PL366631A1 - Podstawione pochodne cykloheksano-1,4-diaminy o działaniu przeciwbiegunkowym i obwodowym przeciwbólowym - Google Patents

Podstawione pochodne cykloheksano-1,4-diaminy o działaniu przeciwbiegunkowym i obwodowym przeciwbólowym

Info

Publication number: PL366631A1
Authority: PL; Poland
Prior art keywords: constipating; analgesic properties; diamine derivatives; peripheral analgesic; substituted cyclohexan
Prior art date: 2001-05-09

Application number

PL02366631A

Other languages

English (en)

Inventor

Elmar Josef Friderichs

Bernd Sundermann

Claudia Hinze

Babette-Yvonne Kögel

Original Assignee

Grünenthal GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-09

Filing date

2002-05-09

Publication date

2005-02-07

2002-05-09 Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH

2005-02-07 Publication of PL366631A1 publication Critical patent/PL366631A1/pl

Links

230000000202 analgesic effect Effects 0.000 title 1
VKIRRGRTJUUZHS-UHFFFAOYSA-N cyclohexane-1,4-diamine Chemical class NC1CCC(N)CC1 VKIRRGRTJUUZHS-UHFFFAOYSA-N 0.000 title 1
230000002093 peripheral effect Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
- C07C211/36—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing at least two amino groups bound to the carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/132—Amines having two or more amino groups, e.g. spermidine, putrescine
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Addiction (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Immunology (AREA)
Hospice & Palliative Care (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Vascular Medicine (AREA)
Dermatology (AREA)
Nutrition Science (AREA)
Anesthesiology (AREA)
Child & Adolescent Psychology (AREA)

PL02366631A 2001-05-09 2002-05-09 Podstawione pochodne cykloheksano-1,4-diaminy o działaniu przeciwbiegunkowym i obwodowym przeciwbólowym PL366631A1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10123163A DE10123163A1 (de)	2001-05-09	2001-05-09	Substituierte Cyclohexan-1,4-diaminderivate

Publications (1)

Publication Number	Publication Date
PL366631A1 true PL366631A1 (pl)	2005-02-07

Family

ID=7684562

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
PL368851A PL212887B1 (pl)	2001-05-09	2002-05-08	Podstawione pochodne cykloheksano-1,4-diaminy
PL366662A PL220595B1 (pl)	2001-05-09	2002-05-08	Podstawione pochodne 2-pirydyno-cykloheksano-1,4-diaminy, sposób ich wytwarzania, zastosowanie oraz środek leczniczy zawierający te pochodne
PL02366631A PL366631A1 (pl)	2001-05-09	2002-05-09	Podstawione pochodne cykloheksano-1,4-diaminy o działaniu przeciwbiegunkowym i obwodowym przeciwbólowym

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
PL368851A PL212887B1 (pl)	2001-05-09	2002-05-08	Podstawione pochodne cykloheksano-1,4-diaminy
PL366662A PL220595B1 (pl)	2001-05-09	2002-05-08	Podstawione pochodne 2-pirydyno-cykloheksano-1,4-diaminy, sposób ich wytwarzania, zastosowanie oraz środek leczniczy zawierający te pochodne

Country Status (30)

Country	Link
US (3)	US20040229872A1 (pl)
EP (3)	EP1385825B1 (pl)
JP (3)	JP2004528374A (pl)
KR (2)	KR20040002943A (pl)
CN (2)	CN1533374B (pl)
AR (1)	AR035883A1 (pl)
AT (2)	ATE359260T1 (pl)
AU (3)	AU2002312883B2 (pl)
BR (2)	BR0209579A (pl)
CA (3)	CA2446461C (pl)
CO (2)	CO5700725A2 (pl)
CY (2)	CY1106468T1 (pl)
CZ (2)	CZ20033005A3 (pl)
DE (3)	DE10123163A1 (pl)
DK (2)	DK1385825T3 (pl)
EC (2)	ECSP034830A (pl)
ES (2)	ES2291486T3 (pl)
HU (3)	HU228253B1 (pl)
IL (4)	IL158784A0 (pl)
MX (3)	MXPA03010201A (pl)
NO (2)	NO328600B1 (pl)
NZ (2)	NZ529147A (pl)
PE (1)	PE20021094A1 (pl)
PL (3)	PL212887B1 (pl)
PT (2)	PT1385825E (pl)
RU (2)	RU2287523C2 (pl)
SI (2)	SI1392641T1 (pl)
SK (2)	SK287319B6 (pl)
WO (3)	WO2002090330A1 (pl)
ZA (2)	ZA200309521B (pl)

Families Citing this family (48)

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DE10252650A1 (de) *	2002-11-11	2004-05-27	Grünenthal GmbH	Cyclohexyl-Harnstoff-Derivate
DE10252665A1 (de)	2002-11-11	2004-06-03	Grünenthal GmbH	4-Aminomethyl-1-aryl-cyclohexylamin-Derivate
EP1560807B1 (de)	2002-11-12	2010-02-10	Grünenthal GmbH	4-hydroxymethyl-1-aryl-cyclohexylamin-derivative
CA2506415A1 (en)	2002-11-19	2004-06-03	Achillion Pharmaceuticals, Inc.	Substituted aryl thioureas and releated compounds; inhibitors of viral replication
US7026432B2 (en)	2003-08-12	2006-04-11	General Electric Company	Electrically conductive compositions and method of manufacture thereof
US7354988B2 (en)	2003-08-12	2008-04-08	General Electric Company	Electrically conductive compositions and method of manufacture thereof
US7378409B2 (en)	2003-08-21	2008-05-27	Bristol-Myers Squibb Company	Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity
US7309727B2 (en)	2003-09-29	2007-12-18	General Electric Company	Conductive thermoplastic compositions, methods of manufacture and articles derived from such compositions
DE10360792A1 (de) *	2003-12-23	2005-07-28	Grünenthal GmbH	Spirocyclische Cyclohexan-Derivate
DE10360793A1 (de) *	2003-12-23	2005-07-28	Grünenthal GmbH	Spirocyclische Cyclohexan-Derivate
DE102004023508A1 (de) *	2004-05-10	2005-12-08	Grünenthal GmbH	Säurederivate substituierter Cyclohexyl-1,4-diamine
DE102004023522A1 (de)	2004-05-10	2005-12-01	Grünenthal GmbH	Substituierte Cyclohexyl-1,4-diamin-Derivate
DE102004023501A1 (de)	2004-05-10	2005-12-01	Grünenthal GmbH	Oxosubstituierte Cyclohexyl-1,4-diamin-Derivate
DE102004023507A1 (de) *	2004-05-10	2005-12-01	Grünenthal GmbH	Substituierte Cyclohexylessigsäure-Derivate
DE102004023506A1 (de)	2004-05-10	2005-12-01	Grünenthal GmbH	Kettenverlängerte substituierte Cyclohexyl-1,4-diamin-Derivate
DE102004023632A1 (de) *	2004-05-10	2005-12-08	Grünenthal GmbH	Substituierte Cyclohexylcarbonsäure-Derivate
DE102004023635A1 (de)	2004-05-10	2006-04-13	Grünenthal GmbH	Heteroarylsubstituierte Cyclohexyl-1,4-diamin-Derivate
TW200600492A (en) *	2004-05-18	2006-01-01	Achillion Pharmaceuticals Inc	Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
US7462656B2 (en)	2005-02-15	2008-12-09	Sabic Innovative Plastics Ip B.V.	Electrically conductive compositions and method of manufacture thereof
DE102005061428A1 (de)	2005-12-22	2007-08-16	Grünenthal GmbH	Substituierte Cyclohexylmethyl-Derivate
DE102006033109A1 (de) *	2006-07-18	2008-01-31	Grünenthal GmbH	Substituierte Heteroaryl-Derivate
DE102006033114A1 (de)	2006-07-18	2008-01-24	Grünenthal GmbH	Spirocyclische Azaindol-Derivate
DE102006035787A1 (de)	2006-07-28	2008-03-13	Tesa Ag	Verfahren zum Stanzen von bei Raumtemperatur nicht tackigen hitzeaktivierbaren Klebmassen
US20080194557A1 (en) *	2007-01-18	2008-08-14	Joseph Barbosa	Methods and compositions for the treatment of pain, inflammation and cancer
CN101784274A (zh) *	2007-06-15	2010-07-21	米申制药公司	抑制水肿因子和腺苷酸环化酶的方法和组合物
US20090215725A1 (en) *	2008-02-26	2009-08-27	Grunenthal Gmbh	Substituted 4-aminocyclohexane derivatives
PE20091823A1 (es) *	2008-03-27	2009-12-10	Gruenenthal Chemie	Ciclohexildiaminas sustituidas
MX2010010407A (es)	2008-03-27	2010-10-25	Gruenenthal Gmbh	Derivados de 4-aminociclohexanos sustituidos.
PL2260042T3 (pl)	2008-03-27	2012-02-29	Gruenenthal Gmbh	Podstawione spirocykliczne pochodne cykloheksanu
DK2257526T3 (da)	2008-03-27	2012-02-06	Gruenenthal Gmbh	Spiro(5,5)undecan-derivater
RU2514192C2 (ru)	2008-03-27	2014-04-27	Грюненталь Гмбх	Гидроксиметилциклогексиламины
WO2009118163A1 (de)	2008-03-27	2009-10-01	Grünenthal GmbH	(hetero-)aryl-cyclohexan-derivate
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2001
- 2001-05-09 DE DE10123163A patent/DE10123163A1/de not_active Withdrawn
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Also Published As

