PL376683A1 - Podstawione indolopirydyny jako związki przeciwinfekcyjne - Google Patents

Podstawione indolopirydyny jako związki przeciwinfekcyjne

Info

Publication number
PL376683A1
PL376683A1 PL376683A PL37668303A PL376683A1 PL 376683 A1 PL376683 A1 PL 376683A1 PL 376683 A PL376683 A PL 376683A PL 37668303 A PL37668303 A PL 37668303A PL 376683 A1 PL376683 A1 PL 376683A1
Authority
PL
Poland
Prior art keywords
infective compounds
indolepyridinium
substituted
substituted indolepyridinium
infective
Prior art date
Application number
PL376683A
Other languages
English (en)
Inventor
Bart Rudolf Romanie Kesteleyn
De Vreken Wim Van
Natalie Maria Francisca Kindermans
Maxime Francis Jean-Marie Ghislain Canard
Kurt Hertogs
Eva Bettens
Vroey Veronique Corine Paul De
Dirk Edward Desire Jochmans
Original Assignee
Tibotec Pharmaceuticals Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharmaceuticals Ltd. filed Critical Tibotec Pharmaceuticals Ltd.
Publication of PL376683A1 publication Critical patent/PL376683A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL376683A 2002-11-15 2003-11-14 Podstawione indolopirydyny jako związki przeciwinfekcyjne PL376683A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02079783 2002-11-15
US43495002P 2002-12-20 2002-12-20

Publications (1)

Publication Number Publication Date
PL376683A1 true PL376683A1 (pl) 2006-01-09

Family

ID=32327852

Family Applications (1)

Application Number Title Priority Date Filing Date
PL376683A PL376683A1 (pl) 2002-11-15 2003-11-14 Podstawione indolopirydyny jako związki przeciwinfekcyjne

Country Status (16)

