PL373873A1 - Sposób wytwarzania związków inkluzyjnych piroksikamu z beta-cyklodekstryną - Google Patents

Sposób wytwarzania związków inkluzyjnych piroksikamu z beta-cyklodekstryną

Info

Publication number
PL373873A1
PL373873A1 PL03373873A PL37387303A PL373873A1 PL 373873 A1 PL373873 A1 PL 373873A1 PL 03373873 A PL03373873 A PL 03373873A PL 37387303 A PL37387303 A PL 37387303A PL 373873 A1 PL373873 A1 PL 373873A1
Authority
PL
Poland
Prior art keywords
piroxicam
beta
preparation
inclusion compounds
cyclodextrin inclusion
Prior art date
Application number
PL03373873A
Other languages
English (en)
Other versions
PL218414B1 (pl
Inventor
Andrea Capocchi
Original Assignee
Chiesi Farmaceutici S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici S.P.A. filed Critical Chiesi Farmaceutici S.P.A.
Publication of PL373873A1 publication Critical patent/PL373873A1/pl
Publication of PL218414B1 publication Critical patent/PL218414B1/pl

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL373873A 2002-06-17 2003-06-12 Sposób wytwarzania związków inkluzyjnych piroksykamu z ß- cyklodekstryną PL218414B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02013251A EP1374906B1 (en) 2002-06-17 2002-06-17 A process for the preparation of piroxicam: beta-cyclodextrin inclusion compounds

Publications (2)

Publication Number Publication Date
PL373873A1 true PL373873A1 (pl) 2005-09-19
PL218414B1 PL218414B1 (pl) 2014-12-31

Family

ID=29716770

Family Applications (1)

Application Number Title Priority Date Filing Date
PL373873A PL218414B1 (pl) 2002-06-17 2003-06-12 Sposób wytwarzania związków inkluzyjnych piroksykamu z ß- cyklodekstryną

Country Status (26)

Country Link
US (1) US7700579B2 (pl)
EP (2) EP1374906B1 (pl)
KR (1) KR101079484B1 (pl)
CN (1) CN100352444C (pl)
AT (1) ATE359827T1 (pl)
AU (1) AU2003245931A1 (pl)
CA (1) CA2489708A1 (pl)
CY (1) CY1107693T1 (pl)
DE (1) DE60219609T2 (pl)
ES (1) ES2286177T3 (pl)
HR (1) HRP20041192B1 (pl)
IL (1) IL165797A0 (pl)
JO (1) JO2533B1 (pl)
MA (1) MA27367A1 (pl)
MX (1) MXPA04012502A (pl)
MY (1) MY134691A (pl)
NO (1) NO332262B1 (pl)
PL (1) PL218414B1 (pl)
PT (1) PT1374906E (pl)
RU (1) RU2316350C2 (pl)
SA (1) SA03240220B1 (pl)
SI (1) SI1374906T1 (pl)
TN (1) TNSN04245A1 (pl)
TW (1) TWI341731B (pl)
WO (1) WO2003105906A1 (pl)
ZA (1) ZA200410142B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2260871B1 (fr) 2004-04-01 2013-05-15 Pierre Fabre Medicament Complexes d'inclusions comprenant du piroxicam, une cyclodextrine et l'arginine
FR2868315B1 (fr) * 2004-04-01 2006-07-14 Pierre Fabre Medicament Sa Procede de preparation d'un compose d'inclusion soluble de substances actives dans une molecule hote avec l'aide d'un agent d'interaction par fluide supercritique
FR2876911B1 (fr) * 2004-10-21 2007-04-13 Pierre Fabre Medicament Sa Complexe comprenant du piroxicam, une cyclodextrine et de l'arginine
CN101002782B (zh) * 2007-01-10 2010-05-19 南京师范大学 含有头孢呋辛酯环糊精包合物的药物组合物及其制备方法
CN101264087B (zh) * 2007-03-14 2010-10-27 南京师范大学 含有头孢泊肟酯环糊精包合物的药物组合物及其制备方法
EP3459533A1 (en) 2010-08-04 2019-03-27 Grünenthal GmbH Pharmaceutical dosage form comprising 6'-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine for the treatment of nociceptive pain
WO2013004462A1 (en) 2011-07-01 2013-01-10 Fondazione Istituto Insubrico Di Ricerca Per La Vita A complex of amorphous tomoxiprole and cyclodextrin with fast dissolution rate and process for the preparation thereof
US20130310435A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol
US9308196B2 (en) * 2012-05-18 2016-04-12 Gruenenthal Gmbh Pharmaceutical composition comprising (1 r,4r) -6'-fluoro-N ,N-dimethyl-4-phenyl-4',9'-d ihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam
US9855286B2 (en) 2012-05-18 2018-01-02 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-di methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component
US8912226B2 (en) 2012-05-18 2014-12-16 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r) -6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a NSAR
US9320729B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative
US20130310385A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196033B (it) * 1984-02-22 1988-11-10 Chiesi Farma Spa Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche
IT1204725B (it) * 1987-06-17 1989-03-10 Edmond Pharma Srl Complessi di inclusione del dipiridamolo con ciclodestrine
WO1991013100A1 (en) * 1990-03-02 1991-09-05 Australian Commercial Research & Development Limited Cyclodextrin compositions and methods for pharmaceutical and industrial applications
US5164379A (en) * 1991-07-15 1992-11-17 Bristol-Myers Company Sucralfate/cyclodextrin complexes
IT1269578B (it) * 1994-04-22 1997-04-08 Chiesi Farma Spa Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo acido, una ciclodestrina e una base.
DE19922572A1 (de) * 1999-05-17 2000-11-23 Bayer Ag Verfahren zur Reinigung von organischen Isocyanaten, die so gereinigten organischen Isocyanate und ihre Verwendung

Also Published As

Publication number Publication date
HK1080720A1 (en) 2006-05-04
NO20040601L (no) 2004-02-10
EP1513556A1 (en) 2005-03-16
RU2004136988A (ru) 2005-06-10
HRP20041192A2 (en) 2005-08-31
EP1374906B1 (en) 2007-04-18
NO332262B1 (no) 2012-08-13
TWI341731B (en) 2011-05-11
EP1374906A1 (en) 2004-01-02
KR101079484B1 (ko) 2011-11-03
MY134691A (en) 2007-12-31
ES2286177T3 (es) 2007-12-01
DE60219609D1 (de) 2007-05-31
MXPA04012502A (es) 2005-02-24
PT1374906E (pt) 2007-07-24
TW200400043A (en) 2004-01-01
TNSN04245A1 (en) 2007-03-12
ZA200410142B (en) 2006-02-22
US20060135473A1 (en) 2006-06-22
DE60219609T2 (de) 2008-01-03
CY1107693T1 (el) 2013-04-18
EP1513556B1 (en) 2008-08-13
SA03240220B1 (ar) 2007-07-31
WO2003105906A1 (en) 2003-12-24
JO2533B1 (en) 2010-09-05
AU2003245931A1 (en) 2003-12-31
US7700579B2 (en) 2010-04-20
WO2003105906A8 (en) 2004-03-04
PL218414B1 (pl) 2014-12-31
CN1671419A (zh) 2005-09-21
ATE359827T1 (de) 2007-05-15
MA27367A1 (fr) 2005-06-01
RU2316350C2 (ru) 2008-02-10
SI1374906T1 (sl) 2007-10-31
CA2489708A1 (en) 2003-12-24
KR20050008642A (ko) 2005-01-21
CN100352444C (zh) 2007-12-05
IL165797A0 (en) 2006-01-15
HRP20041192B1 (hr) 2013-09-30

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