PL363264A1 - Pochodne izoksazoliny jako środki przeciwdepresyjne - Google Patents

Pochodne izoksazoliny jako środki przeciwdepresyjne

Info

Publication number: PL363264A1
Authority: PL; Poland
Prior art keywords: depressants; isoxazoline derivatives; isoxazoline; derivatives
Prior art date: 2001-02-21

Application number

PL02363264A

Other languages

English (en)

Other versions

PL208593B1 (pl

Inventor

Jose Ignacio Andres-Gil

Francisco Javier Fernandez-Gadea

Manuel Jesus Alcazar-Vaca

Jose Maria Cid-Nunez

Joaquin Pastor-Fernandez

Antonius Adrianus Hendrikus Petrus Megens

Godelieve Irma Christine Maria Heylen

Xavier Jean Michel Langlois

Margaretha Henrica Maria Bakker

Thomas Horst Wolfgang Steckler

Original Assignee

Janssen Pharmaceutica N.V.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-21

Filing date

2002-02-13

Publication date

2004-11-15

2002-02-13 Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.

2004-11-15 Publication of PL363264A1 publication Critical patent/PL363264A1/pl

2011-05-31 Publication of PL208593B1 publication Critical patent/PL208593B1/pl

Links

230000001430 anti-depressive effect Effects 0.000 title 1
239000000935 antidepressant agent Substances 0.000 title 1
229940005513 antidepressants Drugs 0.000 title 1
150000002547 isoxazolines Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Child & Adolescent Psychology (AREA)
Hematology (AREA)
Obesity (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

PL363264A 2001-02-21 2002-02-13 Pochodne izoksazoliny, kompozycja farmaceutyczna je zawierająca oraz ich zastosowanie PL208593B1 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP01200611		2001-02-21
EP01201264		2001-04-05
PCT/EP2002/001567 WO2002066484A1 (en)	2001-02-21	2002-02-13	Isoxazoline derivatives as anti-depressants

Publications (2)

Publication Number	Publication Date
PL363264A1 true PL363264A1 (pl)	2004-11-15
PL208593B1 PL208593B1 (pl)	2011-05-31

Family

ID=26076836

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL363264A PL208593B1 (pl)	2001-02-21	2002-02-13	Pochodne izoksazoliny, kompozycja farmaceutyczna je zawierająca oraz ich zastosowanie

Country Status (32)

Country	Link
US (1)	US7169786B2 (pl)
EP (1)	EP1368358B1 (pl)
JP (1)	JP3953424B2 (pl)
KR (1)	KR100848898B1 (pl)
CN (1)	CN100400540C (pl)
AR (1)	AR035685A1 (pl)
AT (1)	ATE337322T1 (pl)
AU (1)	AU2002244717B2 (pl)
BG (1)	BG107984A (pl)
BR (1)	BR0207433A (pl)
CA (1)	CA2437505C (pl)
CY (1)	CY1106448T1 (pl)
CZ (1)	CZ20032515A3 (pl)
DE (1)	DE60214138T2 (pl)
DK (1)	DK1368358T3 (pl)
EA (1)	EA006747B1 (pl)
EE (1)	EE200300398A (pl)
EG (1)	EG23929A (pl)
ES (1)	ES2271230T3 (pl)
HR (1)	HRP20030647A2 (pl)
HU (1)	HUP0303270A3 (pl)
IL (2)	IL157470A0 (pl)
MX (1)	MXPA03007432A (pl)
MY (1)	MY137836A (pl)
NO (1)	NO20033700L (pl)
NZ (1)	NZ526741A (pl)
PL (1)	PL208593B1 (pl)
PT (1)	PT1368358E (pl)
SI (1)	SI1368358T1 (pl)
SK (1)	SK11612003A3 (pl)
TW (1)	TWI257392B (pl)
WO (1)	WO2002066484A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0203299D0 (en) *	2002-02-12	2002-03-27	Glaxo Group Ltd	Novel compounds
JP4580653B2 (ja) *	2002-04-02	2010-11-17	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	置換されたアミノイソオキサゾリン誘導体および抗鬱薬としてのそれらの使用
TW200409777A (en) *	2002-08-12	2004-06-16	Janssen Pharmaceutica Nv	C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants
CA2494557C (en)	2002-08-15	2011-10-18	Janssen Pharmaceutica N.V.	Fused heterocyclic isoxazoline derivatives and their use as anti-depressants
CA2495058C (en) *	2002-08-21	2012-01-03	Janssen Pharmaceutica N.V.	C6- and c9-substituted isoxazoline derivatives and their use as anti-depressants
US8044206B2 (en)	2003-03-07	2011-10-25	Astellas Pharma Inc.	Nitrogen—containing heterocyclic derivatives having 2,6-disubstituted styryl
EP1905774B1 (en) *	2003-09-17	2013-02-20	Janssen Pharmaceutica N.V.	Fused heterocyclic compounds as serotonin receptor modulators
JP5069907B2 (ja) *	2003-09-17	2012-11-07	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	縮合複素環式化合物
ATE443707T1 (de) *	2004-11-26	2009-10-15	Janssen Pharmaceutica Nv	Isoxazolin-indol-derivate mit verbesserter antipsychotischer und anxiolytischer aktivität
RU2470937C2 (ru)	2007-03-09	2012-12-27	Санофи-Авентис	Получение и применение замещенных дигидро- и тетрагидрооксазолопиримидинонов
KR20100038189A (ko) *	2007-06-08	2010-04-13	헬리콘 테라퓨틱스 인코퍼레이티드	치료적 피라졸로퀴놀린 우레아 유도체
EP2236511A4 (en)	2007-12-21	2011-04-13	Alla Chem Llc	LIGANDS OF ALPHA ADRENOCEPTORS AND OF DOPAMINE, HISTAMIN, IMIDAZOLIN AND SEROTONIN RECEPTORS AND THEIR APPLICATION THEREOF
AR078171A1 (es)	2009-09-15	2011-10-19	Sanofi Aventis	Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE68906340T2 (de) *	1988-09-19	1993-08-12	Akzo Nv	Tetrahydronaphthalin und indan-derivate.
US5880121A (en) *	1996-01-05	1999-03-09	Hoechst Marion Roussel Inc.	4,5-dihydronaphth (1,2-c) isoxazoles and derivatives thereof
DK0892804T3 (da) *	1996-04-12	2002-12-02	Janssen Pharmaceutica Nv	Isoxazolidin derivater
HUP9602763A3 (en) *	1996-10-09	1999-05-28	Egyt Gyogyszervegyeszeti Gyar	3-phenyl isoxazole derivatives, process for producing them and pharmaceutical compositions containing the same
JP2002527438A (ja) *	1998-10-09	2002-08-27	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	４，５−ジヒドロ−イソオキサゾール誘導体及びそれらの製薬学的使用

2002
- 2002-02-13 SI SI200230433T patent/SI1368358T1/sl unknown
- 2002-02-13 KR KR1020037008328A patent/KR100848898B1/ko not_active Expired - Fee Related
- 2002-02-13 EA EA200300915A patent/EA006747B1/ru not_active IP Right Cessation
- 2002-02-13 PT PT02712909T patent/PT1368358E/pt unknown
- 2002-02-13 HU HU0303270A patent/HUP0303270A3/hu unknown
- 2002-02-13 CA CA2437505A patent/CA2437505C/en not_active Expired - Lifetime
- 2002-02-13 CZ CZ20032515A patent/CZ20032515A3/cs unknown
- 2002-02-13 EP EP02712909A patent/EP1368358B1/en not_active Expired - Lifetime
- 2002-02-13 NZ NZ526741A patent/NZ526741A/en unknown
- 2002-02-13 US US10/468,555 patent/US7169786B2/en not_active Expired - Lifetime
- 2002-02-13 CN CNB028052439A patent/CN100400540C/zh not_active Expired - Fee Related
- 2002-02-13 MX MXPA03007432A patent/MXPA03007432A/es active IP Right Grant
- 2002-02-13 PL PL363264A patent/PL208593B1/pl unknown
- 2002-02-13 DK DK02712909T patent/DK1368358T3/da active
- 2002-02-13 AU AU2002244717A patent/AU2002244717B2/en not_active Expired
- 2002-02-13 ES ES02712909T patent/ES2271230T3/es not_active Expired - Lifetime
- 2002-02-13 AT AT02712909T patent/ATE337322T1/de not_active IP Right Cessation
- 2002-02-13 EE EEP200300398A patent/EE200300398A/xx unknown
- 2002-02-13 BR BR0207433-8A patent/BR0207433A/pt not_active IP Right Cessation
- 2002-02-13 IL IL15747002A patent/IL157470A0/xx unknown
- 2002-02-13 SK SK1161-2003A patent/SK11612003A3/sk unknown
- 2002-02-13 WO PCT/EP2002/001567 patent/WO2002066484A1/en not_active Ceased
- 2002-02-13 JP JP2002565998A patent/JP3953424B2/ja not_active Expired - Lifetime
- 2002-02-13 DE DE60214138T patent/DE60214138T2/de not_active Expired - Lifetime
- 2002-02-13 HR HR20030647A patent/HRP20030647A2/hr not_active Application Discontinuation
- 2002-02-19 EG EG20020197A patent/EG23929A/xx active
- 2002-02-19 MY MYPI20020548A patent/MY137836A/en unknown
- 2002-02-20 TW TW091102853A patent/TWI257392B/zh not_active IP Right Cessation
- 2002-02-20 AR ARP020100583A patent/AR035685A1/es unknown
2003
- 2003-07-08 BG BG107984A patent/BG107984A/bg unknown
- 2003-08-19 IL IL157470A patent/IL157470A/en unknown
- 2003-08-20 NO NO20033700A patent/NO20033700L/no not_active Application Discontinuation
2006
- 2006-11-22 CY CY20061101693T patent/CY1106448T1/el unknown

