PL373697A1 - Pochodne izochinoliny - Google Patents

Pochodne izochinoliny

Info

Publication number
PL373697A1
PL373697A1 PL03373697A PL37369703A PL373697A1 PL 373697 A1 PL373697 A1 PL 373697A1 PL 03373697 A PL03373697 A PL 03373697A PL 37369703 A PL37369703 A PL 37369703A PL 373697 A1 PL373697 A1 PL 373697A1
Authority
PL
Poland
Prior art keywords
isoquinoline derivatives
isoquinoline
derivatives
Prior art date
Application number
PL03373697A
Other languages
English (en)
Inventor
Andrea Cesura
Sarmiento Rosa Maria Rodriguez
Michelangelo Scalone
Andrew William Thomas
Rene Wyler
Original Assignee
F.Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F.Hoffmann-La Roche Ag filed Critical F.Hoffmann-La Roche Ag
Publication of PL373697A1 publication Critical patent/PL373697A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
PL03373697A 2002-04-26 2003-04-14 Pochodne izochinoliny PL373697A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02009253 2002-04-26

Publications (1)

Publication Number Publication Date
PL373697A1 true PL373697A1 (pl) 2005-09-05

Family

ID=29265896

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03373697A PL373697A1 (pl) 2002-04-26 2003-04-14 Pochodne izochinoliny

Country Status (30)

Country Link
US (1) US6818774B2 (pl)
EP (1) EP1501804B1 (pl)
JP (1) JP4322685B2 (pl)
KR (1) KR100681585B1 (pl)
CN (1) CN1310890C (pl)
AR (1) AR039651A1 (pl)
AT (1) ATE440821T1 (pl)
AU (1) AU2003227614B2 (pl)
BR (1) BR0309562A (pl)
CA (1) CA2483461C (pl)
DE (1) DE60328978D1 (pl)
DK (1) DK1501804T3 (pl)
ES (1) ES2329354T3 (pl)
GT (1) GT200300095A (pl)
HR (1) HRP20040952A2 (pl)
IL (1) IL164677A0 (pl)
MX (1) MXPA04010537A (pl)
MY (1) MY133527A (pl)
NO (1) NO20044571L (pl)
NZ (1) NZ535885A (pl)
PA (1) PA8572001A1 (pl)
PE (1) PE20040594A1 (pl)
PL (1) PL373697A1 (pl)
PT (1) PT1501804E (pl)
RU (1) RU2318812C2 (pl)
SI (1) SI1501804T1 (pl)
TW (1) TWI278451B (pl)
UY (1) UY27786A1 (pl)
WO (1) WO2003091219A1 (pl)
ZA (1) ZA200408281B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0410746A (pt) * 2003-05-19 2006-06-27 Irm Llc compostos e composições imunossupressoras
EP1638551B1 (en) * 2003-05-19 2011-12-21 Irm Llc Immunosuppressant compounds and compositions
MY150088A (en) 2003-05-19 2013-11-29 Irm Llc Immunosuppressant compounds and compositions
US7825109B2 (en) 2003-08-29 2010-11-02 Ono Pharmaceutical Co., Ltd. Compound capable of binding S1P receptor and pharmaceutical use thereof
BRPI0413923A (pt) * 2003-08-29 2006-11-07 Ono Pharmaceutical Co composto capaz de ligar o receptor de s1p e uso farmacêutico do mesmo
WO2005039591A1 (en) * 2003-10-23 2005-05-06 F. Hoffmann-La Roche Ag Benzazepine derivatives as mao-b inhibitors
US7763638B2 (en) 2004-03-01 2010-07-27 Actelion Pharmaceuticals Ltd. Substituted 1,2,3,4-tetrahydroisoquinoline derivatives
EP2371811B1 (en) 2004-12-13 2014-10-08 Ono Pharmaceutical Co., Ltd. Azetidinecarboxylic acid derivative and medicinal use thereof
JP4934055B2 (ja) * 2005-01-28 2012-05-16 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト イソクロマンおよびその誘導体の製造方法
CN101128189A (zh) 2005-02-25 2008-02-20 弗·哈夫曼-拉罗切有限公司 药物物质分散性改善的片剂
JP5271087B2 (ja) * 2005-12-22 2013-08-21 ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー カルシウム及び／又はナトリウムチャネル調節物質としての２−フェニルエチルアミノ誘導体
CA2644010A1 (en) * 2006-03-15 2007-09-20 Actelion Pharmaceuticals Ltd Tetrahydroisoquinoline derivatives to enhance memory function
CN101432285A (zh) 2006-04-26 2009-05-13 埃科特莱茵药品有限公司 作为食欲素受体拮抗剂的吡唑并-四氢吡啶衍生物
KR101220182B1 (ko) * 2009-02-25 2013-01-11 에스케이바이오팜 주식회사 치환된 아졸 유도체 화합물, 이를 포함하는 약제학적 조성물 및 이를 이용한 파킨슨씨 병 치료방법
CN105315204B (zh) * 2014-07-04 2018-02-09 中南大学 7‑氨基‑1,4‑二氢异喹啉‑3(2h)‑酮衍生物及其合成方法和用途
CN105461626B (zh) * 2015-12-17 2018-05-08 浙江工业大学 芳环或稠杂环联3,4-二氢异喹啉类共轭结构化合物及其应用
CN105585527B (zh) * 2015-12-17 2018-06-26 浙江工业大学 2-(3,4-二氢异喹啉-1(2h)-亚基)乙腈类化合物及其应用
CN110461829B (zh) * 2017-03-27 2023-02-28 百时美施贵宝公司 作为免疫调节剂的取代的异喹啉衍生物
JP7720847B2 (ja) * 2019-12-18 2025-08-08 シーエイチディーアイ ファウンデーション，インコーポレーテッド ハンチンチンタンパク質をイメージングするための化合物及びプローブ
CN114591238B (zh) * 2022-03-25 2022-11-15 邦恩泰(山东)生物医药科技集团股份有限公司 一种异喹啉类药物中间体的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6137002A (en) * 1993-07-22 2000-10-24 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists
IL110172A (en) * 1993-07-22 2001-10-31 Lilly Co Eli Bicyclic compounds and pharmaceutical compositions containing them
US6448269B1 (en) * 1993-07-22 2002-09-10 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists
US5731324A (en) * 1993-07-22 1998-03-24 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists
US5679715A (en) 1995-06-07 1997-10-21 Harris; Richard Y. Method for treating multiple sclerosis
WO1997033572A1 (en) 1996-03-15 1997-09-18 Somerset Pharmaceuticals, Inc. Method for preventing and treating peripheral neurophathy by administering selegiline
WO2001034172A2 (en) 1999-11-05 2001-05-17 Vela Pharmaceuticals Inc. Methods and compositions for treating reward deficiency syndrome

