PL3192874T3 - Oczyszczanie wirusa - Google Patents
Oczyszczanie wirusaInfo
- Publication number
- PL3192874T3 PL3192874T3 PL16002644T PL16002644T PL3192874T3 PL 3192874 T3 PL3192874 T3 PL 3192874T3 PL 16002644 T PL16002644 T PL 16002644T PL 16002644 T PL16002644 T PL 16002644T PL 3192874 T3 PL3192874 T3 PL 3192874T3
- Authority
- PL
- Poland
- Prior art keywords
- virus purification
- virus
- purification
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0091—Purification or manufacturing processes for gene therapy compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15051—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Manufacturing & Machinery (AREA)
- Plant Pathology (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7368508P | 2008-06-18 | 2008-06-18 | |
| PCT/GB2009/001527 WO2009153563A1 (en) | 2008-06-18 | 2009-06-18 | Virus purification |
| EP09766124.3A EP2307551B1 (en) | 2008-06-18 | 2009-06-18 | Purification of retroviral vectors |
| EP16002644.9A EP3192874B1 (en) | 2008-06-18 | 2009-06-18 | Virus purification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3192874T3 true PL3192874T3 (pl) | 2020-06-29 |
Family
ID=40940324
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09766124T PL2307551T3 (pl) | 2008-06-18 | 2009-06-18 | Oczyszczanie wektorów retrowirusowych |
| PL16002644T PL3192874T3 (pl) | 2008-06-18 | 2009-06-18 | Oczyszczanie wirusa |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09766124T PL2307551T3 (pl) | 2008-06-18 | 2009-06-18 | Oczyszczanie wektorów retrowirusowych |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9169491B2 (pl) |
| EP (2) | EP3192874B1 (pl) |
| JP (2) | JP5615271B2 (pl) |
| CN (2) | CN102124115B (pl) |
| DK (2) | DK3192874T3 (pl) |
| ES (2) | ES2762864T3 (pl) |
| PL (2) | PL2307551T3 (pl) |
| WO (1) | WO2009153563A1 (pl) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2529020T3 (en) * | 2010-01-28 | 2018-08-06 | Childrens Hospital Philadelphia | SCALABLE PREPARATION PLATF FOR CLEANING VIRAL VECTORS AND CLEANED VIRAL VECTORS FOR USE IN GENTHERAPY |
| CN102946907A (zh) | 2010-05-28 | 2013-02-27 | 牛津生物医学（英国）有限公司 | 慢病毒载体向脑的递送 |
| GB201118636D0 (en) | 2011-10-28 | 2011-12-07 | Oxford Biomedica Ltd | Nucleotide sequence |
| PT2782997T (pt) | 2011-11-24 | 2018-04-09 | Genethon | Sistema de produção de vetor lentiviral escalável compatível com aplicações farmacêuticas industriais |
| US20140349403A1 (en) | 2011-12-12 | 2014-11-27 | The Children's Hospital Of Philadelphia | Large commercial scale lentiviral vector production system and vectors produced thereby |
| WO2013106398A1 (en) * | 2012-01-09 | 2013-07-18 | Sanofi Pasteur Biologics, Llc | Purification of herpes virus |
| WO2013177172A2 (en) | 2012-05-21 | 2013-11-28 | Sanofi Pasteur Limited | Herpesvirus compositions and related methods |
| SI3889173T1 (sl) | 2013-02-15 | 2023-11-30 | Bioverativ Therapeutics Inc. | Optimiran gen dejavnika VIII |
