PL3445742T3 - Krystaliczny fosforan tapentadolu - Google Patents
Krystaliczny fosforan tapentadoluInfo
- Publication number
- PL3445742T3 PL3445742T3 PL17716933T PL17716933T PL3445742T3 PL 3445742 T3 PL3445742 T3 PL 3445742T3 PL 17716933 T PL17716933 T PL 17716933T PL 17716933 T PL17716933 T PL 17716933T PL 3445742 T3 PL3445742 T3 PL 3445742T3
- Authority
- PL
- Poland
- Prior art keywords
- tapentadol phosphate
- crystalline tapentadol
- crystalline
- phosphate
- tapentadol
- Prior art date
Links
- 229910019142 PO4 Inorganic materials 0.000 title 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title 1
- 239000010452 phosphate Substances 0.000 title 1
- KWTWDQCKEHXFFR-SMDDNHRTSA-N tapentadol Chemical compound CN(C)C[C@H](C)[C@@H](CC)C1=CC=CC(O)=C1 KWTWDQCKEHXFFR-SMDDNHRTSA-N 0.000 title 1
- 229960005126 tapentadol Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16166101 | 2016-04-19 | ||
| EP16166099 | 2016-04-19 | ||
| EP16170781 | 2016-05-23 | ||
| EP16170780 | 2016-05-23 | ||
| EP17716933.1A EP3445742B1 (en) | 2016-04-19 | 2017-04-18 | Crystalline tapentadol phosphate |
| PCT/EP2017/059125 WO2017182438A1 (en) | 2016-04-19 | 2017-04-18 | Crystalline tapentadol phosphate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3445742T3 true PL3445742T3 (pl) | 2020-05-18 |
Family
ID=58537027
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17716933T PL3445742T3 (pl) | 2016-04-19 | 2017-04-18 | Krystaliczny fosforan tapentadolu |
| PL20216224.4T PL3819287T3 (pl) | 2016-04-19 | 2017-04-18 | Amorficzny fosforan tapentadolu |
| PL19208228.7T PL3653599T3 (pl) | 2016-04-19 | 2017-04-18 | Krystaliczny fosforan tapentadolu |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL20216224.4T PL3819287T3 (pl) | 2016-04-19 | 2017-04-18 | Amorficzny fosforan tapentadolu |
| PL19208228.7T PL3653599T3 (pl) | 2016-04-19 | 2017-04-18 | Krystaliczny fosforan tapentadolu |
Country Status (7)
| Country | Link |
|---|---|
| EP (3) | EP3653599B1 (pl) |
| DK (3) | DK3653599T3 (pl) |
| ES (3) | ES2966219T3 (pl) |
| HR (1) | HRP20200029T1 (pl) |
| PL (3) | PL3445742T3 (pl) |
| PT (1) | PT3445742T (pl) |
| WO (1) | WO2017182438A1 (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110015955A (zh) | 2010-07-23 | 2019-07-16 | 格吕伦塔尔有限公司 | 3-(3-二甲基氨基-1-乙基-2-甲基-丙基)-苯酚的盐或共晶体 |
| EP3875077B1 (en) * | 2020-03-02 | 2023-12-13 | Grünenthal GmbH | Dosage form providing prolonged release of tapentadol phosphoric acid salt |
| PE20230105A1 (es) | 2020-03-02 | 2023-01-25 | Gruenenthal Chemie | Forma de dosificacion que proporciona liberacion prolongada de sal de acido fosforico de tapentadol |
| EP3875079A1 (en) * | 2020-03-02 | 2021-09-08 | Grünenthal GmbH | Dosage form providing prolonged release of tapentadol phosphoric acid salt |
| AU2020100442B4 (en) * | 2020-03-02 | 2020-06-18 | Grünenthal GmbH | Dosage form providing prolonged release of tapentadol phosphoric acid salt |
| ES3060121T3 (en) * | 2020-03-02 | 2026-03-25 | Gruenenthal Gmbh | Dosage form providing prolonged release of tapentadol phosphoric acid salt |
| DE202020104285U1 (de) | 2020-07-24 | 2020-12-18 | Grünenthal GmbH | Ethylcellulose-beschichtete Partikel enthaltend ein Salz aus Tapentadol und Phosphorsäure |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4426245A1 (de) | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
| PT1612203E (pt) | 2004-06-28 | 2007-08-20 | Gruenenthal Gmbh | ''formas cristalinas de cloridrato de (-) - (1r,2r) - 3 -(3-dimetilamino-l-etil - 2 - metilpropil) fenol'' |
| CN104447360B (zh) | 2007-12-07 | 2017-04-12 | 格吕伦塔尔有限公司 | (1r,2r)‑3‑(3‑二甲基氨基‑1‑乙基‑2‑甲基‑丙基)‑苯酚的结晶变体 |
| CN110015955A (zh) | 2010-07-23 | 2019-07-16 | 格吕伦塔尔有限公司 | 3-(3-二甲基氨基-1-乙基-2-甲基-丙基)-苯酚的盐或共晶体 |
| WO2012051246A1 (en) | 2010-10-12 | 2012-04-19 | Ratiopharm Gmbh | Tapentadol hydrobromide and crystalline forms thereof |
-
2017
- 2017-04-18 PL PL17716933T patent/PL3445742T3/pl unknown
- 2017-04-18 PT PT177169331T patent/PT3445742T/pt unknown
- 2017-04-18 PL PL20216224.4T patent/PL3819287T3/pl unknown
- 2017-04-18 ES ES20216224T patent/ES2966219T3/es active Active
- 2017-04-18 DK DK19208228.7T patent/DK3653599T3/da active
- 2017-04-18 EP EP19208228.7A patent/EP3653599B1/en active Active
- 2017-04-18 EP EP20216224.4A patent/EP3819287B1/en active Active
- 2017-04-18 HR HRP20200029TT patent/HRP20200029T1/hr unknown
- 2017-04-18 ES ES19208228T patent/ES2937740T3/es active Active
- 2017-04-18 EP EP17716933.1A patent/EP3445742B1/en active Active
- 2017-04-18 ES ES17716933T patent/ES2772806T3/es active Active
- 2017-04-18 WO PCT/EP2017/059125 patent/WO2017182438A1/en not_active Ceased
- 2017-04-18 PL PL19208228.7T patent/PL3653599T3/pl unknown
- 2017-04-18 DK DK17716933.1T patent/DK3445742T3/da active
- 2017-04-18 DK DK20216224.4T patent/DK3819287T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| PL3819287T3 (pl) | 2024-03-11 |
| EP3445742B1 (en) | 2019-11-13 |
| PT3445742T (pt) | 2020-02-19 |
| EP3819287B1 (en) | 2023-09-20 |
| EP3445742A1 (en) | 2019-02-27 |
| EP3653599A1 (en) | 2020-05-20 |
| PL3653599T3 (pl) | 2023-03-20 |
| EP3653599B1 (en) | 2022-12-14 |
| HRP20200029T1 (hr) | 2020-03-20 |
| ES2966219T3 (es) | 2024-04-19 |
| EP3819287A1 (en) | 2021-05-12 |
| WO2017182438A1 (en) | 2017-10-26 |
| DK3445742T3 (da) | 2020-02-24 |
| DK3653599T3 (da) | 2023-01-30 |
| ES2772806T3 (es) | 2020-07-08 |
| DK3819287T3 (da) | 2023-12-18 |
| ES2937740T3 (es) | 2023-03-30 |
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