PL2915813T3 - Antybiotyki oksazolidynonowe - Google Patents

Antybiotyki oksazolidynonowe

Info

Publication number
PL2915813T3
PL2915813T3 PL15154086T PL15154086T PL2915813T3 PL 2915813 T3 PL2915813 T3 PL 2915813T3 PL 15154086 T PL15154086 T PL 15154086T PL 15154086 T PL15154086 T PL 15154086T PL 2915813 T3 PL2915813 T3 PL 2915813T3
Authority
PL
Poland
Prior art keywords
oxazolidinone antibiotics
oxazolidinone
antibiotics
Prior art date
Application number
PL15154086T
Other languages
English (en)
Inventor
Daniel Bur
Christian Hubschwerlen
Georg Rueedi
Jean-Philippe Surivet
Cornelia Zumbrunn
Original Assignee
Actelion Pharmaceuticals Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd. filed Critical Actelion Pharmaceuticals Ltd.
Publication of PL2915813T3 publication Critical patent/PL2915813T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL15154086T 2007-04-11 2008-04-11 Antybiotyki oksazolidynonowe PL2915813T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IB2007051290 2007-04-11
IB2007054587 2007-11-12
IB2007054768 2007-11-23
EP15154086.1A EP2915813B1 (en) 2007-04-11 2008-04-11 Oxazolidinone antibiotics

Publications (1)

Publication Number Publication Date
PL2915813T3 true PL2915813T3 (pl) 2017-07-31

Family

ID=39682545

Family Applications (3)

Application Number Title Priority Date Filing Date
PL15154086T PL2915813T3 (pl) 2007-04-11 2008-04-11 Antybiotyki oksazolidynonowe
PL08737800T PL2144910T3 (pl) 2007-04-11 2008-04-11 Antybiotyki oksazolidynonowe
PL15154003T PL2905283T3 (pl) 2007-04-11 2008-04-11 Pochodne oksazolidynonu

Family Applications After (2)

Application Number Title Priority Date Filing Date
PL08737800T PL2144910T3 (pl) 2007-04-11 2008-04-11 Antybiotyki oksazolidynonowe
PL15154003T PL2905283T3 (pl) 2007-04-11 2008-04-11 Pochodne oksazolidynonu

Country Status (16)

Country Link
US (1) US8217029B2 (pl)
EP (3) EP2905283B1 (pl)
JP (1) JP5427770B2 (pl)
KR (1) KR101495269B1 (pl)
CN (3) CN102746297B (pl)
AR (1) AR066013A1 (pl)
AU (1) AU2008238904B2 (pl)
BR (1) BRPI0809977A8 (pl)
CA (3) CA2876878C (pl)
CL (1) CL2008001002A1 (pl)
ES (3) ES2618492T3 (pl)
MX (3) MX351590B (pl)
PL (3) PL2915813T3 (pl)
RU (1) RU2470022C2 (pl)
TW (1) TWI411434B (pl)
WO (1) WO2008126034A2 (pl)

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ES2411930T3 (es) 2008-02-20 2013-07-09 Actelion Pharmaceuticals Ltd. Compuestos antibióticos azatricíclicos
JP5404652B2 (ja) 2008-02-22 2014-02-05 アクテリオン ファーマシューティカルズ リミテッド オキサゾリジノン誘導体
EP2321307B1 (en) 2008-08-04 2012-12-19 Actelion Pharmaceuticals Ltd. Tricyclic alkylaminomethyloxazolidinone derivatives
KR101294962B1 (ko) 2008-10-07 2013-08-12 액테리온 파마슈티칼 리미티드 트리사이클 옥사졸리디논 항생제 화합물
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EP2388260A1 (de) * 2010-05-21 2011-11-23 Archimica GmbH Herstellungsverfahren für einen Inhibitor eines Blutgerinnungsfaktors
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CA2842885A1 (en) 2011-08-11 2013-02-14 Actelion Pharmaceuticals Ltd Quinazoline-2,4-dione derivatives
JP6030146B2 (ja) 2011-11-08 2016-11-24 アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd 2−オキソ−オキサゾリジン−3,5−ジイル抗生物質誘導体
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AU2013277154A1 (en) 2012-06-20 2014-12-18 Jonathan E. Grob Complement pathway modulators and uses thereof
WO2014024056A1 (en) 2012-08-06 2014-02-13 Daiichi Sankyo Company, Limited Pyrrolidine derivatives with antibacterial properties
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AR095079A1 (es) 2013-03-12 2015-09-16 Hoffmann La Roche Derivados de octahidro-pirrolo[3,4-c]-pirrol y piridina-fenilo
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EP3122751B1 (en) 2014-03-26 2019-10-30 F.Hoffmann-La Roche Ag Condensed [1,4]diazepine compounds as autotaxin (atx) and lysophosphatidic acid (lpa) production inhibitors
MA39792B1 (fr) 2014-03-26 2019-12-31 Hoffmann La Roche Composés bicycliques en tant qu'inhibiteurs de production d'autotaxine (atx) et d'acide lysophosphatidique (lpa)
AR102256A1 (es) * 2014-10-15 2017-02-15 Actelion Pharmaceuticals Ltd Derivados biaromáticos básicos antibacterianos con sustitución de aminoalcoxi
MA41168A (fr) 2014-12-17 2017-10-24 Acraf Nouveaux composés antibactériens
MA41898A (fr) 2015-04-10 2018-02-13 Hoffmann La Roche Dérivés de quinazolinone bicyclique
MX387736B (es) 2015-09-04 2025-03-18 Hoffmann La Roche Derivados de fenoximetilo.
KR20180054634A (ko) 2015-09-24 2018-05-24 에프. 호프만-라 로슈 아게 이중 오토탁신(atx)/탄산 무수화효소(ca) 억제제로서 신규한 이환형 화합물
PE20180451A1 (es) 2015-09-24 2018-03-05 Hoffmann La Roche Nuevos compuestos biciclicos como inhibidores de atx
MX2017015034A (es) 2015-09-24 2018-04-13 Hoffmann La Roche Nuevos compuestos biciclicos como inhibidores duales de autotaxina (atx)/anhidrasa carbonica (ca).
CN107635995B (zh) 2015-09-24 2022-08-19 豪夫迈·罗氏有限公司 作为atx抑制剂的二环化合物
HUE060536T2 (hu) 2015-12-10 2023-03-28 Bracco Imaging Spa Dimer kontrasztanyagok
CN108290849B (zh) 2015-12-10 2022-03-22 伯拉考成像股份公司 造影剂
MX2021006804A (es) 2015-12-17 2023-01-13 Merck Patent Gmbh Antagonistas policiclicos del receptor 7/8 tipo toll (tlr7/8) y uso de los mismos en el tratamiento de trastornos inmunitarios.
GB201602235D0 (en) * 2016-02-08 2016-03-23 Redx Pharma Plc Antibacterial compounds
EP3414246A1 (en) * 2016-02-08 2018-12-19 Redx Pharma PLC Antibacterial compounds
US10487093B2 (en) 2016-02-08 2019-11-26 Redx Pharma Plc Heterocyclic compounds, in particular 2-oxo-4,4,5,5,6,6,7,7-octahydrobenzoxazole derivatives, and their use as antibacterial compounds
WO2017178301A1 (en) 2016-04-13 2017-10-19 Bracco Imaging Spa Contrast agents
EP4198031A1 (en) 2016-08-08 2023-06-21 Merck Patent GmbH Tlr7/8 antagonists and uses thereof
EP3551614B1 (en) 2016-12-12 2021-08-25 Bracco Imaging SpA Dimeric contrast agents
TW201833120A (zh) 2017-02-17 2018-09-16 瑞士商愛杜西亞製藥有限公司 芳基噁唑啶酮抗生素化合物
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CN110382484B (zh) 2017-03-16 2022-12-06 豪夫迈·罗氏有限公司 新的作为atx抑制剂的二环化合物
WO2019018354A1 (en) * 2017-07-18 2019-01-24 Merck Patent Gmbh ANTAGONISTS OF TLR7 / 8 AND USES THEREOF
WO2019106693A1 (en) * 2017-11-29 2019-06-06 Bugworks Research India Pvt Ltd Anti-bacterial heterocyclic compounds and their synthesis
CN109265389B (zh) * 2018-08-31 2020-08-18 南京富润凯德生物医药有限公司 2-(氨基甲基)-1-氧杂-7-氮杂螺[3.5]壬烷衍生物、中间体及其制备方法

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Also Published As

Publication number Publication date
EP2905283A1 (en) 2015-08-12
JP2010523646A (ja) 2010-07-15
AU2008238904B2 (en) 2013-11-28
WO2008126034A3 (en) 2008-12-31
WO2008126034A2 (en) 2008-10-23
KR20090130086A (ko) 2009-12-17
ES2618492T3 (es) 2017-06-21
CA2876878C (en) 2017-07-11
MX351589B (es) 2017-10-20
PL2144910T3 (pl) 2016-04-29
PL2905283T3 (pl) 2017-06-30
TW200848031A (en) 2008-12-16
CA2679071A1 (en) 2008-10-23
CN102746297B (zh) 2015-08-26
US20110039823A1 (en) 2011-02-17
ES2557172T3 (es) 2016-01-22
BRPI0809977A2 (pt) 2014-10-07
CA2876879A1 (en) 2008-10-23
EP2915813A1 (en) 2015-09-09
AR066013A1 (es) 2009-07-15
CA2876878A1 (en) 2008-10-23
US8217029B2 (en) 2012-07-10
CL2008001002A1 (es) 2008-10-17
AU2008238904A1 (en) 2008-10-23
RU2009141311A (ru) 2011-05-20
MX351590B (es) 2017-10-20
EP2144910A2 (en) 2010-01-20
CN102746296A (zh) 2012-10-24
CA2876879C (en) 2017-11-28
JP5427770B2 (ja) 2014-02-26
ES2622961T3 (es) 2017-07-10
MX2009010642A (es) 2009-10-22
EP2915813B1 (en) 2017-02-01
TWI411434B (zh) 2013-10-11
CN102746297A (zh) 2012-10-24
CN101679415B (zh) 2013-07-31
CN102746296B (zh) 2015-10-28
KR101495269B1 (ko) 2015-02-26
EP2905283B1 (en) 2016-12-14
CA2679071C (en) 2016-06-07
RU2470022C2 (ru) 2012-12-20
BRPI0809977A8 (pt) 2017-12-26
CN101679415A (zh) 2010-03-24
EP2144910B1 (en) 2015-10-28

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