| RU2709678C2 (ru) * | 2013-03-15 | 2019-12-19 | Дзе Чилдрен'З Хоспитал Оф Филадельфия | Масштабный производственный способ получения рекомбинантных лентивирусных векторов в системе культивирования клеток в бессывороточной суспензии |
| FR3010720B1 (fr) | 2013-09-16 | 2017-08-11 | Genethon | Procede de production de virus enveloppes |
| FR3014901B1 (fr) | 2013-12-17 | 2017-06-09 | Genethon | Procede de purification de virus ou vecteurs viraux enveloppes |
| GB201322798D0 (en) | 2013-12-20 | 2014-02-05 | Oxford Biomedica Ltd | Production system |
| EP3160478A4 (en) | 2014-06-30 | 2018-05-16 | Bioverativ Therapeutics Inc. | Optimized factor ix gene |
| CN104371982A (zh) * | 2014-10-21 | 2015-02-25 | 武汉维诺赛生物技术有限公司 | 一种慢病毒的纯化方法 |
| ES2904301T3 (es) | 2014-11-03 | 2022-04-04 | Academisch Ziekenhuis Leiden H O D N Leids Univ Medisch Centrum | Receptores de células T dirigidos contra Bob1 y usos de los mismos |
| EP3054007A1 (en) | 2015-02-09 | 2016-08-10 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Recombinant adeno-associated virus particle purification comprising an immuno-affinity purification step |
| JP2018510627A (ja) | 2015-03-10 | 2018-04-19 | レイデン ユニバーシティ メディカル センター | メラノーマ優先発現抗原に対して向けられたｔ細胞レセプターおよびその使用 |
| US10711282B2 (en) | 2015-11-23 | 2020-07-14 | Novartis Ag | Optimized lentiviral transfer vectors and uses thereof |
| WO2017136358A1 (en) | 2016-02-01 | 2017-08-10 | Bioverativ Therapeutics Inc. | Optimized factor viii genes |
| CN107043784A (zh) * | 2016-02-05 | 2017-08-15 | 上海吉凯基因化学技术有限公司 | 一种慢病毒载体的制备方法 |
| JP2019519250A (ja) | 2016-05-10 | 2019-07-11 | ユナイテッド ステイツ ガバメント アズ リプレゼンテッド バイ ザ デパートメント オブ ベテランズ アフェアーズＵｎｉｔｅｄ Ｓｔａｔｅｓ Ｇｏｖｅｒｎｍｅｎｔ Ａｓ Ｒｅｐｒｅｓｅｎｔｅｄ Ｂｙ Ｔｈｅ Ｄｅｐａｒｔｍｅｎｔ Ｏｆ Ｖｅｔｅｒａｎｓ Ａｆｆａｉｒｓ | Ｈｉｖ−１感染と複製に必須な遺伝子を切断するｃｒｉｓｐｒ／ｃａｓの構築物のレンチウィルスによる送達 |
| GB201614050D0 (en) * | 2016-08-17 | 2016-09-28 | Glaxosmithkline Ip Dev Ltd | Method for purifying viral vectors |
| MA50877A (fr) | 2017-11-21 | 2020-09-30 | Bayer Healthcare Llc | Matériaux et méthodes pour le traitement de la rétinite pigmentaire autosomique dominante |
| WO2019123429A1 (en) | 2017-12-21 | 2019-06-27 | Casebia Therapeutics Llp | Materials and methods for treatment of usher syndrome type 2a |
| WO2019123430A1 (en) | 2017-12-21 | 2019-06-27 | Casebia Therapeutics Llp | Materials and methods for treatment of usher syndrome type 2a and/or non-syndromic autosomal recessive retinitis pigmentosa (arrp) |
| EP3633040B1 (en) | 2017-12-22 | 2023-06-07 | Oxford BioMedica (UK) Limited | Retroviral vector |
| JP2021520232A (ja) * | 2018-04-05 | 2021-08-19 | オックスフォード ユニバーシティ イノベーション リミテッドＯｘｆｏｒｄ Ｕｎｉｖｅｒｓｉｔｙ Ｉｎｎｏｖａｔｉｏｎ Ｌｉｍｉｔｅｄ | 黄斑ジストロフィーを処置するための組成物及び方法 |
| US11529413B2 (en) | 2018-06-12 | 2022-12-20 | Kbio Holdings Limited | Virus and antigen purification and conjugation |
| US11690907B2 (en) | 2018-06-12 | 2023-07-04 | Kbio Holdings Limited | Vaccines formed by virus and antigen conjugation |
| US11696948B2 (en) | 2018-06-12 | 2023-07-11 | Kbio Holdings Limited | Vaccines formed by virus and antigen conjugation |
| IL279295B2 (en) | 2018-06-12 | 2026-03-01 | Kentucky Bioprocessing Inc | Purification and cross-linking of virus and antigen |
| JP2021533831A (ja) * | 2018-08-16 | 2021-12-09 | スペースクラフト セブン リミテッド ライアビリティ カンパニー | ウイルスベクターのための生成方法 |
| US20220175962A1 (en) | 2019-03-10 | 2022-06-09 | Sio Gene Therapies Inc. | Gene therapy compositions and methods for treating parkinson's disease |
| US20220243224A1 (en) * | 2019-04-15 | 2022-08-04 | Children's Hospital Medical Center | Viral vector manufacturing methods |
| US12037599B2 (en) | 2019-08-23 | 2024-07-16 | Lonza Walkersville, Inc. | Methods and constructs for production of lentiviral vector |
| JP7803014B2 (ja) | 2019-09-30 | 2026-01-21 | バイオベラティブ セラピューティクス インコーポレイテッド | レンチウイルスベクター製剤 |
| WO2021094752A1 (en) | 2019-11-12 | 2021-05-20 | Oxford Biomedica (Uk) Limited | Production system |
| JP2023513303A (ja) | 2020-02-13 | 2023-03-30 | オックスフォード バイオメディカ（ユーケー）リミテッド | レンチウイルスベクターの製造 |
| US20230118587A1 (en) | 2020-03-13 | 2023-04-20 | Oxford Biomedica (Uk) Limited | Lentiviral Vectors |
| CN116096430A (zh) | 2020-04-27 | 2023-05-09 | 衣阿华大学研究基金会 | 用于治疗囊性纤维化的组合物和方法 |
| GB202007199D0 (en) | 2020-05-15 | 2020-07-01 | Oxford Biomedica Ltd | Viral vector production |
| US12173307B2 (en) | 2020-06-24 | 2024-12-24 | Bioverativ Therapeutics Inc. | Methods for the purification of viral vectors |
| AU2021324776A1 (en) * | 2020-08-13 | 2023-04-13 | Tmunity Therapeutics Inc. | Methods for producing clinical-grade lentiviral vector |
| CN112226418B (zh) * | 2020-09-25 | 2022-07-08 | 阜外华中心血管病医院 | 重组腺相关病毒纯化方法 |
| CN116529382A (zh) * | 2020-10-02 | 2023-08-01 | 吉恩勒克斯公司 | 由贴壁细胞在生物反应器中产生病毒 |
| GB202017725D0 (en) | 2020-11-10 | 2020-12-23 | Oxford Biomedica Ltd | Method |
| CN112899242A (zh) * | 2021-02-03 | 2021-06-04 | 苏州博腾生物制药有限公司 | 慢病毒纯化工艺 |
| GB202114532D0 (en) | 2021-10-12 | 2021-11-24 | Oxford Biomedica Ltd | Lentiviral Vectors |
| GB202114529D0 (en) | 2021-10-12 | 2021-11-24 | Oxford Biomedica Ltd | Lentiviral vectors |
| GB202114528D0 (en) | 2021-10-12 | 2021-11-24 | Oxford Biomedica Ltd | Lentiviral vectors |
| GB202114534D0 (en) | 2021-10-12 | 2021-11-24 | Oxford Biomedica Ltd | Novel viral regulatory elements |
| GB202114530D0 (en) | 2021-10-12 | 2021-11-24 | Oxford Biomedica Ltd | Retroviral vectors |
| EP4424705A4 (en) | 2021-10-29 | 2026-02-18 | Agc Inc | Composition for adding cells |
| WO2023085382A1 (ja) | 2021-11-12 | 2023-05-19 | Ａｇｃ株式会社 | ウイルスの精製方法 |
| GB202117844D0 (en) | 2021-12-09 | 2022-01-26 | Oxford Biomedica Ltd | Purification method |
| GB202211935D0 (en) | 2022-08-16 | 2022-09-28 | Oxford Biomedica Ltd | envelope proteins |
| CN116240241A (zh) * | 2022-12-30 | 2023-06-09 | 上海本导基因技术有限公司 | 重组慢病毒载体的纯化制备方法 |
| CN121002189A (zh) * | 2023-02-01 | 2025-11-21 | 因特尔乌斯生物治疗公司 | 用于过滤或纯化病毒颗粒的方法 |
| WO2024259299A1 (en) | 2023-06-14 | 2024-12-19 | The Broad Institute, Inc. | Compositions and methods for identification of vhh antibodies that bind a target antigen |
| WO2025235738A1 (en) * | 2024-05-08 | 2025-11-13 | Interius Biotherapeutics, Inc. | Methods of detecting residual dna in viral preparations |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL78703A (en) | 1985-05-10 | 1993-02-21 | Benzon Alfred | Method of producing extracellular enzymes, the enzymes produced thereby and compositions containing them; a hybrid plasmid and a dna fragment comprising dna encoding the enzymes; a microorganism harbouring the plasmid; and a method for removing nucleic acids from biological materials |
| DE4006630A1 (de) | 1990-03-03 | 1991-09-12 | Behringwerke Ag | Humane monoklonale antikoerper gegen tollwutviren, ihre herstellung und verwendung |
| DE69131908T3 (de) | 1991-02-19 | 2008-04-03 | Oxford Biomedica (Uk) Ltd. | Viruspartikel mit veraendertem wirtspektrum |
| US5512421A (en) | 1991-02-19 | 1996-04-30 | The Regents Of The University Of California | Generation, concentration and efficient transfer of VSV-G pseudotyped retroviral vectors |
| EP0738319A4 (en) * | 1994-01-12 | 2000-03-29 | Genetic Therapy Inc | Purification of retroviral vectors |
| DE69515028T2 (de) | 1994-03-22 | 2000-06-29 | The Immune Response Corp., Carlsbad | Die hocheffiziente herstellung und isolierung von viruspartikeln |
| US5681746A (en) | 1994-12-30 | 1997-10-28 | Chiron Viagene, Inc. | Retroviral delivery of full length factor VIII |
| US5837520A (en) | 1995-03-07 | 1998-11-17 | Canji, Inc. | Method of purification of viral vectors |
| US5723315A (en) | 1996-08-23 | 1998-03-03 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| US6100071A (en) | 1996-05-07 | 2000-08-08 | Genentech, Inc. | Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production |
| DE69729007T2 (de) | 1996-08-07 | 2005-04-07 | Darwin Discovery Ltd., Slough | Hydroxamsäure- und carbonsäure-derivate mit mmp und tnf hemmender wirkung |
| US6126939A (en) | 1996-09-03 | 2000-10-03 | Yeda Research And Development Co. Ltd. | Anti-inflammatory dipeptide and pharmaceutical composition thereof |
| WO1999061639A2 (en) | 1998-05-22 | 1999-12-02 | Oxford Biomedica (Uk) Limited | Retroviral delivery system |
| PL332875A1 (en) | 1996-10-17 | 1999-10-25 | Oxford Biomedica Ltd | Retroviral vectors |
| ES2278399T3 (es) * | 1996-11-20 | 2007-08-01 | Introgen Therapeutics, Inc. | Metodo mejorado para la produccion y purificacion de vectores adenovirales. |
| US6261823B1 (en) | 1996-12-13 | 2001-07-17 | Schering Corporation | Methods for purifying viruses |
| GB9720465D0 (en) | 1997-09-25 | 1997-11-26 | Oxford Biomedica Ltd | Dual-virus vectors |
| GB9803351D0 (en) | 1998-02-17 | 1998-04-15 | Oxford Biomedica Ltd | Anti-viral vectors |
| GB9904905D0 (en) | 1999-03-03 | 1999-04-28 | Oxford Biomedica Ltd | Cells |
| GB0009760D0 (en) | 2000-04-19 | 2000-06-07 | Oxford Biomedica Ltd | Method |
| GB0024550D0 (pl) | 2000-10-06 | 2000-11-22 | Oxford Biomedica Ltd | |
| JP2005521417A (ja) * | 2002-03-29 | 2005-07-21 | メルク エンド カムパニー インコーポレーテッド | アデノウイルスの大規模産生方法及びアデノウイルス種子ストック |
| DE60335672D1 (de) | 2002-05-14 | 2011-02-17 | Merck Sharp & Dohme | Verfahren zur reinigung von adenovirus |
| JP4992032B2 (ja) | 2002-09-03 | 2012-08-08 | オックスフォード バイオメディカ（ユーケー）リミテッド | レトロウイルスベクター |
| ATE488252T1 (de) | 2003-05-05 | 2010-12-15 | Virxsys Corp | Erhöhte transduktion mit abc- transportersubstratenhemmern |
| SE0302509D0 (sv) | 2003-09-19 | 2003-09-19 | Amersham Biosciences Ab | Matrix for separation of polyethers and method of separation |
| WO2005039643A2 (en) * | 2003-10-20 | 2005-05-06 | Nsgene A/S | In vivo gene therapy of parkinson's disease |
| NZ548495A (en) * | 2004-02-23 | 2009-05-31 | Crucell Holland Bv | Virus purification methods |
| GB0526211D0 (en) | 2005-12-22 | 2006-02-01 | Oxford Biomedica Ltd | Viral vectors |
| GB0526210D0 (en) | 2005-12-22 | 2006-02-01 | Oxford Biomedica Ltd | Vectors |
| PL2007883T3 (pl) | 2006-04-20 | 2012-07-31 | Wyeth Llc | Sposób oczyszczania do izolacji oczyszczonego wirusa pęcherzykowatego zapalenia jamy ustnej z hodowli komórkowej |
| EP2091966A2 (en) * | 2006-12-01 | 2009-08-26 | Oxford BioMedica (UK) Limited | Promoter construct |
| CA2678774A1 (en) * | 2007-03-01 | 2008-09-04 | Advanced Vision Therapies, Inc. | Treatment of diseases characterized by inflammation |
| CA2705850C (en) * | 2007-11-13 | 2016-07-19 | Bio-Technology General (Israel) Ltd. | Dilute filtration sterilization process for viscoelastic biopolymers |
-
2009
- 2009-06-18 PL PL09766124T patent/PL2307551T3/pl unknown
- 2009-06-18 WO PCT/GB2009/001527 patent/WO2009153563A1/en not_active Ceased
- 2009-06-18 EP EP16002644.9A patent/EP3192874B1/en active Active
- 2009-06-18 JP JP2011514119A patent/JP5615271B2/ja active Active
- 2009-06-18 ES ES16002644T patent/ES2762864T3/es active Active
- 2009-06-18 PL PL16002644T patent/PL3192874T3/pl unknown
- 2009-06-18 EP EP09766124.3A patent/EP2307551B1/en active Active
- 2009-06-18 US US12/487,215 patent/US9169491B2/en active Active
- 2009-06-18 DK DK16002644.9T patent/DK3192874T3/da active
- 2009-06-18 DK DK09766124.3T patent/DK2307551T3/en active
- 2009-06-18 ES ES09766124.3T patent/ES2618851T3/es active Active
- 2009-06-18 CN CN200980132555.9A patent/CN102124115B/zh not_active Expired - Fee Related
- 2009-06-18 CN CN201410244813.5A patent/CN103993040B/zh not_active Expired - Fee Related
-
2014
- 2014-07-10 JP JP2014142447A patent/JP6002720B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN103993040B (zh) | 2018-02-13 |
| JP5615271B2 (ja) | 2014-10-29 |
| EP2307551B1 (en) | 2016-12-14 |
| CN102124115B (zh) | 2020-03-03 |
| JP6002720B2 (ja) | 2016-10-05 |
| PL2307551T3 (pl) | 2017-07-31 |
| JP2011524887A (ja) | 2011-09-08 |
| CN103993040A (zh) | 2014-08-20 |
| EP3192874A1 (en) | 2017-07-19 |
| US9169491B2 (en) | 2015-10-27 |
| EP3192874B1 (en) | 2019-10-16 |
| WO2009153563A1 (en) | 2009-12-23 |
| ES2762864T3 (es) | 2020-05-26 |
| EP2307551A1 (en) | 2011-04-13 |
| DK2307551T3 (en) | 2017-03-20 |
| JP2014237661A (ja) | 2014-12-18 |
| ES2618851T3 (es) | 2017-06-22 |
| US20090325284A1 (en) | 2009-12-31 |
| CN102124115A (zh) | 2011-07-13 |
| DK3192874T3 (da) | 2019-12-16 |
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