PL366636A1 - Piranoindazole i ich zastosowanie w leczeniu jaskry - Google Patents

Piranoindazole i ich zastosowanie w leczeniu jaskry

Info

Publication number
PL366636A1
PL366636A1 PL02366636A PL36663602A PL366636A1 PL 366636 A1 PL366636 A1 PL 366636A1 PL 02366636 A PL02366636 A PL 02366636A PL 36663602 A PL36663602 A PL 36663602A PL 366636 A1 PL366636 A1 PL 366636A1
Authority
PL
Poland
Prior art keywords
pyranoindazoles
glaucoma
treatment
Prior art date
Application number
PL02366636A
Other languages
English (en)
Inventor
Hwang-Hsing Chen
Jesse A. May
Bryon S. Severns
Original Assignee
Alcon, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon, Inc. filed Critical Alcon, Inc.
Publication of PL366636A1 publication Critical patent/PL366636A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL02366636A 2001-06-01 2002-05-30 Piranoindazole i ich zastosowanie w leczeniu jaskry PL366636A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29542901P 2001-06-01 2001-06-01

Publications (1)

Publication Number Publication Date
PL366636A1 true PL366636A1 (pl) 2005-02-07

Family

ID=23137684

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02366636A PL366636A1 (pl) 2001-06-01 2002-05-30 Piranoindazole i ich zastosowanie w leczeniu jaskry

Country Status (19)

Country Link
US (2) US6696476B2 (pl)
EP (1) EP1392292B1 (pl)
JP (1) JP2004535418A (pl)
KR (1) KR100626255B1 (pl)
CN (1) CN100384417C (pl)
AR (1) AR036044A1 (pl)
AT (1) ATE318821T1 (pl)
AU (1) AU2002305732B2 (pl)
BR (1) BR0210241A (pl)
CA (1) CA2447480A1 (pl)
DE (1) DE60209486T2 (pl)
DK (1) DK1392292T3 (pl)
ES (1) ES2258631T3 (pl)
MX (1) MXPA03010807A (pl)
PL (1) PL366636A1 (pl)
PT (1) PT1392292E (pl)
RU (1) RU2273641C2 (pl)
WO (1) WO2002098350A2 (pl)
ZA (1) ZA200309034B (pl)

