DK3560937T3 - Fremgangsmåder til fremstilling af 18f-mærkede psma-målrettede billeddannelsesmidler og diagnostiske fremgangsmåder dermed - Google Patents
Fremgangsmåder til fremstilling af 18f-mærkede psma-målrettede billeddannelsesmidler og diagnostiske fremgangsmåder dermed Download PDFInfo
- Publication number
- DK3560937T3 DK3560937T3 DK19179758.8T DK19179758T DK3560937T3 DK 3560937 T3 DK3560937 T3 DK 3560937T3 DK 19179758 T DK19179758 T DK 19179758T DK 3560937 T3 DK3560937 T3 DK 3560937T3
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- making
- imaging agents
- labeled psma
- targeting imaging
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2416—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of cycloaliphatic alcohols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2458—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361798108P | 2013-03-15 | 2013-03-15 | |
| EP14721640.2A EP2970345B1 (en) | 2013-03-15 | 2014-03-14 | 18f-labeled psma-targeted pet imaging agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3560937T3 true DK3560937T3 (da) | 2023-02-13 |
Family
ID=50639969
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19179758.8T DK3560937T3 (da) | 2013-03-15 | 2014-03-14 | Fremgangsmåder til fremstilling af 18f-mærkede psma-målrettede billeddannelsesmidler og diagnostiske fremgangsmåder dermed |
| DK14721640.2T DK2970345T3 (da) | 2013-03-15 | 2014-03-14 | 18f-mærkede psma-targeterede pet-kontrastmidler |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14721640.2T DK2970345T3 (da) | 2013-03-15 | 2014-03-14 | 18f-mærkede psma-targeterede pet-kontrastmidler |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US11554183B2 (da) |
| EP (3) | EP2970345B1 (da) |
| CN (2) | CN105308056B (da) |
| AU (2) | AU2014228233B2 (da) |
| CA (1) | CA2903131C (da) |
| DK (2) | DK3560937T3 (da) |
| ES (2) | ES2743433T3 (da) |
| FI (1) | FI3560937T3 (da) |
| HR (2) | HRP20191482T1 (da) |
| HU (2) | HUE061402T2 (da) |
| LT (2) | LT2970345T (da) |
| PL (2) | PL2970345T3 (da) |
| PT (2) | PT2970345T (da) |
| RS (1) | RS64011B1 (da) |
| SI (2) | SI2970345T1 (da) |
| SM (1) | SMT202300035T1 (da) |
| WO (1) | WO2014143736A1 (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11078166B2 (en) | 2015-08-13 | 2021-08-03 | The Johns Hopkins University | Triazole conjugated ureas, thioureas, carbamates, and reversed carbamates for PSMA-targeted imaging agents and uses thereof |
| MX392700B (es) * | 2016-08-10 | 2025-03-11 | Cancer Targeted Tech Llc | Inhibidores de antígeno de la membrana específico para la próstata (psma) quelados. |
| EP3600024B1 (en) | 2017-03-22 | 2024-10-23 | SafeOp Surgical, Inc. | Medical system and method for detecting changes in electrophysiological evoked potentials |
| WO2018233798A1 (en) | 2017-06-20 | 2018-12-27 | ITM Isotopen Technologien München AG | NOVEL PSMA BINDING AGENTS AND USE THEREOF |
| CA3060143A1 (en) | 2017-05-24 | 2018-11-29 | Itm Isotopen Technologien Munchen Ag | Novel psma-binding agents and uses thereof |
| WO2020108753A1 (en) | 2018-11-28 | 2020-06-04 | ITM Isotopen Technologien München AG | Novel tumor antigen binding agents and uses thereof |
| WO2020224780A1 (en) | 2019-05-08 | 2020-11-12 | ITM Isotopen Technologien München AG | Para-aminohippuric acid (pah) as a renal protective substance |
| WO2021046233A1 (en) | 2019-09-03 | 2021-03-11 | Cancer Targeted Technology Llc | Chelate-containing psma inhibitors |
| WO2022096103A1 (en) | 2020-11-05 | 2022-05-12 | ITM Isotopen Technologien München AG | Combination of para-aminohippuric acid (pah) and radiolabeled complexes for treating cancer |
| WO2022111800A1 (en) | 2020-11-25 | 2022-06-02 | Itm Solucin Gmbh | Stable formulations for radionuclide complexes |
| CA3215723A1 (en) | 2021-04-02 | 2022-10-06 | Advanced Accelerator Applications | Diagnostic methods of prostate cancer |
| EP4761763A1 (en) | 2023-08-14 | 2026-06-24 | Cancer Targeted Technology LLC | Psma binding ligand-linker conjugates and methods for use thereof |
| WO2026027442A1 (en) | 2024-08-01 | 2026-02-05 | Novartis Ag | Synthesis of a precursor of radiopharmaceutical products |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL1999136T3 (pl) | 2006-03-14 | 2013-03-29 | Cancer Targeted Tech Llc | Peptydomimetyczne inhibitory PSMA, związki je zawierające i sposoby ich zastosowania |
| BRPI0716554A2 (pt) * | 2006-09-08 | 2013-09-24 | Bayer Schering Pharma Ag | compostos de mÉtodos para agentes rotulados de 18f |
| ES2634894T3 (es) * | 2008-08-01 | 2017-09-29 | The Johns Hopkins University | Agentes de unión a PSMA y usos de los mismos |
| WO2012064914A2 (en) * | 2010-11-12 | 2012-05-18 | Washington State University Research Foundation | Peptidomimetic inhibitors of psma |
| PL2721039T3 (pl) * | 2011-06-15 | 2018-06-29 | Cancer Targeted Technology Llc | Chelatowane inhibitory PSMA |
| CN102757296B (zh) * | 2012-04-10 | 2014-11-19 | 中国科学院上海应用物理研究所 | 一种对化合物进行[18f]标记的方法 |
| WO2013173630A1 (en) * | 2012-05-16 | 2013-11-21 | Cancer Targeted Technology, Llc | Formulation of radiopharmaceuticals containing multiple acidic groups |
| WO2013173583A1 (en) * | 2012-05-16 | 2013-11-21 | Cancer Targeted Technology, Llc | Psma inhibitors |
-
2014
- 2014-03-14 SM SM20230035T patent/SMT202300035T1/it unknown
- 2014-03-14 PL PL14721640T patent/PL2970345T3/pl unknown
- 2014-03-14 CN CN201480021159.XA patent/CN105308056B/zh active Active
- 2014-03-14 US US14/774,371 patent/US11554183B2/en active Active
- 2014-03-14 ES ES14721640T patent/ES2743433T3/es active Active
- 2014-03-14 SI SI201431305T patent/SI2970345T1/sl unknown
- 2014-03-14 AU AU2014228233A patent/AU2014228233B2/en active Active
- 2014-03-14 CN CN201810256877.5A patent/CN108558939B/zh active Active
- 2014-03-14 PT PT14721640T patent/PT2970345T/pt unknown
- 2014-03-14 ES ES19179758T patent/ES2937955T3/es active Active
- 2014-03-14 EP EP14721640.2A patent/EP2970345B1/en active Active
- 2014-03-14 FI FIEP19179758.8T patent/FI3560937T3/fi active
- 2014-03-14 HR HRP20191482 patent/HRP20191482T1/hr unknown
- 2014-03-14 HU HUE19179758A patent/HUE061402T2/hu unknown
- 2014-03-14 HR HRP20230109TT patent/HRP20230109T1/hr unknown
- 2014-03-14 EP EP19179758.8A patent/EP3560937B1/en active Active
- 2014-03-14 PL PL19179758.8T patent/PL3560937T3/pl unknown
- 2014-03-14 RS RS20230089A patent/RS64011B1/sr unknown
- 2014-03-14 DK DK19179758.8T patent/DK3560937T3/da active
- 2014-03-14 CA CA2903131A patent/CA2903131C/en active Active
- 2014-03-14 LT LTEP14721640.2T patent/LT2970345T/lt unknown
- 2014-03-14 LT LTEP19179758.8T patent/LT3560937T/lt unknown
- 2014-03-14 DK DK14721640.2T patent/DK2970345T3/da active
- 2014-03-14 EP EP22215508.7A patent/EP4180438A1/en not_active Withdrawn
- 2014-03-14 WO PCT/US2014/027820 patent/WO2014143736A1/en not_active Ceased
- 2014-03-14 HU HUE14721640A patent/HUE046194T2/hu unknown
- 2014-03-14 SI SI201432018T patent/SI3560937T1/sl unknown
- 2014-03-14 PT PT191797588T patent/PT3560937T/pt unknown
-
2019
- 2019-05-22 AU AU2019203610A patent/AU2019203610B2/en active Active
-
2023
- 2023-01-04 US US18/149,981 patent/US20230144322A1/en not_active Abandoned
-
2025
- 2025-08-27 US US19/311,913 patent/US20250375542A1/en active Pending
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