PL364596A1 - Polipeptydy syntetazy tryptofanylo-tRNA użytecznew regulowaniu angiogenezy - Google Patents

Polipeptydy syntetazy tryptofanylo-tRNA użytecznew regulowaniu angiogenezy

Info

Publication number
PL364596A1
PL364596A1 PL02364596A PL36459602A PL364596A1 PL 364596 A1 PL364596 A1 PL 364596A1 PL 02364596 A PL02364596 A PL 02364596A PL 36459602 A PL36459602 A PL 36459602A PL 364596 A1 PL364596 A1 PL 364596A1
Authority
PL
Poland
Prior art keywords
angiogenesis
tryptophanyl
regulation
polypeptide
sequence
Prior art date
Application number
PL02364596A
Other languages
English (en)
Other versions
PL208008B1 (pl
Inventor
Paul Schimmel
Keisuke Wakasugi
Martin Friedlander
Original Assignee
The Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Scripps Research Institute filed Critical The Scripps Research Institute
Publication of PL364596A1 publication Critical patent/PL364596A1/pl
Publication of PL208008B1 publication Critical patent/PL208008B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y601/00—Ligases forming carbon-oxygen bonds (6.1)
    • C12Y601/01—Ligases forming aminoacyl-tRNA and related compounds (6.1.1)
    • C12Y601/01002—Tryptophan-tRNA ligase (6.1.1.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL364596A 2001-02-23 2002-02-22 Izolowany polipeptyd i jego zastosowanie, izolowany polinukleotyd, rekombinowany wektor, rekombinowana komórka gospodarza, kompozycja angiostatyczna i zestaw do hamowania neowaskularyzacji ocznej PL208008B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27095101P 2001-02-23 2001-02-23

Publications (2)

Publication Number Publication Date
PL364596A1 true PL364596A1 (pl) 2004-12-13
PL208008B1 PL208008B1 (pl) 2011-03-31

Family

ID=23033541

Family Applications (1)

Application Number Title Priority Date Filing Date
PL364596A PL208008B1 (pl) 2001-02-23 2002-02-22 Izolowany polipeptyd i jego zastosowanie, izolowany polinukleotyd, rekombinowany wektor, rekombinowana komórka gospodarza, kompozycja angiostatyczna i zestaw do hamowania neowaskularyzacji ocznej

Country Status (18)

Country Link
US (1) US20030017564A1 (pl)
EP (2) EP2080520A1 (pl)
JP (2) JP4361734B2 (pl)
KR (1) KR100869914B1 (pl)
CN (1) CN100486992C (pl)
AT (1) ATE420653T1 (pl)
AU (2) AU2002306558B2 (pl)
BR (1) BR0207449A (pl)
CA (1) CA2438273C (pl)
DE (1) DE60230860D1 (pl)
ES (1) ES2318063T3 (pl)
IL (3) IL157558A0 (pl)
MX (1) MXPA03007586A (pl)
NZ (1) NZ528193A (pl)
PL (1) PL208008B1 (pl)
RU (1) RU2297425C2 (pl)
WO (1) WO2002067970A1 (pl)
ZA (1) ZA200307383B (pl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8282921B2 (en) 2004-08-02 2012-10-09 Paul Glidden tRNA synthetase fragments

