PT2970413T - Sulfamidase modificada e sua produção - Google Patents

Sulfamidase modificada e sua produção

Info

Publication number
PT2970413T
PT2970413T PT15713502T PT15713502T PT2970413T PT 2970413 T PT2970413 T PT 2970413T PT 15713502 T PT15713502 T PT 15713502T PT 15713502 T PT15713502 T PT 15713502T PT 2970413 T PT2970413 T PT 2970413T
Authority
PT
Portugal
Prior art keywords
production
modified sulfamidase
sulfamidase
modified
Prior art date
Application number
PT15713502T
Other languages
English (en)
Inventor
Nordling Erik
Berghard Charlotta
Svensson Gelius Stefan
TJERNBERG Agneta
Original Assignee
Swedish Orphan Biovitrum Ab Publ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Swedish Orphan Biovitrum Ab Publ filed Critical Swedish Orphan Biovitrum Ab Publ
Publication of PT2970413T publication Critical patent/PT2970413T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y310/00—Hydrolases acting on sulfur-nitrogen bonds (3.10)
    • C12Y310/01—Hydrolases acting on sulfur-nitrogen bonds (3.10) acting on sulfur-nitrogen bonds (3.10.1)
    • C12Y310/01001—N-Sulfoglucosamine sulfohydrolase (3.10.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT15713502T 2014-04-01 2015-04-01 Sulfamidase modificada e sua produção PT2970413T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14162996 2014-04-01

Publications (1)

Publication Number Publication Date
PT2970413T true PT2970413T (pt) 2018-10-23

Family

ID=50389999

Family Applications (1)

Application Number Title Priority Date Filing Date
PT15713502T PT2970413T (pt) 2014-04-01 2015-04-01 Sulfamidase modificada e sua produção

Country Status (31)

Country Link
US (2) US9982243B2 (pt)
EP (2) EP3401325A1 (pt)
JP (1) JP6594896B2 (pt)
KR (1) KR20160138282A (pt)
CN (1) CN106414727A (pt)
AU (1) AU2015239126B2 (pt)
BR (1) BR112016022333A2 (pt)
CA (1) CA2943140A1 (pt)
CL (1) CL2016002469A1 (pt)
CY (1) CY1120697T1 (pt)
DK (1) DK2970413T3 (pt)
ES (1) ES2687262T3 (pt)
HK (1) HK1231510A1 (pt)
HR (1) HRP20181507T1 (pt)
HU (1) HUE039691T2 (pt)
IL (1) IL247978A0 (pt)
LT (1) LT2970413T (pt)
MA (1) MA38816B1 (pt)
MX (1) MX368947B (pt)
PH (1) PH12016501812A1 (pt)
PL (1) PL2970413T3 (pt)
PT (1) PT2970413T (pt)
RS (1) RS57842B1 (pt)
RU (1) RU2708026C2 (pt)
SA (1) SA516371859B1 (pt)
SG (1) SG11201608025QA (pt)
SI (1) SI2970413T1 (pt)
SM (1) SMT201800511T1 (pt)
UA (1) UA120432C2 (pt)
WO (1) WO2015150490A1 (pt)
ZA (1) ZA201606492B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE039691T2 (hu) 2014-04-01 2019-01-28 Swedish Orphan Biovitrum Ab Publ Módosított szulfamidáz és elõállítása
CA3000289A1 (en) * 2015-10-01 2017-04-06 Swedish Orphan Biovitrum Ab (Publ) Modified lysosomal protein and production thereof
AU2018345303B2 (en) 2017-10-02 2025-09-18 Denali Therapeutics Inc. Fusion proteins comprising enzyme replacement therapy enzymes
WO2019145500A1 (en) 2018-01-26 2019-08-01 Swedish Orphan Biovitrum Ab (Publ) Method of treatment
WO2020047282A1 (en) 2018-08-29 2020-03-05 University Of Copenhagen Lysosomal enzymes modified by cell based glycoengineering
EP3741867A1 (en) 2019-05-24 2020-11-25 Swedish Orphan Biovitrum AB (Publ) Sulfatase activity assay
PE20231931A1 (es) 2020-10-14 2023-12-01 Denali Therapeutics Inc Proteinas de fusion que comprenden enzimas sulfoglucosamina sulfohidrolasa y metodos de estas

