PL3097189T3 - Chimeryczne białka podobne do alkalicznej fosfatazy - Google Patents

Chimeryczne białka podobne do alkalicznej fosfatazy

Info

Publication number
PL3097189T3
PL3097189T3 PL15703642T PL15703642T PL3097189T3 PL 3097189 T3 PL3097189 T3 PL 3097189T3 PL 15703642 T PL15703642 T PL 15703642T PL 15703642 T PL15703642 T PL 15703642T PL 3097189 T3 PL3097189 T3 PL 3097189T3
Authority
PL
Poland
Prior art keywords
alkaline phosphatase
chimeric proteins
proteins similar
similar
chimeric
Prior art date
Application number
PL15703642T
Other languages
English (en)
Inventor
Willem Raaben
Luigi Johannes Cornelius Jonk
Andrea Van Elsas
Erik Jan VAN DEN BERG
José Luis MILLÁN
Original Assignee
Am-Pharma B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Am-Pharma B.V. filed Critical Am-Pharma B.V.
Publication of PL3097189T3 publication Critical patent/PL3097189T3/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03001—Alkaline phosphatase (3.1.3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Plant Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
PL15703642T 2014-01-24 2015-01-26 Chimeryczne białka podobne do alkalicznej fosfatazy PL3097189T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP14152526 2014-01-24
EP14188158 2014-10-08
EP15703642.7A EP3097189B1 (en) 2014-01-24 2015-01-26 Chimeric alkaline phosphatase-like proteins
PCT/NL2015/050048 WO2015112017A1 (en) 2014-01-24 2015-01-26 Chimeric alkaline phosphatase-like proteins

Publications (1)

Publication Number Publication Date
PL3097189T3 true PL3097189T3 (pl) 2018-11-30

Family

ID=52464544

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15703642T PL3097189T3 (pl) 2014-01-24 2015-01-26 Chimeryczne białka podobne do alkalicznej fosfatazy

Country Status (22)

Country Link
US (4) US9926544B2 (pl)
EP (2) EP3425048A1 (pl)
JP (3) JP6940949B2 (pl)
KR (1) KR102166110B1 (pl)
CN (2) CN106164262B (pl)
AU (1) AU2015209783B2 (pl)
BR (1) BR112016017041B1 (pl)
CA (1) CA2937328C (pl)
DK (1) DK3097189T3 (pl)
ES (1) ES2684639T3 (pl)
HU (1) HUE039784T2 (pl)
IL (1) IL246898B (pl)
MX (1) MX369041B (pl)
PE (1) PE20161442A1 (pl)
PH (1) PH12016501441B1 (pl)
PL (1) PL3097189T3 (pl)
RU (1) RU2683635C2 (pl)
SA (1) SA516371532B1 (pl)
SG (1) SG11201606060WA (pl)
SI (1) SI3097189T1 (pl)
WO (1) WO2015112017A1 (pl)
ZA (1) ZA201605028B (pl)

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Also Published As

Publication number Publication date
BR112016017041B1 (pt) 2023-09-26
US20190024062A1 (en) 2019-01-24
JP6940949B2 (ja) 2021-09-29
JP2017505128A (ja) 2017-02-16
RU2016131879A (ru) 2018-03-01
KR102166110B1 (ko) 2020-10-16
US10822597B2 (en) 2020-11-03
SI3097189T1 (sl) 2018-10-30
PH12016501441A1 (en) 2016-08-22
US20170009216A1 (en) 2017-01-12
JP2020058375A (ja) 2020-04-16
WO2015112017A1 (en) 2015-07-30
SG11201606060WA (en) 2016-08-30
PE20161442A1 (es) 2017-01-12
ES2684639T3 (es) 2018-10-03
AU2015209783B2 (en) 2020-10-01
JP7408734B2 (ja) 2024-01-05
PH12016501441B1 (en) 2023-02-22
SA516371532B1 (ar) 2019-02-11
US20210163905A1 (en) 2021-06-03
NZ722253A (en) 2021-11-26
US9926544B2 (en) 2018-03-27
IL246898B (en) 2019-09-26
CN111778228A (zh) 2020-10-16
CA2937328C (en) 2022-09-27
HUE039784T2 (hu) 2019-02-28
CN106164262A (zh) 2016-11-23
EP3097189A1 (en) 2016-11-30
US20240174994A1 (en) 2024-05-30
EP3097189B1 (en) 2018-07-11
BR112016017041A2 (pt) 2017-10-03
US12534713B2 (en) 2026-01-27
ZA201605028B (en) 2020-02-26
RU2683635C2 (ru) 2019-03-29
DK3097189T3 (en) 2018-09-03
IL246898A0 (en) 2016-09-29
MX369041B (es) 2019-10-25
KR20160117487A (ko) 2016-10-10
CN106164262B (zh) 2020-08-07
CA2937328A1 (en) 2015-07-30
JP2022160503A (ja) 2022-10-19
US11746340B2 (en) 2023-09-05
RU2016131879A3 (pl) 2018-08-16
EP3425048A1 (en) 2019-01-09
AU2015209783A1 (en) 2016-08-04
MX2016009625A (es) 2017-05-01

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