PL2970345T3 - Znakowane 18F środki do obrazowania PET ukierunkowane na PSMA - Google Patents

Znakowane 18F środki do obrazowania PET ukierunkowane na PSMA

Info

Publication number
PL2970345T3
PL2970345T3 PL14721640T PL14721640T PL2970345T3 PL 2970345 T3 PL2970345 T3 PL 2970345T3 PL 14721640 T PL14721640 T PL 14721640T PL 14721640 T PL14721640 T PL 14721640T PL 2970345 T3 PL2970345 T3 PL 2970345T3
Authority
PL
Poland
Prior art keywords
imaging agents
pet imaging
agents targeting
targeting psma
labeled pet
Prior art date
Application number
PL14721640T
Other languages
English (en)
Inventor
Clifford BERKMAN
Svetlana A. Stekhova
Original Assignee
Cancer Targeted Technology Llc
Washington State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Targeted Technology Llc, Washington State University filed Critical Cancer Targeted Technology Llc
Publication of PL2970345T3 publication Critical patent/PL2970345T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0489Phosphates or phosphonates, e.g. bone-seeking phosphonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0402Organic compounds carboxylic acid carriers, fatty acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/24Esteramides
    • C07F9/2404Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/24Esteramides
    • C07F9/2404Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2416Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of cycloaliphatic alcohols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/24Esteramides
    • C07F9/2454Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2458Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL14721640T 2013-03-15 2014-03-14 Znakowane 18F środki do obrazowania PET ukierunkowane na PSMA PL2970345T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361798108P 2013-03-15 2013-03-15
PCT/US2014/027820 WO2014143736A1 (en) 2013-03-15 2014-03-14 18f-labeled psma-targeted pet imaging agents
EP14721640.2A EP2970345B1 (en) 2013-03-15 2014-03-14 18f-labeled psma-targeted pet imaging agents

Publications (1)

Publication Number Publication Date
PL2970345T3 true PL2970345T3 (pl) 2019-12-31

Family

ID=50639969

Family Applications (2)

Application Number Title Priority Date Filing Date
PL14721640T PL2970345T3 (pl) 2013-03-15 2014-03-14 Znakowane 18F środki do obrazowania PET ukierunkowane na PSMA
PL19179758.8T PL3560937T3 (pl) 2013-03-15 2014-03-14 Znakowane 18F środki do obrazowania PET ukierunkowane na PSMA i metody diagnostyczne je wykorzystujące

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL19179758.8T PL3560937T3 (pl) 2013-03-15 2014-03-14 Znakowane 18F środki do obrazowania PET ukierunkowane na PSMA i metody diagnostyczne je wykorzystujące

Country Status (17)

Country Link
US (3) US11554183B2 (pl)
EP (3) EP3560937B1 (pl)
CN (2) CN108558939B (pl)
AU (2) AU2014228233B2 (pl)
CA (1) CA2903131C (pl)
DK (2) DK3560937T3 (pl)
ES (2) ES2743433T3 (pl)
FI (1) FI3560937T3 (pl)
HR (2) HRP20191482T1 (pl)
HU (2) HUE046194T2 (pl)
LT (2) LT2970345T (pl)
PL (2) PL2970345T3 (pl)
PT (2) PT3560937T (pl)
RS (1) RS64011B1 (pl)
SI (2) SI3560937T1 (pl)
SM (1) SMT202300035T1 (pl)
WO (1) WO2014143736A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017027870A1 (en) * 2015-08-13 2017-02-16 The Johns Hopkins University Triazole conjugated ureas, thioureas, carbamates, and "reversed" carbamates for psma-targeted imaging agents and uses thereof
AU2017311510B2 (en) 2016-08-10 2021-11-18 Cancer Targeted Technology Llc Chelated PSMA inhibitors
EP3600024B1 (en) 2017-03-22 2024-10-23 SafeOp Surgical, Inc. Medical system and method for detecting changes in electrophysiological evoked potentials
WO2018233798A1 (en) 2017-06-20 2018-12-27 ITM Isotopen Technologien München AG Novel psma-binding agents and uses thereof
CA3060143A1 (en) 2017-05-24 2018-11-29 Itm Isotopen Technologien Munchen Ag Novel psma-binding agents and uses thereof
WO2020108753A1 (en) 2018-11-28 2020-06-04 ITM Isotopen Technologien München AG Novel tumor antigen binding agents and uses thereof
WO2020224780A1 (en) 2019-05-08 2020-11-12 ITM Isotopen Technologien München AG Para-aminohippuric acid (pah) as a renal protective substance
WO2021046233A1 (en) 2019-09-03 2021-03-11 Cancer Targeted Technology Llc Chelate-containing psma inhibitors
WO2022096103A1 (en) 2020-11-05 2022-05-12 ITM Isotopen Technologien München AG Combination of para-aminohippuric acid (pah) and radiolabeled complexes for treating cancer
WO2022111800A1 (en) 2020-11-25 2022-06-02 Itm Solucin Gmbh Stable formulations for radionuclide complexes
IL307381A (en) 2021-04-02 2023-11-01 Advanced Accelerator Applications Diagnostic methods of prostate cancer
WO2025038752A1 (en) 2023-08-14 2025-02-20 Cancer Targeted Technology Llc Psma binding ligand-linker conjugates and methods for use thereof
WO2026027442A1 (en) 2024-08-01 2026-02-05 Novartis Ag Synthesis of a precursor of radiopharmaceutical products

