PL357099A1 - Pochodne mocznika 2-benzotiazolilu oraz ich zastosowanie jako inhibitory kinazy białkowej - Google Patents
Pochodne mocznika 2-benzotiazolilu oraz ich zastosowanie jako inhibitory kinazy białkowejInfo
- Publication number
- PL357099A1 PL357099A1 PL01357099A PL35709901A PL357099A1 PL 357099 A1 PL357099 A1 PL 357099A1 PL 01357099 A PL01357099 A PL 01357099A PL 35709901 A PL35709901 A PL 35709901A PL 357099 A1 PL357099 A1 PL 357099A1
- Authority
- PL
- Poland
- Prior art keywords
- protein kinase
- kinase inhibitors
- urea derivatives
- benzothiazolyl urea
- benzothiazolyl
- Prior art date
Links
- -1 2-benzothiazolyl urea derivatives Chemical class 0.000 title 1
- 229940045988 antineoplastic drug protein kinase inhibitors Drugs 0.000 title 1
- 239000003909 protein kinase inhibitor Substances 0.000 title 1
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- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18084100P | 2000-02-07 | 2000-02-07 | |
| PCT/US2001/003803 WO2001057008A1 (en) | 2000-02-07 | 2001-02-06 | 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors |
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| PL357099A1 true PL357099A1 (pl) | 2004-07-12 |
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| PL01357099A PL357099A1 (pl) | 2000-02-07 | 2001-02-06 | Pochodne mocznika 2-benzotiazolilu oraz ich zastosowanie jako inhibitory kinazy białkowej |
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| US (1) | US7091227B2 (pl) |
| EP (1) | EP1254123A1 (pl) |
| JP (1) | JP2003521543A (pl) |
| KR (1) | KR20020084116A (pl) |
| CN (1) | CN1422262A (pl) |
| AR (1) | AR030189A1 (pl) |
| AU (1) | AU2001236698A1 (pl) |
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| HU (1) | HUP0300359A2 (pl) |
| IL (1) | IL151045A0 (pl) |
| MX (1) | MXPA02007632A (pl) |
| NO (1) | NO20023713L (pl) |
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| IL300090A (en) | 2020-07-24 | 2023-03-01 | Genzyme Corp | Pharmaceutical preparations containing VENGLUSTAT |
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| WO2022059778A1 (ja) * | 2020-09-18 | 2022-03-24 | カルナバイオサイエンス株式会社 | 環状ウレア誘導体 |
| WO2023008472A1 (ja) * | 2021-07-28 | 2023-02-02 | カルナバイオサイエンス株式会社 | 新規ベンゾチアゾール誘導体 |
| CZ310416B6 (cs) * | 2023-12-15 | 2025-05-28 | Univerzita Hradec Králové | 1-(3-Chlor-4-hydroxyfenyl)-3-(6-((trifluormethyl)thio)benzo[d]thiazol-2-yl)močovina pro použití pro léčbu rakoviny |
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| CH505543A (de) * | 1968-11-01 | 1971-04-15 | Ciba Geigy Ag | Schädlingsbekämpfungsmittel |
| US3810988A (en) * | 1968-11-01 | 1974-05-14 | Ciba Geigy Ag | Control of phytopathogenic fungi with n-benzothiazae-2-yl n-{40 {11 propylure |
| JPS53124265A (en) | 1977-04-06 | 1978-10-30 | Nippon Tokushu Noyaku Seizo Kk | Urea or thiourea type compounds, their preparation and insecticides contaning the same as active agent |
| JPS57175189A (en) | 1981-04-21 | 1982-10-28 | Kyowa Hakko Kogyo Co Ltd | Benzothiazole derivative and its preparation |
| US4966849A (en) | 1985-09-20 | 1990-10-30 | President And Fellows Of Harvard College | CDNA and genes for human angiogenin (angiogenesis factor) and methods of expression |
| JPS62187842A (ja) | 1985-10-25 | 1987-08-17 | Konishiroku Photo Ind Co Ltd | ハロゲン化銀写真感光材料 |
| US5217999A (en) | 1987-12-24 | 1993-06-08 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Styryl compounds which inhibit EGF receptor protein tyrosine kinase |
| ES2064101T3 (es) | 1990-04-02 | 1995-01-16 | Pfizer | Compuestos de acido bencilfosfonico inhibidores de la quinasa de tirosina. |
| US5302606A (en) | 1990-04-16 | 1994-04-12 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Styryl-substituted pyridyl compounds which inhibit EGF receptor tyrosine kinase |
| DE69222637T2 (de) | 1991-05-10 | 1998-02-26 | Rhone Poulenc Rorer Int | Bis mono- und bicyclische aryl- und heteroarylderivate mit inhibierender wirkung auf die egf und/oder pdgf-rezeptor tyrosinkinase |
| JPH06503095A (ja) | 1991-05-29 | 1994-04-07 | ファイザー・インコーポレーテッド | 三環式ポリヒドロキシ系のチロシンキナーゼ阻害薬 |
