PL2714006T3 - Donosowe bio-adhezyjne formulacje żelu testosteronowego i ich zastosowanie w leczeniu hipogonadyzmu - Google Patents

Donosowe bio-adhezyjne formulacje żelu testosteronowego i ich zastosowanie w leczeniu hipogonadyzmu

Info

Publication number: PL2714006T3
Authority: PL; Poland
Prior art keywords: hypogonadism; nasal; bio; adhesive; treatment
Prior art date: 2011-05-15

Application number

PL12748245T

Other languages

English (en)

Other versions

PL2714006T4 (pl

Inventor

Wayne KREPPNER

Siobhan Fogarty

Werner Oberegger

Paul José Pierre Marie Maes

Original Assignee

Acerus Biopharma Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-05-15

Filing date

2012-05-15

Publication date

2021-08-16

2012-05-15 Application filed by Acerus Biopharma Inc. filed Critical Acerus Biopharma Inc.

2021-08-16 Publication of PL2714006T4 publication Critical patent/PL2714006T4/pl

2021-08-16 Publication of PL2714006T3 publication Critical patent/PL2714006T3/pl

Links

MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 title 2
206010058359 Hypogonadism Diseases 0.000 title 1
239000000227 bioadhesive Substances 0.000 title 1
238000009472 formulation Methods 0.000 title 1
239000000203 mixture Substances 0.000 title 1
229960003604 testosterone Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Inorganic Chemistry (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Oil, Petroleum & Natural Gas (AREA)
Otolaryngology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biomedical Technology (AREA)
Pregnancy & Childbirth (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Anesthesiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL12748245T 2011-05-15 2012-05-15 Donosowe bio-adhezyjne formulacje żelu testosteronowego i ich zastosowanie w leczeniu hipogonadyzmu PL2714006T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201161486324P	2011-05-15	2011-05-15
US201161486634P	2011-05-16	2011-05-16
PCT/IB2012/001112 WO2012156820A1 (en)	2011-05-15	2012-05-15	Intranasal testosterone bio-adhesive gel formulations and use thereof for treating male hypogonadism
EP12748245.3A EP2714006B1 (en)	2011-05-15	2012-05-15	Intranasal testosterone bio-adhesive gel formulations and use thereof for treating male hypogonadism

Publications (2)

Publication Number	Publication Date
PL2714006T4 PL2714006T4 (pl)	2021-08-16
PL2714006T3 true PL2714006T3 (pl)	2021-08-16

Family

ID=46579248

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL12748245T PL2714006T3 (pl)	2011-05-15	2012-05-15	Donosowe bio-adhezyjne formulacje żelu testosteronowego i ich zastosowanie w leczeniu hipogonadyzmu

Country Status (16)

Country	Link
EP (3)	EP3977982A1 (pl)
JP (9)	JP2014513716A (pl)
KR (10)	KR20190117803A (pl)
CN (4)	CN103813784A (pl)
AR (2)	AR086409A1 (pl)
AU (11)	AU2012257492A1 (pl)
BR (2)	BR112013029336B1 (pl)
CA (3)	CA2836405C (pl)
DK (1)	DK2714006T3 (pl)
EA (1)	EA201391701A1 (pl)
ES (1)	ES2859784T3 (pl)
IL (2)	IL229401A0 (pl)
MX (4)	MX363561B (pl)
PL (1)	PL2714006T3 (pl)
WO (2)	WO2012156822A1 (pl)
ZA (2)	ZA201309265B (pl)

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US20130045958A1 (en)	2011-05-13	2013-02-21	Trimel Pharmaceuticals Corporation	Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
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2012
- 2012-05-15 KR KR1020197029484A patent/KR20190117803A/ko not_active Ceased
- 2012-05-15 ES ES12748245T patent/ES2859784T3/es active Active
- 2012-05-15 EA EA201391701A patent/EA201391701A1/ru unknown
- 2012-05-15 KR KR1020137033180A patent/KR20140033408A/ko not_active Ceased
- 2012-05-15 KR KR1020187038088A patent/KR102088038B1/ko active Active
- 2012-05-15 CN CN201280035162.8A patent/CN103813784A/zh active Pending
- 2012-05-15 AU AU2012257492A patent/AU2012257492A1/en not_active Abandoned
- 2012-05-15 DK DK12748245.3T patent/DK2714006T3/da active
- 2012-05-15 KR KR1020217007047A patent/KR102568894B1/ko active Active
- 2012-05-15 EP EP21191386.8A patent/EP3977982A1/en not_active Withdrawn
- 2012-05-15 MX MX2013013388A patent/MX363561B/es unknown
- 2012-05-15 MX MX2013013369A patent/MX2013013369A/es unknown
- 2012-05-15 KR KR1020207006630A patent/KR20200028503A/ko not_active Ceased
- 2012-05-15 CA CA2836405A patent/CA2836405C/en active Active
- 2012-05-15 CN CN201811198846.5A patent/CN109481394B/zh active Active
- 2012-05-15 EP EP12738595.3A patent/EP2709588B1/en active Active
- 2012-05-15 JP JP2014510900A patent/JP2014513716A/ja active Pending
- 2012-05-15 MX MX2020008599A patent/MX395212B/es unknown
- 2012-05-15 JP JP2014510901A patent/JP6152092B2/ja not_active Expired - Fee Related
- 2012-05-15 KR KR1020137033181A patent/KR20140045400A/ko not_active Ceased
- 2012-05-15 BR BR112013029336-5A patent/BR112013029336B1/pt active IP Right Grant
- 2012-05-15 BR BR112013029332-2A patent/BR112013029332A2/pt not_active Application Discontinuation
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Also Published As

Publication number	Publication date
JP2020079257A (ja)	2020-05-28
AU2020210227A1 (en)	2020-08-20
CA2836398A1 (en)	2012-11-22
AU2019201618A1 (en)	2019-04-18
KR20230041081A (ko)	2023-03-23
JP6594924B2 (ja)	2019-10-23
IL229400A0 (en)	2014-01-30
JP2022105175A (ja)	2022-07-12
KR102088038B1 (ko)	2020-03-13
ES2859784T3 (es)	2021-10-04
MX374398B (es)	2025-03-06
ZA201309265B (en)	2016-01-27
BR112013029336B1 (pt)	2021-11-30
EP3977982A1 (en)	2022-04-06
AU2012257490A1 (en)	2013-12-19
PL2714006T4 (pl)	2021-08-16
IL229401A0 (en)	2014-01-30
AR086409A1 (es)	2013-12-11
AU2012257492A1 (en)	2013-12-19
CA2836405A1 (en)	2012-11-22
CN103813784A (zh)	2014-05-21
JP2020073469A (ja)	2020-05-14
AU2020267162A1 (en)	2020-12-03
WO2012156820A1 (en)	2012-11-22
CN103796636A (zh)	2014-05-14
KR102568894B1 (ko)	2023-08-21
KR20140033408A (ko)	2014-03-18
CN109481394A (zh)	2019-03-19
CA2836398C (en)	2021-12-14
EP2709588B1 (en)	2021-08-25
WO2012156820A9 (en)	2014-02-20
AU2020267162B2 (en)	2022-06-09
CN109481394B (zh)	2023-05-05
KR20200028503A (ko)	2020-03-16
JP2022078222A (ja)	2022-05-24
CN103796636B (zh)	2019-04-05
CA3034552C (en)	2023-02-07
CA2836405C (en)	2021-09-07
DK2714006T3 (da)	2021-03-15
MX2019003340A (es)	2019-07-04
AU2017203470A1 (en)	2017-06-22
KR20240162608A (ko)	2024-11-15
AU2019203400A1 (en)	2019-08-01
BR112013029332A2 (pt)	2021-06-01
BR112013029336A2 (pt)	2020-08-11
JP2021001206A (ja)	2021-01-07
AU2017204182A1 (en)	2017-07-20
JP2018199701A (ja)	2018-12-20
JP2014515038A (ja)	2014-06-26
MX2013013369A (es)	2014-10-17
EA201391701A1 (ru)	2014-04-30
MX363561B (es)	2019-03-27
EP2714006B1 (en)	2020-12-09
EP2714006A1 (en)	2014-04-09
WO2012156822A1 (en)	2012-11-22
JP7017254B2 (ja)	2022-02-08
KR20140045400A (ko)	2014-04-16
KR20200118228A (ko)	2020-10-14
JP2014513716A (ja)	2014-06-05
CA3034552A1 (en)	2012-11-22
CN110613679A (zh)	2019-12-27
ZA201309264B (en)	2015-09-30
JP2017160204A (ja)	2017-09-14
AU2019203067A1 (en)	2019-05-23
AU2022202402A1 (en)	2022-05-12
MX2020008599A (es)	2022-08-31
EP2709588A1 (en)	2014-03-26
KR20190117803A (ko)	2019-10-16
MX2013013388A (es)	2014-09-15
AR089553A1 (es)	2014-09-03
AU2024216312A1 (en)	2024-10-24
JP6152092B2 (ja)	2017-06-28
KR20210135003A (ko)	2021-11-11
KR20210029849A (ko)	2021-03-16
KR20190006194A (ko)	2019-01-17
MX395212B (es)	2025-03-21

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