PL361730A1 - Podstawione w pozycji 7 i chlorowcowane w pozycji11 steroidy o działaniu androgenowym - Google Patents

Podstawione w pozycji 7 i chlorowcowane w pozycji11 steroidy o działaniu androgenowym

Info

Publication number: PL361730A1
Authority: PL; Poland
Prior art keywords: androgenic; substituted; halogenated steroids; steroids; halogenated
Prior art date: 2001-01-24

Application number

PL02361730A

Other languages

English (en)

Other versions

PL207582B1 (pl

Inventor

Rolf Bohlmann

Hermann Künzer

Reinhard Nubbemeyer

Dieter Zopf

Original Assignee

Schering Aktiengesellschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-01-24

Filing date

2002-01-24

Publication date

2004-10-04

2002-01-24 Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft

2004-10-04 Publication of PL361730A1 publication Critical patent/PL361730A1/pl

2011-01-31 Publication of PL207582B1 publication Critical patent/PL207582B1/pl

Links

230000001548 androgenic effect Effects 0.000 title 1
150000003431 steroids Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0074—Esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0025—Esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

PL361730A 2001-01-24 2002-01-24 11ß-fluorowcosteroidy, ich otrzymywanie i zastosowanie oraz preparaty farmaceutyczne je zawierające PL207582B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10104327A DE10104327A1 (de)	2001-01-24	2001-01-24	11beta-Halogensteroide, deren Herstellung und Verwendung zur Herstellung von Arzneimitteln sowie 11beta-Halogensteroide enthaltende pharmazeutische Präparate
PCT/EP2002/000722 WO2002059139A1 (en)	2001-01-24	2002-01-24	Androgenic 7-substituted 11-halogen steroids

Publications (2)

Publication Number	Publication Date
PL361730A1 true PL361730A1 (pl)	2004-10-04
PL207582B1 PL207582B1 (pl)	2011-01-31

Family

ID=7672351

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL361730A PL207582B1 (pl)	2001-01-24	2002-01-24	11ß-fluorowcosteroidy, ich otrzymywanie i zastosowanie oraz preparaty farmaceutyczne je zawierające

Country Status (34)

Country	Link
US (1)	US7361645B2 (pl)
EP (1)	EP1353938B1 (pl)
JP (1)	JP4339591B2 (pl)
KR (1)	KR100728088B1 (pl)
CN (1)	CN1234721C (pl)
AR (1)	AR053299A1 (pl)
AT (1)	ATE386045T1 (pl)
AU (1)	AU2002238516B2 (pl)
BG (1)	BG66133B1 (pl)
BR (1)	BR0206653A (pl)
CA (1)	CA2434187C (pl)
CY (1)	CY1110377T1 (pl)
CZ (1)	CZ303553B6 (pl)
DE (2)	DE10104327A1 (pl)
DK (1)	DK1353938T3 (pl)
EA (1)	EA006674B1 (pl)
EE (1)	EE05274B1 (pl)
ES (1)	ES2300431T3 (pl)
HR (1)	HRP20030661B1 (pl)
HU (1)	HUP0303020A3 (pl)
IL (2)	IL156807A0 (pl)
MX (1)	MXPA03006578A (pl)
NO (1)	NO325754B1 (pl)
NZ (1)	NZ527041A (pl)
PE (1)	PE20020848A1 (pl)
PL (1)	PL207582B1 (pl)
PT (1)	PT1353938E (pl)
RS (1)	RS50740B (pl)
SK (1)	SK287444B6 (pl)
TW (1)	TWI333494B (pl)
UA (1)	UA75907C2 (pl)
UY (1)	UY27133A1 (pl)
WO (1)	WO2002059139A1 (pl)
ZA (1)	ZA200306537B (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10234525A1 (de) *	2002-07-25	2004-02-05	Schering Ag	Zusammensetzung, enthaltend ein androgenes 11ß-Halogensteroid und ein Gestagen sowie männliches Kontrazeptivum auf Basis dieser Zusammensetzung
NZ537871A (en)	2002-07-24	2006-10-27	Schering Ag	Microbiological processes for the production of 7 alpha-substituted 11 alpha-hydroxy steroids
DE10233723A1 (de)	2002-07-24	2004-02-12	Schering Ag	Mikrobiologische Verfahren zur Herstellung von 7α-substituierten 11α-Hydroxysteroiden, daraus herstellbare 7α,17α-substituierte 11β-Halogensteroide, deren Herstellungsverfahren und Verwendung sowie pharmazeutische Präparate, die diese Verbindungen enthalten, sowie daraus herstellbare 7α-substituierte Estra-1,3,5(10)-triene
CN1671394A (zh) *	2002-07-25	2005-09-21	舍林股份公司	包含雄激素性11β－卤素甾体和孕激素的组合物以及基于该组合物的雄性避孕药
JO2492B1 (en) *	2003-04-28	2009-10-05	شيرينج ايه جي	A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients
US7879357B2 (en) *	2003-04-28	2011-02-01	Bayer Schering Pharma Ag	Pharmaceutical composition in the form of a hydrogel for transdermal administration of active ingredients
CN106188203B (zh) *	2014-10-08	2017-10-24	常州大学	一种可提高睾酮的收率及大幅减少杂质的合成睾酮方法
TWI530504B (zh) *	2014-12-01	2016-04-21	臺灣永光化學工業股份有限公司	烷基酸睾酮化合物之合成方法
US12410209B2 (en)	2021-06-29	2025-09-09	Board Of Regents, The University Of Texas System	Modified glucocorticoids

