PL3653599T3 - Krystaliczny fosforan tapentadolu - Google Patents
Krystaliczny fosforan tapentadoluInfo
- Publication number
- PL3653599T3 PL3653599T3 PL19208228.7T PL19208228T PL3653599T3 PL 3653599 T3 PL3653599 T3 PL 3653599T3 PL 19208228 T PL19208228 T PL 19208228T PL 3653599 T3 PL3653599 T3 PL 3653599T3
- Authority
- PL
- Poland
- Prior art keywords
- tapentadol phosphate
- crystalline tapentadol
- crystalline
- phosphate
- tapentadol
- Prior art date
Links
- 229910019142 PO4 Inorganic materials 0.000 title 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title 1
- 239000010452 phosphate Substances 0.000 title 1
- KWTWDQCKEHXFFR-SMDDNHRTSA-N tapentadol Chemical compound CN(C)C[C@H](C)[C@@H](CC)C1=CC=CC(O)=C1 KWTWDQCKEHXFFR-SMDDNHRTSA-N 0.000 title 1
- 229960005126 tapentadol Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16166101 | 2016-04-19 | ||
| EP16166099 | 2016-04-19 | ||
| EP16170780 | 2016-05-23 | ||
| EP16170781 | 2016-05-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3653599T3 true PL3653599T3 (pl) | 2023-03-20 |
Family
ID=58537027
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17716933T PL3445742T3 (pl) | 2016-04-19 | 2017-04-18 | Krystaliczny fosforan tapentadolu |
| PL20216224.4T PL3819287T3 (pl) | 2016-04-19 | 2017-04-18 | Amorficzny fosforan tapentadolu |
| PL19208228.7T PL3653599T3 (pl) | 2016-04-19 | 2017-04-18 | Krystaliczny fosforan tapentadolu |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17716933T PL3445742T3 (pl) | 2016-04-19 | 2017-04-18 | Krystaliczny fosforan tapentadolu |
| PL20216224.4T PL3819287T3 (pl) | 2016-04-19 | 2017-04-18 | Amorficzny fosforan tapentadolu |
Country Status (7)
| Country | Link |
|---|---|
| EP (3) | EP3653599B1 (pl) |
| DK (3) | DK3653599T3 (pl) |
| ES (3) | ES2772806T3 (pl) |
| HR (1) | HRP20200029T1 (pl) |
| PL (3) | PL3445742T3 (pl) |
| PT (1) | PT3445742T (pl) |
| WO (1) | WO2017182438A1 (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2860676T3 (es) | 2010-07-23 | 2021-10-05 | Gruenenthal Gmbh | Sales o cocristales de 3- (3-dimetilamino-1-etil-2-metil-propil) -fenol |
| EP3875079A1 (en) * | 2020-03-02 | 2021-09-08 | Grünenthal GmbH | Dosage form providing prolonged release of tapentadol phosphoric acid salt |
| PL3875077T3 (pl) * | 2020-03-02 | 2024-03-11 | Grünenthal GmbH | Postać dawkowania zapewniająca przedłużone uwalnianie soli kwasu fosforowego tapentadolu |
| WO2021175773A1 (en) | 2020-03-02 | 2021-09-10 | Grünenthal GmbH | Dosage form providing prolonged release of tapentadol phosphoric acid salt |
| AU2020100442B4 (en) * | 2020-03-02 | 2020-06-18 | Grünenthal GmbH | Dosage form providing prolonged release of tapentadol phosphoric acid salt |
| ES3060121T3 (en) * | 2020-03-02 | 2026-03-25 | Gruenenthal Gmbh | Dosage form providing prolonged release of tapentadol phosphoric acid salt |
| DE202020104285U1 (de) | 2020-07-24 | 2020-12-18 | Grünenthal GmbH | Ethylcellulose-beschichtete Partikel enthaltend ein Salz aus Tapentadol und Phosphorsäure |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4426245A1 (de) | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
| DK1612203T3 (da) | 2004-06-28 | 2007-12-03 | Gruenenthal Gmbh | Krystallinske former af (-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenolhydrochlorid |
| CN101939287B (zh) | 2007-12-07 | 2014-10-22 | 格吕伦塔尔有限公司 | (1r,2r)-3-(3-二甲基氨基-1-乙基-2-甲基-丙基)-苯酚的结晶变体 |
| ES2860676T3 (es) | 2010-07-23 | 2021-10-05 | Gruenenthal Gmbh | Sales o cocristales de 3- (3-dimetilamino-1-etil-2-metil-propil) -fenol |
| WO2012051246A1 (en) | 2010-10-12 | 2012-04-19 | Ratiopharm Gmbh | Tapentadol hydrobromide and crystalline forms thereof |
-
2017
- 2017-04-18 PT PT177169331T patent/PT3445742T/pt unknown
- 2017-04-18 EP EP19208228.7A patent/EP3653599B1/en active Active
- 2017-04-18 ES ES17716933T patent/ES2772806T3/es active Active
- 2017-04-18 DK DK19208228.7T patent/DK3653599T3/da active
- 2017-04-18 ES ES19208228T patent/ES2937740T3/es active Active
- 2017-04-18 PL PL17716933T patent/PL3445742T3/pl unknown
- 2017-04-18 ES ES20216224T patent/ES2966219T3/es active Active
- 2017-04-18 EP EP17716933.1A patent/EP3445742B1/en active Active
- 2017-04-18 DK DK20216224.4T patent/DK3819287T3/da active
- 2017-04-18 PL PL20216224.4T patent/PL3819287T3/pl unknown
- 2017-04-18 PL PL19208228.7T patent/PL3653599T3/pl unknown
- 2017-04-18 EP EP20216224.4A patent/EP3819287B1/en active Active
- 2017-04-18 HR HRP20200029TT patent/HRP20200029T1/hr unknown
- 2017-04-18 WO PCT/EP2017/059125 patent/WO2017182438A1/en not_active Ceased
- 2017-04-18 DK DK17716933.1T patent/DK3445742T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017182438A1 (en) | 2017-10-26 |
| EP3819287B1 (en) | 2023-09-20 |
| EP3653599B1 (en) | 2022-12-14 |
| EP3445742A1 (en) | 2019-02-27 |
| ES2772806T3 (es) | 2020-07-08 |
| DK3653599T3 (da) | 2023-01-30 |
| ES2966219T3 (es) | 2024-04-19 |
| PT3445742T (pt) | 2020-02-19 |
| PL3445742T3 (pl) | 2020-05-18 |
| ES2937740T3 (es) | 2023-03-30 |
| EP3819287A1 (en) | 2021-05-12 |
| EP3653599A1 (en) | 2020-05-20 |
| DK3445742T3 (da) | 2020-02-24 |
| DK3819287T3 (da) | 2023-12-18 |
| HRP20200029T1 (hr) | 2020-03-20 |
| EP3445742B1 (en) | 2019-11-13 |
| PL3819287T3 (pl) | 2024-03-11 |
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