PL376683A1 - Podstawione indolopirydyny jako związki przeciwinfekcyjne - Google Patents

Podstawione indolopirydyny jako związki przeciwinfekcyjne

Info

Publication number
PL376683A1
PL376683A1 PL376683A PL37668303A PL376683A1 PL 376683 A1 PL376683 A1 PL 376683A1 PL 376683 A PL376683 A PL 376683A PL 37668303 A PL37668303 A PL 37668303A PL 376683 A1 PL376683 A1 PL 376683A1
Authority
PL
Poland
Prior art keywords
infective compounds
indolepyridinium
substituted
substituted indolepyridinium
infective
Prior art date
Application number
PL376683A
Other languages
English (en)
Inventor
Bart Rudolf Romanie Kesteleyn
De Vreken Wim Van
Natalie Maria Francisca Kindermans
Maxime Francis Jean-Marie Ghislain Canard
Kurt Hertogs
Eva Bettens
Vroey Veronique Corine Paul De
Dirk Edward Desire Jochmans
Original Assignee
Tibotec Pharmaceuticals Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharmaceuticals Ltd. filed Critical Tibotec Pharmaceuticals Ltd.
Publication of PL376683A1 publication Critical patent/PL376683A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL376683A 2002-11-15 2003-11-14 Podstawione indolopirydyny jako związki przeciwinfekcyjne PL376683A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02079783 2002-11-15
US43495002P 2002-12-20 2002-12-20

Publications (1)

Publication Number Publication Date
PL376683A1 true PL376683A1 (pl) 2006-01-09

Family

ID=32327852

Family Applications (1)

Application Number Title Priority Date Filing Date
PL376683A PL376683A1 (pl) 2002-11-15 2003-11-14 Podstawione indolopirydyny jako związki przeciwinfekcyjne

Country Status (16)

Country Link
US (2) US7608726B2 (pl)
EP (1) EP1594870B1 (pl)
JP (1) JP2006508145A (pl)
KR (1) KR20050084621A (pl)
CN (1) CN100457754C (pl)
AP (1) AP1927A (pl)
AU (1) AU2003296760B2 (pl)
BR (1) BR0316209A (pl)
CA (1) CA2506316A1 (pl)
EA (1) EA009871B1 (pl)
HR (1) HRP20050543A2 (pl)
MX (1) MXPA05005146A (pl)
NO (1) NO20052884L (pl)
NZ (1) NZ540321A (pl)
PL (1) PL376683A1 (pl)
WO (1) WO2004046143A1 (pl)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
US7622581B2 (en) * 2004-05-17 2009-11-24 Tibotec Pharmaceuticals Ltd. 6,7,8,9-substituted 1-phenyl-1,5-dihydro-pyrido[3,2-b]indol-2-ones useful as anti-infective pharmaceutical agents
CA2564027A1 (en) * 2004-05-17 2005-11-24 Tibotec Pharmaceuticals Ltd. 1-heterocyclyl-1,5-dihydro-pyrido[3,2-b]indol-2-ones
CN1953978B (zh) * 2004-05-17 2010-09-29 泰博特克药品有限公司 作为抗病毒剂的5-取代的1-苯基-1,5-二氢-吡啶并[3,2-b]吲哚-2-酮及其类似物
WO2005111044A1 (en) * 2004-05-17 2005-11-24 Tibotec Pharmaceuticals Ltd. 4-substituted-1,5-dihydro-pyrido[3,2-b]indol-2-ones
TW200612946A (en) * 2004-05-17 2006-05-01 Tibotec Pharm Ltd Combinations of substituted 1-phenyl-1,5-dihydro-pyrido-[3,2-b]indol-2-ones and other HIV inhibitors
JP5046943B2 (ja) 2004-09-30 2012-10-10 テイボテク・フアーマシユーチカルズ Ｈｉｖ阻害性５−置換ピリミジン
WO2006035067A2 (en) 2004-09-30 2006-04-06 Tibotec Pharmaceuticals Ltd. Hiv inhibiting 5-heterocyclyl pyrimidines
TW200637862A (en) * 2005-01-10 2006-11-01 Tibotec Pharm Ltd 1,5,6-substituted-2-oxo-3-cyano-1,6a-diaza-tetrahydro-fluoranthenes
EP1853720A1 (en) * 2005-02-04 2007-11-14 Tibotec Pharmaceuticals Ltd. Screening method for competitive hiv rt inhibitors
JP2009525310A (ja) * 2006-02-03 2009-07-09 テイボテク・フアーマシユーチカルズ・リミテツド 突然変異したｈｉｖを処置する方法
CN101405283B (zh) 2006-03-30 2014-06-18 泰博特克药品有限公司 Hiv抑制性5-酰氨基取代的嘧啶类化合物
WO2008037783A1 (en) * 2006-09-29 2008-04-03 Tibotec Pharmaceuticals Ltd. Process for preparing 2-oxo-2,5-dihydro-1h-pyrido[3,2-b]indole-3-carbonitriles
AU2007341227C1 (en) 2006-12-29 2013-08-29 Janssen Sciences Ireland Uc HIV inhibiting 6-substituted pyrimidines
AU2007341228B2 (en) 2006-12-29 2013-04-18 Janssen Sciences Ireland Uc HIV inhibiting 5,6-substituted pyrimidines
AR065720A1 (es) 2007-03-14 2009-06-24 Tibotec Pharm Ltd Polvos para reconstitucion que comprenden rilpivirina dispersos en ciertos polimeros. uso. proceso.
CA2693044C (en) 2007-07-12 2017-03-14 Tibotec Pharmaceuticals Crystalline form of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2 pyrimidinyl]amino]benzonitrile
JP2012515787A (ja) * 2009-01-23 2012-07-12 ブリストル−マイヤーズ スクイブ カンパニー 自己免疫疾患および炎症性疾患の処置におけるｓ１ｐアゴニストとしての置換オキサジアゾール誘導体
ES2405054T3 (es) 2009-01-23 2013-05-30 Bristol-Myers Squibb Company Derivados de pirazol-1,2,4-oxadiazol como agonistas de esfingosina-1-fosfato
WO2010085582A1 (en) * 2009-01-23 2010-07-29 Bristol-Myers Squibb Company Substituted oxadiazole derivatives as s1p agonists in the treatment of autoimmune and inflammatory diseases
BRPI1014821A2 (pt) 2009-04-09 2016-04-05 Boehringer Ingelheim Int "inibidores de replicação de hiv"
SG185400A1 (en) * 2010-05-14 2012-12-28 Affectis Pharmaceuticals Ag Novel methods for the preparation of p2x7r antagonists
EP2599769A4 (en) 2010-07-28 2015-05-20 Sumitomo Chemical Co PROCESS FOR PREPARING A CARBOXYLIC ACID AMID
UA115576C2 (uk) 2012-12-06 2017-11-27 Байєр Фарма Акцієнгезелльшафт Похідні бензимідазолу як антагоністи ер4
MX2018006474A (es) * 2015-12-02 2018-08-01 Syngenta Participations Ag Derivados de oxadiazol microbicidas.
WO2017222951A1 (en) * 2016-06-23 2017-12-28 Merck Sharp & Dohme Corp. 3-aryl and heteroaryl substituted 5-trifluoromethyl oxadiazoles as histone deacetylase 6 (hdac6) inhibitors
KR200486209Y1 (ko) 2016-07-05 2018-04-16 박우 편육 가공기구
CN108299428B (zh) * 2018-04-04 2019-09-27 山东大学 8-胺基-7-甲酸甲酯-吡嗪骈吡啶酮衍生物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002246658A1 (en) 2000-12-18 2002-07-24 Makarov, Vadim Benzoylalkylindolepyridinium compounds and pharmaceutical compositions comprising such compounds
WO2002059123A2 (en) 2000-12-18 2002-08-01 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Benzoylalkylindolepyridinium compounds and pharmaceutical compositions comprising such compounds

Also Published As

Publication number Publication date
MXPA05005146A (es) 2005-07-22
US20060173000A1 (en) 2006-08-03
EA009871B1 (ru) 2008-04-28
AU2003296760A1 (en) 2004-06-15
CN100457754C (zh) 2009-02-04
AP2005003334A0 (en) 2005-06-30
WO2004046143A1 (en) 2004-06-03
CA2506316A1 (en) 2004-06-03
EP1594870A1 (en) 2005-11-16
NO20052884D0 (no) 2005-06-14
AU2003296760B2 (en) 2009-11-19
US20100048563A1 (en) 2010-02-25
BR0316209A (pt) 2005-09-27
JP2006508145A (ja) 2006-03-09
KR20050084621A (ko) 2005-08-26
NZ540321A (en) 2007-09-28
US7608726B2 (en) 2009-10-27
HRP20050543A2 (en) 2006-09-30
AP1927A (en) 2008-12-10
NO20052884L (no) 2005-08-15
CN1738816A (zh) 2006-02-22
EP1594870B1 (en) 2011-05-11
EA200500822A1 (ru) 2005-12-29

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Legal Events

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