PL360087A1 - Sposób wytwarzania pochodnych bakatyny III - Google Patents

Sposób wytwarzania pochodnych bakatyny III

Info

Publication number: PL360087A1
Authority: PL; Poland
Prior art keywords: preparation; baccatin iii; iii derivatives; derivatives; beta
Prior art date: 2000-08-10

Application number

PL36008701A

Other languages

English (en)

Other versions

PL200868B1 (pl

Inventor

Alessandro Pontiroli

Ezio Bombardelli

Original Assignee

Indena S.P.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-10

Filing date

2001-07-27

Publication date

2004-09-06

2001-07-27 Application filed by Indena S.P.A. filed Critical Indena S.P.A.

2004-09-06 Publication of PL360087A1 publication Critical patent/PL360087A1/pl

2009-02-27 Publication of PL200868B1 publication Critical patent/PL200868B1/pl

Links

238000000034 method Methods 0.000 title abstract 2
OVMSOCFBDVBLFW-VHLOTGQHSA-N 5beta,20-epoxy-1,7beta,13alpha-trihydroxy-9-oxotax-11-ene-2alpha,4alpha,10beta-triyl 4,10-diacetate 2-benzoate Chemical class O([C@@H]1[C@@]2(C[C@H](O)C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)O)C(=O)C1=CC=CC=C1 OVMSOCFBDVBLFW-VHLOTGQHSA-N 0.000 title 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Epoxy Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Peptides Or Proteins (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

PL360087A 2000-08-10 2001-07-27 Sposób wytwarzania 1,14-węglanu 14ß-hydroksy-10-deacetylobakatyny III oraz związki pośrednie PL200868B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2000MI001869A IT1318678B1 (it)	2000-08-10	2000-08-10	Procedimento per la preparazione di derivati della baccatina iii.
PCT/EP2001/008730 WO2002012215A1 (en)	2000-08-10	2001-07-27	Process for the preparation of baccatin iii derivatives

Publications (2)

Publication Number	Publication Date
PL360087A1 true PL360087A1 (pl)	2004-09-06
PL200868B1 PL200868B1 (pl)	2009-02-27

Family

ID=11445705

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL360087A PL200868B1 (pl)	2000-08-10	2001-07-27	Sposób wytwarzania 1,14-węglanu 14ß-hydroksy-10-deacetylobakatyny III oraz związki pośrednie

Country Status (22)

Country	Link
US (2)	US6828445B2 (pl)
EP (1)	EP1307436B1 (pl)
JP (1)	JP4907043B2 (pl)
KR (1)	KR100853056B1 (pl)
CN (3)	CN100349882C (pl)
AT (1)	ATE277919T1 (pl)
AU (2)	AU8204001A (pl)
CA (1)	CA2418829C (pl)
CZ (1)	CZ302810B6 (pl)
DE (1)	DE60106057T2 (pl)
DK (1)	DK1307436T3 (pl)
ES (1)	ES2228929T3 (pl)
HU (1)	HU229316B1 (pl)
IL (2)	IL154330A0 (pl)
IT (1)	IT1318678B1 (pl)
NO (1)	NO328124B1 (pl)
PL (1)	PL200868B1 (pl)
PT (1)	PT1307436E (pl)
RU (1)	RU2264394C2 (pl)
SI (1)	SI1307436T1 (pl)
SK (1)	SK286653B6 (pl)
WO (1)	WO2002012215A1 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1320107B1 (it) *	2000-11-28	2003-11-18	Indena Spa	Procedimento per la preparazione di derivati tassanici.
ITMI20012186A1 (it)	2001-10-19	2003-04-19	Indena Spa	Procedimento per la preparazione della 14-beta-idrossi-baccatina iii-1,14-carbonato
ITMI20012185A1 (it) *	2001-10-19	2003-04-19	Indena Spa	Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
ITMI20021921A1 (it)	2002-09-10	2004-03-11	Indena Spa	Funzionalizzazione della posizione 14 dei nuclei tassanici e sintesi di nuovi derivati antitumorali.
US7446126B2 (en) *	2004-10-08	2008-11-04	Indena S.P.A.	Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
ITMI20050614A1 (it) *	2005-04-12	2006-10-13	Indena Spa	Processo per la purificazione della 10-deacetilbaccatina iii dalla 10-deacetil-2-debenzoil-2-pentenoilbaccatina iii
US20080151139A1 (en) *	2006-12-22	2008-06-26	Itt Manufacturing Enterprises, Inc.	Addressable backlight for LCD panel
EP2080764B1 (en)	2008-01-18	2012-08-22	INDENA S.p.A.	Solid forms of ortataxel