Also Published As

Publication number	Publication date
DK1368358T3 (da)	2007-01-02
IL157470A (en)	2008-07-08
NZ526741A (en)	2004-04-30
MXPA03007432A (es)	2003-11-18
PT1368358E (pt)	2007-01-31
KR100848898B1 (ko)	2008-07-29
HUP0303270A2 (hu)	2004-01-28
NO20033700L (no)	2003-10-21
AR035685A1 (es)	2004-06-23
CA2437505A1 (en)	2002-08-29
HRP20030647A2 (en)	2005-06-30
NO20033700D0 (no)	2003-08-20
WO2002066484A1 (en)	2002-08-29
CA2437505C (en)	2010-02-09
CN1492871A (zh)	2004-04-28
IL157470A0 (en)	2004-03-28
ES2271230T3 (es)	2007-04-16
JP3953424B2 (ja)	2007-08-08
DE60214138T2 (de)	2007-03-29
US7169786B2 (en)	2007-01-30
EG23929A (en)	2008-01-14
CN100400540C (zh)	2008-07-09
BR0207433A (pt)	2004-06-01
AU2002244717B2 (en)	2007-07-19
ATE337322T1 (de)	2006-09-15
TWI257392B (en)	2006-07-01
EP1368358A1 (en)	2003-12-10
DE60214138D1 (de)	2006-10-05
EE200300398A (et)	2003-12-15
SK11612003A3 (sk)	2004-04-06
EA006747B1 (ru)	2006-04-28
PL208593B1 (pl)	2011-05-31
HUP0303270A3 (en)	2007-03-28
MY137836A (en)	2009-03-31
SI1368358T1 (sl)	2007-02-28
HK1065537A1 (zh)	2005-02-25
US20040122037A1 (en)	2004-06-24
JP2004518748A (ja)	2004-06-24
BG107984A (bg)	2004-09-30
CZ20032515A3 (cs)	2003-12-17
EP1368358B1 (en)	2006-08-23
KR20030076590A (ko)	2003-09-26
EA200300915A1 (ru)	2004-06-24
CY1106448T1 (el)	2011-10-12

Publication	Publication Date	Title
EG25755A (en)	2012-06-26	Oxazol deriatives
IL158517A0 (en)	2004-05-12	Novel 4-anilinoquinoline-3-carboxamides
ZA200309522B (en)	2005-02-23	Substituted cyclohexane-1-4diamine derivatives
IL160701A0 (en)	2004-08-31	3-substituted-4-pyrimidone derivatives
IL158388A0 (en)	2004-05-12	Novel arylheteroalkylamine derivatives
GB0126158D0 (en)	2002-01-02	Thin autotensioner
EP1353546A4 (en)	2009-07-22	METHOD AND DEVICE FOR MONITORING PULSATION FOR TREATMENT DEVICE
HUP0303449A3 (en)	2005-02-28	Substituted benzofuran-2-carboxamides derivatives
IL157470A0 (en)	2004-03-28	Isoxazoline derivatives as anti-depressants
HUP0401949A3 (en)	2009-07-28	4-imidazolin-2-one derivatives
HUP0303186A3 (en)	2007-06-28	4-aminobenzopyran derivatives
HUP0500026A3 (en)	2008-02-28	N-heteroarylnicotinamide derivatives
IL159064A0 (en)	2004-05-12	New phenylalkyloxy- phenyl derivatives
GB0104554D0 (en)	2001-04-11	New uses
AU2002335061A1 (en)	2003-04-28	Hookworm vaccine
EP1364954A4 (en)	2009-10-28	Dicarba closo DODECARBORANDERIVATE
GB0324680D0 (en)	2003-11-26	Cementitios mixtures
EG23036A (en)	2004-01-31	Novel pyrrolecarboxamides
GB2388047B (en)	2005-06-01	Game
PL364076A1 (pl)	2004-12-13	Nowe pirydylometyloaminopirymidyny
GB0103763D0 (en)	2001-04-04	Pak-Gep Construct
ZA200306487B (en)	2004-11-22	Isoxazoline derivatives as anti-depressants.
GB0130856D0 (en)	2002-02-06	Game
CA93273S (en)	2001-08-31	Sparkler
GB0117866D0 (en)	2001-09-12	Cartenoid Expression