PL3030519T3 - Trójpierścieniowe związki benzoksaborolu i ich zastosowania - Google Patents

Trójpierścieniowe związki benzoksaborolu i ich zastosowania

Info

Publication number: PL3030519T3
Authority: PL; Poland
Prior art keywords: circular; benzoxaborol compounds; benzoxaborol; compounds; circular benzoxaborol
Prior art date: 2013-08-09

Application number

PL14834292T

Other languages

English (en)

Inventor

M.R.K. ALLEY (Dickon)

Vincent S. Hernandez

Jacob J. Plattner

Xianfeng Li

David Barros-Aguirre

Ilaria Giordano

Original Assignee

Glaxosmithkline Intellectual Property (No. 2) Limited

Anacor Pharmaceuticals, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-08-09

Filing date

2014-08-08

Publication date

2022-05-23

2014-08-08 Application filed by Glaxosmithkline Intellectual Property (No. 2) Limited, Anacor Pharmaceuticals, Inc. filed Critical Glaxosmithkline Intellectual Property (No. 2) Limited

2022-05-23 Publication of PL3030519T3 publication Critical patent/PL3030519T3/pl

Links

GDMJXXLVTYSBBE-UHFFFAOYSA-N 1,2-benzoxaborole Chemical class C1=CC=C2OB=CC2=C1 GDMJXXLVTYSBBE-UHFFFAOYSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Neurology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

PL14834292T 2013-08-09 2014-08-08 Trójpierścieniowe związki benzoksaborolu i ich zastosowania PL3030519T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201361864496P	2013-08-09	2013-08-09
US201361918976P	2013-12-20	2013-12-20
EP14834292.6A EP3030519B1 (en)	2013-08-09	2014-08-08	Tricyclic benzoxaborole compounds and uses thereof
PCT/US2014/050370 WO2015021396A2 (en)	2013-08-09	2014-08-08	Tricyclic benzoxaborole compounds and uses thereof

Publications (1)

Publication Number	Publication Date
PL3030519T3 true PL3030519T3 (pl)	2022-05-23

Family

ID=52462052

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL14834292T PL3030519T3 (pl)	2013-08-09	2014-08-08	Trójpierścieniowe związki benzoksaborolu i ich zastosowania

Country Status (35)

Country	Link
US (5)	US20160251380A1 (pl)
EP (2)	EP4029870A1 (pl)
JP (2)	JP6499175B2 (pl)
KR (1)	KR102093783B1 (pl)
CN (2)	CN110003253B (pl)
AP (1)	AP2016009046A0 (pl)
AU (2)	AU2014305792C1 (pl)
BR (1)	BR112016002651B1 (pl)
CA (1)	CA2919888C (pl)
CL (1)	CL2016000313A1 (pl)
CR (1)	CR20160064A (pl)
CY (1)	CY1125030T1 (pl)
DK (1)	DK3030519T3 (pl)
DO (1)	DOP2016000045A (pl)
EA (1)	EA032844B1 (pl)
ES (1)	ES2905413T3 (pl)
HR (1)	HRP20220384T1 (pl)
HU (1)	HUE057365T2 (pl)
IL (1)	IL243874B (pl)
LT (1)	LT3030519T (pl)
MX (1)	MX375556B (pl)
MY (1)	MY175823A (pl)
NZ (1)	NZ716350A (pl)
PE (1)	PE20160752A1 (pl)
PH (1)	PH12016500234B1 (pl)
PL (1)	PL3030519T3 (pl)
PT (1)	PT3030519T (pl)
RS (1)	RS62887B1 (pl)
SA (1)	SA516370551B1 (pl)
SG (2)	SG10201914073PA (pl)
SI (1)	SI3030519T1 (pl)
SM (1)	SMT202200113T1 (pl)
UA (1)	UA116908C2 (pl)
WO (1)	WO2015021396A2 (pl)
ZA (1)	ZA201600792B (pl)

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AR094961A1 (es) *	2013-03-15	2015-09-09	Lilly Co Eli	1-hidroxi-benzooxaboroles como agentes antiparasitarios
KR101636431B1 (ko)	2013-07-30	2016-07-05	동아에스티 주식회사	트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도
EP4029870A1 (en)	2013-08-09	2022-07-20	GlaxoSmithKline Intellectual Property (No.2) Limited	Tricyclic benzoxaborole compounds and uses thereof
WO2016001834A1 (en)	2014-07-01	2016-01-07	Daiichi Sankyo Company, Limited	Tricyclic benzoxaboroles as antibacterial agents
MA41494B1 (fr)	2015-02-12	2020-10-28	Glaxosmithkline Ip No 2 Ltd	Composés benzoxaborole substitués en position 4 et utilisations associées
KR102243775B1 (ko)	2016-05-12	2021-04-22	아나코르 파마슈티칼스 인코포레이티드	옥사보롤 에스터 및 이의 용도
CN109387594B (zh) *	2017-08-08	2021-01-19	武汉武药科技有限公司	一种分离和分析贝达喹啉光学异构体的方法
PL3737685T3 (pl) *	2018-01-09	2023-10-02	Halcyon Labs Private Limited	Sposób wytwarzania kryzaborolu i jego związków pośrednich
EP4164645A4 (en) *	2020-06-15	2024-07-10	The Global Alliance for TB Drug Development, Inc.	COMBINED ANTIBACTERIAL COMPOSITION AND ANTIBACTERIAL THERAPY METHOD
CN111606850B (zh) *	2020-07-07	2023-07-25	安徽贝克生物制药有限公司	贝达喹啉及其中间体的制备方法
US11793808B2 (en)	2021-02-22	2023-10-24	Mannkind Corp.	Compositions of clofazimine, combinations comprising them, processes for their preparation, uses and methods comprising them
CA3239097A1 (en)	2022-06-23	2023-12-28	Shanghai Micurx Pharmaceutical Co., Ltd.	Prodrugs of boron compounds and their use in treating bacterial infections
CN119233823A (zh) *	2022-06-23	2024-12-31	上海盟科药业股份有限公司	硼化合物治疗非结核分枝杆菌感染的方法和用途及用于治疗相同疾病的药物组合物
EP4688794A1 (en)	2023-04-05	2026-02-11	GlaxoSmithKline Intellectual Property (No. 2) Limited	Synthesis of 3-(aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3)-ol
CN117379430A (zh) *	2023-10-11	2024-01-12	深圳市第三人民医院(深圳市肝病研究所)	一种地拉韦啶的用途

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EP0947498B1 (en)	1996-12-02	2004-09-15	Chisso Corporation	Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for preparing the same
EP1567464B1 (en)	2002-12-02	2007-04-18	Solvias AG	Catalytic hydrogeneration of carbon-heteroatom double bonds
SI3424932T1 (sl) *	2005-02-16	2021-08-31	Anacor Pharmaceuticals, Inc.	Boronoftalidi za terapevtsko uporabo
US7767657B2 (en) *	2005-02-16	2010-08-03	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules
WO2006096131A1 (en)	2005-03-08	2006-09-14	Agency For Science, Technology And Research	Chiral bisoxazoline catalysts
CN101505603A (zh) *	2005-12-30	2009-08-12	安纳考尔医药公司	含硼的小分子
KR100848491B1 (ko)	2007-01-16	2008-07-28	영진약품공업주식회사	베타아미노기를 갖는 2-싸이아졸리딘 유도체, 이의약학적으로 허용 가능한 염 및 이의 제조 방법
JO3396B1 (ar) *	2007-06-20	2019-10-20	Anacor Pharmaceuticals Inc	جزيئات صغيرة تحتوي على البورون
CN102256494A (zh)	2008-12-17	2011-11-23	阿纳科制药公司	(s)-3-氨甲基-7-(3-羟基-丙氧基)-3h-苯并[c][1,2]氧杂硼杂环戊-1-醇的多晶型物
EP2555625B1 (en) *	2010-04-07	2018-11-14	GlaxoSmithKline LLC	Process for preparing benzoxaboroles
PT3251678T (pt) *	2010-09-07	2021-11-22	Anacor Pharmaceuticals Inc	Derivados de benzoxaborol para tratamento de infeções bacterianas
US8530452B2 (en)	2011-12-22	2013-09-10	Micurx Pharmaceuticals, Inc.	Tricyclic boron compounds for antimicrobial therapy
KR101636431B1 (ko)	2013-07-30	2016-07-05	동아에스티 주식회사	트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도
EP4029870A1 (en) *	2013-08-09	2022-07-20	GlaxoSmithKline Intellectual Property (No.2) Limited	Tricyclic benzoxaborole compounds and uses thereof
MA41494B1 (fr) *	2015-02-12	2020-10-28	Glaxosmithkline Ip No 2 Ltd	Composés benzoxaborole substitués en position 4 et utilisations associées

