PL2263694T3 - Środek przeciwnowotworowy zawierający FK228 jako inhibitor deacetylazy histonowej i doksorubicynę jako inhibitor topoizomerazy II - Google Patents

Środek przeciwnowotworowy zawierający FK228 jako inhibitor deacetylazy histonowej i doksorubicynę jako inhibitor topoizomerazy II

Info

Publication number: PL2263694T3
Authority: PL; Poland
Prior art keywords: inhibitor; topoisomerase; histone deacetylase; doxorubicin; antitumor agent
Prior art date: 2003-09-25

Application number

PL10163527T

Other languages

English (en)

Inventor

Yoshinori Naoe

Yuka Sasakawa

Original Assignee

Astellas Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-09-25

Filing date

2004-09-24

Publication date

2013-11-29

2004-09-24 Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc

2013-11-29 Publication of PL2263694T3 publication Critical patent/PL2263694T3/pl

Links

229940124087 DNA topoisomerase II inhibitor Drugs 0.000 title abstract 2
239000000317 Topoisomerase II Inhibitor Substances 0.000 title abstract 2
AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 title 2
239000002246 antineoplastic agent Substances 0.000 title 1
229960004679 doxorubicin Drugs 0.000 title 1
229940121372 histone deacetylase inhibitor Drugs 0.000 title 1
239000003276 histone deacetylase inhibitor Substances 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 2
206010028980 Neoplasm Diseases 0.000 abstract 1
VJZITPJGSQKZMX-XDPRQOKASA-N amrubicin Chemical compound O([C@H]1C[C@](CC2=C(O)C=3C(=O)C4=CC=CC=C4C(=O)C=3C(O)=C21)(N)C(=O)C)[C@H]1C[C@H](O)[C@H](O)CO1 VJZITPJGSQKZMX-XDPRQOKASA-N 0.000 abstract 1
229960002550 amrubicin Drugs 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Compounds Of Unknown Constitution (AREA)

PL10163527T 2003-09-25 2004-09-24 Środek przeciwnowotworowy zawierający FK228 jako inhibitor deacetylazy histonowej i doksorubicynę jako inhibitor topoizomerazy II PL2263694T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP2003334340		2003-09-25
JP2003344315		2003-10-02
EP10163527.4A EP2263694B1 (en)	2003-09-25	2004-09-24	Antitumor agent comprising the histone deacetylase inhibitor FK228 and the topoisomerase II inhibitor doxorubicin
EP04773539A EP1670514B1 (en)	2003-09-25	2004-09-24	Antitumor agent comprising a histone deacetylase inhibitor and a topoisomerase ii inhibitor

Publications (1)

Publication Number	Publication Date
PL2263694T3 true PL2263694T3 (pl)	2013-11-29

Family

ID=34380371

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL04773539T PL1670514T3 (pl)	2003-09-25	2004-09-24	Środek przeciwnowotworowy zawierający inhibitor deacetylazy histonowej i inhibitor topoizomerazy II
PL10163527T PL2263694T3 (pl)	2003-09-25	2004-09-24	Środek przeciwnowotworowy zawierający FK228 jako inhibitor deacetylazy histonowej i doksorubicynę jako inhibitor topoizomerazy II

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PL04773539T PL1670514T3 (pl)	2003-09-25	2004-09-24	Środek przeciwnowotworowy zawierający inhibitor deacetylazy histonowej i inhibitor topoizomerazy II

Country Status (14)

Country	Link
US (1)	US7314862B2 (pl)
EP (2)	EP1670514B1 (pl)
JP (1)	JP4779971B2 (pl)
AT (1)	ATE471740T1 (pl)
CA (1)	CA2540108A1 (pl)
CY (1)	CY1114359T1 (pl)
DE (1)	DE602004027824D1 (pl)
DK (1)	DK2263694T3 (pl)
ES (2)	ES2425083T3 (pl)
MX (1)	MXPA06003222A (pl)
PL (2)	PL1670514T3 (pl)
PT (1)	PT2263694E (pl)
SI (1)	SI2263694T1 (pl)
WO (1)	WO2005030239A2 (pl)

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2004
- 2004-09-24 ES ES10163527T patent/ES2425083T3/es not_active Expired - Lifetime
- 2004-09-24 EP EP04773539A patent/EP1670514B1/en not_active Expired - Lifetime
- 2004-09-24 ES ES04773539T patent/ES2344899T3/es not_active Expired - Lifetime
- 2004-09-24 CA CA002540108A patent/CA2540108A1/en not_active Abandoned
- 2004-09-24 PT PT101635274T patent/PT2263694E/pt unknown
- 2004-09-24 MX MXPA06003222A patent/MXPA06003222A/es active IP Right Grant
- 2004-09-24 SI SI200432064T patent/SI2263694T1/sl unknown
- 2004-09-24 EP EP10163527.4A patent/EP2263694B1/en not_active Expired - Lifetime
- 2004-09-24 PL PL04773539T patent/PL1670514T3/pl unknown
- 2004-09-24 DK DK10163527.4T patent/DK2263694T3/da active
- 2004-09-24 PL PL10163527T patent/PL2263694T3/pl unknown
- 2004-09-24 JP JP2006515402A patent/JP4779971B2/ja not_active Expired - Lifetime
- 2004-09-24 AT AT04773539T patent/ATE471740T1/de active
- 2004-09-24 US US10/948,288 patent/US7314862B2/en not_active Expired - Lifetime
- 2004-09-24 DE DE602004027824T patent/DE602004027824D1/de not_active Expired - Lifetime
- 2004-09-24 WO PCT/JP2004/014451 patent/WO2005030239A2/en not_active Ceased
2013
- 2013-09-09 CY CY20131100771T patent/CY1114359T1/el unknown

Also Published As

Publication number	Publication date
ATE471740T1 (de)	2010-07-15
PL1670514T3 (pl)	2010-11-30
CA2540108A1 (en)	2005-04-07
US7314862B2 (en)	2008-01-01
EP2263694A1 (en)	2010-12-22
EP1670514B1 (en)	2010-06-23
ES2344899T3 (es)	2010-09-09
CY1114359T1 (el)	2016-08-31
US20050070467A1 (en)	2005-03-31
ES2425083T3 (es)	2013-10-11
JP2007506647A (ja)	2007-03-22
MXPA06003222A (es)	2006-05-22
PT2263694E (pt)	2013-08-27
DK2263694T3 (da)	2013-08-26
EP1670514A2 (en)	2006-06-21
DE602004027824D1 (de)	2010-08-05
SI2263694T1 (sl)	2013-09-30
WO2005030239A3 (en)	2005-07-28
WO2005030239A2 (en)	2005-04-07
JP4779971B2 (ja)	2011-09-28
EP2263694B1 (en)	2013-06-12

Publication	Publication Date	Title
SI2263694T1 (sl)	2013-09-30	Antitumorsko sredstvo, ki obsega inhibitor histon-deacetilaze FK228 in inhibitor topoizomeraze II doksorubicin
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