PL369148A1 - Produkt zawierający mikanolid, dihydromikanolid lub ich analog w kombinacji z innym środkiem przeciwrakowym do stosowania terapeutycznego w leczeniu raka - Google Patents
Produkt zawierający mikanolid, dihydromikanolid lub ich analog w kombinacji z innym środkiem przeciwrakowym do stosowania terapeutycznego w leczeniu rakaInfo
- Publication number
- PL369148A1 PL369148A1 PL02369148A PL36914802A PL369148A1 PL 369148 A1 PL369148 A1 PL 369148A1 PL 02369148 A PL02369148 A PL 02369148A PL 36914802 A PL36914802 A PL 36914802A PL 369148 A1 PL369148 A1 PL 369148A1
- Authority
- PL
- Poland
- Prior art keywords
- dihydromikanolide
- mikanolide
- analogue
- combined
- product
- Prior art date
Links
- UOQXZMNXWXQCJU-XMOWUHPBSA-N Dihydromikanolide Chemical compound C([C@H]1[C@H]2[C@H](C(O1)=O)C)[C@]1(C)O[C@H]1[C@@H]1O[C@@H]1C1=C[C@H]2OC1=O UOQXZMNXWXQCJU-XMOWUHPBSA-N 0.000 title 1
- UOQXZMNXWXQCJU-VUUDCVLBSA-N Dihydromikanolide Natural products O=C1[C@@H](C)[C@H]2[C@H]3OC(=O)C([C@H]4O[C@H]4[C@H]4[C@@](C)(O4)C[C@@H]2O1)=C3 UOQXZMNXWXQCJU-VUUDCVLBSA-N 0.000 title 1
- JRZGAAFGODYEEA-UHFFFAOYSA-N Mikanolid Natural products C12OC2C(O2)C2(C)CC2OC(=O)C(=C)C2C2OC(=O)C1=C2 JRZGAAFGODYEEA-UHFFFAOYSA-N 0.000 title 1
- JRZGAAFGODYEEA-ATNXOXLHSA-N Mikanolide Chemical compound C([C@]1([C@H]([C@@H]2O[C@@H]22)O1)C)[C@@H]1OC(=O)C(=C)[C@H]1[C@@H]1OC(=O)C2=C1 JRZGAAFGODYEEA-ATNXOXLHSA-N 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0107104A FR2825278A1 (fr) | 2001-05-30 | 2001-05-30 | Produit comprenant du mikanolide, du dihydromikanolide ou un analogue de ceux-ci en association avec un autre agent anti-cancereux pour une utilisation therapeutique dans le traitement du cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL369148A1 true PL369148A1 (pl) | 2005-04-18 |
Family
ID=8863791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL02369148A PL369148A1 (pl) | 2001-05-30 | 2002-05-29 | Produkt zawierający mikanolid, dihydromikanolid lub ich analog w kombinacji z innym środkiem przeciwrakowym do stosowania terapeutycznego w leczeniu raka |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20040138245A1 (pl) |
| EP (1) | EP1438039A2 (pl) |
| JP (1) | JP2004533456A (pl) |
| KR (1) | KR20040025922A (pl) |
| CN (1) | CN1691941A (pl) |
| AR (1) | AR034059A1 (pl) |
| CA (1) | CA2448528A1 (pl) |
| CZ (1) | CZ20033549A3 (pl) |
| FR (1) | FR2825278A1 (pl) |
| HU (1) | HUP0400153A2 (pl) |
| PL (1) | PL369148A1 (pl) |
| RU (1) | RU2003137833A (pl) |
| WO (1) | WO2002096348A2 (pl) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2834289B1 (fr) * | 2001-12-27 | 2004-03-19 | Sod Conseils Rech Applic | Derives de benzothiazole-4,7-diones et benzooxazole-4,7- diones, leur preparation et leurs applications therapeutiques |
| CN100425600C (zh) * | 2001-12-27 | 2008-10-15 | 科学研究和应用咨询公司 | 苯并噻唑－和苯并唑－4,7－二酮衍生物及其作为cdc25磷酸酯酶抑制剂的用途 |
| FR2856688B1 (fr) * | 2003-06-25 | 2008-05-30 | Sod Conseils Rech Applic | PRODUIT COMPRENANT AU MOINS UN INHIBITEUR DE PHOSPHATASE CDc25 EN ASSOCIATION AVEC AU MOINS UN AUTRE AGENT ANTI-CANCEREUX |
| FR2856686A1 (fr) | 2003-06-25 | 2004-12-31 | Sod Conseils Rech Applic | Benzothiazole-4,7-diones et benzooxazole-4,7-diones substituees en position 5 ou 6 et leurs procedes de preparation |
| AR047969A1 (es) | 2004-02-25 | 2006-03-15 | Schering Corp | Pirazolotriazinas como inhibidores de quinasa |
| FR2879460B1 (fr) * | 2004-12-17 | 2007-02-23 | Sod Conseils Rech Applic | Associations anti-douleur comprenant un derive de dihydroimidazopyrazine |
| US7723336B2 (en) * | 2005-09-22 | 2010-05-25 | Bristol-Myers Squibb Company | Fused heterocyclic compounds useful as kinase modulators |
