PT2970413T - Sulfamidase modificada e sua produção - Google Patents

Sulfamidase modificada e sua produção

Info

Publication number
PT2970413T
PT2970413T PT15713502T PT15713502T PT2970413T PT 2970413 T PT2970413 T PT 2970413T PT 15713502 T PT15713502 T PT 15713502T PT 15713502 T PT15713502 T PT 15713502T PT 2970413 T PT2970413 T PT 2970413T
Authority
PT
Portugal
Prior art keywords
production
modified sulfamidase
sulfamidase
modified
Prior art date
Application number
PT15713502T
Other languages
English (en)
Inventor
Nordling Erik
Berghard Charlotta
Svensson Gelius Stefan
TJERNBERG Agneta
Original Assignee
Swedish Orphan Biovitrum Ab Publ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Swedish Orphan Biovitrum Ab Publ filed Critical Swedish Orphan Biovitrum Ab Publ
Publication of PT2970413T publication Critical patent/PT2970413T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y310/00—Hydrolases acting on sulfur-nitrogen bonds (3.10)
    • C12Y310/01—Hydrolases acting on sulfur-nitrogen bonds (3.10) acting on sulfur-nitrogen bonds (3.10.1)
    • C12Y310/01001—N-Sulfoglucosamine sulfohydrolase (3.10.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT15713502T 2014-04-01 2015-04-01 Sulfamidase modificada e sua produção PT2970413T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14162996 2014-04-01

Publications (1)

Publication Number Publication Date
PT2970413T true PT2970413T (pt) 2018-10-23

Family

ID=50389999

Family Applications (1)

Application Number Title Priority Date Filing Date
PT15713502T PT2970413T (pt) 2014-04-01 2015-04-01 Sulfamidase modificada e sua produção

Country Status (31)

Country Link
US (2) US9982243B2 (pt)
EP (2) EP2970413B1 (pt)
JP (1) JP6594896B2 (pt)
KR (1) KR20160138282A (pt)
CN (1) CN106414727A (pt)
AU (1) AU2015239126B2 (pt)
BR (1) BR112016022333A2 (pt)
CA (1) CA2943140A1 (pt)
CL (1) CL2016002469A1 (pt)
CY (1) CY1120697T1 (pt)
DK (1) DK2970413T3 (pt)
ES (1) ES2687262T3 (pt)
HK (1) HK1231510A1 (pt)
HR (1) HRP20181507T1 (pt)
HU (1) HUE039691T2 (pt)
IL (1) IL247978A0 (pt)
LT (1) LT2970413T (pt)
MA (1) MA38816B1 (pt)
MX (1) MX368947B (pt)
PH (1) PH12016501812A1 (pt)
PL (1) PL2970413T3 (pt)
PT (1) PT2970413T (pt)
RS (1) RS57842B1 (pt)
RU (1) RU2708026C2 (pt)
SA (1) SA516371859B1 (pt)
SG (1) SG11201608025QA (pt)
SI (1) SI2970413T1 (pt)
SM (1) SMT201800511T1 (pt)
UA (1) UA120432C2 (pt)
WO (1) WO2015150490A1 (pt)
ZA (1) ZA201606492B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20181507T1 (hr) 2014-04-01 2018-11-16 Swedish Orphan Biovitrum Ab (Publ) Modificirana sulfamidaza i njena proizvodnja
BR112018006278A2 (pt) * 2015-10-01 2018-10-16 Swedish Orphan Biovitrum Ab Publ proteína lisossômica modificada e produção da mesma
MX2020002918A (es) 2017-10-02 2020-07-22 Denali Therapeutics Inc Proteinas de fusion que comprenden enzimas de terapia de reemplazo de enzimas.
WO2019145500A1 (en) 2018-01-26 2019-08-01 Swedish Orphan Biovitrum Ab (Publ) Method of treatment
WO2020047282A1 (en) 2018-08-29 2020-03-05 University Of Copenhagen Lysosomal enzymes modified by cell based glycoengineering
EP3741867A1 (en) 2019-05-24 2020-11-25 Swedish Orphan Biovitrum AB (Publ) Sulfatase activity assay
AU2021362209B2 (en) 2020-10-14 2026-02-12 Denali Therapeutics Inc. Fusion proteins comprising sulfoglucosamine sulfohydrolase enzymes and methods thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863782A (en) 1995-04-19 1999-01-26 Women's And Children's Hospital Synthetic mammalian sulphamidase and genetic sequences encoding same
JP4503706B2 (ja) 1996-06-07 2010-07-14 ポニアード ファーマシューティカルズ，インコーポレイティド グリコシル化が改質されたヒト化抗体
US7560424B2 (en) 2001-04-30 2009-07-14 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US8008252B2 (en) 2001-10-10 2011-08-30 Novo Nordisk A/S Factor VII: remodeling and glycoconjugation of Factor VII
IL161352A0 (en) 2001-10-16 2004-09-27 Symbiontics Inc Methods and compositions for targeting underglycosylated proteins across the blood brain barrier
US20040122216A1 (en) 2002-07-01 2004-06-24 Jacob Nielsen Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
CA2680189A1 (en) * 2007-03-06 2008-09-12 Saint Louis University Modified enzyme and treatment method
EP2245145B1 (en) * 2008-01-18 2016-12-14 BioMarin Pharmaceutical Inc. Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
EP2394667A1 (en) * 2010-06-10 2011-12-14 Laboratorios Del Dr. Esteve, S.A. Vectors and sequences for the treatment of diseases
AU2010366066B2 (en) 2010-12-22 2016-01-14 Fondazione Telethon Therapeutic strategies to treat CNS pathology in mucopolysaccharidoses
WO2012177778A1 (en) * 2011-06-20 2012-12-27 Mount Sinai School Of Medicine Anti-tnf- therapy for the mucopolysaccharidoses and other lysosomal disorders
WO2014194427A1 (en) 2013-06-06 2014-12-11 Angiochem Inc. Targeted iduronate-2-sulfatase fusion proteins
US20140377246A1 (en) 2013-06-19 2014-12-25 Carol Ann Foundation and International Morquio Organization Enzyme replacement therapy for treating mps vii related bone lesions using a chemically modified enzyme
HRP20181507T1 (hr) 2014-04-01 2018-11-16 Swedish Orphan Biovitrum Ab (Publ) Modificirana sulfamidaza i njena proizvodnja

Also Published As

Publication number Publication date
IL247978A0 (en) 2016-11-30
RU2016140844A3 (pt) 2018-10-11
JP6594896B2 (ja) 2019-10-23
RS57842B1 (sr) 2018-12-31
CY1120697T1 (el) 2019-12-11
US20160230155A1 (en) 2016-08-11
MX2016012910A (es) 2017-07-14
CL2016002469A1 (es) 2017-12-15
EP2970413B1 (en) 2018-07-04
HRP20181507T1 (hr) 2018-11-16
AU2015239126A1 (en) 2016-10-27
EP3401325A1 (en) 2018-11-14
LT2970413T (lt) 2018-10-10
SG11201608025QA (en) 2016-10-28
PH12016501812A1 (en) 2017-07-24
JP2017514462A (ja) 2017-06-08
KR20160138282A (ko) 2016-12-02
UA120432C2 (uk) 2019-12-10
RU2016140844A (ru) 2018-05-10
MX368947B (es) 2019-10-22
AU2015239126B2 (en) 2019-05-02
RU2708026C2 (ru) 2019-12-03
SA516371859B1 (ar) 2019-01-17
SMT201800511T1 (it) 2018-11-09
ES2687262T3 (es) 2018-10-24
PL2970413T3 (pl) 2018-12-31
HK1231510A1 (zh) 2017-12-22
BR112016022333A2 (pt) 2017-08-15
CN106414727A (zh) 2017-02-15
EP2970413A1 (en) 2016-01-20
DK2970413T3 (en) 2018-10-15
MA38816B1 (fr) 2018-10-31
US9982243B2 (en) 2018-05-29
CA2943140A1 (en) 2015-10-08
MA38816A (fr) 2016-01-20
SI2970413T1 (sl) 2018-10-30
HUE039691T2 (hu) 2019-01-28
US20180320152A1 (en) 2018-11-08
WO2015150490A1 (en) 2015-10-08
ZA201606492B (en) 2019-02-27

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