Publication number	Publication date
PT1392641E (pt)	2007-05-31
HK1070049A1 (en)	2005-06-10
HUP0400989A3 (en)	2011-08-29
JP2005515959A (ja)	2005-06-02
ES2284876T3 (es)	2007-11-16
US20040229872A1 (en)	2004-11-18
DK1385825T3 (da)	2007-11-05
NZ529147A (en)	2006-10-27
NO326784B1 (no)	2009-02-16
EP1385493A1 (de)	2004-02-04
CA2446735A1 (en)	2002-11-14
MXPA03010134A (es)	2004-03-10
HUP0400888A2 (hu)	2004-07-28
CO5540300A2 (es)	2005-07-29
HUP0400888A3 (en)	2008-03-28
EP1385825B1 (de)	2007-08-15
KR20040017214A (ko)	2004-02-26
AU2007202033B2 (en)	2010-02-04
HU229288B1 (en)	2013-10-28
NO20034931D0 (no)	2003-11-05
HUP0400989A2 (hu)	2004-08-30
BR0209580A (pt)	2004-06-22
PL366662A1 (pl)	2005-02-07
ES2291486T3 (es)	2008-03-01
CA2446463A1 (en)	2002-11-14
CY1106468T1 (el)	2012-01-25
AU2007202033A1 (en)	2007-05-24
RU2003134147A (ru)	2005-05-20
PE20021094A1 (es)	2003-01-25
IL158782A0 (en)	2004-05-12
NO20034930D0 (no)	2003-11-05
PT1385825E (pt)	2007-09-04
US20040162287A1 (en)	2004-08-19
DK1392641T3 (da)	2007-07-16
US7276518B2 (en)	2007-10-02
NO20034931L (no)	2004-01-02
SI1392641T1 (sl)	2007-10-31
NO328600B1 (no)	2010-03-29
ATE370120T1 (de)	2007-09-15
NZ529334A (en)	2004-10-29
DE50209929D1 (de)	2007-05-24
SI1385825T1 (sl)	2008-02-29
EP1392641B1 (de)	2007-04-11
MXPA03010201A (es)	2006-02-09
AR035883A1 (es)	2004-07-21
ECSP034831A (es)	2004-03-23
RU2321579C2 (ru)	2008-04-10
CA2446461C (en)	2011-04-26
WO2002089783A1 (de)	2002-11-14
BR0209579A (pt)	2004-06-22
CA2446463C (en)	2010-07-13
CO5700725A2 (es)	2006-11-30
SK13782003A3 (sk)	2004-04-06
SK13792003A3 (sk)	2004-06-08
AU2002312883B2 (en)	2007-09-06
RU2003134145A (ru)	2005-05-20
US20040147741A1 (en)	2004-07-29
HU228253B1 (en)	2013-02-28
PL212887B1 (pl)	2012-12-31
CY1108067T1 (el)	2014-02-12
CA2446461A1 (en)	2002-11-14
DE10123163A1 (de)	2003-01-16
ECSP034830A (es)	2004-03-23
CN1537100A (zh)	2004-10-13
SK287319B6 (sk)	2010-07-07
KR100895778B1 (ko)	2009-05-08
EP1392641A1 (de)	2004-03-03
KR20040002943A (ko)	2004-01-07
PL220595B1 (pl)	2015-11-30
WO2002090317A1 (de)	2002-11-14
CN1307158C (zh)	2007-03-28
ATE359260T1 (de)	2007-05-15
AU2007202033B8 (en)	2010-03-04
WO2002090330A1 (de)	2002-11-14
JP2004533439A (ja)	2004-11-04
ZA200309522B (en)	2005-02-23
JP2004528374A (ja)	2004-09-16
IL158784A (en)	2009-09-01
IL158784A0 (en)	2004-05-12
PL368851A1 (pl)	2005-04-04
RU2287523C2 (ru)	2006-11-20
SK286617B6 (sk)	2009-02-05
AU2002341195B2 (en)	2007-01-04
HUP0400963A2 (hu)	2004-08-30
DE50210707D1 (de)	2007-09-27
CN1533374B (zh)	2013-08-21
EP1385825A1 (de)	2004-02-04
ZA200309521B (en)	2004-09-28
CN1533374A (zh)	2004-09-29
MXPA03010195A (es)	2004-03-10
HK1062911A1 (en)	2004-12-03
NO20034930L (no)	2004-01-05
CZ20032995A3 (cs)	2004-02-18
CZ20033005A3 (en)	2004-03-17
US6998409B2 (en)	2006-02-14
IL158782A (en)	2010-04-15