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863782A (en) 1995-04-19 1999-01-26 Women's And Children's Hospital Synthetic mammalian sulphamidase and genetic sequences encoding same
WO1997046589A2 (en) 1996-06-07 1997-12-11 Neorx Corporation Humanized antibodies that bind to the same antigen as bound by antibody nr-lu-13, and their use in pretargeting methods
US7560424B2 (en) 2001-04-30 2009-07-14 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US8008252B2 (en) 2001-10-10 2011-08-30 Novo Nordisk A/S Factor VII: remodeling and glycoconjugation of Factor VII
WO2003032913A2 (en) 2001-10-16 2003-04-24 Symbiontics Inc. Methods and compositions for targeting proteins across the blood brain barrier
CA2491567A1 (en) 2002-07-01 2004-01-08 The Kenneth S. Warren Institute, Inc. Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
WO2008109677A2 (en) * 2007-03-06 2008-09-12 Saint Louis University Modified enzyme and treatment method
CN105274072A (zh) * 2008-01-18 2016-01-27 生物马林药物股份有限公司 制备活性高度磷酸化人溶酶体硫酸酯酶及其应用
EP2394667A1 (en) * 2010-06-10 2011-12-14 Laboratorios Del Dr. Esteve, S.A. Vectors and sequences for the treatment of diseases
AU2010366066B2 (en) * 2010-12-22 2016-01-14 Fondazione Telethon Therapeutic strategies to treat CNS pathology in mucopolysaccharidoses
WO2012177778A1 (en) * 2011-06-20 2012-12-27 Mount Sinai School Of Medicine Anti-tnf- therapy for the mucopolysaccharidoses and other lysosomal disorders
WO2014194427A1 (en) 2013-06-06 2014-12-11 Angiochem Inc. Targeted iduronate-2-sulfatase fusion proteins
US20140377246A1 (en) 2013-06-19 2014-12-25 Carol Ann Foundation and International Morquio Organization Enzyme replacement therapy for treating mps vii related bone lesions using a chemically modified enzyme
HUE039691T2 (hu) 2014-04-01 2019-01-28 Swedish Orphan Biovitrum Ab Publ Módosított szulfamidáz és elõállítása

Also Published As

Publication number Publication date
JP2017514462A (ja) 2017-06-08
ES2687262T3 (es) 2018-10-24
US20180320152A1 (en) 2018-11-08
EP2970413A1 (en) 2016-01-20
MA38816B1 (fr) 2018-10-31
HUE039691T2 (hu) 2019-01-28
HK1231510A1 (zh) 2017-12-22
CN106414727A (zh) 2017-02-15
BR112016022333A2 (pt) 2017-08-15
CA2943140A1 (en) 2015-10-08
MX2016012910A (es) 2017-07-14
RU2708026C2 (ru) 2019-12-03
CY1120697T1 (el) 2019-12-11
JP6594896B2 (ja) 2019-10-23
EP2970413B1 (en) 2018-07-04
RU2016140844A3 (pt) 2018-10-11
IL247978A0 (en) 2016-11-30
AU2015239126B2 (en) 2019-05-02
SG11201608025QA (en) 2016-10-28
MX368947B (es) 2019-10-22
MA38816A (fr) 2016-01-20
SI2970413T1 (sl) 2018-10-30
PL2970413T3 (pl) 2018-12-31
US20160230155A1 (en) 2016-08-11
WO2015150490A1 (en) 2015-10-08
CL2016002469A1 (es) 2017-12-15
SMT201800511T1 (it) 2018-11-09
HRP20181507T1 (hr) 2018-11-16
DK2970413T3 (en) 2018-10-15
LT2970413T (lt) 2018-10-10
RS57842B1 (sr) 2018-12-31
AU2015239126A1 (en) 2016-10-27
ZA201606492B (en) 2019-02-27
RU2016140844A (ru) 2018-05-10
US9982243B2 (en) 2018-05-29
KR20160138282A (ko) 2016-12-02
PH12016501812A1 (en) 2017-07-24
EP3401325A1 (en) 2018-11-14
SA516371859B1 (ar) 2019-01-17
UA120432C2 (uk) 2019-12-10

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