PL373697A1 - Pochodne izochinoliny - Google Patents

Pochodne izochinoliny

Info

Publication number: PL373697A1
Authority: PL; Poland
Prior art keywords: isoquinoline derivatives; isoquinoline; derivatives
Prior art date: 2002-04-26

Application number

PL03373697A

Other languages

English (en)

Inventor

Andrea Cesura

Sarmiento Rosa Maria Rodriguez

Michelangelo Scalone

Andrew William Thomas

Rene Wyler

Original Assignee

F.Hoffmann-La Roche Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-26

Filing date

2003-04-14

Publication date

2005-09-05

2003-04-14 Application filed by F.Hoffmann-La Roche Ag filed Critical F.Hoffmann-La Roche Ag

2005-09-05 Publication of PL373697A1 publication Critical patent/PL373697A1/pl

Links

125000002183 isoquinolinyl group Chemical class C1(=NC=CC2=CC=CC=C12)* 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)

PL03373697A 2002-04-26 2003-04-14 Pochodne izochinoliny PL373697A1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02009253		2002-04-26

Publications (1)

Publication Number	Publication Date
PL373697A1 true PL373697A1 (pl)	2005-09-05

Family

ID=29265896

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL03373697A PL373697A1 (pl)	2002-04-26	2003-04-14	Pochodne izochinoliny

Country Status (30)

Country	Link
US (1)	US6818774B2 (pl)
EP (1)	EP1501804B1 (pl)
JP (1)	JP4322685B2 (pl)
KR (1)	KR100681585B1 (pl)
CN (1)	CN1310890C (pl)
AR (1)	AR039651A1 (pl)
AT (1)	ATE440821T1 (pl)
AU (1)	AU2003227614B2 (pl)
BR (1)	BR0309562A (pl)
CA (1)	CA2483461C (pl)
DE (1)	DE60328978D1 (pl)
DK (1)	DK1501804T3 (pl)
ES (1)	ES2329354T3 (pl)
GT (1)	GT200300095A (pl)
HR (1)	HRP20040952A2 (pl)
IL (1)	IL164677A0 (pl)
MX (1)	MXPA04010537A (pl)
MY (1)	MY133527A (pl)
NO (1)	NO20044571L (pl)
NZ (1)	NZ535885A (pl)
PA (1)	PA8572001A1 (pl)
PE (1)	PE20040594A1 (pl)
PL (1)	PL373697A1 (pl)
PT (1)	PT1501804E (pl)
RU (1)	RU2318812C2 (pl)
SI (1)	SI1501804T1 (pl)
TW (1)	TWI278451B (pl)
UY (1)	UY27786A1 (pl)
WO (1)	WO2003091219A1 (pl)
ZA (1)	ZA200408281B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY150088A (en)	2003-05-19	2013-11-29	Irm Llc	Immunosuppressant compounds and compositions
MXPA05012459A (es) *	2003-05-19	2006-02-22	Irm Llc	Compuestos y composiciones inmunosupresoras.
EP1644367B1 (en) *	2003-05-19	2015-10-14	Novartis AG	Immunosuppressant compounds and compositions
US7825109B2 (en)	2003-08-29	2010-11-02	Ono Pharmaceutical Co., Ltd.	Compound capable of binding S1P receptor and pharmaceutical use thereof
KR20110140139A (ko) *	2003-08-29	2011-12-30	오노 야꾸힝 고교 가부시키가이샤	Ｓ１ｐ 수용체 결합능을 갖는 화합물 및 그 의약 용도
AU2004283452A1 (en) *	2003-10-23	2005-05-06	F. Hoffmann-La Roche Ag	Benzazepine derivatives as MAO-B inhibitors
CA2557163C (en)	2004-03-01	2011-08-16	Idorsia Pharmaceuticals Ltd	Substituted 1,2,3,4-tetrahydroisoquinoline derivatives
BRPI0519012A2 (pt)	2004-12-13	2008-12-23	Ono Pharmaceutical Co	derivado do Ácido aminocarboxÍlico e seu uso medicinal
EP1844033B1 (de) *	2005-01-28	2011-07-27	Boehringer Ingelheim Pharma GmbH & Co. KG	Verfahren zur herstellung von isochroman und derivaten davon
KR20070094666A (ko)	2005-02-25	2007-09-20	에프. 호프만-라 로슈 아게	약제 물질 분산성이 향상된 정제
EP1963280B1 (en)	2005-12-22	2015-10-28	Newron Pharmaceuticals S.p.A.	2-phenylethylamino derivatives as calcium and/or sodium channel modulators
AU2007226203A1 (en) *	2006-03-15	2007-09-20	Actelion Pharmaceuticals Ltd	Tetrahydroisoquinoline derivatives to enhance memory function
DE602007012072D1 (de)	2006-04-26	2011-03-03	Actelion Pharmaceuticals Ltd	Orantagonisten
KR101220182B1 (ko) *	2009-02-25	2013-01-11	에스케이바이오팜 주식회사	치환된 아졸 유도체 화합물, 이를 포함하는 약제학적 조성물 및 이를 이용한 파킨슨씨 병 치료방법
CN105315204B (zh) *	2014-07-04	2018-02-09	中南大学	7‑氨基‑1,4‑二氢异喹啉‑3(2h)‑酮衍生物及其合成方法和用途
CN105461626B (zh) *	2015-12-17	2018-05-08	浙江工业大学	芳环或稠杂环联3,4-二氢异喹啉类共轭结构化合物及其应用
CN105585527B (zh) *	2015-12-17	2018-06-26	浙江工业大学	2-(3,4-二氢异喹啉-1(2h)-亚基)乙腈类化合物及其应用
CN110461829B (zh) *	2017-03-27	2023-02-28	百时美施贵宝公司	作为免疫调节剂的取代的异喹啉衍生物
ES3029867T3 (en) *	2019-12-18	2025-06-25	Chdi Foundation Inc	Compounds and probes for imaging huntingtin protein
CN114591238B (zh) *	2022-03-25	2022-11-15	邦恩泰(山东)生物医药科技集团股份有限公司	一种异喹啉类药物中间体的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6448269B1 (en) *	1993-07-22	2002-09-10	Eli Lilly And Company	Glycoprotein IIb/IIIa antagonists
US6137002A (en) *	1993-07-22	2000-10-24	Eli Lilly And Company	Glycoprotein IIb/IIIa antagonists
US5731324A (en) *	1993-07-22	1998-03-24	Eli Lilly And Company	Glycoprotein IIb/IIIa antagonists
IL110172A (en) *	1993-07-22	2001-10-31	Lilly Co Eli	Bicyclic compounds and pharmaceutical compositions containing them
US5679715A (en)	1995-06-07	1997-10-21	Harris; Richard Y.	Method for treating multiple sclerosis
EP0906090A1 (en)	1996-03-15	1999-04-07	Somerset Pharmaceuticals, Inc.	Method for preventing and treating peripheral neurophathy by administering selegiline
AU1359801A (en)	1999-11-05	2001-06-06	Vela Pharmaceuticals Inc.	Methods and compositions for treating reward deficiency syndrome

