TR199900963T2 - Obez (OB) proteininin etkilerine uyan bile�iklerin tespit edilmesi i�in metot. - Google Patents

Obez (OB) proteininin etkilerine uyan bile�iklerin tespit edilmesi i�in metot.

Info

Publication number: TR199900963T2
Authority: TR; Turkey
Prior art keywords: protein; compound; response element; stat; effect
Prior art date: 1996-11-01

Application number

TR1999/00963T

Other languages

English (en)

Turkish (tr)

Inventor

Lee James Beeley Dr.

Original Assignee

Smithkline Beecham P.L.C.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-11-01

Filing date

1997-10-30

Publication date

1999-08-23

1996-11-01 Priority claimed from GBGB9622868.9A external-priority patent/GB9622868D0/en

1996-11-01 Priority claimed from GBGB9622869.7A external-priority patent/GB9622869D0/en

1996-11-01 Priority claimed from GBGB9622850.7A external-priority patent/GB9622850D0/en

1996-11-01 Priority claimed from GBGB9622870.5A external-priority patent/GB9622870D0/en

1996-11-01 Priority claimed from GBGB9622867.1A external-priority patent/GB9622867D0/en

1996-11-01 Priority claimed from GBGB9622866.3A external-priority patent/GB9622866D0/en

1996-11-01 Priority claimed from GBGB9622847.3A external-priority patent/GB9622847D0/en

1996-11-01 Priority claimed from GBGB9622865.5A external-priority patent/GB9622865D0/en

1996-11-01 Priority claimed from GBGB9622849.9A external-priority patent/GB9622849D0/en

1996-11-01 Priority claimed from GBGB9622851.5A external-priority patent/GB9622851D0/en

1996-11-01 Priority claimed from GBGB9622848.1A external-priority patent/GB9622848D0/en

1997-10-30 Application filed by Smithkline Beecham P.L.C. filed Critical Smithkline Beecham P.L.C.

1999-08-23 Publication of TR199900963T2 publication Critical patent/TR199900963T2/xx

Links

150000001875 compounds Chemical class 0.000 title abstract 5
230000000694 effects Effects 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 title abstract 2
102000004169 proteins and genes Human genes 0.000 title 1
102000016267 Leptin Human genes 0.000 abstract 8
108010092277 Leptin Proteins 0.000 abstract 8
108091027981 Response element Proteins 0.000 abstract 4
101000617830 Homo sapiens Sterol O-acyltransferase 1 Proteins 0.000 abstract 3
102100021993 Sterol O-acyltransferase 1 Human genes 0.000 abstract 3
101000697584 Streptomyces lavendulae Streptothricin acetyltransferase Proteins 0.000 abstract 3
230000001766 physiological effect Effects 0.000 abstract 2
102000000887 Transcription factor STAT Human genes 0.000 abstract 1
108050007918 Transcription factor STAT Proteins 0.000 abstract 1
239000012190 activator Substances 0.000 abstract 1
230000002508 compound effect Effects 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
230000000638 stimulation Effects 0.000 abstract 1
238000013518 transcription Methods 0.000 abstract 1
230000035897 transcription Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Immunology (AREA)
General Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Analytical Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Endocrinology (AREA)
Physics & Mathematics (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Cell Biology (AREA)
Child & Adolescent Psychology (AREA)
Obesity (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Investigating Or Analysing Biological Materials (AREA)

TR1999/00963T 1996-11-01 1997-10-30 Obez (OB) proteininin etkilerine uyan bile�iklerin tespit edilmesi i�in metot. TR199900963T2 (xx)

Applications Claiming Priority (11)

Application Number	Priority Date	Filing Date	Title
GBGB9622869.7A GB9622869D0 (en)	1996-11-01	1996-11-01	Novel method
GBGB9622850.7A GB9622850D0 (en)	1996-11-01	1996-11-01	Novel method
GBGB9622870.5A GB9622870D0 (en)	1996-11-01	1996-11-01	Novel method
GBGB9622867.1A GB9622867D0 (en)	1996-11-01	1996-11-01	Novel method
GBGB9622868.9A GB9622868D0 (en)	1996-11-01	1996-11-01	Novel method
GBGB9622866.3A GB9622866D0 (en)	1996-11-01	1996-11-01	Novel method
GBGB9622847.3A GB9622847D0 (en)	1996-11-01	1996-11-01	Novel method
GBGB9622865.5A GB9622865D0 (en)	1996-11-01	1996-11-01	Novel method
GBGB9622849.9A GB9622849D0 (en)	1996-11-01	1996-11-01	Novel method
GBGB9622851.5A GB9622851D0 (en)	1996-11-01	1996-11-01	Novel method
GBGB9622848.1A GB9622848D0 (en)	1996-11-01	1996-11-01	Novel method

Publications (1)

Publication Number	Publication Date
TR199900963T2 true TR199900963T2 (xx)	1999-08-23

Family

ID=27581686

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TR1999/00963T TR199900963T2 (xx)	1996-11-01	1997-10-30	Obez (OB) proteininin etkilerine uyan bile�iklerin tespit edilmesi i�in metot.