2014
- 2014-08-08 EP EP21214787.0A patent/EP4029870A1/en not_active Withdrawn
- 2014-08-08 UA UAA201600796A patent/UA116908C2/uk unknown
- 2014-08-08 EP EP14834292.6A patent/EP3030519B1/en active Active
- 2014-08-08 LT LTEPPCT/US2014/050370T patent/LT3030519T/lt unknown
- 2014-08-08 HU HUE14834292A patent/HUE057365T2/hu unknown
- 2014-08-08 PT PT148342926T patent/PT3030519T/pt unknown
- 2014-08-08 CA CA2919888A patent/CA2919888C/en active Active
- 2014-08-08 PL PL14834292T patent/PL3030519T3/pl unknown
- 2014-08-08 CN CN201811396796.1A patent/CN110003253B/zh active Active
- 2014-08-08 SM SM20220113T patent/SMT202200113T1/it unknown
- 2014-08-08 CN CN201480049562.3A patent/CN105492388B/zh active Active
- 2014-08-08 MX MX2016001732A patent/MX375556B/es active IP Right Grant
- 2014-08-08 BR BR112016002651-9A patent/BR112016002651B1/pt active IP Right Grant
- 2014-08-08 RS RS20220108A patent/RS62887B1/sr unknown
- 2014-08-08 SG SG10201914073PA patent/SG10201914073PA/en unknown
- 2014-08-08 US US14/387,384 patent/US20160251380A1/en not_active Abandoned
- 2014-08-08 SI SI201431939T patent/SI3030519T1/sl unknown
- 2014-08-08 MY MYPI2016700458A patent/MY175823A/en unknown
- 2014-08-08 ES ES14834292T patent/ES2905413T3/es active Active
- 2014-08-08 NZ NZ716350A patent/NZ716350A/en unknown
- 2014-08-08 KR KR1020167006314A patent/KR102093783B1/ko active Active
- 2014-08-08 JP JP2016533471A patent/JP6499175B2/ja active Active
- 2014-08-08 AP AP2016009046A patent/AP2016009046A0/en unknown
- 2014-08-08 HR HRP20220384TT patent/HRP20220384T1/hr unknown
- 2014-08-08 PE PE2016000234A patent/PE20160752A1/es unknown
- 2014-08-08 AU AU2014305792A patent/AU2014305792C1/en active Active
- 2014-08-08 DK DK14834292.6T patent/DK3030519T3/da active
- 2014-08-08 WO PCT/US2014/050370 patent/WO2015021396A2/en not_active Ceased
- 2014-08-08 EA EA201690135A patent/EA032844B1/ru unknown
- 2014-08-08 SG SG11201600787PA patent/SG11201600787PA/en unknown
2016
- 2016-01-28 IL IL243874A patent/IL243874B/en active IP Right Grant
- 2016-02-03 PH PH12016500234A patent/PH12016500234B1/en unknown
- 2016-02-04 ZA ZA2016/00792A patent/ZA201600792B/en unknown
- 2016-02-07 SA SA516370551A patent/SA516370551B1/ar unknown
- 2016-02-08 CL CL2016000313A patent/CL2016000313A1/es unknown
- 2016-02-09 CR CR20160064A patent/CR20160064A/es unknown
- 2016-02-09 DO DO2016000045A patent/DOP2016000045A/es unknown
2017
- 2017-08-03 AU AU2017210567A patent/AU2017210567B2/en active Active
- 2017-10-24 US US15/792,251 patent/US10308668B2/en active Active
2019
- 2019-03-14 JP JP2019046582A patent/JP6764970B2/ja active Active
- 2019-04-16 US US16/385,547 patent/US10526352B2/en active Active
- 2019-11-26 US US16/695,253 patent/US10858376B2/en active Active
2020
- 2020-11-04 US US17/089,058 patent/US20210053999A1/en not_active Abandoned
2022
- 2022-03-01 CY CY20221100169T patent/CY1125030T1/el unknown

