PL3898638T3 - Krystaliczne formy inhibitora par4 - Google Patents

Krystaliczne formy inhibitora par4

Info

Publication number
PL3898638T3
PL3898638T3 PL19842497.0T PL19842497T PL3898638T3 PL 3898638 T3 PL3898638 T3 PL 3898638T3 PL 19842497 T PL19842497 T PL 19842497T PL 3898638 T3 PL3898638 T3 PL 3898638T3
Authority
PL
Poland
Prior art keywords
crystalline forms
par4 inhibitor
par4
inhibitor
crystalline
Prior art date
Application number
PL19842497.0T
Other languages
English (en)
Inventor
Roxana F. Schlam
Nicolas Cuniere
Victoria A. MBACHU
Zhongping Shi
Petinka I. Vlahova
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=69187955&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3898638(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of PL3898638T3 publication Critical patent/PL3898638T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433Thidiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02Dicarboxylic acids
    • C07C55/10Succinic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235Saturated compounds containing more than one carboxyl group
    • C07C59/245Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/265Citric acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL19842497.0T 2018-12-21 2019-12-20 Krystaliczne formy inhibitora par4 PL3898638T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862783223P 2018-12-21 2018-12-21
PCT/US2019/067717 WO2020132381A1 (en) 2018-12-21 2019-12-20 Crystalline forms of a par4 inhibitor

Publications (1)

Publication Number Publication Date
PL3898638T3 true PL3898638T3 (pl) 2023-12-04

Family

ID=69187955

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19842497.0T PL3898638T3 (pl) 2018-12-21 2019-12-20 Krystaliczne formy inhibitora par4

Country Status (30)

Country Link
US (2) US12129264B2 (pl)
EP (1) EP3898638B1 (pl)
JP (1) JP7473554B2 (pl)
KR (1) KR20210109559A (pl)
CN (3) CN121021533A (pl)
AU (2) AU2019403348B2 (pl)
BR (1) BR112021011688A2 (pl)
CA (1) CA3124100A1 (pl)
CL (1) CL2021001590A1 (pl)
CO (1) CO2021008043A2 (pl)
DK (1) DK3898638T3 (pl)
EA (1) EA202191760A1 (pl)
ES (1) ES2964404T3 (pl)
FI (1) FI3898638T3 (pl)
HR (1) HRP20231527T1 (pl)
HU (1) HUE064830T2 (pl)
IL (2) IL320212A (pl)
LT (1) LT3898638T (pl)
MX (1) MX2021007417A (pl)
MY (1) MY206303A (pl)
PE (1) PE20211963A1 (pl)
PL (1) PL3898638T3 (pl)
PT (1) PT3898638T (pl)
RS (1) RS64900B1 (pl)
SA (1) SA521422311B1 (pl)
SG (1) SG11202106561RA (pl)
SI (1) SI3898638T1 (pl)
SM (1) SMT202300417T1 (pl)
WO (1) WO2020132381A1 (pl)
ZA (1) ZA202105115B (pl)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2841437T (pt) 2012-04-26 2017-09-28 Univ Montreal Derivados de imidazotiadiazol e imidazopirazina como inibidores de recetor 4 ativado por protease (par4) para o tratamento de agregação plaquetária

Also Published As

Publication number Publication date
IL320212A (en) 2025-06-01
EA202191760A1 (ru) 2021-10-07
CN113227102A (zh) 2021-08-06
KR20210109559A (ko) 2021-09-06
CN113227102B (zh) 2025-07-18
AU2019403348B2 (en) 2024-11-28
HRP20231527T1 (hr) 2024-04-26
HUE064830T2 (hu) 2024-04-28
US12129264B2 (en) 2024-10-29
ZA202105115B (en) 2024-02-28
DK3898638T3 (da) 2023-11-20
RS64900B1 (sr) 2023-12-29
SI3898638T1 (sl) 2023-12-29
US20250026767A1 (en) 2025-01-23
AU2019403348A1 (en) 2021-08-05
EP3898638A1 (en) 2021-10-27
EP3898638B1 (en) 2023-08-30
JP2022514624A (ja) 2022-02-14
WO2020132381A1 (en) 2020-06-25
PE20211963A1 (es) 2021-10-04
CN121021534A (zh) 2025-11-28
US20220064186A1 (en) 2022-03-03
SMT202300417T1 (it) 2024-01-10
AU2025201372A1 (en) 2025-03-20
IL284222B1 (en) 2025-05-01
IL284222A (en) 2021-08-31
JP7473554B2 (ja) 2024-04-23
SG11202106561RA (en) 2021-07-29
PT3898638T (pt) 2023-11-13
LT3898638T (lt) 2023-11-10
CO2021008043A2 (es) 2021-06-30
CA3124100A1 (en) 2020-06-25
CN121021533A (zh) 2025-11-28
SA521422311B1 (ar) 2024-04-15
IL284222B2 (en) 2025-09-01
MX2021007417A (es) 2021-08-05
FI3898638T3 (fi) 2023-11-15
ES2964404T3 (es) 2024-04-05
CL2021001590A1 (es) 2021-12-03
BR112021011688A2 (pt) 2021-09-08
MY206303A (en) 2024-12-07

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