Country Status (13)

Country	Link
EP (1)	EP0951564A1 (cs)
JP (1)	JP2001503982A (cs)
KR (1)	KR20000053007A (cs)
AR (1)	AR010262A1 (cs)
AU (1)	AU4789297A (cs)
CA (1)	CA2270431A1 (cs)
CZ (1)	CZ149999A3 (cs)
IL (1)	IL129685A0 (cs)
NO (1)	NO992107L (cs)
NZ (1)	NZ335489A (cs)
PL (1)	PL333187A1 (cs)
TR (1)	TR199900963T2 (cs)
WO (1)	WO1998020158A1 (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1293533B1 (it) *	1997-07-14	1999-03-01	Angeletti P Ist Richerche Bio	Metodo per la selezione di molecole in grado di mimare, inibire o potenziare gli effetti della interazione tra leptina e cellule che
GB9814199D0 (en) *	1998-06-30	1998-08-26	Univ Buckingham	Novel method
EP1101112B1 (en)	1998-07-28	2004-10-06	Vlaams Interuniversitair Instituut voor Biotechnologie vzw.	Leptin-mediated gene-induction
GB9828087D0 (en) *	1998-12-18	1999-02-17	Smithkline Beecham Plc	Novel method
EP1283878B1 (en)	2000-05-22	2005-07-27	Vlaams Interuniversitair Instituut voor Biotechnologie vzw.	Receptor-based interaction trap
GB0019327D0 (en) *	2000-08-08	2000-09-27	Buchanan Baillie Hamilton Paul	Slimming system
EP1812038A1 (en)	2004-11-18	2007-08-01	VIB vzw	Fibronectin iii domain as leptin receptor antagonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2285995A (en) *	1994-04-14	1995-11-10	Ligand Pharmaceuticals Incorporated	Dna spacer regulatory elements responsive to cytokines and methods for their use
US5643748A (en) *	1994-09-14	1997-07-01	Progenitor, Inc.	HU-B1.219, a novel human hematopoietin receptor
AU5524896A (en) *	1995-03-20	1996-10-08	Institut Pasteur De Lille	Modulators of ob gene and screening methods therefor
US5712094A (en) *	1995-03-27	1998-01-27	Ligand Pharmaceuticals, Inc.	Methods for detecting modulators of cytokine action
PL323638A1 (en) *	1995-05-30	1998-04-14	Smithkline Beecham Plc	Method of detecting obesity protein modulating compounds
EP0914611A4 (en) *	1996-04-22	2002-10-16	Merck & Co Inc	TRANSACTIVATION OF LEPTIN

1997
- 1997-10-30 PL PL97333187A patent/PL333187A1/xx unknown
- 1997-10-30 TR TR1999/00963T patent/TR199900963T2/xx unknown
- 1997-10-30 JP JP52112898A patent/JP2001503982A/ja active Pending
- 1997-10-30 NZ NZ335489A patent/NZ335489A/xx unknown
- 1997-10-30 KR KR1019990703890A patent/KR20000053007A/ko not_active Withdrawn
- 1997-10-30 AU AU47892/97A patent/AU4789297A/en not_active Abandoned
- 1997-10-30 EP EP97910545A patent/EP0951564A1/en not_active Withdrawn
- 1997-10-30 WO PCT/GB1997/002988 patent/WO1998020158A1/en not_active Ceased
- 1997-10-30 IL IL12968597A patent/IL129685A0/xx unknown
- 1997-10-30 CZ CZ991499A patent/CZ149999A3/cs unknown
- 1997-10-30 CA CA002270431A patent/CA2270431A1/en not_active Abandoned
- 1997-10-31 AR ARP970105064A patent/AR010262A1/es unknown
1999
- 1999-04-30 NO NO992107A patent/NO992107L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0951564A1 (en)	1999-10-27
JP2001503982A (ja)	2001-03-27
KR20000053007A (ko)	2000-08-25
CZ149999A3 (cs)	1999-10-13
NO992107L (no)	1999-06-30
NO992107D0 (no)	1999-04-30
WO1998020158A1 (en)	1998-05-14
NZ335489A (en)	2001-01-26
AU4789297A (en)	1998-05-29
PL333187A1 (en)	1999-11-22
CA2270431A1 (en)	1998-05-14
AR010262A1 (es)	2000-06-07
IL129685A0 (en)	2000-02-29

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TR199802572T2 (xx)	1999-03-22	V�cut a��rl��n� ayarlamada elveri�li bile�ikleri tesbit i�in tarama y�ntemleri.
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ID29858A (id)	2001-10-18	Uji diagnostik tuberkulosis
KR960701367A (ko)	1996-02-24	진단 기구 및 방법(diagnostic device and method)
TR199900963T2 (xx)	1999-08-23	Obez (OB) proteininin etkilerine uyan bile�iklerin tespit edilmesi i�in metot.
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MX9709360A (es)	1998-02-28	Metodo para la deteccion de compuestos que modulan los efectos de la proteina de la obesidad.
DK0690991T3 (da)	1999-02-01	Ny antikoagulant-cofaktor-aktivitet
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NO20006541L (no)	2000-12-21	Fremgangsmåte for påvisning av en forbindelse som etterligner, potensierer eller inhiberer den fysiologiske effekten av leptin
Hoste	1986	Advantages of Enzyme Immuno Assay After Blotting in Blood Stain Grouping. Application to the Gc Subtypes
WO2000037675A3 (en)	2000-09-14	Reporter gene assay for compounds which mimic or inhibit the physiological effect of the ob-protein
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ATE214428T1 (de)	2002-03-15	Von enzymen katalysierte chemilumineszente detektion von proteinen und nukleinsäuren durch verwendung von hydroxyaryl-cyclischen diacylhydrazid-zusammensetzungen
IT9006603A1 (it)	1991-08-17	Test immunoenzimatico classe specifico per la ricerca e determinazione degli anticorpi anti-cardiolipina nel siero.
WO1999018199A3 (en)	1999-08-05	cDNAs CODING FOR HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS