PL3581650T3 - Zmutowany polipeptyd czynnika ix, jego zastosowania i sposób jego wytwarzania - Google Patents

Zmutowany polipeptyd czynnika ix, jego zastosowania i sposób jego wytwarzania

Info

Publication number
PL3581650T3
PL3581650T3 PL19174517.3T PL19174517T PL3581650T3 PL 3581650 T3 PL3581650 T3 PL 3581650T3 PL 19174517 T PL19174517 T PL 19174517T PL 3581650 T3 PL3581650 T3 PL 3581650T3
Authority
PL
Poland
Prior art keywords
polypeptide
production
mutated factor
mutated
factor
Prior art date
Application number
PL19174517.3T
Other languages
English (en)
Inventor
Paolo Simioni
Original Assignee
Uniqure Biopharma B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41397565&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3581650(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from ITBO2008A000564A external-priority patent/IT1394177B1/it
Priority claimed from ITBO2009A000275A external-priority patent/IT1395980B1/it
Application filed by Uniqure Biopharma B.V. filed Critical Uniqure Biopharma B.V.
Publication of PL3581650T3 publication Critical patent/PL3581650T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL19174517.3T 2008-09-15 2009-09-15 Zmutowany polipeptyd czynnika ix, jego zastosowania i sposób jego wytwarzania PL3581650T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITBO2008A000564A IT1394177B1 (it) 2008-09-15 2008-09-15 Polipeptide fattore ix modificato, sue utilizzazioni e metodo per la sua produzione
ITBO2009A000275A IT1395980B1 (it) 2009-05-06 2009-05-06 Polipeptide fattore ix modificato, sue utilizzazioni e metodo per la sua produzione

Publications (1)

Publication Number Publication Date
PL3581650T3 true PL3581650T3 (pl) 2023-05-22

Family

ID=41397565

Family Applications (3)

Application Number Title Priority Date Filing Date
PL09748260T PL2337849T3 (pl) 2008-09-15 2009-09-15 Zmutowany polipeptyd czynnika ix, jego zastosowania i sposób jego otrzymywania
PL21200005.3T PL4032979T3 (pl) 2008-09-15 2009-09-15 Mutant polipeptydu czynnika ix, jego zastosowania i sposób jego otrzymywania
PL19174517.3T PL3581650T3 (pl) 2008-09-15 2009-09-15 Zmutowany polipeptyd czynnika ix, jego zastosowania i sposób jego wytwarzania

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PL09748260T PL2337849T3 (pl) 2008-09-15 2009-09-15 Zmutowany polipeptyd czynnika ix, jego zastosowania i sposób jego otrzymywania
PL21200005.3T PL4032979T3 (pl) 2008-09-15 2009-09-15 Mutant polipeptydu czynnika ix, jego zastosowania i sposób jego otrzymywania

Country Status (20)

Country Link
US (13) US9249405B2 (pl)
EP (5) EP3581650B1 (pl)
CA (1) CA2737094C (pl)
CY (2) CY1125885T1 (pl)
DK (2) DK3581650T3 (pl)
ES (3) ES2687038T3 (pl)
FI (5) FI3581650T3 (pl)
FR (4) FR23C1028I1 (pl)
HK (1) HK1244507A1 (pl)
HR (2) HRP20230259T1 (pl)
HU (6) HUE061345T2 (pl)
LT (5) LT3581650T (pl)
LU (1) LUC00311I2 (pl)
NO (2) NO2023029I1 (pl)
PL (3) PL2337849T3 (pl)
PT (1) PT3581650T (pl)
SI (1) SI3581650T1 (pl)
SM (2) SMT201800468T1 (pl)
TR (1) TR201813067T4 (pl)
WO (1) WO2010029178A1 (pl)