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB863661A (en) *	1958-06-06	1961-03-22	Upjohn Co	Improvements in or relating to steroids and the manufacture thereof
CH380118A (de) *	1959-06-17	1964-07-31	Ciba Geigy	Neue Halogenandrostenverbindungen und Verfahren zu deren Herstellung
FR1489519A (fr) *	1965-08-16	1967-07-21	Glaxo Lab Ltd	Procédé de préparation de nouveaux 19-nor-stéroïdes et produits obtenus
GB1159434A (en) *	1965-08-16	1969-07-23	Glaxo Lab Ltd	11beta&;-Fluoro-19-nor-Steroids
US3665021A (en) *	1966-07-29	1972-05-23	Glaxo Lab Ltd	9alpha-unsubstituted-11beta-chloro-l9 nos-steroids
GB1260463A (en) *	1968-01-29	1972-01-19	Glaxo Lab Ltd	11beta-BROMO-19-NOR-STEROIDS
DE2410443A1 (de) *	1974-03-01	1975-09-11	Schering Ag	11beta-fluor-androstene
DE2410442A1 (de) *	1974-03-01	1975-09-11	Schering Ag	Verfahren zur herstellung von 11-fluorandrostenen
DE3214690A1 (de) *	1982-04-16	1983-10-27	Schering AG, 1000 Berlin und 4709 Bergkamen	11ss-chlor-(delta)(pfeil hoch)1(pfeil hoch)(pfeil hoch)5(pfeil hoch)-steroide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
GB8721384D0 (en) *	1987-09-11	1987-10-21	Erba Farmitalia	17-substituted andro-sta-1 4-dien-3-one derivatives
US5342834A (en) *	1989-04-07	1994-08-30	The Population Council, Inc.	Method for androgen supplementation
US6767902B2 (en) *	1997-09-17	2004-07-27	The Population Council, Inc.	Androgen as a male contraceptive and non-contraceptive androgen replacement
US20020012694A1 (en) *	1997-09-17	2002-01-31	Alfred J. Moo-Young	Transdermal administration of ment
US5952319A (en) *	1997-11-26	1999-09-14	Research Triangle Institute	Androgenic steroid compounds and a method of making and using the same
DE60000826T2 (de) *	1999-03-08	2003-04-10	Akzo Nobel N.V., Arnheim/Arnhem	14.beta.,17-alpha-hydroxymethylandrostan derivate als androgene
ES2204613T3 (es) *	1999-04-06	2004-05-01	Akzo Nobel N.V.	Androgenos 7-alfa alquilo oralmente activos.
DE19959696A1 (de) *	1999-12-08	2001-06-21	Jenapharm Gmbh	Ungesättigte 14,15-Cyclopropano-Androstane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen

2001
- 2001-01-24 DE DE10104327A patent/DE10104327A1/de not_active Ceased
2002
- 2002-01-24 US US10/467,352 patent/US7361645B2/en not_active Expired - Fee Related
- 2002-01-24 DE DE60224982T patent/DE60224982T2/de not_active Expired - Lifetime
- 2002-01-24 BR BR0206653-0A patent/BR0206653A/pt not_active IP Right Cessation
- 2002-01-24 RS YUP-594/03A patent/RS50740B/sr unknown
- 2002-01-24 CN CNB028040686A patent/CN1234721C/zh not_active Expired - Fee Related
- 2002-01-24 EP EP02704667A patent/EP1353938B1/en not_active Expired - Lifetime
- 2002-01-24 IL IL15680702A patent/IL156807A0/xx active IP Right Grant
- 2002-01-24 AR ARP020100238A patent/AR053299A1/es active IP Right Grant
- 2002-01-24 SK SK954-2003A patent/SK287444B6/sk not_active IP Right Cessation
- 2002-01-24 AT AT02704667T patent/ATE386045T1/de active
- 2002-01-24 TW TW091101142A patent/TWI333494B/zh not_active IP Right Cessation
- 2002-01-24 EE EEP200300346A patent/EE05274B1/xx not_active IP Right Cessation
- 2002-01-24 KR KR1020037009732A patent/KR100728088B1/ko not_active Expired - Fee Related
- 2002-01-24 PL PL361730A patent/PL207582B1/pl not_active IP Right Cessation
- 2002-01-24 ES ES02704667T patent/ES2300431T3/es not_active Expired - Lifetime
- 2002-01-24 UA UA2003087912A patent/UA75907C2/uk unknown
- 2002-01-24 NZ NZ527041A patent/NZ527041A/en not_active IP Right Cessation
- 2002-01-24 PE PE2002000053A patent/PE20020848A1/es not_active Application Discontinuation
- 2002-01-24 AU AU2002238516A patent/AU2002238516B2/en not_active Ceased
- 2002-01-24 PT PT02704667T patent/PT1353938E/pt unknown
- 2002-01-24 JP JP2002559441A patent/JP4339591B2/ja not_active Expired - Fee Related
- 2002-01-24 HU HU0303020A patent/HUP0303020A3/hu unknown
- 2002-01-24 UY UY27133A patent/UY27133A1/es not_active Application Discontinuation
- 2002-01-24 CZ CZ20032006A patent/CZ303553B6/cs not_active IP Right Cessation
- 2002-01-24 HR HR20030661A patent/HRP20030661B1/xx not_active IP Right Cessation
- 2002-01-24 DK DK02704667T patent/DK1353938T3/da active
- 2002-01-24 EA EA200300756A patent/EA006674B1/ru not_active IP Right Cessation
- 2002-01-24 MX MXPA03006578A patent/MXPA03006578A/es active IP Right Grant
- 2002-01-24 CA CA002434187A patent/CA2434187C/en not_active Expired - Fee Related
- 2002-01-24 WO PCT/EP2002/000722 patent/WO2002059139A1/en not_active Ceased
2003
- 2003-07-07 IL IL156807A patent/IL156807A/en not_active IP Right Cessation
- 2003-07-23 NO NO20033321A patent/NO325754B1/no not_active IP Right Cessation
- 2003-07-23 BG BG108023A patent/BG66133B1/bg unknown
- 2003-08-21 ZA ZA200306537A patent/ZA200306537B/en unknown
2008
- 2008-05-13 CY CY20081100508T patent/CY1110377T1/el unknown