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US7005443B1 (en) * 2000-03-17 2006-02-28 Alcon, Inc. 5-Hydroxy indazole derivatives for treating glaucoma
ATE317846T1 (de) * 2000-03-31 2006-03-15 Purdue Research Foundation Phosphoramidat-prodrugs
ATE318821T1 (de) * 2001-06-01 2006-03-15 Alcon Inc Pyranoindazole und ihre verwendung in der glaukombehandlung
TW593302B (en) 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
AU2002360819A1 (en) * 2001-12-28 2003-07-24 Bayer Corporation Cyclohexano- and cycloheptapyrazole derivative compounds, for use in diseases associated with the 5-ht2c receptor
MXPA05002259A (es) * 2002-08-30 2005-07-05 Alcon Inc Compuestos de 5-croman-5-il-etilamina sustituidos y uso para el tratamiento de glaucoma.
EP1581209A4 (en) 2002-12-13 2009-03-11 Alcon Inc NEW BENZOPYRAN ANALOGUE AND ITS USE FOR THE TREATMENT OF GLAUKOM
AU2004271978B2 (en) * 2003-09-04 2009-02-05 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
WO2005053688A1 (en) * 2003-11-26 2005-06-16 Alcon, Inc. Substituted furo[2,3-g] indazoles for the treatment of glaucoma
US7129257B1 (en) 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
AR046890A1 (es) 2003-12-15 2005-12-28 Alcon Inc [1,4] oxazino [2,3-g] indazoles sustituidos para el tratamiento del glaucoma.
EP1792629A4 (en) 2004-08-25 2010-08-25 Takeda Pharmaceutical MEANS FOR THE PREVENTION / TREATMENT OF STRESS-RELATED HARNINE INCONTINENCE AND PRECAUTIONARY METHOD FOR THIS
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
US7425572B2 (en) 2004-12-08 2008-09-16 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
TW200744567A (en) * 2005-09-23 2007-12-16 Alcon Inc Phenylethylamine analogs and their use for treating glaucoma
EP2727585A1 (en) 2006-05-16 2014-05-07 Takeda Pharmaceutical Company Limited In-vivo screening method
US20070293475A1 (en) * 2006-06-20 2007-12-20 Alcon Manufacturing Ltd. Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma
MX2009001037A (es) * 2006-07-31 2009-05-15 Senju Pharma Co Preparacion liquida acuosa que contiene compuesto de amida.
WO2008016993A1 (en) * 2006-08-01 2008-02-07 Alcon Research, Ltd. Intermediates and methods for serotonergic agonist synthesis
WO2008016989A1 (en) * 2006-08-01 2008-02-07 Alcon Research, Ltd. Process for preparing pyranoindazole serotonergic receptor agonists
US20080058533A1 (en) * 2006-08-31 2008-03-06 Alcon, Inc. Pyranoindazole cyclic carbonates and methods of use
EP2216023A4 (en) 2007-11-15 2013-03-13 Takeda Pharmaceutical CONDENSED PYRIDINE DERIVATIVE AND ITS USE
JPWO2011071136A1 (ja) 2009-12-11 2013-04-22 アステラス製薬株式会社 線維筋痛症治療剤
WO2016139960A1 (ja) * 2015-03-05 2016-09-09 株式会社ブリヂストン ゴム組成物、ジエン系重合体の製造方法及びタイヤ
TW201815766A (zh) * 2016-09-22 2018-05-01 美商普雷辛肯公司 用於ｉｄｏ及ｔｄｏ調節之化合物及方法以及其適應症
JPWO2019131902A1 (ja) 2017-12-27 2020-12-10 武田薬品工業株式会社 腹圧性尿失禁および便失禁の治療薬
US11149011B2 (en) 2018-03-20 2021-10-19 Plexxikon Inc. Compounds and methods for IDO and TDO modulation, and indications therefor

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AU4249297A (en) * 1996-10-31 1998-05-22 Alcon Laboratories, Inc. Opthalmological compositions containing serotonin 5-ht1a receptor agonist and their use in the treatment of glaucoma
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DK1112106T3 (da) 1998-09-18 2005-12-12 Alcon Mfg Ltd Serotonerge 5HT2-agonister til behandling af glaukom
IL143323A0 (en) 1998-12-17 2002-04-21 American Home Prod 2,3,4,4a-tetrahydro-1h-pyrazino (1,2-a) quinoxalin-5 (6h) one derivatives being 5ht2c agonists
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ATE318821T1 (de) * 2001-06-01 2006-03-15 Alcon Inc Pyranoindazole und ihre verwendung in der glaukombehandlung

Also Published As

Publication number Publication date
CA2447480A1 (en) 2002-12-12
KR100626255B1 (ko) 2006-09-21
DE60209486D1 (de) 2006-04-27
US20030171418A1 (en) 2003-09-11
RU2273641C2 (ru) 2006-04-10
ES2258631T3 (es) 2006-09-01
US6696476B2 (en) 2004-02-24
RU2003137825A (ru) 2005-04-20
BR0210241A (pt) 2004-08-10
KR20040010669A (ko) 2004-01-31
US20040106609A1 (en) 2004-06-03
WO2002098350A2 (en) 2002-12-12
ZA200309034B (en) 2004-07-16
AR036044A1 (es) 2004-08-04
DK1392292T3 (da) 2006-05-29
AU2002305732B2 (en) 2007-02-01
WO2002098350A3 (en) 2003-02-27
JP2004535418A (ja) 2004-11-25
CN1592619A (zh) 2005-03-09
US6881749B2 (en) 2005-04-19
EP1392292A2 (en) 2004-03-03
MXPA03010807A (es) 2004-11-22
HK1061212A1 (en) 2004-09-10
EP1392292B1 (en) 2006-03-01
EP1392292A4 (en) 2004-08-11
DE60209486T2 (de) 2006-08-03
CN100384417C (zh) 2008-04-30
ATE318821T1 (de) 2006-03-15
PT1392292E (pt) 2006-05-31

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