PL3630111T3 - Związki i sposoby leczenia zakażeń bakteryjnych - Google Patents

Związki i sposoby leczenia zakażeń bakteryjnych

Info

Publication number
PL3630111T3
PL3630111T3 PL18726702T PL18726702T PL3630111T3 PL 3630111 T3 PL3630111 T3 PL 3630111T3 PL 18726702 T PL18726702 T PL 18726702T PL 18726702 T PL18726702 T PL 18726702T PL 3630111 T3 PL3630111 T3 PL 3630111T3
Authority
PL
Poland
Prior art keywords
compounds
methods
bacterial infections
treating bacterial
treating
Prior art date
Application number
PL18726702T
Other languages
English (en)
Inventor
Janelle Comita-Prevoir
Thomas Francois Durand-Reville
Satenig GULER
Jan Romero
Mark Sylvester
Ruben Tommasi
Camilo VELEZ-VEGA
Xiaoyun Wu
Jing Zhang
Original Assignee
Entasis Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Entasis Therapeutics, Inc. filed Critical Entasis Therapeutics, Inc.
Publication of PL3630111T3 publication Critical patent/PL3630111T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL18726702T 2017-05-08 2018-05-08 Związki i sposoby leczenia zakażeń bakteryjnych PL3630111T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762502867P 2017-05-08 2017-05-08
PCT/US2018/031593 WO2018208769A1 (en) 2017-05-08 2018-05-08 Compounds and methods for treating bacterial infections
EP18726702.6A EP3630111B1 (en) 2017-05-08 2018-05-08 Compounds and methods for treating bacterial infections

Publications (1)

Publication Number Publication Date
PL3630111T3 true PL3630111T3 (pl) 2022-05-23

Family

ID=62223332

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18726702T PL3630111T3 (pl) 2017-05-08 2018-05-08 Związki i sposoby leczenia zakażeń bakteryjnych

Country Status (27)

Country Link
US (1) US11046694B2 (pl)
EP (1) EP3630111B1 (pl)
JP (1) JP7058322B2 (pl)
KR (1) KR102611447B1 (pl)
CN (1) CN110709081B (pl)
AU (1) AU2018266640B2 (pl)
CY (1) CY1125340T1 (pl)
DK (1) DK3630111T3 (pl)
EA (1) EA038393B1 (pl)
ES (1) ES2907858T3 (pl)
HR (1) HRP20220231T1 (pl)
HU (1) HUE057592T2 (pl)
IL (1) IL270380B (pl)
LT (1) LT3630111T (pl)
MA (1) MA48743A (pl)
MX (1) MX385203B (pl)
MY (1) MY201377A (pl)
NZ (1) NZ758200A (pl)
PE (1) PE20200333A1 (pl)
PH (1) PH12019502509A1 (pl)
PL (1) PL3630111T3 (pl)
PT (1) PT3630111T (pl)
SG (1) SG11201909443YA (pl)
SI (1) SI3630111T1 (pl)
SM (1) SMT202200110T1 (pl)
TW (1) TWI791018B (pl)
WO (1) WO2018208769A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11905286B2 (en) 2018-08-09 2024-02-20 Antabio Sas Diazabicyclooctanones as inhibitors of serine beta-lactamases
KR102790878B1 (ko) 2018-08-09 2025-04-02 앤타바이오 에스에이에스 세린 베타-락타마제의 억제제로서 다이아자바이사이클로옥타논
CN111675641B (zh) * 2020-06-04 2023-09-08 宁夏农林科学院农业资源与环境研究所（宁夏土壤与植物营养重点实验室） 单环β-内酰胺类化合物、单环内酰胺类化合物盐及其制备方法
EP4146651B1 (en) 2021-05-07 2026-03-04 Ningxia Academy of Agriculture and Forestry Sciences Sulfonylamidine substituted compounds and their use as beta-lactamase inhibitors
US11814385B2 (en) 2021-06-25 2023-11-14 University Of South Florida Small molecule inhibitors targeting Clostridioides difficile sporulation
WO2025064681A1 (en) * 2023-09-19 2025-03-27 Entasis Therapeutics Inc. Compounds and methods for treating bacterial infections