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2645809C (en) * 2006-03-14 2015-05-26 Cancer Targeted Technology Llc Peptidomimetic inhibitors of psma, compounds comprising them, and methods of use
MX2009002492A (es) * 2006-09-08 2009-08-28 Bayer Schering Pharma Ag Agentes que comprenden compuestos marcados con 18f y metodos relacionados.
PT2318366T (pt) * 2008-08-01 2017-08-02 Univ Johns Hopkins Agentes de ligação a psma e suas utilizações
US9328129B2 (en) * 2010-11-12 2016-05-03 Washington State University Peptidomimetic inhibitors of PSMA
WO2012174136A1 (en) * 2011-06-15 2012-12-20 Cancer Targeted Technology Llc Chelated psma inhibitors
CN102757296B (zh) * 2012-04-10 2014-11-19 中国科学院上海应用物理研究所 一种对化合物进行[18f]标记的方法
WO2013173583A1 (en) 2012-05-16 2013-11-21 Cancer Targeted Technology, Llc Psma inhibitors
WO2013173630A1 (en) 2012-05-16 2013-11-21 Cancer Targeted Technology, Llc Formulation of radiopharmaceuticals containing multiple acidic groups

Also Published As

Publication number Publication date
US11554183B2 (en) 2023-01-17
CA2903131C (en) 2021-11-23
AU2019203610B2 (en) 2021-02-04
HUE061402T2 (hu) 2023-06-28
AU2014228233B2 (en) 2019-02-28
ES2743433T3 (es) 2020-02-19
HRP20230109T1 (hr) 2023-04-28
SI2970345T1 (sl) 2019-11-29
EP2970345A1 (en) 2016-01-20
HUE046194T2 (hu) 2020-02-28
HRP20191482T1 (hr) 2019-11-15
DK2970345T3 (da) 2019-08-26
EP3560937B1 (en) 2022-12-28
US20230144322A1 (en) 2023-05-11
CN105308056B (zh) 2018-03-20
AU2014228233A1 (en) 2015-09-17
CA2903131A1 (en) 2014-09-18
LT2970345T (lt) 2019-09-25
CN108558939B (zh) 2021-08-24
CN105308056A (zh) 2016-02-03
CN108558939A (zh) 2018-09-21
PT3560937T (pt) 2023-02-13
US20250375542A1 (en) 2025-12-11
AU2019203610A1 (en) 2019-06-13
EP3560937A1 (en) 2019-10-30
EP4180438A1 (en) 2023-05-17
WO2014143736A1 (en) 2014-09-18
FI3560937T3 (fi) 2023-02-28
ES2937955T3 (es) 2023-04-03
RS64011B1 (sr) 2023-03-31
US20160030605A1 (en) 2016-02-04
PT2970345T (pt) 2019-09-06
SMT202300035T1 (it) 2023-05-12
EP2970345B1 (en) 2019-06-19
DK3560937T3 (da) 2023-02-13
SI3560937T1 (sl) 2023-04-28
PL3560937T3 (pl) 2023-03-27
LT3560937T (lt) 2023-03-27

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