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PL366631A1 (pl)	2005-02-07	Podstawione pochodne cykloheksano-1,4-diaminy o działaniu przeciwbiegunkowym i obwodowym przeciwbólowym
PL375764A1 (pl)	2005-12-12	Indazole, benzotiazole i benzoizotiazole, sposób ich wytwarzania oraz ich zastosowanie
MXPA03001928A (es)	2003-06-19	Derivados de quinolina y quinazolina.
MXPA03006260A (es)	2003-09-22	Derivados de amina sustituidos y metodos de uso.
IL166100A0 (en)	2006-01-15	7,8,9-10-tetrahydro-6h-azepino,6,7,8,9-tetrahydro-pyrido and 2,3-dihydro-2h-pyrroloÄ2,1-bÜ quinazolinone derivatives
AU4060500A (en)	2000-10-16	Advanced law enforcement and response technology
PL377296A1 (pl)	2006-01-23	Pochodne 1,5-diarylo-pirolo-3-karboksyamidu oraz ich zastosowanie jako modulatorów receptora kannabinoidowego
AU2002359126A1 (en)	2003-06-30	Benzodiazepine derivatives, preparation thereof and use thereof
AU2001247705A1 (en)	2001-10-03	Security flashlight and method
IL157662A0 (en)	2004-03-28	N-but-3-enyl norbuprenorphine and its use as analgesic
AU2002359123A1 (en)	2003-06-30	Benzodiazepine derivatives, preparation thereof and use thereof
PL370657A1 (pl)	2005-05-30	Pochodne chinazolinonowe i ich zastosowanie jako agonistów CB
IL158254A0 (en)	2004-05-12	Indolinones, substituted in position 6, and their use as kinase inhibitors
AU2002343103A1 (en)	2003-06-10	Aminoalkylimidazole derivatives and their use in medicine
AU2003299943A1 (en)	2004-07-22	Heterocycles and uses thereof
HUP0302065A3 (en)	2005-07-28	Chromanone derivatives, production and use thereof
HUP0600238A3 (en)	2009-12-28	Benzothiazole- and benzoxazole-4,7-dione derivatives and their use
IL158121A0 (en)	2004-03-28	5-membered heterocycles, preparation and application thereof as medicaments
TWI348382B (en)	2011-09-11	N-acetylglucosamine derivatives, and the use thereof
EP1407771A4 (en)	2006-03-22	SOPHORIDINE AND ITS USE AS ANALYZIC
HUP0201035A3 (en)	2006-03-28	Substituted bezimidazole, the production thereof and the use thereof as means against parasitic protozoa
AU2002341210A1 (en)	2002-11-18	Substituted cyclohexan-1,4-diamine derivatives with constipating and peripheral analgesic properties
AU2003300262A1 (en)	2004-07-14	Phthalimidylazo dyes, processes for the preparation thereof and the use thereof
PL367535A1 (pl)	2005-02-21	Podstawione pochodne C-furan-2-ylo-metyloaminy i C-tiofen-2-ylo-metyloaminy
AU2002329017A1 (en)	2003-03-10	Protective factors against inflammation, burns and noxious stimuli