| TW200806284A (en) * | 2006-03-31 | 2008-02-01 | Alcon Mfg Ltd | Prenyltransferase inhibitors for ocular hypertension control and the treatment of glaucoma |
| WO2009100375A1 (en) | 2008-02-06 | 2009-08-13 | Bristol-Myers Squibb Company | Substituted imidazopyridazines useful as kinase inhibitors |
| AR077463A1 (es) | 2009-07-09 | 2011-08-31 | Irm Llc | Derivados de imidazo[1, 2 - a]pirazina y su uso en medicamentos para el tratamiento de enfermedades parasitarias |
| WO2011090738A2 (en) | 2009-12-29 | 2011-07-28 | Dana-Farber Cancer Institute, Inc. | Type ii raf kinase inhibitors |
| JP6854762B2 (ja) | 2014-12-23 | 2021-04-07 | ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド | サイクリン依存性キナーゼ７（ｃｄｋ７）の阻害剤 |
| USRE50776E1 (en) | 2015-03-27 | 2026-02-03 | Dana-Farber Cancer Institute, Inc. | Inhibitors of cyclin-dependent kinases |
| CN106317057B (zh) * | 2015-07-02 | 2019-02-01 | 北京桦冠医药科技有限公司 | 具有咪唑并吡嗪类衍生物，其制备及其在医药上的应用 |
| CN109790191B (zh) * | 2016-08-05 | 2022-04-08 | 香港大学 | 铂配合物及其使用方法 |
| CN110691597A (zh) | 2017-04-24 | 2020-01-14 | 诺华股份有限公司 | 2-氨基-1-(2-(4-氟苯基)-3-(4-氟苯基氨基)-8,8-二甲基-5,6-二氢咪唑并[1,2-a]吡嗪-7(8H)-基)乙酮及其组合的治疗方案 |
| EP3810132A4 (en) | 2018-06-25 | 2022-06-22 | Dana-Farber Cancer Institute, Inc. | TAIRE FAMILY KINASE INHIBITORS AND RELATED USES |
| CN111484503B (zh) * | 2020-01-10 | 2022-05-27 | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 一种薇甘菊内酯衍生物及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07267940A (ja) * | 1994-03-29 | 1995-10-17 | Ajinomoto Co Inc | 新規な１１員環化合物 |
| DE69623961T2 (de) * | 1995-06-21 | 2003-05-08 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.), Paris | Camptothecinanaloge, verfahren zur ihrer herstellung, ihre verwendungals arzneimittel und diese enthaltende pharmazeutische zusammenfassungen |
| CZ20021550A3 (cs) * | 1999-11-09 | 2003-02-12 | Societe De Conseils De Recherches Et D'application | Produkt zahrnující inhibitor transdukce signálů heterotrimerického G proteinu kombinovaný s jiným protirakovinným činidlem pro terapeutické použití v léčbě rakoviny |
| FR2801792B1 (fr) * | 1999-12-01 | 2003-04-18 | Sod Conseils Rech Applic | Un nouveau medicament, le dihydromikanolide, son obtention par extraction de la plante mikania micrantha et son utilisation comme agent anti-proliferatif |
-
2001
- 2001-05-30 FR FR0107104A patent/FR2825278A1/fr not_active Withdrawn
-
2002
- 2002-05-29 WO PCT/FR2002/001800 patent/WO2002096348A2/fr not_active Ceased
- 2002-05-29 CA CA002448528A patent/CA2448528A1/fr not_active Abandoned
- 2002-05-29 EP EP02738284A patent/EP1438039A2/fr not_active Withdrawn
- 2002-05-29 PL PL02369148A patent/PL369148A1/pl not_active Application Discontinuation
- 2002-05-29 HU HU0400153A patent/HUP0400153A2/hu unknown
- 2002-05-29 KR KR10-2003-7015600A patent/KR20040025922A/ko not_active Withdrawn
- 2002-05-29 JP JP2002592861A patent/JP2004533456A/ja not_active Abandoned
- 2002-05-29 CZ CZ20033549A patent/CZ20033549A3/cs unknown
- 2002-05-29 RU RU2003137833/15A patent/RU2003137833A/ru not_active Application Discontinuation
- 2002-05-29 US US10/478,387 patent/US20040138245A1/en not_active Abandoned
- 2002-05-29 CN CNA028125924A patent/CN1691941A/zh active Pending
- 2002-05-30 AR ARP020102025A patent/AR034059A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2825278A1 (fr) | 2002-12-06 |
| HUP0400153A2 (en) | 2007-07-30 |
| KR20040025922A (ko) | 2004-03-26 |
| WO2002096348A3 (fr) | 2004-05-06 |
| RU2003137833A (ru) | 2005-03-27 |
| US20040138245A1 (en) | 2004-07-15 |
| CA2448528A1 (fr) | 2002-12-05 |
| CN1691941A (zh) | 2005-11-02 |
| AR034059A1 (es) | 2004-01-21 |
| JP2004533456A (ja) | 2004-11-04 |
| EP1438039A2 (fr) | 2004-07-21 |
| WO2002096348A2 (fr) | 2002-12-05 |
| CZ20033549A3 (cs) | 2004-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |