NO992107L - FremgangsmÕte for pÕvisning av forbindelser som modulerer effekten av fett (OB) proteinet - Google Patents
FremgangsmÕte for pÕvisning av forbindelser som modulerer effekten av fett (OB) proteinetInfo
- Publication number
- NO992107L NO992107L NO992107A NO992107A NO992107L NO 992107 L NO992107 L NO 992107L NO 992107 A NO992107 A NO 992107A NO 992107 A NO992107 A NO 992107A NO 992107 L NO992107 L NO 992107L
- Authority
- NO
- Norway
- Prior art keywords
- cell line
- protein
- derived cell
- compound
- response element
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 230000000694 effects Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 13
- 102000016267 Leptin Human genes 0.000 abstract 9
- 108010092277 Leptin Proteins 0.000 abstract 9
- 108091027981 Response element Proteins 0.000 abstract 5
- 101000617830 Homo sapiens Sterol O-acyltransferase 1 Proteins 0.000 abstract 4
- 102100021993 Sterol O-acyltransferase 1 Human genes 0.000 abstract 4
- 101000697584 Streptomyces lavendulae Streptothricin acetyltransferase Proteins 0.000 abstract 4
- 230000001766 physiological effect Effects 0.000 abstract 3
- 108700008625 Reporter Genes Proteins 0.000 abstract 2
- 101710140204 Signal transducer and transcription activator Proteins 0.000 abstract 1
- 108050007918 Transcription factor STAT Proteins 0.000 abstract 1
- 102000000887 Transcription factor STAT Human genes 0.000 abstract 1
- 210000003016 hypothalamus Anatomy 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 230000002611 ovarian Effects 0.000 abstract 1
- 208000028591 pheochromocytoma Diseases 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 210000000229 preadipocyte Anatomy 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 210000002027 skeletal muscle Anatomy 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Endocrinology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9622869.7A GB9622869D0 (en) | 1996-11-01 | 1996-11-01 | Novel method |
| GBGB9622850.7A GB9622850D0 (en) | 1996-11-01 | 1996-11-01 | Novel method |
| GBGB9622870.5A GB9622870D0 (en) | 1996-11-01 | 1996-11-01 | Novel method |
| GBGB9622867.1A GB9622867D0 (en) | 1996-11-01 | 1996-11-01 | Novel method |
| GBGB9622868.9A GB9622868D0 (en) | 1996-11-01 | 1996-11-01 | Novel method |
| GBGB9622866.3A GB9622866D0 (en) | 1996-11-01 | 1996-11-01 | Novel method |
| GBGB9622847.3A GB9622847D0 (en) | 1996-11-01 | 1996-11-01 | Novel method |
| GBGB9622865.5A GB9622865D0 (en) | 1996-11-01 | 1996-11-01 | Novel method |
| GBGB9622849.9A GB9622849D0 (en) | 1996-11-01 | 1996-11-01 | Novel method |
| GBGB9622851.5A GB9622851D0 (en) | 1996-11-01 | 1996-11-01 | Novel method |
| GBGB9622848.1A GB9622848D0 (en) | 1996-11-01 | 1996-11-01 | Novel method |
| PCT/GB1997/002988 WO1998020158A1 (en) | 1996-11-01 | 1997-10-30 | Method for the detection of compounds that modulate the effects of the obese (ob) protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO992107D0 NO992107D0 (no) | 1999-04-30 |
| NO992107L true NO992107L (no) | 1999-06-30 |
Family
ID=27581686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO992107A NO992107L (no) | 1996-11-01 | 1999-04-30 | FremgangsmÕte for pÕvisning av forbindelser som modulerer effekten av fett (OB) proteinet |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0951564A1 (cs) |
| JP (1) | JP2001503982A (cs) |
| KR (1) | KR20000053007A (cs) |
| AR (1) | AR010262A1 (cs) |
| AU (1) | AU4789297A (cs) |
| CA (1) | CA2270431A1 (cs) |
| CZ (1) | CZ149999A3 (cs) |
| IL (1) | IL129685A0 (cs) |
| NO (1) | NO992107L (cs) |
| NZ (1) | NZ335489A (cs) |
| PL (1) | PL333187A1 (cs) |
| TR (1) | TR199900963T2 (cs) |
| WO (1) | WO1998020158A1 (cs) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1293533B1 (it) * | 1997-07-14 | 1999-03-01 | Angeletti P Ist Richerche Bio | Metodo per la selezione di molecole in grado di mimare, inibire o potenziare gli effetti della interazione tra leptina e cellule che |
| GB9814199D0 (en) * | 1998-06-30 | 1998-08-26 | Univ Buckingham | Novel method |
| EP1101112B1 (en) | 1998-07-28 | 2004-10-06 | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. | Leptin-mediated gene-induction |
| GB9828087D0 (en) * | 1998-12-18 | 1999-02-17 | Smithkline Beecham Plc | Novel method |
| EP1283878B1 (en) | 2000-05-22 | 2005-07-27 | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. | Receptor-based interaction trap |
| GB0019327D0 (en) * | 2000-08-08 | 2000-09-27 | Buchanan Baillie Hamilton Paul | Slimming system |
| EP1812038A1 (en) | 2004-11-18 | 2007-08-01 | VIB vzw | Fibronectin iii domain as leptin receptor antagonists |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2285995A (en) * | 1994-04-14 | 1995-11-10 | Ligand Pharmaceuticals Incorporated | Dna spacer regulatory elements responsive to cytokines and methods for their use |
| US5643748A (en) * | 1994-09-14 | 1997-07-01 | Progenitor, Inc. | HU-B1.219, a novel human hematopoietin receptor |
| AU5524896A (en) * | 1995-03-20 | 1996-10-08 | Institut Pasteur De Lille | Modulators of ob gene and screening methods therefor |
| US5712094A (en) * | 1995-03-27 | 1998-01-27 | Ligand Pharmaceuticals, Inc. | Methods for detecting modulators of cytokine action |
| PL323638A1 (en) * | 1995-05-30 | 1998-04-14 | Smithkline Beecham Plc | Method of detecting obesity protein modulating compounds |
| EP0914611A4 (en) * | 1996-04-22 | 2002-10-16 | Merck & Co Inc | TRANSACTIVATION OF LEPTIN |
-
1997
- 1997-10-30 PL PL97333187A patent/PL333187A1/xx unknown
- 1997-10-30 TR TR1999/00963T patent/TR199900963T2/xx unknown
- 1997-10-30 JP JP52112898A patent/JP2001503982A/ja active Pending
- 1997-10-30 NZ NZ335489A patent/NZ335489A/xx unknown
- 1997-10-30 KR KR1019990703890A patent/KR20000053007A/ko not_active Withdrawn
- 1997-10-30 AU AU47892/97A patent/AU4789297A/en not_active Abandoned
- 1997-10-30 EP EP97910545A patent/EP0951564A1/en not_active Withdrawn
- 1997-10-30 WO PCT/GB1997/002988 patent/WO1998020158A1/en not_active Ceased
- 1997-10-30 IL IL12968597A patent/IL129685A0/xx unknown
- 1997-10-30 CZ CZ991499A patent/CZ149999A3/cs unknown
- 1997-10-30 CA CA002270431A patent/CA2270431A1/en not_active Abandoned
- 1997-10-31 AR ARP970105064A patent/AR010262A1/es unknown
-
1999
- 1999-04-30 NO NO992107A patent/NO992107L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TR199900963T2 (xx) | 1999-08-23 |
| EP0951564A1 (en) | 1999-10-27 |
| JP2001503982A (ja) | 2001-03-27 |
| KR20000053007A (ko) | 2000-08-25 |
| CZ149999A3 (cs) | 1999-10-13 |
| NO992107D0 (no) | 1999-04-30 |
| WO1998020158A1 (en) | 1998-05-14 |
| NZ335489A (en) | 2001-01-26 |
| AU4789297A (en) | 1998-05-29 |
| PL333187A1 (en) | 1999-11-22 |
| CA2270431A1 (en) | 1998-05-14 |
| AR010262A1 (es) | 2000-06-07 |
| IL129685A0 (en) | 2000-02-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |