PL2945939T3 - Tiazolokarboksyamidy i związki pirydynokarboksyamidowe przydatne jako inhibitory kinaz pim - Google Patents

Tiazolokarboksyamidy i związki pirydynokarboksyamidowe przydatne jako inhibitory kinaz pim

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Publication number
PL2945939T3
PL2945939T3 PL14702389T PL14702389T PL2945939T3 PL 2945939 T3 PL2945939 T3 PL 2945939T3 PL 14702389 T PL14702389 T PL 14702389T PL 14702389 T PL14702389 T PL 14702389T PL 2945939 T3 PL2945939 T3 PL 2945939T3
Authority
PL
Poland
Prior art keywords
thiazolecarboxamides
kinase inhibitors
compounds useful
pim kinase
pyridinecarboxamide compounds
Prior art date
Application number
PL14702389T
Other languages
English (en)
Inventor
Chu-Biao Xue
Yun-Long Li
Hao Feng
Jun Pan
Anlai Wang
Ke Zhang
Wenqing Yao
Fenglei Zhang
Jincong Zhuo
Original Assignee
Incyte Holdings Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Holdings Corporation filed Critical Incyte Holdings Corporation
Publication of PL2945939T3 publication Critical patent/PL2945939T3/pl

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
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    • C07D495/04—Ortho-condensed systems

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PL14702389T 2013-01-15 2014-01-14 Tiazolokarboksyamidy i związki pirydynokarboksyamidowe przydatne jako inhibitory kinaz pim PL2945939T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361752897P 2013-01-15 2013-01-15
US201361790952P 2013-03-15 2013-03-15
US201361859118P 2013-07-26 2013-07-26
PCT/US2014/011486 WO2014113388A1 (en) 2013-01-15 2014-01-14 Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors
EP14702389.9A EP2945939B1 (en) 2013-01-15 2014-01-14 Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors

Publications (1)

Publication Number Publication Date
PL2945939T3 true PL2945939T3 (pl) 2020-08-24

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PL14702389T PL2945939T3 (pl) 2013-01-15 2014-01-14 Tiazolokarboksyamidy i związki pirydynokarboksyamidowe przydatne jako inhibitory kinaz pim

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US (7) US9200004B2 (pl)
EP (3) EP2945939B1 (pl)
JP (3) JP6554037B2 (pl)
KR (2) KR102403306B1 (pl)
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DK (1) DK2945939T3 (pl)
EA (1) EA035929B1 (pl)
EC (1) ECSP15035343A (pl)
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HR (1) HRP20200770T1 (pl)
HU (1) HUE050215T2 (pl)
IL (1) IL239886B (pl)
LT (1) LT2945939T (pl)
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NZ (2) NZ749911A (pl)
PE (2) PE20151448A1 (pl)
PH (2) PH12015501567B1 (pl)
PL (1) PL2945939T3 (pl)
PT (1) PT2945939T (pl)
RS (1) RS60244B1 (pl)
SG (3) SG10201705662WA (pl)
SI (1) SI2945939T1 (pl)
SM (1) SMT202000244T1 (pl)
TW (2) TWI662030B (pl)
UA (1) UA121098C2 (pl)
WO (1) WO2014113388A1 (pl)
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Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2734205T3 (en) 2011-07-21 2018-06-14 Tolero Pharmaceuticals Inc Heterocyclic Protein Kinase Inhibitors
TWI568722B (zh) 2012-06-15 2017-02-01 葛蘭馬克製藥公司 作爲ｍＰＧＥＳ－１抑制劑之三唑酮化合物
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