2003
- 2003-04-14 DK DK03725018T patent/DK1501804T3/da active
- 2003-04-14 AU AU2003227614A patent/AU2003227614B2/en not_active Ceased
- 2003-04-14 NZ NZ535885A patent/NZ535885A/en not_active IP Right Cessation
- 2003-04-14 EP EP03725018A patent/EP1501804B1/en not_active Expired - Lifetime
- 2003-04-14 MX MXPA04010537A patent/MXPA04010537A/es active IP Right Grant
- 2003-04-14 AT AT03725018T patent/ATE440821T1/de not_active IP Right Cessation
- 2003-04-14 ES ES03725018T patent/ES2329354T3/es not_active Expired - Lifetime
- 2003-04-14 CA CA2483461A patent/CA2483461C/en not_active Expired - Fee Related
- 2003-04-14 DE DE60328978T patent/DE60328978D1/de not_active Expired - Lifetime
- 2003-04-14 BR BR0309562-2A patent/BR0309562A/pt not_active IP Right Cessation
- 2003-04-14 CN CNB038093766A patent/CN1310890C/zh not_active Expired - Fee Related
- 2003-04-14 WO PCT/EP2003/003845 patent/WO2003091219A1/en not_active Ceased
- 2003-04-14 JP JP2003587782A patent/JP4322685B2/ja not_active Expired - Fee Related
- 2003-04-14 KR KR1020047017185A patent/KR100681585B1/ko not_active Expired - Fee Related
- 2003-04-14 PT PT03725018T patent/PT1501804E/pt unknown
- 2003-04-14 SI SI200331658T patent/SI1501804T1/sl unknown
- 2003-04-14 HR HR20040952A patent/HRP20040952A2/hr not_active Application Discontinuation
- 2003-04-14 RU RU2004134575/04A patent/RU2318812C2/ru not_active IP Right Cessation
- 2003-04-14 PL PL03373697A patent/PL373697A1/pl unknown
- 2003-04-16 US US10/417,378 patent/US6818774B2/en not_active Expired - Fee Related
- 2003-04-23 TW TW092109478A patent/TWI278451B/zh not_active IP Right Cessation
- 2003-04-23 PA PA20038572001A patent/PA8572001A1/es unknown
- 2003-04-24 AR ARP030101412A patent/AR039651A1/es unknown
- 2003-04-24 GT GT200300095A patent/GT200300095A/es unknown
- 2003-04-24 PE PE2003000408A patent/PE20040594A1/es not_active Application Discontinuation
- 2003-04-25 MY MYPI20031578A patent/MY133527A/en unknown
- 2003-04-28 UY UY27786A patent/UY27786A1/es not_active Application Discontinuation
2004
- 2004-10-13 ZA ZA200408281A patent/ZA200408281B/xx unknown
- 2004-10-18 IL IL16467704A patent/IL164677A0/xx not_active IP Right Cessation
- 2004-10-22 NO NO20044571A patent/NO20044571L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
MY133527A (en)	2007-11-30
PA8572001A1 (es)	2003-12-10
TWI278451B (en)	2007-04-11
EP1501804A1 (en)	2005-02-02
ATE440821T1 (de)	2009-09-15
ES2329354T3 (es)	2009-11-25
AU2003227614B2 (en)	2008-06-26
NZ535885A (en)	2007-05-31
CN1649844A (zh)	2005-08-03
NO20044571L (no)	2004-10-22
KR100681585B1 (ko)	2007-02-09
US20030225122A1 (en)	2003-12-04
AR039651A1 (es)	2005-03-02
BR0309562A (pt)	2005-02-15
US6818774B2 (en)	2004-11-16
DE60328978D1 (de)	2009-10-08
CN1310890C (zh)	2007-04-18
TW200307670A (en)	2003-12-16
HRP20040952A2 (en)	2005-06-30
PT1501804E (pt)	2009-10-29
UY27786A1 (es)	2003-10-31
SI1501804T1 (sl)	2009-12-31
DK1501804T3 (da)	2009-10-12
RU2318812C2 (ru)	2008-03-10
ZA200408281B (en)	2005-10-14
EP1501804B1 (en)	2009-08-26
GT200300095A (es)	2004-01-15
CA2483461C (en)	2010-12-21
PE20040594A1 (es)	2004-08-30
JP4322685B2 (ja)	2009-09-02
JP2005533761A (ja)	2005-11-10
MXPA04010537A (es)	2005-01-25
IL164677A0 (en)	2005-12-18
WO2003091219A1 (en)	2003-11-06
HK1080836A1 (en)	2006-05-04
CA2483461A1 (en)	2003-11-06
RU2004134575A (ru)	2005-07-20
KR20040104628A (ko)	2004-12-10
AU2003227614A1 (en)	2003-11-10