Also Published As

Publication number	Publication date
AU2014305792C1 (en)	2018-07-05
HUE057365T2 (hu)	2022-05-28
DK3030519T3 (da)	2022-01-31
CN110003253A (zh)	2019-07-12
PE20160752A1 (es)	2016-08-17
MY175823A (en)	2020-07-10
SG10201914073PA (en)	2020-03-30
DOP2016000045A (es)	2016-04-29
MX2016001732A (es)	2016-05-18
EP3030519A2 (en)	2016-06-15
ES2905413T3 (es)	2022-04-08
US20200095266A1 (en)	2020-03-26
CY1125030T1 (el)	2023-03-24
AP2016009046A0 (en)	2016-02-29
CR20160064A (es)	2016-06-01
US20180044355A1 (en)	2018-02-15
EP3030519B1 (en)	2022-01-05
WO2015021396A9 (en)	2016-02-11
PH12016500234A1 (en)	2016-05-16
CA2919888C (en)	2022-10-18
US20160251380A1 (en)	2016-09-01
AU2014305792A1 (en)	2016-03-10
EA201690135A1 (ru)	2016-07-29
RS62887B1 (sr)	2022-03-31
CN105492388A (zh)	2016-04-13
SA516370551B1 (ar)	2017-10-31
CL2016000313A1 (es)	2016-09-23
KR20160038901A (ko)	2016-04-07
LT3030519T (lt)	2022-04-11
CN110003253B (zh)	2022-03-18
JP6499175B2 (ja)	2019-04-10
HK1219939A1 (zh)	2017-04-21
PH12016500234B1 (en)	2019-01-30
EP4029870A1 (en)	2022-07-20
AU2017210567B2 (en)	2019-08-01
SMT202200113T1 (it)	2022-05-12
EA032844B1 (ru)	2019-07-31
IL243874A0 (en)	2016-04-21
UA116908C2 (uk)	2018-05-25
KR102093783B1 (ko)	2020-03-26
SG11201600787PA (en)	2016-03-30
EP3030519A4 (en)	2017-03-08
HRP20220384T1 (hr)	2022-07-22
SI3030519T1 (sl)	2022-04-29
JP6764970B2 (ja)	2020-10-07
BR112016002651B1 (pt)	2022-11-29
CA2919888A1 (en)	2015-02-12
PT3030519T (pt)	2022-01-27
BR112016002651A2 (pt)	2017-08-01
NZ716350A (en)	2022-12-23
IL243874B (en)	2018-11-29
WO2015021396A2 (en)	2015-02-12
JP2019123727A (ja)	2019-07-25
US20210053999A1 (en)	2021-02-25
AU2017210567A1 (en)	2017-08-24
US10858376B2 (en)	2020-12-08
MX375556B (es)	2025-03-06
US20190241586A1 (en)	2019-08-08
CN105492388B (zh)	2018-12-21
ZA201600792B (en)	2022-05-25
WO2015021396A3 (en)	2015-10-29
JP2016527321A (ja)	2016-09-08
AU2014305792B2 (en)	2017-05-04
US10308668B2 (en)	2019-06-04
US10526352B2 (en)	2020-01-07

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EP2943489A4 (en)	2016-06-08	DEUTERATED MOMELOTINIB
DE102013106534B8 (de)	2015-06-18	Chromatographiepipettenspitze
EP2991647A4 (en)	2016-10-12	DEUTERED AMLEXANOX
EP2970310A4 (en)	2016-09-07	5-BROMO-indirubins
EP2853297A4 (en)	2016-02-24	kendama
DK3071227T3 (da)	2021-01-18	Fiskevaccine
PL3055307T3 (pl)	2020-07-27	Podstawione berbiny i ich synteza
EP3047192A4 (en)	2016-11-09	LOCKABLE LOCATED CONNECTOR
DE112014001252A5 (de)	2016-01-21	Aufbissschiene
DK3086679T3 (da)	2020-10-26	Sportssko
DK2981168T3 (da)	2020-04-06	Laminitiskile
FI10138U1 (fi)	2013-06-28	Kelkkateltta
ES1078715Y (es)	2013-12-02	Mosquitera
DE112014005422A5 (de)	2016-09-01	Friktionsfalschdrallaggregat
FI10093U1 (fi)	2013-05-16	Jalusta