Also Published As

Publication number Publication date
JP4322685B2 (ja) 2009-09-02
BR0309562A (pt) 2005-02-15
PT1501804E (pt) 2009-10-29
GT200300095A (es) 2004-01-15
TW200307670A (en) 2003-12-16
TWI278451B (en) 2007-04-11
ZA200408281B (en) 2005-10-14
IL164677A0 (en) 2005-12-18
AU2003227614A1 (en) 2003-11-10
AR039651A1 (es) 2005-03-02
MXPA04010537A (es) 2005-01-25
EP1501804A1 (en) 2005-02-02
MY133527A (en) 2007-11-30
US20030225122A1 (en) 2003-12-04
ATE440821T1 (de) 2009-09-15
RU2318812C2 (ru) 2008-03-10
PA8572001A1 (es) 2003-12-10
UY27786A1 (es) 2003-10-31
EP1501804B1 (en) 2009-08-26
HK1080836A1 (en) 2006-05-04
US6818774B2 (en) 2004-11-16
NO20044571L (no) 2004-10-22
CA2483461C (en) 2010-12-21
NZ535885A (en) 2007-05-31
CA2483461A1 (en) 2003-11-06
HRP20040952A2 (en) 2005-06-30
KR20040104628A (ko) 2004-12-10
RU2004134575A (ru) 2005-07-20
DK1501804T3 (da) 2009-10-12
CN1310890C (zh) 2007-04-18
JP2005533761A (ja) 2005-11-10
CN1649844A (zh) 2005-08-03
ES2329354T3 (es) 2009-11-25
SI1501804T1 (sl) 2009-12-31
WO2003091219A1 (en) 2003-11-06
KR100681585B1 (ko) 2007-02-09
AU2003227614B2 (en) 2008-06-26
DE60328978D1 (de) 2009-10-08
PE20040594A1 (es) 2004-08-30

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Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)