (zh) * 2015-08-21 2018-02-02 江西科技师范大学 含联芳基酰胺结构的索拉非尼衍生物及其制备方法和应用
CA3125559A1 (en) * 2019-01-03 2020-07-09 Array Biopharma Inc. Quinoline compounds as inhibitors of tam and met kinases
KR20220170766A (ko) * 2021-06-22 2022-12-30 주식회사 엘지화학 단백질 키나아제 억제제로서의 신규한 화합물
TW202315628A (zh) * 2021-06-24 2023-04-16 南韓商Ｌｇ化學股份有限公司 作為ｒｏｎ抑制劑之新穎吡啶衍生物化合物
WO2024067783A1 (zh) * 2022-09-28 2024-04-04 上海济煜医药科技有限公司 含磷类化合物及其制备方法和医药应用

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EP0430885A3 (en) 1989-12-01 1991-11-06 Ciba-Geigy Ag Anthelmintical compounds
EP0860433B1 (en) 1995-11-07 2002-07-03 Kirin Beer Kabushiki Kaisha Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of growth factor receptor originating in platelet and pharmaceutical compositions containing the same
CA2333554A1 (en) * 1998-06-17 1999-12-23 Chu-Baio Xue Cyclic hydroxamic acids as metalloproteinase inhibitors
ES2546386T3 (es) * 1999-07-20 2015-09-23 Dow Agrosciences, Llc Amidas aromáticas heterocíclicas fungicidas y sus composiciones, métodos de uso y preparación
US6355660B1 (en) * 1999-07-20 2002-03-12 Dow Agrosciences Llc Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
CA2384291A1 (en) 1999-09-21 2001-03-29 Astrazeneca Ab Quinazoline derivatives and their use as pharmaceuticals
US6498151B2 (en) * 2000-03-22 2002-12-24 Merck Frosst Canada & Co. Aryldifluoromethylphosphonic acids with sulfur-containing substituents as PTP-1B inhibitors
FR2812633A1 (fr) * 2000-08-04 2002-02-08 Aventis Cropscience Sa Derives de phenyl(thio)urees et phenyl(thio)carbamates fongicides
SE0102384D0 (sv) * 2001-07-03 2001-07-03 Pharmacia Ab New compounds
US20050038035A1 (en) * 2001-11-28 2005-02-17 Hisashi Takasugi Heterocyclic amide compounds as apolipoprotein b inhibitors
SE0302487D0 (sv) 2003-09-18 2003-09-18 Astrazeneca Ab Novel compounds
JP4829506B2 (ja) * 2004-02-17 2011-12-07 石原産業株式会社 チオアミド系化合物又はその塩、並びにそれらを含有するサイトカイン産生抑制剤
US7459562B2 (en) * 2004-04-23 2008-12-02 Bristol-Myers Squibb Company Monocyclic heterocycles as kinase inhibitors
CA2564355C (en) * 2004-05-07 2012-07-03 Amgen Inc. Protein kinase modulators and method of use
US7173031B2 (en) * 2004-06-28 2007-02-06 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
US7432373B2 (en) * 2004-06-28 2008-10-07 Bristol-Meyers Squibb Company Processes and intermediates useful for preparing fused heterocyclic kinase inhibitors
US7439246B2 (en) * 2004-06-28 2008-10-21 Bristol-Myers Squibb Company Fused heterocyclic kinase inhibitors
JO2787B1 (en) 2005-04-27 2014-03-15 امجين إنك, Alternative amide derivatives and methods of use
WO2007033196A1 (en) * 2005-09-14 2007-03-22 Bristol-Myers Squibb Company Met kinase inhibitors
US7880004B2 (en) * 2005-09-15 2011-02-01 Bristol-Myers Squibb Company Met kinase inhibitors
US7348325B2 (en) * 2005-11-30 2008-03-25 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
JP5693239B2 (ja) 2008-01-23 2015-04-01 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ ４−ピリジノン化合物および癌についてのその使用

Also Published As

Publication number Publication date
US20120114643A1 (en) 2012-05-10
JP2011510087A (ja) 2011-03-31
AU2009206440B2 (en) 2013-08-15
SI2235002T1 (sl) 2013-06-28
ZA201005248B (en) 2011-09-28
EA201001196A1 (ru) 2011-02-28
PT2235002E (pt) 2013-01-30
HK1143157A1 (en) 2010-12-24
IL207212A0 (en) 2010-12-30
AU2009206440A1 (en) 2009-07-30
DK2235002T3 (da) 2013-03-11
BRPI0906444A2 (pt) 2015-07-14
ES2398335T3 (es) 2013-03-15
CA2713111C (en) 2015-06-30
IL207212A (en) 2015-01-29
CN101977906B (zh) 2014-11-05
US8258118B2 (en) 2012-09-04
BRPI0906444A8 (pt) 2020-02-27
WO2009094417A1 (en) 2009-07-30
EA017736B1 (ru) 2013-02-28
CA2713111A1 (en) 2009-07-30
BRPI0906444B8 (pt) 2021-05-25
JP5314050B2 (ja) 2013-10-16
NZ586630A (en) 2011-12-22
BRPI0906444B1 (pt) 2021-03-16
HRP20130040T1 (hr) 2013-02-28
KR101596527B1 (ko) 2016-02-22
US8124768B2 (en) 2012-02-28
CY1114140T1 (el) 2016-07-27
EP2235002A1 (en) 2010-10-06
CN101977906A (zh) 2011-02-16
EP2235002B1 (en) 2012-11-21
CO6230986A2 (es) 2010-12-20
KR20100103636A (ko) 2010-09-27
US20110034416A1 (en) 2011-02-10

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