PL333187A1 - Method of detecting compounds which modulate the performance of protein of obesity (ob) - Google Patents

Method of detecting compounds which modulate the performance of protein of obesity (ob)

Info

Publication number
PL333187A1
PL333187A1 PL97333187A PL33318797A PL333187A1 PL 333187 A1 PL333187 A1 PL 333187A1 PL 97333187 A PL97333187 A PL 97333187A PL 33318797 A PL33318797 A PL 33318797A PL 333187 A1 PL333187 A1 PL 333187A1
Authority
PL
Poland
Prior art keywords
obesity
modulate
protein
performance
detecting compounds
Prior art date
Application number
PL97333187A
Other languages
English (en)
Inventor
Lee James Beeley
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9622868.9A external-priority patent/GB9622868D0/en
Priority claimed from GBGB9622869.7A external-priority patent/GB9622869D0/en
Priority claimed from GBGB9622850.7A external-priority patent/GB9622850D0/en
Priority claimed from GBGB9622870.5A external-priority patent/GB9622870D0/en
Priority claimed from GBGB9622867.1A external-priority patent/GB9622867D0/en
Priority claimed from GBGB9622866.3A external-priority patent/GB9622866D0/en
Priority claimed from GBGB9622847.3A external-priority patent/GB9622847D0/en
Priority claimed from GBGB9622865.5A external-priority patent/GB9622865D0/en
Priority claimed from GBGB9622849.9A external-priority patent/GB9622849D0/en
Priority claimed from GBGB9622851.5A external-priority patent/GB9622851D0/en
Priority claimed from GBGB9622848.1A external-priority patent/GB9622848D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of PL333187A1 publication Critical patent/PL333187A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/5759Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PL97333187A 1996-11-01 1997-10-30 Method of detecting compounds which modulate the performance of protein of obesity (ob) PL333187A1 (en)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
GBGB9622869.7A GB9622869D0 (en) 1996-11-01 1996-11-01 Novel method
GBGB9622850.7A GB9622850D0 (en) 1996-11-01 1996-11-01 Novel method
GBGB9622870.5A GB9622870D0 (en) 1996-11-01 1996-11-01 Novel method
GBGB9622867.1A GB9622867D0 (en) 1996-11-01 1996-11-01 Novel method
GBGB9622868.9A GB9622868D0 (en) 1996-11-01 1996-11-01 Novel method
GBGB9622866.3A GB9622866D0 (en) 1996-11-01 1996-11-01 Novel method
GBGB9622847.3A GB9622847D0 (en) 1996-11-01 1996-11-01 Novel method
GBGB9622865.5A GB9622865D0 (en) 1996-11-01 1996-11-01 Novel method
GBGB9622849.9A GB9622849D0 (en) 1996-11-01 1996-11-01 Novel method
GBGB9622851.5A GB9622851D0 (en) 1996-11-01 1996-11-01 Novel method
GBGB9622848.1A GB9622848D0 (en) 1996-11-01 1996-11-01 Novel method
PCT/GB1997/002988 WO1998020158A1 (en) 1996-11-01 1997-10-30 Method for the detection of compounds that modulate the effects of the obese (ob) protein

Publications (1)

Publication Number Publication Date
PL333187A1 true PL333187A1 (en) 1999-11-22

Family

ID=27581686

Family Applications (1)

Application Number Title Priority Date Filing Date
PL97333187A PL333187A1 (en) 1996-11-01 1997-10-30 Method of detecting compounds which modulate the performance of protein of obesity (ob)

Country Status (13)

Country Link
EP (1) EP0951564A1 (cs)
JP (1) JP2001503982A (cs)
KR (1) KR20000053007A (cs)
AR (1) AR010262A1 (cs)
AU (1) AU4789297A (cs)
CA (1) CA2270431A1 (cs)
CZ (1) CZ149999A3 (cs)
IL (1) IL129685A0 (cs)
NO (1) NO992107L (cs)
NZ (1) NZ335489A (cs)
PL (1) PL333187A1 (cs)
TR (1) TR199900963T2 (cs)
WO (1) WO1998020158A1 (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1293533B1 (it) * 1997-07-14 1999-03-01 Angeletti P Ist Richerche Bio Metodo per la selezione di molecole in grado di mimare, inibire o potenziare gli effetti della interazione tra leptina e cellule che
GB9814199D0 (en) * 1998-06-30 1998-08-26 Univ Buckingham Novel method
EP1101112B1 (en) 1998-07-28 2004-10-06 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Leptin-mediated gene-induction
GB9828087D0 (en) * 1998-12-18 1999-02-17 Smithkline Beecham Plc Novel method
EP1283878B1 (en) 2000-05-22 2005-07-27 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Receptor-based interaction trap
GB0019327D0 (en) * 2000-08-08 2000-09-27 Buchanan Baillie Hamilton Paul Slimming system
EP1812038A1 (en) 2004-11-18 2007-08-01 VIB vzw Fibronectin iii domain as leptin receptor antagonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2285995A (en) * 1994-04-14 1995-11-10 Ligand Pharmaceuticals Incorporated Dna spacer regulatory elements responsive to cytokines and methods for their use
US5643748A (en) * 1994-09-14 1997-07-01 Progenitor, Inc. HU-B1.219, a novel human hematopoietin receptor
AU5524896A (en) * 1995-03-20 1996-10-08 Institut Pasteur De Lille Modulators of ob gene and screening methods therefor
US5712094A (en) * 1995-03-27 1998-01-27 Ligand Pharmaceuticals, Inc. Methods for detecting modulators of cytokine action
PL323638A1 (en) * 1995-05-30 1998-04-14 Smithkline Beecham Plc Method of detecting obesity protein modulating compounds
EP0914611A4 (en) * 1996-04-22 2002-10-16 Merck & Co Inc TRANSACTIVATION OF LEPTIN

Also Published As

Publication number Publication date
TR199900963T2 (xx) 1999-08-23
EP0951564A1 (en) 1999-10-27
JP2001503982A (ja) 2001-03-27
KR20000053007A (ko) 2000-08-25
CZ149999A3 (cs) 1999-10-13
NO992107L (no) 1999-06-30
NO992107D0 (no) 1999-04-30
WO1998020158A1 (en) 1998-05-14
NZ335489A (en) 2001-01-26
AU4789297A (en) 1998-05-29
CA2270431A1 (en) 1998-05-14
AR010262A1 (es) 2000-06-07
IL129685A0 (en) 2000-02-29

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