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NZ274915A (en) 1993-12-29 1997-11-24 Pfizer N-(hetero)aryl methyl diazabicycloalkane derivatives
FR2812635B1 (fr) 2000-08-01 2002-10-11 Aventis Pharma Sa Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens
FR2825705B1 (fr) 2001-06-08 2005-05-20 Aventis Pharma Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens
FR2835186B1 (fr) 2002-01-28 2006-10-20 Aventis Pharma Sa Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases
FR2848210B1 (fr) 2002-12-06 2007-10-19 Aventis Pharma Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens et inhibiteurs de beta-lactamases
US7439253B2 (en) * 2002-12-06 2008-10-21 Novexel Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
US7507727B2 (en) * 2003-04-07 2009-03-24 Cylene Pharmaceuticals, Inc. Substituted quinobenzoxazine analogs and methods of using thereof
FR2914923B1 (fr) 2007-04-12 2013-06-14 Novexel Nouveaux composes heterocycliques azotes,leur preparation et leur utilisation comme medicaments antibacteriens.
MY162532A (en) 2008-01-18 2017-06-15 Merck Sharp & Dohme Beta-lactamase inhibitors
FR2930553B1 (fr) 2008-04-29 2010-05-21 Novexel Composes azabicycliques, leur preparation et leur utilisation comme medicaments, notamment inhibiteurs de beta-lactamases
EP3260551A1 (en) 2008-06-19 2017-12-27 Astra Zeneca Holding France Use of (1r,2s,5r) 1,6-diazabicyclo [3.2.1] octane-2-carboxamide, 7-oxo-6-(sulfooxy)-, monosodium salt as a diagnostic reagent for detecting serine beta-lactamases
FR2936798B1 (fr) 2008-10-03 2012-09-28 Novexel Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens.
FR2937034B1 (fr) * 2008-10-10 2012-11-23 Novexel Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens
FR2936951B1 (fr) 2008-10-10 2010-12-03 Novexel Nouvelles combinaisons de composes heterocycliques azotes antibacteriens avec d'autres composes antibacteriens et leur utilisation comme medicaments
FR2951171A1 (fr) 2009-10-09 2011-04-15 Novexel Nouveau sel de sodium d'un compose azabicyclique sous forme enantiomere cristallisee et nouvelles formes polymorphes et pseudopolymorphes ainsi que leur preparation
MX338610B (es) 2011-07-26 2016-04-25 Wockhardt Ltd Composiciones farmaceuticas que comprenden sulbactam e inhibidor de beta-lactamasa.
MX362683B (es) 2011-07-26 2019-01-31 Wockhardt Ltd Composiciones farmacéuticas que comprenden antibiótico de beta-lactama, sulbactama e inhibidor de beta-lactamasa.
KR101512738B1 (ko) 2011-08-27 2015-04-17 욱크하르트 리미티드 1,6-디아자-비시클로[3,2,1]옥탄-7-온 유도체 및 세균 감염 치료에서의 그 유도체의 용도
KR101618424B1 (ko) 2011-08-30 2016-05-04 욱크하르트 리미티드 1,6-디아자비시클로[3,2,1]옥탄-7-온 유도체 및 세균 감염 치료에서의 그 유도체의 용도
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CA2889793C (en) 2012-09-03 2017-09-26 Wockhardt Limited Antibacterial compositions
CN104994860A (zh) 2013-02-06 2015-10-21 阿斯利康(瑞典)有限公司 用于治疗医院性肺炎的组合疗法
WO2014141132A1 (en) 2013-03-14 2014-09-18 Naeja Pharmaceutical Inc. NEW HETEROCYCLIC COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS AND β-LACTAMASE INHIBITORS
BR112017010132B1 (pt) 2014-11-17 2023-02-14 Entasis Therapeutics Limited Combinações e seus usos no tratamento de infecções bacterianas resistentes
CA3036557A1 (en) 2016-09-16 2018-03-22 Entasis Therapeutics Limited Beta-lactamase inhibitor compounds

Also Published As

Publication number Publication date
MA48743A (fr) 2020-04-08
US11046694B2 (en) 2021-06-29
CA3059773A1 (en) 2018-11-15
WO2018208769A1 (en) 2018-11-15
KR20200005586A (ko) 2020-01-15
JP7058322B2 (ja) 2022-04-21
NZ758200A (en) 2025-12-19
EA201992370A1 (ru) 2020-03-10
TWI791018B (zh) 2023-02-01
TW201843152A (zh) 2018-12-16
AU2018266640B2 (en) 2022-03-03
CN110709081A (zh) 2020-01-17
HRP20220231T1 (hr) 2022-04-29
MY201377A (en) 2024-02-21
EA038393B1 (ru) 2021-08-20
DK3630111T3 (en) 2022-03-14
KR102611447B1 (ko) 2023-12-06
AU2018266640A1 (en) 2019-11-07
SMT202200110T1 (it) 2022-05-12
BR112019023130A2 (pt) 2020-05-26
SI3630111T1 (sl) 2022-05-31
PT3630111T (pt) 2022-03-01
JP2020519687A (ja) 2020-07-02
CN110709081B (zh) 2023-09-22
LT3630111T (lt) 2022-03-10
US20200165251A1 (en) 2020-05-28
IL270380B (en) 2022-06-01
HUE057592T2 (hu) 2022-05-28
CY1125340T1 (el) 2024-02-16
EP3630111B1 (en) 2021-11-24
MX385203B (es) 2025-03-14
ES2907858T3 (es) 2022-04-26
SG11201909443YA (en) 2019-11-28
PH12019502509A1 (en) 2020-07-13
PE20200333A1 (es) 2020-02-14
MX2019013291A (es) 2020-01-15
EP3630111A1 (en) 2020-04-08

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