Also Published As

Publication number	Publication date
ZA200306537B (en)	2004-09-08
CN1487950A (zh)	2004-04-07
EP1353938A1 (en)	2003-10-22
BG66133B1 (bg)	2011-06-30
JP2004517153A (ja)	2004-06-10
NO20033321D0 (no)	2003-07-23
NO20033321L (no)	2003-09-24
PE20020848A1 (es)	2002-10-26
US7361645B2 (en)	2008-04-22
WO2002059139A1 (en)	2002-08-01
EE200300346A (et)	2003-12-15
CY1110377T1 (el)	2015-04-29
PL207582B1 (pl)	2011-01-31
JP4339591B2 (ja)	2009-10-07
HK1064678A1 (en)	2005-02-04
SK9542003A3 (en)	2003-12-02
PT1353938E (pt)	2008-04-29
AR053299A1 (es)	2007-05-02
AU2002238516B2 (en)	2007-08-23
EA006674B1 (ru)	2006-02-24
DE10104327A1 (de)	2002-07-25
KR100728088B1 (ko)	2007-06-14
IL156807A (en)	2008-08-07
CA2434187A1 (en)	2002-08-01
ES2300431T3 (es)	2008-06-16
HRP20030661A2 (en)	2005-06-30
HRP20030661B1 (en)	2011-10-31
US20050075322A1 (en)	2005-04-07
TWI333494B (en)	2010-11-21
CA2434187C (en)	2009-06-16
DK1353938T3 (da)	2008-05-26
DE60224982T2 (de)	2009-04-09
BG108023A (bg)	2004-02-27
CZ303553B6 (cs)	2012-12-05
NZ527041A (en)	2005-02-25
CZ20032006A3 (cs)	2004-01-14
SK287444B6 (sk)	2010-09-07
BR0206653A (pt)	2004-02-03
CN1234721C (zh)	2006-01-04
KR20030081391A (ko)	2003-10-17
ATE386045T1 (de)	2008-03-15
UA75907C2 (en)	2006-06-15
HUP0303020A3 (en)	2012-03-28
HUP0303020A2 (hu)	2003-12-29
NO325754B1 (no)	2008-07-14
EP1353938B1 (en)	2008-02-13
YU59403A (sh)	2006-08-17
UY27133A1 (es)	2002-07-31
IL156807A0 (en)	2004-02-08
RS50740B (sr)	2010-08-31
DE60224982D1 (de)	2008-03-27
MXPA03006578A (es)	2003-09-22
EE05274B1 (et)	2010-02-15
EA200300756A1 (ru)	2004-02-26

Legal Events

Date	Code	Title	Description
2015-04-30	LAPS	Decisions on the lapse of the protection rights	Effective date: 20140124

Publication	Publication Date	Title
HUP0400646A3 (en)	2012-08-28	Steroid hormone-compositions and processes for their preparation
IL144916A0 (en)	2002-06-30	Immunomodulatory steroids, in particular the hemihydrate of 16-alpha-bromoepiandrosterone
IL156807A0 (en)	2004-02-08	Androgenic 7-substituted 11-halogen steroids
ZA200507351B (en)	2008-04-30	Steroid spirolactonization
IL162495A0 (en)	2005-11-20	Cone
GB2389377B (en)	2004-11-24	Panel
GB2378207B (en)	2005-03-09	Panel end fitting
GB0126009D0 (en)	2001-12-19	Panel
GB0213065D0 (en)	2002-07-17	An insulatd panel
GB0128573D0 (en)	2002-01-23	Bright surrounds
GB0118715D0 (en)	2001-09-26	Panel end fitting
EP1433906A4 (en)	2005-01-12	SIGN
GB0100301D0 (en)	2001-02-14	Estrogen receptor
GB0100298D0 (en)	2001-02-14	Estrogen receptor
GB0100299D0 (en)	2001-02-14	Estrogen receptor
GB0109206D0 (en)	2001-05-30	Panel sleeve
GB0003525D0 (en)	2000-04-05	Cytoprotective steroids (I)
CA91990S (en)	2001-03-30	Bus
GB0120721D0 (en)	2001-10-17	Cone gearing
GB0100302D0 (en)	2001-02-14	Estrogen receptors
TW462455U (en)	2001-11-01	Fast fitting
TW456488U (en)	2001-09-21	Improved structure for fast pneumatic fitting
AU2492302A (en)	2002-06-24	Methylene steroids as novel androgens
GB0110212D0 (en)	2001-06-20	Circular tail-wing aircraft
TW517810U (en)	2003-01-11	Fast fitting for tube