Legal Events

Date	Code	Title	Description
2012-03-30	DISC	Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
AP1850A (en)	2008-05-26	Spiroindolineplperidine derivatives
EG24050A (en)	2008-04-13	Heterocylocarboxamide derivatives
PL374718A1 (pl)	2005-10-31	Azolidynono-winylowe pochodne skondensowanego benzenu
IL166121A0 (en)	2006-01-15	Indole-3-sulphur derivatives
EP1522540A4 (en)	2011-08-10	AZAARENE DERIVATIVES
PL376475A1 (pl)	2005-12-27	Pochodne N-podstawionej 2-oksodihydropirydyny
IL164324A0 (en)	2005-12-18	Quinolinone derivatives
GB0317665D0 (en)	2003-09-03	Qinazoline derivatives
PL1682493T3 (pl)	2009-06-30	Pochodne amidoacetonitrylu
PL1606277T3 (pl)	2008-10-31	Pochodne imidazol-4-iloetynylo-pirydyny
IL166426A0 (en)	2006-01-15	N-biarylmethyl aminocycloalkanecarboxamide derivatives
AU2003227712A1 (en)	2003-12-02	Tetrahydroisoquinoline derivatives
PL373697A1 (pl)	2005-09-05	Pochodne izochinoliny
PL376997A1 (pl)	2006-01-23	Pochodne tetrahydrochinoliny
IL165572A0 (en)	2006-01-15	1-Ä(indoÜ-3-yl)carbonylÜpiperazine derivatives
IL175189A0 (en)	2006-09-05	N-thiazol-2-yl-benzamide derivatives
PL377318A1 (pl)	2006-01-23	Pochodne tetrahydrochinoliny
PL371216A1 (pl)	2005-06-13	Pochodne izochinoliny
AU2003222659A8 (en)	2003-11-03	23-o-substituted 5-o-mycaminosyltylonide derivatives
EG24415A (en)	2009-05-25	Quinoline derivatives
EP1531854A4 (en)	2006-06-28	O-DERIVATED NOCATHIACIN DERIVATIVES
GB0319793D0 (en)	2003-09-24	Pyridinylmorpholine derivatives
GB0213488D0 (en)	2002-07-24	2-Naphthamide derivatives
AU2003243397A8 (en)	2003-12-19	Homo-camptothecin derivatives
AU2003290095A8 (en)	2004-07-14	Quinolizidine derivatives