PL353870A1 - Sposób wytwarzania zaleplonu - Google Patents

Sposób wytwarzania zaleplonu

Info

Publication number: PL353870A1
Authority: PL; Poland
Prior art keywords: zaleplon; ethyl; reaction; formic acid; zaleplone
Prior art date: 2002-05-14

Application number

PL02353870A

Other languages

English (en)

Other versions

PL207322B1 (pl

Inventor

Maciej Wieczorek

Tomasz Stawiński

Monika Korycińska

Original Assignee

ADAMED Sp.z o.o.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-14

Filing date

2002-05-14

Publication date

2003-11-17

2002-05-14 Application filed by ADAMED Sp.z o.o. filed Critical ADAMED Sp.z o.o.

2002-05-14 Priority to PL353870A priority Critical patent/PL207322B1/pl

2003-05-12 Priority to AT03750002T priority patent/ATE342903T1/de

2003-05-12 Priority to ES03750002T priority patent/ES2275110T3/es

2003-05-12 Priority to RU2004136843/04A priority patent/RU2004136843A/ru

2003-05-12 Priority to BR0304837-3A priority patent/BR0304837A/pt

2003-05-12 Priority to US10/514,045 priority patent/US7057041B2/en

2003-05-12 Priority to CA002482545A priority patent/CA2482545A1/en

2003-05-12 Priority to AU2003243061A priority patent/AU2003243061A1/en

2003-05-12 Priority to DE60309159T priority patent/DE60309159D1/de

2003-05-12 Priority to EP03750002A priority patent/EP1506199B1/en

2003-05-12 Priority to PCT/PL2003/000043 priority patent/WO2003095456A1/en

2003-11-17 Publication of PL353870A1 publication Critical patent/PL353870A1/pl

2003-12-05 Priority to UA20041109259A priority patent/UA77292C2/uk

2004-01-05 Priority to NO20040029A priority patent/NO20040029L/no

2010-11-30 Publication of PL207322B1 publication Critical patent/PL207322B1/pl

Links

238000000034 method Methods 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 4
OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 2
235000019253 formic acid Nutrition 0.000 abstract 2
HUNXMJYCHXQEGX-UHFFFAOYSA-N zaleplon Chemical compound CCN(C(C)=O)C1=CC=CC(C=2N3N=CC(=C3N=CC=2)C#N)=C1 HUNXMJYCHXQEGX-UHFFFAOYSA-N 0.000 abstract 2
229960004010 zaleplon Drugs 0.000 abstract 2
FFNKBQRKZRMYCL-UHFFFAOYSA-N 5-amino-1h-pyrazole-4-carbonitrile Chemical compound NC1=NNC=C1C#N FFNKBQRKZRMYCL-UHFFFAOYSA-N 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
230000000949 anxiolytic effect Effects 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
239000003158 myorelaxant agent Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
210000002027 skeletal muscle Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PL353870A 2002-05-14 2002-05-14 Sposób wytwarzania zaleplonu PL207322B1 (pl)

Priority Applications (13)

Application Number	Priority Date	Filing Date	Title
PL353870A PL207322B1 (pl)	2002-05-14	2002-05-14	Sposób wytwarzania zaleplonu
AU2003243061A AU2003243061A1 (en)	2002-05-14	2003-05-12	A process for the preparation of zaleplon
DE60309159T DE60309159D1 (de)	2002-05-14	2003-05-12	Verfahren zur herstellung von zaleplon
RU2004136843/04A RU2004136843A (ru)	2002-05-14	2003-05-12	Процесс получения залеплона
BR0304837-3A BR0304837A (pt)	2002-05-14	2003-05-12	Processo para a preparação de n-[3-(3-ciano-pirazol[1,5-a]pirimidin-7-il)fenil]-n-etilace tamida) (zaleplon)
US10/514,045 US7057041B2 (en)	2002-05-14	2003-05-12	Process for the preparation of zaleplon
CA002482545A CA2482545A1 (en)	2002-05-14	2003-05-12	A process for the preparation of zaleplon
AT03750002T ATE342903T1 (de)	2002-05-14	2003-05-12	Verfahren zur herstellung von zaleplon
ES03750002T ES2275110T3 (es)	2002-05-14	2003-05-12	Procedimiento para la preparacion de zaleplon.
EP03750002A EP1506199B1 (en)	2002-05-14	2003-05-12	A process for the preparation of zaleplon
PCT/PL2003/000043 WO2003095456A1 (en)	2002-05-14	2003-05-12	A process for the preparation of zaleplon
UA20041109259A UA77292C2 (uk)	2002-05-14	2003-12-05	Спосіб одержання залеплону
NO20040029A NO20040029L (no)	2002-05-14	2004-01-05	Fremgangsmåte for fremstillingen av zaleplon