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US6903189B2 (en) * 2001-03-21 2005-06-07 The Scripps Research Institute Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis
US20060104963A1 (en) * 2002-07-25 2006-05-18 The Scripps Research Institute Treatment of cone cell degeneration with transfected lineage negative hematopoietic stem cells
US20060104962A1 (en) * 2002-07-25 2006-05-18 The Scripps Research Institute Transfected hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
US7838290B2 (en) * 2002-07-25 2010-11-23 The Scripps Research Institute Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
MXPA05000972A (es) * 2002-07-25 2005-09-12 Scripps Research Inst Celulas madres hematopoyeticas y metodo de tratamiento de enfermedades oculares neovasculares con las mismas.
KR101224368B1 (ko) * 2004-06-04 2013-01-22 더 스크립스 리서치 인스티튜트 혈관신생 질환 치료용 조성물 및 방법
US20060079474A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Analogs of tRNA synthetase fragments and uses thereof
US20060078553A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Diverse multi-unit complexes including a tRNA synthetase fragment
US20060079473A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Multi-unit complexes and uses thereof
US20060024288A1 (en) * 2004-08-02 2006-02-02 Pfizer Inc. tRNA synthetase fragments
US20060079673A1 (en) * 2004-08-02 2006-04-13 Paul Glidden Polynucleotides encoding tRNA synthetase fragments and uses thereof
US20060078886A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Business methods for modulating angiogenesis
US20060079672A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Kits for modulating angiogenesis
US20060024286A1 (en) * 2004-08-02 2006-02-02 Paul Glidden Variants of tRNA synthetase fragments and uses thereof
US20060079472A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Methods for treating angiogenesis
US20060079441A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Methods of modulating angiogenesis
US20060078556A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Antibodies and epitopes specific to tRNA synthetase fragments
DE102004054835A1 (de) * 2004-11-12 2006-05-24 VACUTEC Hochvakuum- & Präzisionstechnik GmbH Verfahren zur Herstellung einer Elektrode bzw. mehrpoligen Elektrodenanordnung sowie mehrpolige Elektrodenanordnung und Elektrode für eine mehrpolige Elektrodenanordnung
RU2401124C2 (ru) * 2005-02-24 2010-10-10 Дзе Скриппс Рисерч Инститьют Реваскуляризация ишемической ткани сетчатки и способ ее скрининга
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WO2010099477A2 (en) 2009-02-27 2010-09-02 Atyr Pharma, Inc. Polypeptide structural motifs associated with cell signaling activity
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JP6240500B2 (ja) 2010-04-27 2017-11-29 エータイアー ファーマ， インコーポレイテッド スレオニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
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CN103097524B (zh) 2010-04-28 2016-08-03 Atyr医药公司 与丙氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
AU2011248457B2 (en) 2010-04-29 2017-02-16 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl tRNA synthetases
US8986680B2 (en) 2010-04-29 2015-03-24 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases
WO2011139988A2 (en) 2010-05-03 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of seryl-trna synthetases
ES2623805T3 (es) 2010-05-03 2017-07-12 Atyr Pharma, Inc. Descubrimiento innovador de composiciones terapéuticas, de diagnóstico y de anticuerpos relacionadas con fragmentos de proteínas de fenilalanil-alfa-ARNt sintetasas
EP2566496B1 (en) 2010-05-03 2018-02-28 aTyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-trna synthetases
CN103096925A (zh) 2010-05-03 2013-05-08 Atyr医药公司 与精氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
CN102985103A (zh) 2010-05-04 2013-03-20 Atyr医药公司 与p38多-tRNA合成酶复合物相关的治疗、诊断和抗体组合物的创新发现
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CA2799197C (en) 2010-05-14 2019-10-29 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-trna synthetases
CA2799480C (en) 2010-05-17 2020-12-15 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-trna synthetases
CA2800375C (en) 2010-05-27 2021-03-09 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-trna synthetases
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8282921B2 (en) 2004-08-02 2012-10-09 Paul Glidden tRNA synthetase fragments

Also Published As

Publication number Publication date
US20030017564A1 (en) 2003-01-23
IL157558A (en) 2010-06-16
RU2003128420A (ru) 2005-02-20
NZ528193A (en) 2006-02-24
KR100869914B1 (ko) 2008-11-21
IL201755A (en) 2015-01-29
PL208008B1 (pl) 2011-03-31
ZA200307383B (en) 2005-03-30
ATE420653T1 (de) 2009-01-15
WO2002067970A1 (en) 2002-09-06
IL157558A0 (en) 2004-03-28
CN100486992C (zh) 2009-05-13
RU2297425C2 (ru) 2007-04-20
EP1377305B1 (en) 2009-01-14
EP2080520A1 (en) 2009-07-22
CN1527719A (zh) 2004-09-08
JP4448925B2 (ja) 2010-04-14
AU2007219318B2 (en) 2009-12-17
CA2438273C (en) 2013-06-18
KR20030078935A (ko) 2003-10-08
CA2438273A1 (en) 2002-09-06
JP2009261409A (ja) 2009-11-12
EP1377305A1 (en) 2004-01-07
MXPA03007586A (es) 2003-12-11
JP2004532010A (ja) 2004-10-21
DE60230860D1 (de) 2009-03-05
EP1377305A4 (en) 2005-02-09
AU2002306558B2 (en) 2007-06-28
HK1069322A1 (zh) 2005-05-20
JP4361734B2 (ja) 2009-11-11
BR0207449A (pt) 2004-04-06
ES2318063T3 (es) 2009-05-01
AU2007219318A1 (en) 2007-10-18

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