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US10370431B2 (en) 2013-02-15 2019-08-06 Bioverativ Therapeutics Inc. Optimized factor VIII gene
US11008561B2 (en) 2014-06-30 2021-05-18 Bioverativ Therapeutics Inc. Optimized factor IX gene
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JP2021523198A (ja) 2018-05-14 2021-09-02 ビオマリン プハルマセウトイカル インコーポレイテッド 幼若対象におけるａａｖベクターの安定的発現
CA3109579A1 (en) * 2018-08-20 2020-02-27 Ucl Business Ltd Factor ix encoding nucleotides
GB201813528D0 (en) 2018-08-20 2018-10-03 Ucl Business Plc Factor IX encoding nucleotides
US10842885B2 (en) 2018-08-20 2020-11-24 Ucl Business Ltd Factor IX encoding nucleotides
UY38389A (es) * 2018-09-27 2020-04-30 Sigilon Therapeutics Inc Dispositivos implantables para terapia celular y métodos relacionados
JP7578590B2 (ja) 2018-10-18 2024-11-06 インテリア セラピューティクス，インコーポレーテッド 第ｉｘ因子を発現するための組成物及び方法
JP7803014B2 (ja) 2019-09-30 2026-01-21 バイオベラティブ セラピューティクス インコーポレイテッド レンチウイルスベクター製剤
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Also Published As

Publication number Publication date
DK2337849T3 (en) 2018-10-01
CY2023016I1 (el) 2024-02-16
EP2337849B1 (en) 2018-06-13
HUE067487T2 (hu) 2024-10-28
EP3581650A2 (en) 2019-12-18
US20210214704A1 (en) 2021-07-15
US20160122740A1 (en) 2016-05-05
FR25C1004I1 (fr) 2025-02-28
CA2737094A1 (en) 2010-03-18
NO2025007I1 (no) 2025-01-21
PL4032979T3 (pl) 2024-09-30
FR24C1040I1 (fr) 2024-12-06
FIC20250007I1 (fi) 2025-01-22
US10465180B2 (en) 2019-11-05
EP3581650A3 (en) 2020-03-25
CY2023016I2 (el) 2024-02-16
HUE061345T2 (hu) 2023-06-28
HRP20181442T1 (hr) 2018-12-14
LTPA2023521I1 (pl) 2023-08-25
US9249405B2 (en) 2016-02-02
FIC20230026I1 (fi) 2023-07-25
HK1244507A1 (en) 2018-08-10
HUS2300024I1 (hu) 2023-08-28
LTPA2024530I1 (pl) 2024-11-25
EP4032979C0 (en) 2024-05-01
FR24C1041I1 (fr) 2024-12-06
US20200190498A1 (en) 2020-06-18
FIC20240037I1 (fi) 2024-10-30
WO2010029178A1 (en) 2010-03-18
NO2023029I1 (no) 2023-07-31
EP3252157A1 (en) 2017-12-06
US20200231958A1 (en) 2020-07-23
DK3581650T3 (da) 2023-03-13
US20200199564A1 (en) 2020-06-25
US20220090042A1 (en) 2022-03-24
EP4032979A1 (en) 2022-07-27
EP2337849A1 (en) 2011-06-29
USRE50288E1 (en) 2025-02-04
FI3581650T3 (fi) 2023-03-23
HRP20230259T1 (hr) 2023-04-28
CY1125885T1 (el) 2024-02-16
ES2940323T3 (es) 2023-05-05
EP4219547A3 (en) 2023-10-18
EP3581650B1 (en) 2022-12-28
US20220002702A1 (en) 2022-01-06
US9982248B2 (en) 2018-05-29
US20170355973A1 (en) 2017-12-14
US20110244550A1 (en) 2011-10-06
EP4219547A2 (en) 2023-08-02
US20250179462A1 (en) 2025-06-05
US20210238573A1 (en) 2021-08-05
LTPA2024529I1 (pl) 2024-12-10
US20180258413A1 (en) 2018-09-13
FIC20240036I1 (fi) 2024-10-29
LUC00311I2 (pl) 2026-02-02
LT3581650T (lt) 2023-05-10
SMT201800468T1 (it) 2018-11-09
HUS2400037I1 (hu) 2024-11-28
ES2985035T3 (es) 2024-11-04
EP4032979B1 (en) 2024-05-01
TR201813067T4 (tr) 2018-09-21
SI3581650T1 (sl) 2023-06-30
ES2687038T3 (es) 2018-10-23
HUS2500006I1 (hu) 2025-02-28
PT3581650T (pt) 2023-03-08
HUS2400036I1 (hu) 2024-11-28
LTPA2025503I1 (pl) 2025-02-10
SMT202300084T1 (it) 2023-05-12
PL2337849T3 (pl) 2018-11-30
CA2737094F (en) 2010-03-18
CA2737094C (en) 2018-02-20
FR23C1028I1 (fr) 2023-10-06

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