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5698712A (en) *	1992-03-06	1997-12-16	Indena S.P.A.	Baccatine III derivatives
IT1254517B (it) *	1992-03-06	1995-09-25	Indena Spa	14-beta idrossi-10-deacetil-baccatina iii, suoi derivati, loro prepazione ed impiego terapeutico
FR2696460B1 (fr) *	1992-10-05	1994-11-25	Rhone Poulenc Rorer Sa	Procédé de préparation de dérivés du taxane.
US5475011A (en) *	1993-03-26	1995-12-12	The Research Foundation Of State University Of New York	Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
FR2721024B1 (fr) *	1994-06-09	1996-07-12	Rhone Poulenc Rorer Sa	Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
IT1275936B1 (it)	1995-03-17	1997-10-24	Indena Spa	Derivati della 10-deacetilbaccatina iii e della 10-deacetil-14b- idrossibaccatina iii loro metodo di preparazione e formulazioni
FR2732341A1 (fr) *	1995-03-27	1996-10-04	Rhone Poulenc Rorer Sa	Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
IT1275435B (it) *	1995-05-19	1997-08-07	Indena Spa	Derivati della 10-desacetil-14beta-idrossibaccatina iii,loro metodo di preparazione e formulazioni che li contengono
KR100345047B1 (ko) *	1998-01-26	2002-07-19	한미약품공업 주식회사	신규한 탁산테르핀계 화합물
IT1308636B1 (it)	1999-03-02	2002-01-09	Indena Spa	Procedimento per la preparazione di tassani da 10-desacetilbaccatinaiii.
ITMI991483A1 (it) *	1999-07-06	2001-01-06	Indena Spa	Derivati tassanici e procedimenti per la loro preparazione
IT1320107B1 (it) *	2000-11-28	2003-11-18	Indena Spa	Procedimento per la preparazione di derivati tassanici.

2000
- 2000-08-10 IT IT2000MI001869A patent/IT1318678B1/it active
2001
- 2001-07-27 CZ CZ20030365A patent/CZ302810B6/cs not_active IP Right Cessation
- 2001-07-27 HU HU0303832A patent/HU229316B1/hu unknown
- 2001-07-27 AU AU8204001A patent/AU8204001A/xx active Pending
- 2001-07-27 WO PCT/EP2001/008730 patent/WO2002012215A1/en not_active Ceased
- 2001-07-27 SK SK159-2003A patent/SK286653B6/sk not_active IP Right Cessation
- 2001-07-27 PT PT01960578T patent/PT1307436E/pt unknown
- 2001-07-27 CN CNB2005100873136A patent/CN100349882C/zh not_active Expired - Lifetime
- 2001-07-27 ES ES01960578T patent/ES2228929T3/es not_active Expired - Lifetime
- 2001-07-27 JP JP2002518192A patent/JP4907043B2/ja not_active Expired - Lifetime
- 2001-07-27 KR KR1020037001790A patent/KR100853056B1/ko not_active Expired - Lifetime
- 2001-07-27 IL IL15433001A patent/IL154330A0/xx active IP Right Grant
- 2001-07-27 US US10/343,991 patent/US6828445B2/en not_active Expired - Lifetime
- 2001-07-27 CA CA002418829A patent/CA2418829C/en not_active Expired - Lifetime
- 2001-07-27 RU RU2003103776/04A patent/RU2264394C2/ru active
- 2001-07-27 DK DK01960578T patent/DK1307436T3/da active
- 2001-07-27 PL PL360087A patent/PL200868B1/pl unknown
- 2001-07-27 CN CNA2007101617507A patent/CN101130528A/zh active Pending
- 2001-07-27 AU AU2001282040A patent/AU2001282040B8/en not_active Expired
- 2001-07-27 SI SI200130208T patent/SI1307436T1/xx unknown
- 2001-07-27 AT AT01960578T patent/ATE277919T1/de active
- 2001-07-27 DE DE60106057T patent/DE60106057T2/de not_active Expired - Lifetime
- 2001-07-27 CN CNB018138675A patent/CN1254470C/zh not_active Expired - Lifetime
- 2001-07-27 EP EP01960578A patent/EP1307436B1/en not_active Expired - Lifetime
2003
- 2003-02-06 IL IL154330A patent/IL154330A/en unknown
- 2003-02-07 NO NO20030609A patent/NO328124B1/no not_active IP Right Cessation
2004
- 2004-10-26 US US10/972,674 patent/US7078538B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
KR100853056B1 (ko)	2008-08-19
ITMI20001869A0 (it)	2000-08-10
US20050113585A1 (en)	2005-05-26
SI1307436T1 (en)	2005-02-28
AU2001282040B2 (en)	2005-09-15
CN1446207A (zh)	2003-10-01
SK286653B6 (sk)	2009-03-05
US20040014998A1 (en)	2004-01-22
ITMI20001869A1 (it)	2002-02-10
HK1055964A1 (en)	2004-01-30
HK1088325A1 (zh)	2006-11-03
US6828445B2 (en)	2004-12-07
AU2001282040B8 (en)	2006-01-19
HUP0303832A3 (en)	2005-02-28
PT1307436E (pt)	2004-11-30
IL154330A (en)	2006-12-31
AU8204001A (en)	2002-02-18
CZ302810B6 (cs)	2011-11-23
EP1307436A1 (en)	2003-05-07
JP4907043B2 (ja)	2012-03-28
JP2004505961A (ja)	2004-02-26
DE60106057D1 (de)	2004-11-04
NO20030609L (no)	2003-02-07
EP1307436B1 (en)	2004-09-29
PL200868B1 (pl)	2009-02-27
WO2002012215A1 (en)	2002-02-14
DK1307436T3 (da)	2005-01-31
CN100349882C (zh)	2007-11-21
NO328124B1 (no)	2009-12-14
US7078538B2 (en)	2006-07-18
DE60106057T2 (de)	2006-02-23
NO20030609D0 (no)	2003-02-07
ES2228929T3 (es)	2005-04-16
HUP0303832A2 (hu)	2004-03-01
KR20030020454A (ko)	2003-03-08
IT1318678B1 (it)	2003-08-27
CA2418829A1 (en)	2002-02-14
IL154330A0 (en)	2003-09-17
CN1254470C (zh)	2006-05-03
SK1592003A3 (en)	2003-07-01
CA2418829C (en)	2009-12-29
CZ2003365A3 (cs)	2003-06-18
HU229316B1 (en)	2013-10-28
CN1736995A (zh)	2006-02-22
CN101130528A (zh)	2008-02-27
RU2264394C2 (ru)	2005-11-20
ATE277919T1 (de)	2004-10-15

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NO20093014L (no)	2002-02-27	Taxanderivater og fremgangsmater ved fremstilling derav
IL154330A0 (en)	2003-09-17	Process for the preparation of baccatin iii derivatives
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GB9909229D0 (en)	1999-06-16	Enantiomers of mercapto lactones and processes for their synthesis
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AU3604601A (en)	2001-09-12	Novel 6-deoxy-6-carbonylthioglucopyranosyl acetimidates, novel intermediates forproduction thereof and processes for production of both