PL2346837T3 - Sposoby wytwarzania pochodnych chinazolinonu - Google Patents

Sposoby wytwarzania pochodnych chinazolinonu

Info

Publication number
PL2346837T3
PL2346837T3 PL09770937T PL09770937T PL2346837T3 PL 2346837 T3 PL2346837 T3 PL 2346837T3 PL 09770937 T PL09770937 T PL 09770937T PL 09770937 T PL09770937 T PL 09770937T PL 2346837 T3 PL2346837 T3 PL 2346837T3
Authority
PL
Poland
Prior art keywords
methods
quinazolinone derivatives
preparing quinazolinone
preparing
derivatives
Prior art date
Application number
PL09770937T
Other languages
English (en)
Inventor
Henrik C Hansen
Shubham P Chopade
Janakiram R Citineni
Robert P Short
George P Yiannikouros
Original Assignee
Resverlogix Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Resverlogix Corp filed Critical Resverlogix Corp
Publication of PL2346837T3 publication Critical patent/PL2346837T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL09770937T 2008-06-26 2009-06-24 Sposoby wytwarzania pochodnych chinazolinonu PL2346837T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7595208P 2008-06-26 2008-06-26
PCT/US2009/048457 WO2009158404A1 (en) 2008-06-26 2009-06-24 Methods of preparing quinazolinone derivatives
EP09770937.2A EP2346837B8 (en) 2008-06-26 2009-06-24 Methods of preparing quinazolinone derivatives

Publications (1)

Publication Number Publication Date
PL2346837T3 true PL2346837T3 (pl) 2015-07-31

Family

ID=40852111

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09770937T PL2346837T3 (pl) 2008-06-26 2009-06-24 Sposoby wytwarzania pochodnych chinazolinonu

Country Status (18)

Country Link
US (1) US8114995B2 (pl)
EP (1) EP2346837B8 (pl)
JP (1) JP5602728B2 (pl)
KR (1) KR101629356B1 (pl)
CN (1) CN101970416B (pl)
AU (1) AU2009262252B2 (pl)
CA (1) CA2711103C (pl)
CY (1) CY1116260T1 (pl)
DK (1) DK2346837T3 (pl)
ES (1) ES2532402T3 (pl)
HR (1) HRP20150477T8 (pl)
IL (1) IL206544A (pl)
NZ (1) NZ586440A (pl)
PL (1) PL2346837T3 (pl)
PT (1) PT2346837E (pl)
RU (1) RU2520098C2 (pl)
SI (1) SI2346837T1 (pl)
WO (1) WO2009158404A1 (pl)

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ES2542835T3 (es) 2009-01-08 2015-08-12 Resverlogix Corporation Compuestos para la prevención y el tratamiento de enfermedades cardiovasculares
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US9757368B2 (en) 2009-04-22 2017-09-12 Resverlogix Corp. Anti-inflammatory agents
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PT2773354T (pt) 2011-11-01 2019-07-17 Resverlogix Corp Formulações orais de libertação imediata para quinazolinonas substituídas
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CA3014644A1 (en) 2016-02-15 2017-08-24 The Regents Of The University Of Michigan Fused 1,4-oxazepines and related analogs as bet bromodomain inhibitors
CN106008372B (zh) * 2016-03-16 2019-01-15 江苏悦兴药业有限公司 一种达克米替尼的制备方法及其关键中间体
AU2017246452C1 (en) 2016-04-06 2021-06-03 The Regents Of The University Of Michigan MDM2 protein degraders
EP3440082A1 (en) 2016-04-06 2019-02-13 The Regents of The University of Michigan Monofunctional intermediates for ligand-dependent target protein degradation
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JP6849804B2 (ja) * 2016-12-09 2021-03-31 クリスタル ファーマシューティカル(スーチョウ)カンパニー,リミテッド ブロモドメインタンパク質阻害薬の結晶形及びその製造方法並びに用途
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US11267822B2 (en) 2017-09-13 2022-03-08 The Regents Of The University Of Michigan BET bromodomain protein degraders with cleavable linkers
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