Country Link
US (2) US7608726B2 (pl)
EP (1) EP1594870B1 (pl)
JP (1) JP2006508145A (pl)
KR (1) KR20050084621A (pl)
CN (1) CN100457754C (pl)
AP (1) AP1927A (pl)
AU (1) AU2003296760B2 (pl)
BR (1) BR0316209A (pl)
CA (1) CA2506316A1 (pl)
EA (1) EA009871B1 (pl)
HR (1) HRP20050543A2 (pl)
MX (1) MXPA05005146A (pl)
NO (1) NO20052884L (pl)
NZ (1) NZ540321A (pl)
PL (1) PL376683A1 (pl)
WO (1) WO2004046143A1 (pl)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
EA200602136A1 (ru) * 2004-05-17 2007-04-27 Тиботек Фармасьютикалз Лтд. Комбинации замещенных 1-фенил-1,5-дигидропиридо[3,2-b] индол-2-онов и других ингибиторов вич
TW200607502A (en) * 2004-05-17 2006-03-01 Tibotec Pharm Ltd 6, 7, 8, 9-substituted 1-phenyl-1, 5-dihydro-pyrido[3, 2-b]indol-2-ones
KR20070015608A (ko) 2004-05-17 2007-02-05 티보텍 파마슈티칼즈 리미티드 1-헤테로사이클일-1,5-디히드로-피리도[3,2-ｂ]인돌-2-온
MXPA06013312A (es) * 2004-05-17 2007-02-02 Tibotec Pharm Ltd 1-fenil-1,5-dihidro-pirido[3,2-b]indol-2-onas 5-sustituidas y analogos como antivirales.
MXPA06013315A (es) 2004-05-17 2007-02-02 Tibotec Pharm Ltd 1,5-dihidro-pirido[3,2-b]indol-2-onas 4-sustituidas.
ATE542802T1 (de) 2004-09-30 2012-02-15 Tibotec Pharm Ltd Hiv-inhibierende 5-substituierte pyrimidine
US8575342B2 (en) 2004-09-30 2013-11-05 Tibotech Pharmaceuticals Ltd. HIV inhibiting 5-heterocyclyl pyrimidines
TW200637862A (en) 2005-01-10 2006-11-01 Tibotec Pharm Ltd 1,5,6-substituted-2-oxo-3-cyano-1,6a-diaza-tetrahydro-fluoranthenes
JP2008528047A (ja) * 2005-02-04 2008-07-31 テイボテク・フアーマシユーチカルズ・リミテツド 競合的ｈｉｖのｒｔインヒビターのスクリーニング法
JP2009525310A (ja) * 2006-02-03 2009-07-09 テイボテク・フアーマシユーチカルズ・リミテツド 突然変異したｈｉｖを処置する方法
AU2007233737B2 (en) 2006-03-30 2012-11-29 Janssen Sciences Ireland Uc HIV inhibiting 5-amido substituted pyrimidines
WO2008037783A1 (en) * 2006-09-29 2008-04-03 Tibotec Pharmaceuticals Ltd. Process for preparing 2-oxo-2,5-dihydro-1h-pyrido[3,2-b]indole-3-carbonitriles
US9006243B2 (en) 2006-12-29 2015-04-14 Janssen R&D Ireland HIV inhibiting 6-substituted pyrimidines
US8318736B2 (en) 2006-12-29 2012-11-27 Janssen R&D Ireland HIV inhibiting 5,6-substituted pyrimidines
AR065720A1 (es) 2007-03-14 2009-06-24 Tibotec Pharm Ltd Polvos para reconstitucion que comprenden rilpivirina dispersos en ciertos polimeros. uso. proceso.
HRP20131128T1 (hr) 2007-07-12 2013-12-20 Janssen R&D Ireland Kristalni oblik (e) 4-[[4-[[4-(2-cijanoetenil)-2,6-dimetilfenil]amino]-2-pirimidinil]amino]benzonitrila
WO2010085581A1 (en) * 2009-01-23 2010-07-29 Bristol-Myers Squibb Company Substituted oxadiazole derivatives as s1p agonists in the treatment of autoimmune and inflammatory diseases
EP2389377B1 (en) * 2009-01-23 2014-07-16 Bristol-Myers Squibb Company Substituted oxadiazole derivatives as s1p agonists in the treatment of autoimmune and inflammatory diseases
ES2405054T3 (es) 2009-01-23 2013-05-30 Bristol-Myers Squibb Company Derivados de pirazol-1,2,4-oxadiazol como agonistas de esfingosina-1-fosfato
BRPI1014821A2 (pt) 2009-04-09 2016-04-05 Boehringer Ingelheim Int "inibidores de replicação de hiv"
EP2386541A1 (en) * 2010-05-14 2011-11-16 Affectis Pharmaceuticals AG Novel methods for the preparation of P2X7R antagonists
CN103025706A (zh) 2010-07-28 2013-04-03 住友化学株式会社 羧酸酰胺的制造方法
UA115576C2 (uk) 2012-12-06 2017-11-27 Байєр Фарма Акцієнгезелльшафт Похідні бензимідазолу як антагоністи ер4
CN108289448B (zh) * 2015-12-02 2021-10-22 先正达参股股份有限公司 杀微生物的噁二唑衍生物
EP3475275B1 (en) * 2016-06-23 2024-04-10 Merck Sharp & Dohme LLC 3-aryl and heteroaryl substituted 5-trifluoromethyl oxadiazoles as histone deacetylase 6 (hdac6) inhibitors
KR200486209Y1 (ko) 2016-07-05 2018-04-16 박우 편육 가공기구
CN108299428B (zh) * 2018-04-04 2019-09-27 山东大学 8-胺基-7-甲酸甲酯-吡嗪骈吡啶酮衍生物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002246659A1 (en) * 2000-12-18 2002-08-06 The Government Of The United States Of America, As Represented By The Secretary, Department Of Healt Benzoylalkylindolepyridinium compounds and pharmaceutical compositions comprising such compounds
WO2002055520A2 (en) * 2000-12-18 2002-07-18 Us Health Benzoylalkylindolepyridinium compounds and pharmaceutical compositions comprising such compounds

Also Published As

Publication number Publication date
AU2003296760A1 (en) 2004-06-15
EP1594870B1 (en) 2011-05-11
US20060173000A1 (en) 2006-08-03
MXPA05005146A (es) 2005-07-22
BR0316209A (pt) 2005-09-27
KR20050084621A (ko) 2005-08-26
HRP20050543A2 (en) 2006-09-30
US7608726B2 (en) 2009-10-27
WO2004046143A1 (en) 2004-06-03
EA009871B1 (ru) 2008-04-28
JP2006508145A (ja) 2006-03-09
NO20052884L (no) 2005-08-15
NO20052884D0 (no) 2005-06-14
AU2003296760B2 (en) 2009-11-19
AP1927A (en) 2008-12-10
US20100048563A1 (en) 2010-02-25
EA200500822A1 (ru) 2005-12-29
NZ540321A (en) 2007-09-28
CN1738816A (zh) 2006-02-22
CA2506316A1 (en) 2004-06-03
EP1594870A1 (en) 2005-11-16
CN100457754C (zh) 2009-02-04
AP2005003334A0 (en) 2005-06-30

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Legal Events

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