PL373845A1 - Krystaliczne formy olanzapiny i sposoby ich otrzymywania - Google Patents

Krystaliczne formy olanzapiny i sposoby ich otrzymywania

Info

Publication number
PL373845A1
PL373845A1 PL03373845A PL37384503A PL373845A1 PL 373845 A1 PL373845 A1 PL 373845A1 PL 03373845 A PL03373845 A PL 03373845A PL 37384503 A PL37384503 A PL 37384503A PL 373845 A1 PL373845 A1 PL 373845A1
Authority
PL
Poland
Prior art keywords
olanzapine
processes
preparation
crystal forms
crystal
Prior art date
Application number
PL03373845A
Other languages
English (en)
Other versions
PL217081B1 (pl
Inventor
Jordan Berta Kotar
Franc Vrecer
Marija Grcman
Original Assignee
Krka, D.D, Novo Mesto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krka, D.D, Novo Mesto filed Critical Krka, D.D, Novo Mesto
Publication of PL373845A1 publication Critical patent/PL373845A1/pl
Publication of PL217081B1 publication Critical patent/PL217081B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL373845A 2002-07-15 2003-07-14 Sposób otrzymywania formy I olanzapiny, solwat olanzapiny z 2-propanolem oraz solwaty olanzapiny z chlorkiem metylenu PL217081B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SI200200175A SI21270A (sl) 2002-07-15 2002-07-15 Kristalne oblike olanzapina in postopki za njihovo pripravo

Publications (2)

Publication Number Publication Date
PL373845A1 true PL373845A1 (pl) 2005-09-19
PL217081B1 PL217081B1 (pl) 2014-06-30

Family

ID=30113490

Family Applications (1)

Application Number Title Priority Date Filing Date
PL373845A PL217081B1 (pl) 2002-07-15 2003-07-14 Sposób otrzymywania formy I olanzapiny, solwat olanzapiny z 2-propanolem oraz solwaty olanzapiny z chlorkiem metylenu

Country Status (12)

Country Link
US (1) US7745429B2 (pl)
EP (1) EP1551414B1 (pl)
AU (1) AU2003256242A1 (pl)
CA (1) CA2493370C (pl)
EA (1) EA008055B1 (pl)
HR (1) HRP20050039B1 (pl)
NO (1) NO20050720L (pl)
PL (1) PL217081B1 (pl)
RS (1) RS53474B (pl)
SI (2) SI21270A (pl)
UA (1) UA83633C2 (pl)
WO (1) WO2004006933A2 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL202856B1 (pl) * 2002-12-20 2009-07-31 Adamed Spo & Lstrok Ka Z Ogran Sposób otrzymywania farmaceutycznie czystej polimorficznej postaci I olanzapiny
WO2004058773A1 (en) * 2002-12-24 2004-07-15 Teva Pharmaceutical Industries Ltd. Novel crystal forms of olanzapine, methods for their preparation and method for the preparation of known olanzapine crystal forms
EP1709053B1 (en) 2004-01-27 2011-04-06 Synthon B.V. Stable salts of olanzapine
WO2005070937A1 (en) * 2004-01-27 2005-08-04 Synthon B.V. A process for making olanzapine in a polymorph form i
ATE517109T1 (de) * 2004-03-08 2011-08-15 Krka Tovarna Zdravil D D Novo Mesto Isopropanol-wasser-solvat von olanzapin
ES2253091B1 (es) * 2004-07-27 2007-02-01 Inke, S.A. Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
GB0522473D0 (en) 2005-11-03 2005-12-14 Actavis Group A pharmaceutical formulation
US7834176B2 (en) 2006-01-26 2010-11-16 Sandoz Ag Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU629879A3 (ru) 1974-11-26 1978-10-25 Лилли Индастриз Лимитед, (Фирма) Способ получени тиено(1,5) бензодиазепинов или их солей
US5229382A (en) * 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
EG24221A (en) * 1995-03-24 2008-11-10 Lilly Co Eli Process for preparing olanzapine
EG23659A (en) 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
CR5278A (es) * 1995-03-24 1996-07-04 Lilly Co Eli Formulacion oral de 2-metil-tieno-benzodiacepina
US5631250A (en) * 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
US5776928A (en) * 1995-04-21 1998-07-07 Eli Lilly And Company Method for treating dyskinesias with olanzapine
US6506746B2 (en) * 1995-05-30 2003-01-14 Eli Lilly And Company Method for treating cognitive dysfunction
ZA978515B (en) 1996-09-23 1999-03-23 Lilly Co Eli Intermediates and process for preparing olanzapine
HU226167B1 (hu) 1996-09-23 2008-05-28 Lilly Co Eli Olanzapin-dihidrát D, elõállítása és az azt tartalmazó gyógyszerkészítmények
JP2001517684A (ja) * 1997-09-30 2001-10-09 イーライ・リリー・アンド・カンパニー 性機能不全を処置するための方法
CA2395774C (en) * 1999-12-28 2009-09-15 Cipla Limited New polymorphic forms of olanzapine
IL154688A0 (en) 2000-08-31 2003-09-17 Reddys Lab Ltd Dr Hydrates of olanzapine and processes for the preparation thereof

Also Published As

Publication number Publication date
EA200500188A1 (ru) 2005-06-30
HRP20050039A2 (en) 2005-08-31
HRP20050039B1 (hr) 2014-10-10
WO2004006933A3 (en) 2004-04-01
EP1551414B1 (en) 2013-11-27
EA008055B1 (ru) 2007-02-27
RS20050023A (sr) 2007-06-04
SI1551414T1 (sl) 2014-04-30
US7745429B2 (en) 2010-06-29
SI21270A (sl) 2004-02-29
PL217081B1 (pl) 2014-06-30
AU2003256242A1 (en) 2004-02-02
CA2493370A1 (en) 2004-01-22
UA83633C2 (ru) 2008-08-11
WO2004006933A2 (en) 2004-01-22
EP1551414A2 (en) 2005-07-13
CA2493370C (en) 2009-09-29
RS53474B (sr) 2014-12-31
US20060040920A1 (en) 2006-02-23
NO20050720L (no) 2005-02-10

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