PL365254A1 - Pochodne benzo[g]chinoliny do leczenia jaskry i krótkowzroczności - Google Patents

Pochodne benzo[g]chinoliny do leczenia jaskry i krótkowzroczności

Info

Publication number
PL365254A1
PL365254A1 PL02365254A PL36525402A PL365254A1 PL 365254 A1 PL365254 A1 PL 365254A1 PL 02365254 A PL02365254 A PL 02365254A PL 36525402 A PL36525402 A PL 36525402A PL 365254 A1 PL365254 A1 PL 365254A1
Authority
PL
Poland
Prior art keywords
myopia
benzo
quinoline derivatives
treating glaucoma
glaucoma
Prior art date
Application number
PL02365254A
Other languages
English (en)
Other versions
PL208284B1 (pl
Inventor
Rudolf Markstein
Peter Gull
Villar Esteban Pombo
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL365254A1 publication Critical patent/PL365254A1/pl
Publication of PL208284B1 publication Critical patent/PL208284B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL365254A 2001-07-09 2002-07-08 Pochodne benzo[g]chinoliny, kompozycje je zawierające oraz zastosowanie takich pochodnych PL208284B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01116553 2001-07-09
PCT/EP2002/007594 WO2003006458A1 (en) 2001-07-09 2002-07-08 Benzo [g] quinoline derivatives for treating glaucoma and myopia

Publications (2)

Publication Number Publication Date
PL365254A1 true PL365254A1 (pl) 2004-12-27
PL208284B1 PL208284B1 (pl) 2011-04-29

Family

ID=8177978

Family Applications (1)

Application Number Title Priority Date Filing Date
PL365254A PL208284B1 (pl) 2001-07-09 2002-07-08 Pochodne benzo[g]chinoliny, kompozycje je zawierające oraz zastosowanie takich pochodnych

Country Status (25)

Country Link
US (1) US7105528B2 (pl)
EP (1) EP1419149B1 (pl)
JP (2) JP5006505B2 (pl)
KR (2) KR101069948B1 (pl)
CN (1) CN1293071C (pl)
AR (1) AR036131A1 (pl)
AT (1) ATE443060T1 (pl)
AU (1) AU2002328856B2 (pl)
BR (1) BR0210894A (pl)
CA (1) CA2452920C (pl)
DE (1) DE60233740D1 (pl)
EC (1) ECSP024377A (pl)
ES (1) ES2330732T3 (pl)
HU (1) HUP0400833A3 (pl)
IL (2) IL159255A0 (pl)
MX (1) MXPA03012039A (pl)
MY (1) MY130656A (pl)
NO (1) NO327549B1 (pl)
NZ (1) NZ530314A (pl)
PE (1) PE20030240A1 (pl)
PL (1) PL208284B1 (pl)
PT (1) PT1419149E (pl)
RU (1) RU2300532C2 (pl)
WO (1) WO2003006458A1 (pl)
ZA (1) ZA200309642B (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EG24415A (en) * 2002-03-07 2009-05-25 Novartis Ag Quinoline derivatives
JP2007504198A (ja) * 2003-09-05 2007-03-01 ノバルティス アクチエンゲゼルシャフト ベンゾ［ｇ］キノリン誘導体とプロスタグランジン誘導体を含む、組成物
RU2438670C1 (ru) * 2010-12-24 2012-01-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Ростовский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО "РостГМУ" Минздравсоцразвития России) Способ лечения ишемического варианта первичной открытоугольной глаукомы у лиц с миопической рефракцией
PT3713933T (pt) 2017-11-24 2026-05-19 H Lundbeck As Novos profrmacos de catecolamina para utilizao no tratamento de doena de parkinson
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
EP3972600B1 (en) 2019-05-21 2026-02-18 H. Lundbeck A/S Catecholamine carbamate prodrugs for use in the treatment of parkinson s disease
JP7641234B2 (ja) 2019-05-21 2025-03-06 ハー・ルンドベック・アクチエゼルスカベット パーキンソン病の治療に使用するための新規なカテコールアミンプロドラッグ
US12391650B2 (en) 2019-05-21 2025-08-19 H. Lundbeck A/S Catecholamine prodrugs for use in the treatment of Parkinson's disease
WO2020234275A1 (en) 2019-05-21 2020-11-26 H. Lundbeck A/S New catecholamine prodrugs for use in the treatment of parkinson's diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262422A (en) * 1991-05-02 1993-11-16 Sandoz Ltd. Octahydrobenzo[g]quinoline
DE4114325A1 (de) * 1991-05-02 1992-11-05 Sandoz Ag Octahydrobenzo(g)chinolin, seine herstellung und verwendung
GB9326010D0 (en) 1993-12-21 1994-02-23 Sandoz Ltd Improvements in or relating to organic compounds
TW357143B (en) * 1995-07-07 1999-05-01 Novartis Ag Benzo[g]quinoline derivatives
TW378209B (en) * 1996-07-08 2000-01-01 Novartis Ag Benzo[g]quinoline derivatives, their preparation and the pharmaceutical composition containing them

Also Published As

Publication number Publication date
ZA200309642B (en) 2004-10-04
JP2010024243A (ja) 2010-02-04
DE60233740D1 (de) 2009-10-29
HK1066211A1 (en) 2005-03-18
US20040171628A1 (en) 2004-09-02
BR0210894A (pt) 2004-06-22
ATE443060T1 (de) 2009-10-15
CA2452920C (en) 2010-03-30
NO20040059L (no) 2004-01-07
NZ530314A (en) 2005-08-26
HUP0400833A2 (hu) 2004-07-28
CN1293071C (zh) 2007-01-03
PT1419149E (pt) 2009-11-25
MXPA03012039A (es) 2004-03-26
HUP0400833A3 (en) 2010-03-29
RU2004102398A (ru) 2005-07-10
WO2003006458A1 (en) 2003-01-23
NO327549B1 (no) 2009-08-10
RU2300532C2 (ru) 2007-06-10
JP2004538278A (ja) 2004-12-24
US7105528B2 (en) 2006-09-12
PE20030240A1 (es) 2003-04-16
KR20040013126A (ko) 2004-02-11
PL208284B1 (pl) 2011-04-29
MY130656A (en) 2007-07-31
EP1419149A1 (en) 2004-05-19
IL159255A (en) 2010-05-17
IL159255A0 (en) 2004-06-01
KR20100007983A (ko) 2010-01-22
ECSP024377A (es) 2004-08-27
AR036131A1 (es) 2004-08-11
ES2330732T3 (es) 2009-12-15
JP5006505B2 (ja) 2012-08-22
KR101069948B1 (ko) 2011-10-04
EP1419149B1 (en) 2009-09-16
AU2002328856B2 (en) 2005-08-04
CA2452920A1 (en) 2003-01-23
CN1525969A (zh) 2004-09-01

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Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20110708

LAPS Decisions on the lapse of the protection rights

Effective date: 20140708