| AU661533B2 (en) | 1992-01-20 | 1995-07-27 | Astrazeneca Ab | Quinazoline derivatives |
| EP0654024A1 (en) | 1992-08-06 | 1995-05-24 | Warner-Lambert Company | 2-thioindoles (selenoindoles) and related disulfides (selenides) which inhibit protein tyrosine kinases and which have antitumor properties |
| US5330992A (en) | 1992-10-23 | 1994-07-19 | Sterling Winthrop Inc. | 1-cyclopropyl-4-pyridyl-quinolinones |
| KR100335584B1 (ko) | 1992-10-28 | 2002-11-29 | 제넨테크, 인코포레이티드 | 혈관내피세포성장인자에대한길항제 |
| GB9226855D0 (en) | 1992-12-23 | 1993-02-17 | Erba Carlo Spa | Vinylene-azaindole derivatives and process for their preparation |
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| EP0888310B1 (en) | 1996-03-15 | 2005-09-07 | AstraZeneca AB | Cinnoline derivatives and use as medicine |
| CA2253608A1 (en) | 1996-05-01 | 1997-11-06 | Louis Vignati | Therapeutic treatment for vegf related diseases |
| UA54427C2 (uk) | 1996-05-01 | 2003-03-17 | Елі Ліллі Енд Компані | Спосіб лікування очних захворювань, які пов'язані з фактором васкулярного ендотеліального росту |
| GB9707800D0 (en) | 1996-05-06 | 1997-06-04 | Zeneca Ltd | Chemical compounds |
| TW513418B (en) * | 1996-07-31 | 2002-12-11 | Otsuka Pharma Co Ltd | Thiazole derivatives, their production and use |
| EP0956339B1 (en) | 1996-08-23 | 2005-10-12 | Ludwig Institute For Cancer Research | Recombinant vascular endothelial cell growth factor d (vegf-d) |
| US6093742A (en) * | 1997-06-27 | 2000-07-25 | Vertex Pharmaceuticals, Inc. | Inhibitors of p38 |
| JPH11130761A (ja) | 1997-10-24 | 1999-05-18 | Otsuka Pharmaceut Co Ltd | ベンゾチアゾール誘導体 |
| NZ503491A (en) * | 1997-11-10 | 2002-08-28 | Bristol Myers Squibb Co | 2-substituted amino-1,3-benzothiazole derivatives useful as protein tyrosine kinase inhibitors |
| JPH11222431A (ja) | 1998-01-30 | 1999-08-17 | Otsuka Pharmaceut Co Ltd | 医薬組成物 |
| EP1199306B1 (en) * | 1999-07-26 | 2005-12-07 | Banyu Pharmaceutical Co., Ltd. | Biarylurea derivatives |
-
2001
- 2001-02-06 PL PL01357099A patent/PL357099A1/pl not_active Application Discontinuation
- 2001-02-06 IL IL15104501A patent/IL151045A0/xx unknown
- 2001-02-06 US US09/777,554 patent/US7091227B2/en not_active Expired - Lifetime
- 2001-02-06 CN CN01807734A patent/CN1422262A/zh active Pending
- 2001-02-06 BR BR0108085-7A patent/BR0108085A/pt not_active Application Discontinuation
- 2001-02-06 JP JP2001556858A patent/JP2003521543A/ja not_active Withdrawn
- 2001-02-06 MX MXPA02007632A patent/MXPA02007632A/es unknown
- 2001-02-06 WO PCT/US2001/003803 patent/WO2001057008A1/en not_active Ceased
- 2001-02-06 CA CA002398754A patent/CA2398754A1/en not_active Abandoned
- 2001-02-06 SK SK1271-2002A patent/SK12712002A3/sk unknown
- 2001-02-06 KR KR1020027010188A patent/KR20020084116A/ko not_active Withdrawn
- 2001-02-06 HU HU0300359A patent/HUP0300359A2/hu unknown
- 2001-02-06 EP EP01908878A patent/EP1254123A1/en not_active Withdrawn
- 2001-02-06 AU AU2001236698A patent/AU2001236698A1/en not_active Abandoned
- 2001-02-07 AR ARP010100543A patent/AR030189A1/es unknown
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2002
- 2002-08-05 ZA ZA200206235A patent/ZA200206235B/en unknown
- 2002-08-06 NO NO20023713A patent/NO20023713L/no not_active Application Discontinuation
- 2002-09-04 BG BG107062A patent/BG107062A/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BG107062A (bg) | 2003-04-30 |
| JP2003521543A (ja) | 2003-07-15 |
| BR0108085A (pt) | 2003-03-18 |
| US20030153568A1 (en) | 2003-08-14 |
| US7091227B2 (en) | 2006-08-15 |
| NO20023713L (no) | 2002-10-04 |
| NO20023713D0 (no) | 2002-08-06 |
| MXPA02007632A (es) | 2004-08-23 |
| AR030189A1 (es) | 2003-08-13 |
| HUP0300359A2 (hu) | 2003-06-28 |
| SK12712002A3 (sk) | 2003-02-04 |
| ZA200206235B (en) | 2004-02-13 |
| CN1422262A (zh) | 2003-06-04 |
| AU2001236698A1 (en) | 2001-08-14 |
| IL151045A0 (en) | 2003-04-10 |
| KR20020084116A (ko) | 2002-11-04 |
| EP1254123A1 (en) | 2002-11-06 |
| CA2398754A1 (en) | 2001-08-09 |
| WO2001057008A1 (en) | 2001-08-09 |
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