PL362982A1 - Związki pochodne benzotiofenu, sposoby ich wytwarzania i ich zastosowanie - Google Patents

Związki pochodne benzotiofenu, sposoby ich wytwarzania i ich zastosowanie

Info

Publication number
PL362982A1
PL362982A1 PL01362982A PL36298201A PL362982A1 PL 362982 A1 PL362982 A1 PL 362982A1 PL 01362982 A PL01362982 A PL 01362982A PL 36298201 A PL36298201 A PL 36298201A PL 362982 A1 PL362982 A1 PL 362982A1
Authority
PL
Poland
Prior art keywords
preparation
derivative compounds
benzothiophene derivative
benzothiophene
compounds
Prior art date
Application number
PL01362982A
Other languages
English (en)
Inventor
Castillo Nieto Juan Carlos Del
Aldaz Berta Esperanza Lasheras
Vega Antonio Monge
Mancini Marisabel Mourelle
Rio Zambrana Joaquin Del
Original Assignee
Laboratorios Vita S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Vita S.A. filed Critical Laboratorios Vita S.A.
Publication of PL362982A1 publication Critical patent/PL362982A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Thin Film Transistor (AREA)
PL01362982A 2000-11-29 2001-11-19 Związki pochodne benzotiofenu, sposoby ich wytwarzania i ich zastosowanie PL362982A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200002914A ES2188344B1 (es) 2000-11-29 2000-11-29 Compuestos derivados de benzotiofeno, su procedimiento de obtencion y utilizacion de los mismos.
PCT/IB2001/002211 WO2002044170A2 (en) 2000-11-29 2001-11-19 Benzothiophene derivative compounds, process of preparation and use thereof

Publications (1)

Publication Number Publication Date
PL362982A1 true PL362982A1 (pl) 2004-11-02

Family

ID=8495887

Family Applications (1)

Application Number Title Priority Date Filing Date
PL01362982A PL362982A1 (pl) 2000-11-29 2001-11-19 Związki pochodne benzotiofenu, sposoby ich wytwarzania i ich zastosowanie

Country Status (35)

Country Link
US (1) US20040034219A1 (pl)
EP (1) EP1337528B1 (pl)
JP (1) JP2004514719A (pl)
KR (1) KR20030066689A (pl)
CN (1) CN1478088A (pl)
AP (1) AP2003002801A0 (pl)
AR (1) AR034009A1 (pl)
AT (1) ATE272634T1 (pl)
AU (1) AU2002215157A1 (pl)
BG (1) BG107851A (pl)
BR (1) BR0115708A (pl)
CA (1) CA2429892A1 (pl)
CZ (1) CZ20031398A3 (pl)
DE (1) DE60104717T2 (pl)
EA (1) EA200300519A1 (pl)
EE (1) EE200300245A (pl)
ES (2) ES2188344B1 (pl)
GE (1) GEP20043366B (pl)
HR (1) HRP20030407A2 (pl)
HU (1) HUP0303568A3 (pl)
IL (1) IL155966A0 (pl)
IS (1) IS6824A (pl)
MA (1) MA26963A1 (pl)
MX (1) MXPA03004875A (pl)
NO (1) NO20032332D0 (pl)
NZ (1) NZ525950A (pl)
OA (1) OA12536A (pl)
PE (1) PE20020692A1 (pl)
PL (1) PL362982A1 (pl)
PT (1) PT1337528E (pl)
SI (1) SI1337528T1 (pl)
SK (1) SK6202003A3 (pl)
TR (1) TR200402779T4 (pl)
WO (1) WO2002044170A2 (pl)
ZA (1) ZA200303858B (pl)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1408976T5 (da) * 2001-07-20 2011-01-10 Psychogenics Inc Behandling af ADHD (Attention deficit hyperactivity disorder)
ES2386828T3 (es) 2002-03-27 2012-08-31 Glaxo Group Limited Derivados de quinolina y su uso como ligandos 5-HT6
JP2006516977A (ja) 2003-01-13 2006-07-13 ダイノゲン ファーマシューティカルズ，インコーポレイテッド 悪心、嘔吐、レッチング、またはそれらの任意の組み合わせの治療方法
US7276603B2 (en) 2003-05-02 2007-10-02 Wyeth Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use
US8754238B2 (en) 2003-07-22 2014-06-17 Arena Pharmaceuticals, Inc. Diaryl and arylheteroaryl urea derivatives as modulators of the 5-HT2A serotonin receptor useful for the prophylaxis and treatment of disorders related thereto
DE102004023507A1 (de) * 2004-05-10 2005-12-01 Grünenthal GmbH Substituierte Cyclohexylessigsäure-Derivate
DE102004023632A1 (de) * 2004-05-10 2005-12-08 Grünenthal GmbH Substituierte Cyclohexylcarbonsäure-Derivate
DE102004023522A1 (de) * 2004-05-10 2005-12-01 Grünenthal GmbH Substituierte Cyclohexyl-1,4-diamin-Derivate
DE102004023508A1 (de) * 2004-05-10 2005-12-08 Grünenthal GmbH Säurederivate substituierter Cyclohexyl-1,4-diamine
DE102004023635A1 (de) * 2004-05-10 2006-04-13 Grünenthal GmbH Heteroarylsubstituierte Cyclohexyl-1,4-diamin-Derivate
DE102004023506A1 (de) * 2004-05-10 2005-12-01 Grünenthal GmbH Kettenverlängerte substituierte Cyclohexyl-1,4-diamin-Derivate
DE102004023501A1 (de) * 2004-05-10 2005-12-01 Grünenthal GmbH Oxosubstituierte Cyclohexyl-1,4-diamin-Derivate
US7881267B2 (en) * 2004-06-04 2011-02-01 Hewlett-Packard Development Company, L.P. Portable computing device for wireless communications and method of operation
DE102004063797A1 (de) * 2004-12-30 2006-07-13 Schwarz Pharma Ag Sauerstoffhaltige annelierte Phenylpiperazin- und Phenyldiazepancarboxamide
US7582634B2 (en) 2005-02-18 2009-09-01 Wyeth 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
US7534796B2 (en) 2005-02-18 2009-05-19 Wyeth Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor
US7538113B2 (en) 2005-02-18 2009-05-26 Wyeth 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
US7531542B2 (en) 2005-05-18 2009-05-12 Wyeth Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor
US7582636B2 (en) 2005-05-26 2009-09-01 Wyeth Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor
US9084742B2 (en) 2007-12-12 2015-07-21 Axovant Sciences Ltd. Combinations comprising 3-phenylsulfonyl-8-piperazinyl-1yl-Quinoline
US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
CN101619056B (zh) * 2008-07-02 2013-07-17 石药集团中奇制药技术（石家庄）有限公司 苯并噻吩烷醇哌嗪衍生物及其作为抗抑郁症药物的应用
WO2010062321A1 (en) 2008-10-28 2010-06-03 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto
WO2015014256A1 (en) 2013-07-29 2015-02-05 Sunshine Lake Pharma Co., Ltd. Substituted heteroaryl compounds and methods of use thereof
CN106243088B (zh) 2015-06-03 2019-01-04 广东东阳光药业有限公司 取代的哌嗪化合物及其使用方法和用途
RU2017145976A (ru) 2015-06-12 2019-07-15 Аксовант Сайенсиз Гмбх Производные диарил- и арилгетероарилмочевины, применимые для профилактики и лечения нарушения поведения во время REM-фазы сна
TW201720439A (zh) 2015-07-15 2017-06-16 Axovant Sciences Gmbh 用於預防及治療與神經退化性疾病相關的幻覺之作為５－ｈｔ２ａ血清素受體的二芳基及芳基雜芳基脲衍生物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487773A (en) * 1981-03-16 1984-12-11 Mead Johnson & Company 1,2,4-Triazol-3-one antidepressants
ZA929008B (en) * 1991-12-13 1993-05-21 Bristol Myers Squibb Co Piperazinyl- and piperidinyl-cyclohexanols.
FR2692264B1 (fr) * 1992-06-12 1994-08-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
US5658909A (en) * 1994-11-17 1997-08-19 Molecular Geriatrics Corporation Certain substituted 1-aryl-3-piperazin-1'-yl propanones to treat Alzheimer's Disease
US5693804A (en) * 1994-11-17 1997-12-02 Molecular Geriatrics Corporation Substituted 1-aryl-3-piperazin-1'-yl propanones
ES2128266B1 (es) * 1997-07-08 2000-01-16 Vita Invest Sa Compuestos derivados de tiofeno y benzotiofeno y utilizacion y composicion correspondientes.

Also Published As

Publication number Publication date
EE200300245A (et) 2003-08-15
TR200402779T4 (tr) 2004-11-22
ES2188344B1 (es) 2004-09-16
US20040034219A1 (en) 2004-02-19
WO2002044170A3 (en) 2002-09-06
HRP20030407A2 (en) 2004-08-31
NO20032332L (no) 2003-05-22
AP2003002801A0 (en) 2003-06-30
IS6824A (is) 2003-05-22
EP1337528B1 (en) 2004-08-04
MA26963A1 (fr) 2004-12-20
PE20020692A1 (es) 2002-09-02
ATE272634T1 (de) 2004-08-15
MXPA03004875A (es) 2005-02-14
IL155966A0 (en) 2003-12-23
ES2225623T3 (es) 2005-03-16
HUP0303568A3 (en) 2005-02-28
HUP0303568A2 (hu) 2004-03-01
NZ525950A (en) 2004-11-26
NO20032332D0 (no) 2003-05-22
CZ20031398A3 (cs) 2004-01-14
AR034009A1 (es) 2004-01-21
ZA200303858B (en) 2004-05-19
WO2002044170A2 (en) 2002-06-06
KR20030066689A (ko) 2003-08-09
JP2004514719A (ja) 2004-05-20
SK6202003A3 (en) 2004-05-04
EP1337528A2 (en) 2003-08-27
OA12536A (en) 2006-06-05
CN1478088A (zh) 2004-02-25
DE60104717D1 (de) 2004-09-09
SI1337528T1 (en) 2005-02-28
PT1337528E (pt) 2004-11-30
ES2188344A1 (es) 2003-06-16
CA2429892A1 (en) 2002-06-06
DE60104717T2 (de) 2006-04-06
GEP20043366B (en) 2004-04-13
AU2002215157A1 (en) 2002-06-11
BR0115708A (pt) 2004-02-03
EA200300519A1 (ru) 2003-12-25
BG107851A (bg) 2004-06-30

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