PL2970413T3 - Zmodyfikowana sulfamidaza i jej wytwarzanie - Google Patents

Zmodyfikowana sulfamidaza i jej wytwarzanie

Info

Publication number
PL2970413T3
PL2970413T3 PL15713502T PL15713502T PL2970413T3 PL 2970413 T3 PL2970413 T3 PL 2970413T3 PL 15713502 T PL15713502 T PL 15713502T PL 15713502 T PL15713502 T PL 15713502T PL 2970413 T3 PL2970413 T3 PL 2970413T3
Authority
PL
Poland
Prior art keywords
production
modified sulfamidase
sulfamidase
modified
Prior art date
Application number
PL15713502T
Other languages
English (en)
Inventor
Charlotta BERGHARD
Erik Nordling
Stefan SVENSSON GELIUS
Agneta Tjernberg
Original Assignee
Swedish Orphan Biovitrum Ab (Publ)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Swedish Orphan Biovitrum Ab (Publ) filed Critical Swedish Orphan Biovitrum Ab (Publ)
Publication of PL2970413T3 publication Critical patent/PL2970413T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y310/00—Hydrolases acting on sulfur-nitrogen bonds (3.10)
    • C12Y310/01—Hydrolases acting on sulfur-nitrogen bonds (3.10) acting on sulfur-nitrogen bonds (3.10.1)
    • C12Y310/01001—N-Sulfoglucosamine sulfohydrolase (3.10.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
PL15713502T 2014-04-01 2015-04-01 Zmodyfikowana sulfamidaza i jej wytwarzanie PL2970413T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14162996 2014-04-01
PCT/EP2015/057256 WO2015150490A1 (en) 2014-04-01 2015-04-01 Modified sulfamidase and production thereof
EP15713502.1A EP2970413B1 (en) 2014-04-01 2015-04-01 Modified sulfamidase and production thereof

Publications (1)

Publication Number Publication Date
PL2970413T3 true PL2970413T3 (pl) 2018-12-31

Family

ID=50389999

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15713502T PL2970413T3 (pl) 2014-04-01 2015-04-01 Zmodyfikowana sulfamidaza i jej wytwarzanie

Country Status (31)

Country Link
US (2) US9982243B2 (pl)
EP (2) EP2970413B1 (pl)
JP (1) JP6594896B2 (pl)
KR (1) KR20160138282A (pl)
CN (1) CN106414727A (pl)
AU (1) AU2015239126B2 (pl)
BR (1) BR112016022333A2 (pl)
CA (1) CA2943140A1 (pl)
CL (1) CL2016002469A1 (pl)
CY (1) CY1120697T1 (pl)
DK (1) DK2970413T3 (pl)
ES (1) ES2687262T3 (pl)
HK (1) HK1231510A1 (pl)
HR (1) HRP20181507T1 (pl)
HU (1) HUE039691T2 (pl)
IL (1) IL247978A0 (pl)
LT (1) LT2970413T (pl)
MA (1) MA38816B1 (pl)
MX (1) MX368947B (pl)
PH (1) PH12016501812A1 (pl)
PL (1) PL2970413T3 (pl)
PT (1) PT2970413T (pl)
RS (1) RS57842B1 (pl)
RU (1) RU2708026C2 (pl)
SA (1) SA516371859B1 (pl)
SG (1) SG11201608025QA (pl)
SI (1) SI2970413T1 (pl)
SM (1) SMT201800511T1 (pl)
UA (1) UA120432C2 (pl)
WO (1) WO2015150490A1 (pl)
ZA (1) ZA201606492B (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SMT201800511T1 (it) 2014-04-01 2018-11-09 Swedish Orphan Biovitrum Ab Publ Sulfamidasi modificata e sua produzione
JP2018535654A (ja) * 2015-10-01 2018-12-06 スウェディッシュ オーファン バイオビトラム アクティエボラーグ （ペーウーベーエル） 修飾リソソームタンパク質とその製造
BR112020005271A2 (pt) 2017-10-02 2020-09-15 Denali Therapeutics Inc. proteína, polipeptídeo, polinucleotídeo, vetor, célula hospedeira, método para produção de um polipeptídeo, métodos de tratamento de um distúrbio, de diminuição do acúmulo, de monitoramento, de transporte de um agente e de tratamento de um lsd e composição farmacêutica
WO2019145500A1 (en) 2018-01-26 2019-08-01 Swedish Orphan Biovitrum Ab (Publ) Method of treatment
US11708569B2 (en) 2018-08-29 2023-07-25 University Of Copenhagen Modified recombinant lysosomal alpha-galactosidase A and aspartylglucoaminidase having low mannose-6-phosphate and high sialic acid
EP3741867A1 (en) 2019-05-24 2020-11-25 Swedish Orphan Biovitrum AB (Publ) Sulfatase activity assay
CR20230178A (es) 2020-10-14 2023-07-26 Denali Therapeutics Inc Proteínas de fusión que comprenden enzimas sulfoglucosamina sulfohidrolasa y métodos de estas

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863782A (en) 1995-04-19 1999-01-26 Women's And Children's Hospital Synthetic mammalian sulphamidase and genetic sequences encoding same
EP0909277B2 (en) 1996-06-07 2008-12-24 Poniard Pharmaceuticals, Inc. Humanized antibodies that bind to the same antigen as bound by antibody nr-lu-13, and their use in pretargeting methods
US7560424B2 (en) 2001-04-30 2009-07-14 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US8008252B2 (en) 2001-10-10 2011-08-30 Novo Nordisk A/S Factor VII: remodeling and glycoconjugation of Factor VII
WO2003032913A2 (en) 2001-10-16 2003-04-24 Symbiontics Inc. Methods and compositions for targeting proteins across the blood brain barrier
MXPA05000063A (es) 2002-07-01 2005-04-08 Kenneth S Warren Inst Inc Citocinas recombinantes protectoras de tejido y acidos nucleicos que las codifican para la proteccion, restauracion y mejora de celulas, tejidos y organos respondedores.
WO2008109677A2 (en) * 2007-03-06 2008-09-12 Saint Louis University Modified enzyme and treatment method
PL3219795T3 (pl) * 2008-01-18 2024-09-16 Biomarin Pharmaceutical Inc. Wytwarzanie aktywnych wysoce fosforylowanych ludzkich enzymów sulfatazy lizosomalnej i ich zastosowania
EP2394667A1 (en) * 2010-06-10 2011-12-14 Laboratorios Del Dr. Esteve, S.A. Vectors and sequences for the treatment of diseases
US9206401B2 (en) 2010-12-22 2015-12-08 Fondazione Telethon Therapeutic strategies to treat CNS pathology in mucopolysaccharidoses
ES2664844T3 (es) * 2011-06-20 2018-04-23 Mount Sinai School Of Medicine Tratamiento dirigido contra TNF para las mucopolisacaridosis y otros trastornos lisosómicos
WO2014194427A1 (en) 2013-06-06 2014-12-11 Angiochem Inc. Targeted iduronate-2-sulfatase fusion proteins
US20140377246A1 (en) 2013-06-19 2014-12-25 Carol Ann Foundation and International Morquio Organization Enzyme replacement therapy for treating mps vii related bone lesions using a chemically modified enzyme
SMT201800511T1 (it) 2014-04-01 2018-11-09 Swedish Orphan Biovitrum Ab Publ Sulfamidasi modificata e sua produzione

Also Published As

Publication number Publication date
MA38816A (fr) 2016-01-20
SI2970413T1 (sl) 2018-10-30
IL247978A0 (en) 2016-11-30
EP2970413A1 (en) 2016-01-20
PT2970413T (pt) 2018-10-23
EP2970413B1 (en) 2018-07-04
US20180320152A1 (en) 2018-11-08
CL2016002469A1 (es) 2017-12-15
LT2970413T (lt) 2018-10-10
MX2016012910A (es) 2017-07-14
WO2015150490A1 (en) 2015-10-08
MA38816B1 (fr) 2018-10-31
JP2017514462A (ja) 2017-06-08
CN106414727A (zh) 2017-02-15
CA2943140A1 (en) 2015-10-08
RU2016140844A3 (pl) 2018-10-11
HK1231510A1 (zh) 2017-12-22
PH12016501812A1 (en) 2017-07-24
HRP20181507T1 (hr) 2018-11-16
AU2015239126B2 (en) 2019-05-02
EP3401325A1 (en) 2018-11-14
KR20160138282A (ko) 2016-12-02
SA516371859B1 (ar) 2019-01-17
SG11201608025QA (en) 2016-10-28
MX368947B (es) 2019-10-22
RS57842B1 (sr) 2018-12-31
SMT201800511T1 (it) 2018-11-09
ZA201606492B (en) 2019-02-27
RU2708026C2 (ru) 2019-12-03
US20160230155A1 (en) 2016-08-11
JP6594896B2 (ja) 2019-10-23
DK2970413T3 (en) 2018-10-15
ES2687262T3 (es) 2018-10-24
AU2015239126A1 (en) 2016-10-27
HUE039691T2 (hu) 2019-01-28
CY1120697T1 (el) 2019-12-11
RU2016140844A (ru) 2018-05-10
BR112016022333A2 (pt) 2017-08-15
US9982243B2 (en) 2018-05-29
UA120432C2 (uk) 2019-12-10

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