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PL353870A PL207322B1 (pl)	2002-05-14	2002-05-14	Sposób wytwarzania zaleplonu

Publications (2)

Publication Number	Publication Date
PL353870A1 true PL353870A1 (pl)	2003-11-17
PL207322B1 PL207322B1 (pl)	2010-11-30

Family

ID=29417606

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL353870A PL207322B1 (pl)	2002-05-14	2002-05-14	Sposób wytwarzania zaleplonu

Country Status (13)

Country	Link
US (1)	US7057041B2 (pl)
EP (1)	EP1506199B1 (pl)
AT (1)	ATE342903T1 (pl)
AU (1)	AU2003243061A1 (pl)
BR (1)	BR0304837A (pl)
CA (1)	CA2482545A1 (pl)
DE (1)	DE60309159D1 (pl)
ES (1)	ES2275110T3 (pl)
NO (1)	NO20040029L (pl)
PL (1)	PL207322B1 (pl)
RU (1)	RU2004136843A (pl)
UA (1)	UA77292C2 (pl)
WO (1)	WO2003095456A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE02778962T1 (de) *	2001-06-12	2005-02-10	Biogal Gyogyszergyar Rt.	VERFAHREN ZUR HERSTELLUNG VON N ç3 (3 CYANOPYRAZOLOç1,5 A!PYRIMIDIN 7 YL)PHENYL!-N-ETHYLACETAMID (ZALEPLON)
PL374176A1 (pl)	2001-08-01	2005-10-03	Biogal Gyogyszergyar Rt	Sposób oczyszczania N-[3-(3-cyjanopirazolo [1,5-a] pirymidyn-7-ylo)fenylo]-N-etyloacetamidu (zaleplonu) i krystaliczne formy zaleplonu wytworzone tymsposobem
HUP0400325A3 (en) *	2004-02-02	2005-11-28	Richter Gedeon Vegyeszet	Pure n-[3-(-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-n-ethyl-acetamide, process for its preparation and intermediates
US9618162B2 (en)	2014-04-25	2017-04-11	Cree, Inc.	LED lamp

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4626538A (en) *	1983-06-23	1986-12-02	American Cyanamid Company	[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines
US5714607A (en) *	1995-12-01	1998-02-03	American Cyanamid Company	Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide
DE02778962T1 (de) *	2001-06-12	2005-02-10	Biogal Gyogyszergyar Rt.	VERFAHREN ZUR HERSTELLUNG VON N ç3 (3 CYANOPYRAZOLOç1,5 A!PYRIMIDIN 7 YL)PHENYL!-N-ETHYLACETAMID (ZALEPLON)

2002
- 2002-05-14 PL PL353870A patent/PL207322B1/pl unknown
2003
- 2003-05-12 US US10/514,045 patent/US7057041B2/en not_active Expired - Fee Related
- 2003-05-12 RU RU2004136843/04A patent/RU2004136843A/ru not_active Application Discontinuation
- 2003-05-12 AT AT03750002T patent/ATE342903T1/de active
- 2003-05-12 ES ES03750002T patent/ES2275110T3/es not_active Expired - Lifetime
- 2003-05-12 CA CA002482545A patent/CA2482545A1/en not_active Abandoned
- 2003-05-12 EP EP03750002A patent/EP1506199B1/en not_active Expired - Lifetime
- 2003-05-12 BR BR0304837-3A patent/BR0304837A/pt not_active Application Discontinuation
- 2003-05-12 AU AU2003243061A patent/AU2003243061A1/en not_active Abandoned
- 2003-05-12 DE DE60309159T patent/DE60309159D1/de not_active Expired - Lifetime
- 2003-05-12 WO PCT/PL2003/000043 patent/WO2003095456A1/en not_active Ceased
- 2003-12-05 UA UA20041109259A patent/UA77292C2/uk unknown
2004
- 2004-01-05 NO NO20040029A patent/NO20040029L/no unknown

Also Published As

Publication number	Publication date
PL207322B1 (pl)	2010-11-30
CA2482545A1 (en)	2003-11-20
ES2275110T3 (es)	2007-06-01
WO2003095456A1 (en)	2003-11-20
US7057041B2 (en)	2006-06-06
RU2004136843A (ru)	2005-07-20
US20050234237A1 (en)	2005-10-20
BR0304837A (pt)	2004-08-17
EP1506199A1 (en)	2005-02-16
NO20040029L (no)	2004-01-05
UA77292C2 (uk)	2006-11-15
ATE342903T1 (de)	2006-11-15
EP1506199B1 (en)	2006-10-18
AU2003243061A1 (en)	2003-11-11
DE60309159D1 (de)	2006-11-30

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